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  1. 181
    “…We centred our study on the transcriptional activation of oncogenic miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375, miR‐451a and NF‐κB‐related genes, previously linked to acidic bile‐induced pre‐neoplastic events. …”
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    NF‐κB inhibition reverses acidic bile‐induced miR‐21, miR‐155, miR‐192, miR‐34a, miR‐375 and miR‐451a deregulations in human hypopharyngeal cells
  2. 182
    “…BACKGROUND: MicroRNAs (miRNAs) are small RNA molecules that post-transcriptionally regulate gene expression and have been shown to play an important role during development. miR-1, miR-133a, miR-133b and miR-206 are expressed in muscle tissue and induced during muscle cell differentiation, a process that directs myoblasts to differentiate into mature myotubes, which are organized into myofibers. …”
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    Expression of miR-1, miR-133a, miR-133b and miR-206 increases during development of human skeletal muscle
  3. 183
    “…BACKGROUND: MicroRNA (miR) miR-34a, -34b/c, -124-1 and -203 are tumor suppressor miRs implicated in carcinogenesis. …”
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    Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
  4. 184
    “…RESULTS: The profiles showed that 39 and 17 miRNAs are exclusively expressed in the serum of non-cancerous volunteers and of patients with nasopharyngeal carcinoma respectively. 4 miRNAs including miR-17, miR-20a, miR-29c, and miR-223 were found to be expressed differentially in the serum of NPC compared with that of non-cancerous control. …”
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    Circulating miR-17, miR-20a, miR-29c, and miR-223 Combined as Non-Invasive Biomarkers in Nasopharyngeal Carcinoma
  5. 185
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    4,4′-[(2R*,3R*,4R*,5R*)-3,4-Dimethyl­tetra­hydro­furan-2,5-di­yl]diphenol
  6. 186
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    (3R,3aR,6R,6aR)-Hexa­hydro­furo[3,2-b]furan-3,6-diyl dibenzoate
  7. 187
    “…Expression levels of miR-21, miR-34a and miR-198 were significantly higher, whereas levels of miR-217 were significantly lower in pancreatic ductal adenocarcinomas compared to healthy tissues and tissues of chronic pancreatitis. …”
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    MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma
  8. 188
    “…MiR-29c and miR-148 indicated good ability to distinguish between histological subtypes of esophageal cancer. …”
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    Diagnostic and prognostic potential of miR-21, miR-29c, miR-148 and miR-203 in adenocarcinoma and squamous cell carcinoma of esophagus
  9. 189
    “…Among these miRNAs, the expression level of miR-1238-3p was increased while miR-494, miR-6069, and miR-139-3p were decreased (p < 0.05, fold change > 2). …”
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    Altered Expressions of miR-1238-3p, miR-494, miR-6069, and miR-139-3p in the Formation of Chronic Brucellosis
  10. 190
    “…In the present study, a total of 114 R2R3MYB genes were first identified from moso bamboo genome and full-length non-chimeric (FLNC) reads. …”
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    The R2R3MYB Gene Family in Phyllostachys edulis: Genome-Wide Analysis and Identification of Stress or Development-Related R2R3MYBs
  11. 191
    por Hu, Jieyao, Liu, Chao, Liu, Lang, Li, Qibin
    Publicado 2018
    “…The results show that M-MOF-74 can adsorb more R32 and R134a than R1234yf and R1234ze, as the molecular structures of R32 and R134a are smaller than those of R1234yf and R1234ze. …”
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    Thermal Energy Storage of R1234yf, R1234ze, R134a and R32/MOF-74 Nanofluids: A Molecular Simulation Study
  12. 192
    “…These analyses revealed that the MYB3R1 transcription factor in M. notabilis (encoded by MnMYB3R1) binds to the MnPPO1 promoter region. …”
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    An R1R2R3 MYB Transcription Factor, MnMYB3R1, Regulates the Polyphenol Oxidase Gene in Mulberry (Morus notabilis)
  13. 193
    por Du, Gang, Ren, Chongren, Wang, Ju, Ma, Jun
    Publicado 2022
    “…Via integrated feature selection (IFS), we noticed that the MLP classifier constructed by the first four miRNAs (miR-654-5p, miR-126, miR-10b, and miR-144) had the highest Matthews correlation coefficient (MCC). …”
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    The Clinical Value of Blood miR-654-5p, miR-126, miR-10b, and miR-144 in the Diagnosis of Colorectal Cancer
  14. 194
    “…Our results also reproduced known preferences of tracers, namely, that MK6240 binds better to AD tau than CBD tau and PSP tau and that CBD2115, PI2620, and PMPBB3 are 4R tau binders. These findings fill in the well-sought-after knowledge gap in terms of these tracers’ potential binding mechanisms and will be important for the design of highly selective novel PET tracers for tauopathies.…”
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    Insight into the Binding of First- and Second-Generation PET Tracers to 4R and 3R/4R Tau Protofibrils
  15. 195
    “…[Image: see text] Thymine glycol (Tg), 5,6-dihydroxy-5,6-dihydrothymine, is formed in DNA by the reaction of thymine with reactive oxygen species. The 5R Tg lesion was incorporated site-specifically into 5′-d(G(1)T(2)G(3)C(4)G(5)Tg(6)G(7)T(8)T(9)T(10)G(11)T(12))-3′; Tg = 5R Tg. …”
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    Interconversion of the cis-5R,6S- and trans-5R,6R-Thymine Glycol Lesions in Duplex DNA
  16. 196
    “…The RNA-binding protein, HuR, associates with the HuR mRNA, but the consequences of this interaction are unknown. …”
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    Reduced nuclear export of HuR mRNA by HuR is linked to the loss of HuR in replicative senescence
  17. 197
    “…In previous studies, we described a TetR-type transcriptional repressor, kstR, that controls the expression of a number of genes involved in cholesterol catabolism. …”
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    Cholesterol utilization in mycobacteria is controlled by two TetR-type transcriptional regulators: kstR and kstR2
  18. 198
    “…CDK5R1 encodes p35, a specific activator of the serine/threonine kinase CDK5, which plays crucial roles in CNS development and maintenance. …”
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    The Role of miR-103 and miR-107 in Regulation of CDK5R1 Expression and in Cellular Migration
  19. 199
    “…In the crystal, O—H⋯O hydrogen bonds form C (2) (3)(14) R (2) (2)(14) motifs.…”
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    [(3R*,4R*,5R*)-2,3-Diphenyl­isoxazolidine-4,5-di­yl]dimethanol
  20. 200
    “…In this study, we used bioinformatic analyses to search for miRNAs that potentially target IGF1R. We identified specific target sites for miR-143 and miR-145 (miR-143/145) in the 3′-untranslated region (3′-UTR) of the IGF1R gene. …”
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    MiR-143 and MiR-145 Regulate IGF1R to Suppress Cell Proliferation in Colorectal Cancer
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