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1301Dramatic Number Variation of R Genes in Solanaceae Species Accounted for by a Few R Gene Subfamilies“…Most disease resistance genes encode nucleotide-binding-site (NBS) and leucine-rich-repeat (LRR) domains, and the NBS-LRR encoding genes are often referred to as R genes. Using newly developed approach, 478, 485, 1,194, 1,665, 2,042 and 374 R genes were identified from the genomes of tomato Heinz1706, wild tomato LA716, potato DM1-3, pepper Zunla-1 and wild pepper Chiltepin and tobacco TN90, respectively. …”
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1302por Zhang, Xiaoying, Gee, Harriet, Rose, Barbara, Lee, C. Soon, Clark, Jonathan, Elliott, Michael, Gamble, Jennifer R., Cairns, Murray J., Harris, Adrian, Khoury, Samantha, Tran, Nham“…The 3’UTR of PDCD4 contains three binding-sites for miR-499 and one for miR-21. Using a wild-type and truncated 3’UTR of PDCD4, we demonstrated that the initial suppression of PDCD4 was mediated by miR-21 whilst sustained suppression was mediated by miR-499. …”
Publicado 2016
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1303por Navarro, A, Pairet, S, Álvarez-Larrán, A, Pons, A, Ferrer, G, Longarón, R, Fernández-Rodríguez, C, Camacho, L, Monzó, M, Besses, C, Bellosillo, B“…According to the mutational status, three differentially expressed miRNAs, miR-15a (P=0.045), miR-150 (P=0.001) and miR-519a (P=0.036), were identified. …”
Publicado 2016
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1304por Park, Hoon Suk, Lim, Ji Hee, Kim, Min Young, Kim, Yaeni, Hong, You Ah, Choi, Sun Ryoung, Chung, Sungjin, Kim, Hyung Wook, Choi, Bum Soon, Kim, Yong Soo, Chang, Yoon Sik, Park, Cheol Whee“…Resveratrol prevented cultured HGECs from undergoing high-glucose-induced oxidative stress and apoptosis by activating the AMPK–SIRT1–PGC–1α axis and PPARα through increases in AdipoR1 and AdipoR2 expression. CONCLUSIONS: These results suggest that resveratrol prevents diabetic nephropathy by ameliorating lipotoxicity, oxidative stress, apoptosis and endothelial dysfunction via increasing AdipoR1 and AdipoR2 expression. …”
Publicado 2016
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1305por Tamaddon, Gholamhossein, Geramizadeh, Bita, Karimi, Mohammad Hossein, Mowla, Seyed Javad, Abroun, Said“…The greatest changes were detected in miR-4284 and miR-4484 level in patient’s lymphoma samples. …”
Publicado 2016
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1307“…CmeABC, a key component in resistance to toxic compounds including antimicrobials and bile salts, is also under negative regulation by CmeR, a TetR family transcriptional regulator. How CosR and CmeR interact in binding to the cmeABC promoter and how CosR senses oxidative stress are still unknown. …”
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1310por Urem, Mia, van Rossum, Teunke, Bucca, Giselda, Moolenaar, Geri F., Laing, Emma, Świątek-Połatyńska, Magda A., Willemse, Joost, Tenconi, Elodie, Rigali, Sébastien, Goosen, Nora, Smith, Colin P., van Wezel, Gilles P.“…OsdR, when activated by the sensory kinase OsdK (SCO0203), binds upstream of the DevR-controlled dormancy genes devR, hspX, and Rv3134c of M. tuberculosis. …”
Publicado 2016
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1311por Ge, Yong-Chun, Jin, Bo, Zeng, Cai-Hong, Zhang, Ming-Chao, Chen, Da-Cheng, Yin, Ru, Le, Wei-Bo“…We examined the prevalence of serum PLA2R antibody and characterized the expression of PLA2R and THSD7A in glomeruli in patients with MN and psoriasis. …”
Publicado 2016
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1312miR-125b and miR-100 Are Predictive Biomarkers of Response to Induction Chemotherapy in Osteosarcomapor Kubota, Daisuke, Kosaka, Nobuyoshi, Fujiwara, Tomohiro, Yoshida, Akihiko, Arai, Yasuhito, Qiao, Zhiwei, Takeshita, Fumitaka, Ochiya, Takahiro, Kawai, Akira, Kondo, Tadashi“…We found six miRNAs, including miR-125b and miR-100, that were differentially expressed > 2-fold (p < 0.05) in patients who respond poorly to treatment. …”
Publicado 2016
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1313por Varsos, Constantinos, Patkos, Theodore, Oulas, Anastasis, Pavloudi, Christina, Gougousis, Alexandros, Ijaz, Umer Zeeshan, Filiopoulou, Irene, Pattakos, Nikolaos, Vanden Berghe, Edward, Fernández-Guerra, Antonio, Faulwetter, Sarah, Chatzinikolaou, Eva, Pafilis, Evangelos, Bekiari, Chryssoula, Doerr, Martin, Arvanitidis, Christos“…BACKGROUND: Parallel data manipulation using R has previously been addressed by members of the R community, however most of these studies produce ad hoc solutions that are not readily available to the average R user. …”
Publicado 2016
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1314por de Melo Maia, Beatriz, Rodrigues, Iara Santana, Akagi, Erica Mie, Soares do Amaral, Nayra, Ling, Hui, Monroig, Paloma, Soares, Fernando Augusto, Calin, George Adrian, Rocha, Rafael Malagoli“…MiR-223-5p has been previously mentioned to be associated with tumor metastasis in HPV negative vulvar carcinomas, such as in several other tumor types. …”
Publicado 2016
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1315por Venø, Morten T., Venø, Susanne T., Rehberg, Kati, van Asperen, Jessy V., Clausen, Bettina H., Holm, Ida E., Pasterkamp, R. Jeroen, Finsen, Bente, Kjems, Jørgen“…Temporal miRNA profiling in the developing embryonic porcine cortex revealed a distinct set of miRNAs, including miR-34c and miR-204, which exhibited a highly specific expression profile across the time of cortical folding. …”
Publicado 2017
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1316por Dufour, Florent, Rattier, Thibault, Shirley, Sarah, Picarda, Gaelle, Constantinescu, Andrei Alexandru, Morlé, Aymeric, Zakaria, Al Batoul, Marcion, Guillaume, Causse, Sebastien, Szegezdi, Eva, Zajonc, Dirk Michael, Seigneuric, Renaud, Guichard, Gilles, Gharbi, Tijani, Picaud, Fabien, Herlem, Guillaume, Garrido, Carmen, Schneider, Pascal, Benedict, Chris Alan, Micheau, Olivier“…APO2L/TRAIL (TNF-related apoptosis-inducing ligand) induces death of tumor cells through two agonist receptors, TRAIL-R1 and TRAIL-R2. We demonstrate here that N-linked glycosylation (N-glyc) plays also an important regulatory role for TRAIL-R1-mediated and mouse TRAIL receptor (mTRAIL-R)-mediated apoptosis, but not for TRAIL-R2, which is devoid of N-glycans. …”
Publicado 2017
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1317“…OBJECTIVE: To determine the role of miR-484 and miR-744 in DENV infection and to examine whether DENV infection alters the expression of both miRNAs. …”
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1318por Liu, Kejian, Xuekelati, Saiyare, Zhang, Yue, Yin, Yin, Li, Yue, Chai, Rui, Li, Xinwei, Peng, Yi, Wu, Jiangdong, Guo, Xiaomei“…The aim of the current study is to investigate the expression levels of atherosclerosis-associated miR-143 and miR-145 in Hhcy patients and predict the progress of atherosclerosis in Hhcy patients. …”
Publicado 2017
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1319por Mercatelli, Neri, Fittipaldi, Simona, De Paola, Elisa, Dimauro, Ivan, Paronetto, Maria Paola, Jackson, Malcolm J., Caporossi, Daniela“…Interestingly, the forced inhibition of miR-23a and miR-23b during C2C12 differentiation partially rescues TrxR1 levels and delays the expression of myogenic markers, suggesting the involvement of miR-23 in myogenesis via TrxR1 repression. …”
Publicado 2017
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1320por Mociño-Rodríguez, Martha Daniela, Santillán-Benítez, Jonnathan Guadalupe, Dozal-Domínguez, David Salomón, Hernández-Navarro, María Dolores, Flores-Merino, Miriam Veronica, Sandoval-Cabrera, Antonio, García Vázquez, Francisco Javier“…However, there is little research concerning AdipoR1 and AdipoR2 receptors and the influence of leptin over them. …”
Publicado 2017
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