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1921Stenotrophomonas maltophilia responds to exogenous AHL signals through the LuxR solo SmoR (Smlt1839)por Martínez, Paula, Huedo, Pol, Martinez-Servat, Sònia, Planell, Raquel, Ferrer-Navarro, Mario, Daura, Xavier, Yero, Daniel, Gibert, Isidre“…Its genomic organization—adjacent to hchA gene—indicate that SmoR belongs to the new family “LuxR regulator chaperone HchA-associated.” …”
Publicado 2015
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1922por Du, Mulong, Shi, Danni, Yuan, Lin, Li, Pengchao, Chu, Haiyan, Qin, Chao, Yin, Changjun, Zhang, Zhengdong, Wang, Meilin“…A total of eight plasma miRNAs abnormally expressed between BC patients and healthy controls in microarray analysis (i.e., elevated miRNAs for miR-505, miR-363 and miR-663b, and decreased for miR-99a, miR-194, miR-100, miR-497 and miR-1 in BC plasma). …”
Publicado 2015
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1923por Ribeiro, Joana, Marinho-Dias, Joana, Monteiro, Paula, Loureiro, Joana, Baldaque, Inês, Medeiros, Rui, Sousa, Hugo“…We aimed to characterize miR-125b and miR-34a expression in 114 women with different cervical lesions: normal epithelium with (n = 20) and without (n = 29) HPV infection; LSIL (n = 28); HSIL (n = 29); and ICC (n = 8). miRNA expression analysis was performed by comparing the distinct groups with the reference group (women with normal epithelium without HPV). …”
Publicado 2015
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1924por Barry, Simone E, Chan, Brian, Ellis, Magda, Yang, YuRong, Plit, Marshall L, Guan, Guangyu, Wang, Xiaolin, Britton, Warwick J, Saunders, Bernadette M“…This study examined the appropriateness of 12 miRs and RNU6B to normalise circulating plasma miRNA levels in individuals with active TB from 2 different geographical and ethnic regions. Twelve miRs (let-7, miR-16, miR-22, miR-26, miR-93, miR-103, miR-191, miR-192, miR-221, miR-423, miR-425 and miR-451) and RNU6B were selected based on their reported production by lung cells, expression in blood and previous use as a reference miRNA. …”
Publicado 2015
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1925por Saad, Maarouf A., Kuo, Selena Z., Rahimy, Elham, Zou, Angela E., Korrapati, Avinaash, Rahimy, Mehran, Kim, Elizabeth, Zheng, Hao, Yu, Michael Andrew, Wang-Rodriguez, Jessica, Ongkeko, Weg M.“…Upon inhibition of these miRNAs, HNSCC cell lines exhibited increased sensitivity to cisplatin and reduced matrigel invasion. miRNA knockdown also indicated direct targeting of several tumor suppressor genes by miR-30a and miR-934. CONCLUSIONS: Alcohol induces the dysregulation of miR-30a and miR-934, which may play crucial roles in HNSCC pathogenesis and progression. …”
Publicado 2015
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1926por Li, Jincheng, Aung, Lynn Htet Htet, Long, Bo, Qin, Danian, An, Shejuan, Li, Peifeng“…Here, we report that miR-23a promotes the apoptotic effect of p53 in cardiomyocytes. …”
Publicado 2015
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1927por Chen, Hankui, Liu, Helu, Zou, Hanqing, Chen, Rui, Dou, Yuhong, Sheng, Shile, Dai, Shengming, Ai, Junmei, Melson, Joshua, Kittles, Rick A., Pirooznia, Mehdi, Liptay, Michael J., Borgia, Jeffrey A., Deng, Youping“…We observed significantly elevated expression of miR-21 and miR-152 in LuCa, CRC, and BrCa when compared with normal controls. …”
Publicado 2016
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1928por Clark, Amanda L., Maruyama, Sonomi, Sano, Soichi, Accorsi, Anthony, Girgenrath, Mahasweta, Walsh, Kenneth, Naya, Francisco J.“…Recently, we demonstrated that regulation of the Gtl2-Dio3 noncoding RNA locus is dependent on the MEF2 transcription factor in cardiac muscle, and that two of its encoded miRNAs, miR-410 and miR-495, induce robust cardiomyocyte proliferation. …”
Publicado 2016
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1929por Okada, Hironori, Ishibashi, Hidetoshi, Hayashita-Kinoh, Hiromi, Chiyo, Tomoko, Nitahara-Kasahara, Yuko, Baba, Yukihiro, Watanabe, Sumiko, Takeda, Shin'ichi, Okada, Takashi“…Profiles of recombinant adeno-associated virus (rAAV)-mediated transduction show interspecies differences for each AAV serotype. …”
Publicado 2013
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1930“…Most likely free IL2 binds first to IL2Rα, and then this complex binds to IL2Rβ, and finally to IL2Rγ (γc). …”
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1931por Park, Hoon Suk, Lim, Ji Hee, Kim, Min Young, Kim, Yaeni, Hong, You Ah, Choi, Sun Ryoung, Chung, Sungjin, Kim, Hyung Wook, Choi, Bum Soon, Kim, Yong Soo, Chang, Yoon Sik, Park, Cheol WheeEnlace del recurso
Publicado 2016
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1932por Khafaei, Mostafa, Samie, Shahram, Mowla, Seyed Javad, Alvanegh, Akbar Ghorbani, Mirzaei, Behnaz, Chavoshei, Somaye, Dorraj, Ghamar Soltan, Esmailnejad, Mostafa, Tavallaie, Mahmood, Nourani, Mohammadreza“…Comparative evaluation of miR-9 and miR-143 expression in urine samples was performed by Real Time PCR and Graph Pad software. …”
Publicado 2015
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1933miR-124a and miR-155 enhance differentiation of regulatory T cells in patients with neuropathic painpor Heyn, Jens, Luchting, Benjamin, Hinske, Ludwig C., Hübner, Max, Azad, Shahnaz C., Kreth, Simone“…RESULTS: We demonstrate that microRNAs (miRNAs) are involved in the differentiation of Tregs in neuropathic pain. We identify miR-124a and miR-155 as direct repressors of the histone deacetylase sirtuin1 (SIRT1) in primary human CD4(+) cells. …”
Publicado 2016
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1934por Mundalil Vasu, Mahesh, Anitha, Ayyappan, Takahashi, Taro, Thanseem, Ismail, Iwata, Keiko, Asakawa, Tetsuya, Suzuki, Katsuaki“…Initial screening results revealed that three (miR-489, miR-572 and miR-663a) and four (miR-320a, miR-489, miR-572 and miR-663a) miRNAs were up-regulated in SK-N-SH cells and SH-SY5Y cells, respectively, after 24 hours treatment of fluoxetine (1–25 μM). …”
Publicado 2016
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1935por Zhou, Hui, Peng, Qian, Zhao, Jianbo, Owiti, Albert, Ren, Fei, Liao, Liao, Wang, Lu, Deng, Xianbao, Jiang, Quan, Han, Yuepeng“…Here, we report the identification and functional characterization of eight flavonoid-related R2R3-MYB transcription factors, designated PpMYB10.2, PpMYB9, PpMYBPA1, Peace, PpMYB17, PpMYB18, PpMYB19, and PpMYB20, respectively, in peach flower transcriptome. …”
Publicado 2016
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1936“…The importance of 16S rRNA gene amplicon profiles for understanding the influence of microbes in a variety of environments coupled with the steep reduction in sequencing costs led to a surge of microbial sequencing projects. …”
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1937
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1938por Li, Xuyan, Xie, Xin, Li, Ji, Cui, Yuhai, Hou, Yanming, Zhai, Lulu, Wang, Xiao, Fu, Yanli, Liu, Ranran, Bian, Shaomin“…BACKGROUND: microRNA166 (miR166) is a highly conserved family of miRNAs implicated in a wide range of cellular and physiological processes in plants. miR166 family generally comprises multiple miR166 members in plants, which might exhibit functional redundancy and specificity. …”
Publicado 2017
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1939por Mishra, Nibha, Friedson, Lyndon, Hanin, Geula, Bekenstein, Uriya, Volovich, Meshi, Bennett, Estelle R., Greenberg, David S., Soreq, Hermona“…Using surface plasmon resonance (SPR), we identified preferential miR-132 targeting of soluble AChE-R over synaptic-bound AChE-S, potentiating miR-132-mediated brain and body cholinergic suppression of pro-inflammatory cytokines. …”
Publicado 2017
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1940por Grossi, Ilaria, Arici, Bruna, Portolani, Nazario, Petro, Giuseppina De, Salvi, Alessandro“…In this study, we have evaluated the expression of miR-23b and miR-193a in a large cohort of 59 and 67 HCC patients, respectively. miR-23b and miR-193a resulted significantly down-regulated in primary HCCs compared to their matched peritumoral counterparts. …”
Publicado 2016
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