Mostrando 241 - 260 Resultados de 5,191 Para Buscar '"RBD"', tiempo de consulta: 0.13s Limitar resultados
  1. 241
    “…Herein, we present a safe cell-based ELISA-virus neutralization test (cbE-VNT) as a surrogate for the conventional viral neutralization assays that detects the inhibition of SARS-CoV-2 RBD binding to ACE2-bearing cells independently of species. …”
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    A cell-based ELISA as surrogate of virus neutralization assay for RBD SARS-CoV-2 specific antibodies
  2. 242
    “…The avidity index (AI) of IgG to the RBD of SARS-CoV-2 was determined for 71 patients with a mild (outpatient) course of COVID-19, including 39 primarily and 36 secondarily reinfected, and 92 patients with a severe (hospital) course of COVID-19, including 82 primarily and 10 secondarily infected. …”
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    Avidity of IgG to SARS-CoV-2 RBD as a Prognostic Factor for the Severity of COVID-19 Reinfection
  3. 243
    “…Therefore, investigations into the RBD mutations that disrupt neutralization through convalescent antibodies are urgently required. …”
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    Antigen–Antibody Complex-Guided Exploration of the Hotspots Conferring the Immune-Escaping Ability of the SARS-CoV-2 RBD
  4. 244
    “…When considering emerging variations in Southeast Asia, 14 dominant mutations were analyzed by applying the structural and energetic characterization using MD simulations. The ones in the RBD region displayed higher affinity to ACE2 due to the improved interfacial stability of the RBD β-strand surrounding the ACE2 across salt bridge hotspots. …”
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    Mutational scanning of spike RBD protein for enhanced ACE2 affinity emerging Southeast Asia in the late transmission phase
  5. 245
    “…Of the 168 S1-reactive sera, 8.33% (n = 14) have detectable RBD-specific antibodies and 6.55% (n = 11) NCP-specific antibodies. …”
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    Neutralising SARS-CoV-2 RBD-specific antibodies persist for at least six months independently of symptoms in adults
  6. 246
    “…However, the interacting residues of RBD are found to be the same in Lamda (C.37) variant. …”
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    Analyzing the interaction of human ACE2 and RBD of spike protein of SARS-CoV-2 in perspective of Omicron variant
  7. 247
    “…Our exploratory study supports further improvement of the RBD-based vaccine to prevent zoonotic spillover of MERS-CoV. …”
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    Protective efficacy of an RBD-based Middle East respiratory syndrome coronavirus (MERS-CoV) particle vaccine in llamas
  8. 248
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    Author Correction: A synthetic nanobody targeting RBD protects hamsters from SARS-CoV-2 infection
  9. 249
    “…The RBD protein was expressed in insect cells and purified by chromatography until >95% purity. …”
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    Squalene in oil-based adjuvant improves the immunogenicity of SARS-CoV-2 RBD and confirms safety in animal models
  10. 250
    “…In addition, anti-S1-RBD IgG purified from S1-RBD hyperimmune rabbit sera could cross-react with both DENV envelope protein (E) and nonstructural protein 1 (NS1). …”
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    Antibodies against the SARS-CoV-2 S1-RBD cross-react with dengue virus and hinder dengue pathogenesis
  11. 251
    “…We analyzed the nucleotide sequence of the Receptor Binding Domain (RBD) region of SARS-CoV-2 by the Sanger sequencing using in-house developed methods. …”
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    Genomic surveillance of SARS-CoV-2 by sequencing the RBD region using Sanger sequencing from North Kerala
  12. 252
    “…Western blotting results show that nine mutants of the RBD protein had strong antigenic activity in vitro. …”
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    Enhancing the Immunogenicity of RBD Protein Variants through Amino Acid E484 Mutation in SARS-CoV-2
  13. 253
    “…CONCLUSION: Our findings showed that RBD is of great importance in vaccine design and it can be used to develop recombinant vaccines through induction of antibodies against RBD.…”
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    Recombinant expression of SARS-CoV-2 receptor binding domain (RBD) in Escherichia coli and its immunogenicity in mice
  14. 254
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    SARS-CoV-2 Spike Protein (RBD) Subunit Adsorption at Abiotic Surfaces and Corona Formation at Polymer Particles
  15. 255
    “…Herein a recombinant chimeric antigen called LTB-RBD is described, which comprises the B subunit of the heat-labile enterotoxin from E. coli and a segment of the RBD from SARS-CoV-2 (aa 439-504, carrying B and T cell epitopes) from the Wuhan sequence and the variant of concern (VOC)—delta. …”
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    Production and Purification of LTB-RBD: A Potential Antigen for Mucosal Vaccine Development against SARS-CoV-2
  16. 256
    “…Using this RBD-grafted SpyCage scaffold (RBD+SpyCage), we performed two unadjuvanted intranasal vaccination studies in the “gold-standard” preclinical Syrian hamster model. …”
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    Intranasal SARS-CoV-2 RBD decorated nanoparticle vaccine enhances viral clearance in the Syrian hamster model
  17. 257
    “…In this study, we report the production and purification process of the receptor-binding domain (RBD) of SARS-CoV-2 in HEK293 cells, which allowed the design, optimization, and validation of an indirect ELISA (iELISA) for the detection of human anti-RBD antibodies. …”
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    Design and optimization of an IgG human ELISA assay reactive to recombinant RBD SARS-CoV-2 protein
  18. 258
    “…Here, we showed that dimeric S(RBD)-Fc and tetrameric 2xS(RBD)-Fc fusion proteins bind ACE2 with different affinity and block SARS-CoV-2 pseudoviral infection. …”
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    SARS-CoV-2 tetrameric RBD protein blocks viral infection and induces potent neutralizing antibody response
  19. 259
    “…In this work, we present the development of a simplified system that would afford to study the change in the SARS-CoV-2 S RBD/ACE2 binding related to the frequent mutations. …”
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    Structural analysis of a simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site
  20. 260
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    Natural IgG against S-Protein and RBD of SARS-CoV-2 Do Not Bind and Hydrolyze DNA and Are Not Autoimmune
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