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3561por Rojas-Jiménez, Gabriel, Solano, Daniela, Segura, Álvaro, Sánchez, Andrés, Chaves-Araya, Stephanie, Herrera, María, Vargas, Mariángela, Cerdas, Maykel, Calvo, Gerardo, Alfaro, Jonathan, Molina, Sebastián, Bolaños, Kimberly, Moreira-Soto, Andrés, Villalta, Mauren, Sánchez, Adriana, Cordero, Daniel, Durán, Gina, Solano, Gabriela, Gómez, Aarón, Hernández, Andrés, Sánchez, Laura, Vargas, Marco, Drexler, Jean Felix, Alape-Girón, Alberto, Díaz, Cecilia, León, Guillermo“…Moreover, the concentration of anti-RBD and ACE2-RBD neutralizing antibodies was higher in VP-IVIg than in CP-IVIg. …”
Publicado 2022
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3562por Bhatt, Anant Narayan, Kumar, Abhishek, Rai, Yogesh, Kumari, Neeraj, Vedagiri, Dhiviya, Harshan, Krishnan H., Chinnadurai, Vijayakumar, Chandna, Sudhir“…The progeny virions produced from 2-DG treated cells were found unglycosylated at crucial N-glycosites (N331 and N343) of the receptor-binding domain (RBD) in the spike protein, resulting in production of defective progeny virions with compromised infective potential. …”
Publicado 2022
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3563por Ko, Yi-Feng, Kuo, Pei-Hsin, Wang, Ching-Fu, Chen, Yu-Jen, Chuang, Pei-Chi, Li, Shih-Zhang, Chen, Bo-Wei, Yang, Fu-Chi, Lo, Yu-Chun, Yang, Yi, Ro, Shuan-Chu Vina, Jaw, Fu-Shan, Lin, Sheng-Huang, Chen, You-Yin“…Rapid eye movement (REM) sleep behavior disorder (RBD) is associated with Parkinson’s disease (PD). …”
Publicado 2022
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3564por Bharathi, Muruganantham, Sivamaruthi, Bhagavathi Sundaram, Kesika, Periyanaina, Thangaleela, Subramanian, Chaiyasut, Chaiyavat“…The standard drugs (ceftriaxone and cefuroxime) showed no or less inhibitory effect against RBD of omicron B.1.1.529. The present study also emphasized the pharmacological properties of the considered chemical compounds. …”
Publicado 2022
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3565“…The receptor-binding domain (RBD) of SARS-CoV-2 binds to receptor ACE2 in humans and animal species with high affinity, suggesting there have been adaptive genomic variants. …”
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3566por Angkasekwinai, Nasikarn, Sewatanon, Jaturong, Niyomnaitham, Suvimol, Phumiamorn, Supaporn, Sukapirom, Kasama, Sapsutthipas, Sompong, Sirijatuphat, Rujipas, Wittawatmongkol, Orasri, Senawong, Sansnee, Mahasirimongkol, Surakameth, Trisiriwanich, Sakalin, Chokephaibulkit, Kulkanya“…Immunogenicity was determined by IgG antibodies levels against receptor binding domain (RBD) of the SARS-CoV-2 spike protein (S1 subunit) and the 50% plaque reduction neutralization titers against various strains. …”
Publicado 2022
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3567por Ntouros, Panagiotis A., Kravvariti, Evrydiki, Vlachogiannis, Nikolaos I., Pappa, Maria, Trougakos, Ioannis P., Terpos, Evangelos, Tektonidou, Maria G., Souliotis, Vassilis L., Sfikakis, Petros P.“…In particular, a strong inverse correlation of individual pre-vaccination DSB levels with both the respective anti-S-RBD-IgG antibodies titers (r = −0.867) and neutralizing capacity of circulating anti-SARS-CoV-2 antibodies (r = −0.983) among the 9 older adults was evident. …”
Publicado 2022
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3568por Szabo, Miklos, Sarkozy, Daniel, Szigeti, Marton, Farsang, Robert, Kardos, Zsofia, Kozma, Adam, Csanky, Eszter, Chung, Doo Soo, Szekanecz, Zoltan, Guttman, Andras“…The receptor-binding domain (RBD) of the Spike protein expressed on the surface of the virus plays a key role in the viral entry into the host cell via the angiotensin-converting enzyme 2 receptor. …”
Publicado 2022
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3569por Tau, Luba, Turner, Dan, Adler, Amos, Marom, Rotem, Ahsanov, Svetlana, Matus, Natasha, Levi, Inbar, Gerber, Gal, Lev, Shir, Ziv-Baran, Tomer, Hagin, David, Freund, Tal, Grupper, Ayelet, Halperin, Tamar“…RESULTS: One hundred thirty-six PWH who completed 2 doses of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine were tested for anti-RBD IgG and compared with 61 vaccinated health care workers (HCWs). …”
Publicado 2022
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3570“…Here, an attempt has been made through in-silico screening of 55 bioactive compounds from two selected plants, Saussurea costus and Saussurea involucrata as potential inhibitors of two viral proteases, main protease Mpro (PDB ID:6LU7) and the RBD of SGP of Sars-CoV-2 B1.617.2 Delta variant (PDB ID:7ORB) where the binding energy, molecular interactions, ADMET/Tox, chemical descriptors and Quantum-Chemical Calculations were explored. …”
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3571por Nelli, Fabrizio, Fabbri, Agnese, Panichi, Valentina, Giannarelli, Diana, Topini, Giuseppe, Giron Berrios, Julio R., Virtuoso, Antonella, Marrucci, Eleonora, Mazzotta, Marco, Schirripa, Marta, Signorelli, Carlo, Chilelli, Mario G., Primi, Francesca, Silvestri, Maria A., Ruggeri, Enzo M.“…A significant positive linear correlation was shown when anti-RBD-S1 IgG titers were compared to these lymphocyte subset counts. …”
Publicado 2022
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3572por Szebeni, Gábor J., Gémes, Nikolett, Honfi, Dániel, Szabó, Enikő, Neuperger, Patrícia, Balog, József Á., Nagy, Lajos I., Szekanecz, Zoltán, Puskás, László G., Toldi, Gergely, Balog, Attila“…The rate of positive anti-RBD antibody response for healthy controls versus patients after 4 months post vaccination was 69% vs. 55% for the inactivated viral vaccine BBIBP-CorV, 97% vs. 53% for the pooled data of adenovirus vector-based vaccines Gam-COVID-Vac and AZD1222, or 100% vs. 81% for the pooled data of mRNA vaccines BNT162b2 and mRNA-1273, respectively. …”
Publicado 2022
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3573por Chansaenroj, Jira, Yorsaeng, Ritthideach, Puenpa, Jiratchaya, Wanlapakorn, Nasamon, Chirathaworn, Chintana, Sudhinaraset, Natthinee, Sripramote, Manit, Chalongviriyalert, Piti, Jirajariyavej, Supunee, Kiatpanabhikul, Phatharaporn, Saiyarin, Jatuporn, Soudon, Chulikorn, Thienfaidee, Orawan, Ayuthaya, Thitisan Palakawong Na, Brukesawan, Chantapat, Intharasongkroh, Duangnapa, Chaiwanichsiri, Dootchai, Issarasongkhram, Mila, Kitphati, Rungrueng, Mungaomklang, Anek, Thitithanyanont, Arunee, Nagavajara, Pijaya, Poovorawan, Yong“…The seropositivity rate of anti-S1 IgG, anti-RBD total Ig, anti-S1 IgA, and neutralizing titers remained at 68.6%, 89.6%, 77.1%, and 85.4%, respectively, at 12 months after symptom onset. …”
Publicado 2022
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3574por Wang, Zhongfang, Yang, Xiaoyun, Mei, Xinyue, Zhou, Yumin, Tang, Zhiqiang, Li, Guichang, Zhong, Jiaying, Yu, Mengqiu, Huang, Mingzhu, Su, Xiaoling, Lin, Bijia, Cao, Pengxing, Yang, Ji, Ran, Pixin“…Here, we measured different plasm antibody levels 2 and 12 months after disease onset, including anti-RBD, anti-N, total neutralizing antibodies, and two neutralizing-antibody clusters. …”
Publicado 2022
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3575por Wilkins, Deidre, Aksyuk, Anastasia A, Ruzin, Alexey, Tuffy, Kevin M, Green, Tina, Greway, Rebecca, Fikes, Brittany, Bonhomme, Cyrille J, Esser, Mark T, Kelly, Elizabeth J“…Clinical sensitivities for S, RBD and N antigens were 100%, 98.8% and 84.9%, respectively. …”
Publicado 2022
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3576por Kongsuphol, Patthara, Jia, Huan, Cheng, Hoi Lok, Gu, Yue, Shunmuganathan, Bhuvaneshwari D/O, Chen, Ming Wei, Lim, Sing Mei, Ng, Say Yong, Tambyah, Paul Ananth, Nasir, Haziq, Gao, Xiaohong, Tay, Dousabel, Kim, Seunghyeon, Gupta, Rashi, Qian, Xinlei, Kozma, Mary M., Purushotorman, Kiren, McBee, Megan E., MacAry, Paul A., Sikes, Hadley D., Preiser, Peter R.“…Importantly, the approach used for this test can be easily extended to test RBD variants or to evaluate NAbs against other pathogens.…”
Publicado 2021
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3577por Figueiredo, Jane C., Merin, Noah M., Hamid, Omid, Choi, So Yung, Lemos, Tucker, Cozen, Wendy, Nguyen, Nathalie, Finster, Laurel J., Foley, Joslyn, Darrah, Justin, Gong, Jun, Paquette, Ronald, Mita, Alain C., Vescio, Robert, Mehmi, Inderjit, Basho, Reva, Tourtellotte, Warren G., Huynh, Carissa A., Melmed, Gil Y., Braun, Jonathan, McGovern, Dermot P.B., Mengesha, Emebet, Botwin, Greg, Prostko, John C., Frias, Edwin C., Stewart, James L., Joung, Sandy, Van Eyk, Jennifer, Ebinger, Joseph E., Cheng, Susan, Sobhani, Kimia, Reckamp, Karen L., Merchant, Akil“…In a prospective cohort study of 366 (291 vaccinated) patients, we measured antibody levels [anti-spike (IgG-(S-RBD) and anti-nucleocapsid immunoglobulin] at three time points. …”
Publicado 2021
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3578por Cantoni, Diego, Mayora-Neto, Martin, Thakur, Nazia, Elrefaey, Ahmed M. E., Newman, Joseph, Vishwanath, Sneha, Nadesalingam, Angalee, Chan, Andrew, Smith, Peter, Castillo-Olivares, Javier, Baxendale, Helen, Charleston, Bryan, Heeney, Jonathan, Bailey, Dalan, Temperton, Nigel“…The spike receptor binding domain (RBD) of RaTG13 contains a number of amino acid substitutions when compared to SARS-CoV-2, likely impacting affinity for the ACE2 receptor. …”
Publicado 2022
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3579por Yang, Su Lan, Mat Ripen, Adiratna, Leong, Chin Tho, Lee, Jen Ven, Yen, Chia How, Chand, Avinash Kumar, Koh, Karina, Abdul Rahim, Nur Aisyah Binti, Gokilavanan, Varaalakshmy, Mohamed, Nik Nur Eliza binti, Sevalingam, Raj Kumar A/L., Sulaiman, Nadirah, Ab Razak, Ahmad Kamil bin, Mohd Nor, Nurul Haslinda binti, Pong, Mei Kuan, Tai, Ket Yan, Toh, Valerie, Woon, Yuan Liang, Peariasamy, Kalaiarasu M.“…We investigated the association between anti-spike-1 protein receptor-binding domain (anti-S1-RBD) antibody geometric mean titre (GMT) and breakthrough infections. …”
Publicado 2022
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3580por Jeewandara, Chandima, Aberathna, Inoka Sepali, Pushpakumara, Pradeep Darshana, Kamaladasa, Achala, Guruge, Dinuka, Wijesinghe, Ayesha, Gunasekera, Banuri, Ramu, Shyrar Tanussiya, Kuruppu, Heshan, Ranasinghe, Thushali, Dayarathna, Shashika, Dissanayake, Osanda, Gamalath, Nayanathara, Ekanayake, Dinithi, Jayamali, Jeewantha, Jayathilaka, Deshni, Dissanayake, Madushika, Jayadas, Tibutius Thanesh, Mudunkotuwa, Anushika, Somathilake, Gayasha, Harvie, Michael, Nimasha, Thashmi, Danasekara, Saubhagya, Wijayamuni, Ruwan, Schimanski, Lisa, Rijal, Pramila, Tan, Tiong K., Dong, Tao, Townsend, Alain, Ogg, Graham S., Malavige, Gathsaurie Neelika“…Angiotensin‐converting enzyme 2 (ACE2) receptor blocking antibodies (ACE2R‐Ab), antibodies to the receptor‐binding domain (RBD) of the ancestral virus (WT) and variants of concern, were measured in a sub cohort. …”
Publicado 2022
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