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  1. 3641
    “…Antibody response was measured by anti-receptor-binding domain (RBD)-IgG detection, cell-mediated response by an interferon (IFN)-γ release assay (IGRA), Th1 cytokines and T-cell memory profile by flow cytometry. …”
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    Longitudinal characterisation of B and T-cell immune responses after the booster dose of COVID-19 mRNA-vaccine in people with multiple sclerosis using different disease-modifying therapies
  2. 3642
    “…The anti-receptor binding domain (RBD) antibody levels after the second booster dose in the WT and WT+BA.1 group were similar (median [interquartile range], 26,262.0 [16,951.0 to 38,137.0] U/mL versus 24,840.0 [14,828.0 to 41,460.0] U/mL, respectively). …”
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    Neutralizing Antibody Response of the Wild-Type/Omicron BA.1 Bivalent Vaccine as the Second Booster Dose against Omicron BA.2 and BA.5
  3. 3643
    “…We prospectively evaluated Ab and CMI response to mRNA vaccines in 103 SARS-CoV-2-naïve MM patients (median age 66, 1 median prior line of therapy) and 63 health-workers. Anti-S-RBD IgG (Elecsys(®)assay) were measured before vaccination and after 1 (T1), 3 (T3), 6 (T6), 9 (T9) and 12 (T12) months from second dose (D2) and 1 month after the introduction of the booster dose (T1D3). …”
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    Long term follow-up of humoral and cellular response to mRNA-based vaccines for SARS-CoV-2 in patients with active multiple myeloma
  4. 3644
    “…Both sensitivity and specificity were equal to 100% (89.85–100) for S1, RBD and N (S2 had a lower specificity = 95%) for IgG at day 14 after enrolment. …”
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    Using a multiplex serological assay to estimate time since SARS-CoV-2 infection and past clinical presentation in malagasy patients
  5. 3645
    “…METHODS: Receptor-binding domain-fragment crystallizable (RBD-Fc) and angiotensin-converting enzyme 2-histidine tag (ACE2-His) were expressed by the eukaryotic expression systems of Spodoptera frugiperda clone 9 and human embryonic kidney 293T, respectively. …”
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    Development of an Effective Neutralizing Antibody Assay for SARS-CoV-2 Diagnosis
  6. 3646
    “…Here, we present a seroprevalence study of anti-SARS-CoV-2 spike/RBD IgG in 1,121 health care workers immunized with Sputnik V and a follow-up of humoral response at 2 and 24 weeks postvaccination (wpv), including neutralizing antibody response (NAT) against ancestral, Gamma, and Delta variants. …”
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    Longitudinal Follow-Up of the Immunity to SARS-CoV-2 in Health Care Workers in Argentina: Persistence of Humoral Response and Neutralizing Capacity after Sputnik V Vaccination
  7. 3647
    “…The interactions of C1q, its recombinant globular heads, and C4BP with the SARS-CoV-2 spike and receptor binding domain (RBD) were examined using direct ELISA. In addition, RT-qPCR was used to evaluate the modulatory effect of these complement proteins on the SARS-CoV-2-mediated immune response. …”
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    Complement Activation-Independent Attenuation of SARS-CoV-2 Infection by C1q and C4b-Binding Protein
  8. 3648
    “…RESULTS: LP-PWH showed at T1 and T2 significant increase of: S-specific memory and circulating T follicular helper (cTfh) CD4(+) T cells; polyfunctional Th1-cytokine (IFN-γ, TNF-α, IL-2)- and Th2-cytokine (IL-4)-producing S-specific CD4(+) T cells; anti-RBD antibodies and spike-ACE2 binding inhibition activity. …”
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    Six-month immune responses to mRNA-1273 vaccine in combination antiretroviral therapy treated late presenter people with HIV according to previous SARS-CoV-2 infection
  9. 3649
    “…Among four of the most promising neutralizing hAbs (RBD-hAb-B22, -B23, -B25 and -B34), RBD-hAb-B22 exhibited the most potent and broad neutralization profiles across Omicron subvariant pseudoviruses, with low IC(50) values (7.7–41.6 ng/mL) and a low PRNT(50) value (3.8 ng/mL) in plaque assays with authentic BA.5. …”
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    Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2
  10. 3650
    “…No significant difference in anti-receptor binding domain (RBD) IgG were observed across arms at 2 weeks after the second dose. …”
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    Immunogenicity and reactogenicity of heterologous COVID-19 vaccination in pregnant women
  11. 3651
    “…Gold nanoparticles/tungsten oxide/carbon nanotubes (AuNPs/WO(3)/CNTs) were used as the active working sensor surface to support the chemical immobilization of a mixture of SARS-CoV-2 antibodies (anti-RBD-S and anti-RBD-S-anti-Llama monoclonal antibodies). …”
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    Double-antibody-based nano-biosensing system for the onsite monitoring of SARS-CoV-2 variants
  12. 3652
    “…We also confirmed that Nb-H6 binds two distinct amino acid residues of the RBD, preventing SARS-CoV-2 from interacting with the host receptor. …”
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    A Naïve Phage Display Library-Derived Nanobody Neutralizes SARS-CoV-2 and Three Variants of Concern
  13. 3653
    por Zhang, Chi-Yu, Wei, Ji-Fu, He, Shao-Heng
    Publicado 2006
    “…Moreover, it was showed that a larger proportion (24%) of positively selected sites was located in receptor-binding domain (RBD) than in heptad repeat (HR)1-HR2 region in 02–04 interspecies epidemic group (p = 0.0208), and a greater percentage (25%) of these sites occurred in HR1–HR2 region than in RBD in 03-early-mid epidemic group (p = 0.0721). …”
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    Adaptive evolution of the spike gene of SARS coronavirus: changes in positively selected sites in different epidemic groups
  14. 3654
    “…The PinPoint-3D ion chamber presented lower accuracy for the 6FFF beam. Regarding the RBD, calculations compared well with the input data used for the configuration, but not with the reference data. …”
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    The impact of scanning data measurements on the Acuros dose calculation algorithm configuration
  15. 3655
    “…A two-step IgG ELISA based on the receptor binding domain (RBD) and spike protein was adapted to determine seropositivity, and neutralising antibodies that block the RBD/hACE‑2 interaction were quantified by sVNT. …”
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    Collaborative networks enable the rapid establishment of serological assays for SARS-CoV-2 during nationwide lockdown in New Zealand
  16. 3656
    “…The three-dimensional structure of the KGDFR hosting protein region involved in direct interactions with SARS-CoV-2 spike RBD of the mink ACE2 appears to form a loop structurally related to the human ACE2 corresponding protein loop, despite of the reduced available protein length (401 residues of the mink ACE2 available sequence vs 805 residues of the human ACE2). …”
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    Highly conserved binding region of ACE2 as a receptor for SARS-CoV-2 between humans and mammals
  17. 3657
    “…Several highly neutralizing mAbs engaging the receptor binding domain (RBD) or N-terminal domain (NTD) lost inhibitory activity against Wash SA-B.1.351 or recombinant variants with an E484K spike mutation. …”
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    SARS-CoV-2 variants show resistance to neutralization by many monoclonal and serum-derived polyclonal antibodies
  18. 3658
    “…Kinetics of total anti-S receptor binding domain immunoglobulins (Ig anti–S RBD), anti-nucleoprotein (anti-N) and neutralizing antibodies were determined in serial serum samples retrieved during both infection episodes. …”
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    Clinical, virologic and immunologic features of a mild case of SARS-CoV-2 reinfection
  19. 3659
    “…With the EuroImmun (S) and receptor-binding domain (RBD) assays, responses increased for 4 weeks then fell until week 12–16 before stabilising. …”
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    Serological surveillance of SARS-CoV-2: Six-month trends and antibody response in a cohort of public health workers
  20. 3660
    “…Those of current concern harbor mutations within the spike receptor binding domain (RBD) that may be associated with viral escape to immune responses. …”
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    Implementation of an in-house real-time reverse transcription-PCR assay for the rapid detection of the SARS-CoV-2 Marseille-4 variant
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