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3681por Li, Yuchang, Wang, Mingyue, Wu, Hongzhen, Zhao, Hui, Dong, Lei, Li, Yunfei, Li, Xiaofeng, Tang, Ying, Zhang, Sen, Li, Jing, Qin, Chengfeng, Jiang, Tao, Deng, Yongqiang, Kang, Xiaoping“…METHODS: Based on the fact that antibodies exhibit neutralizing activity by blocking the binding of the S protein receptor-binding domain (S-RBD) to ACE2, we developed a rapid neutralizing antibody test, ACE2-Block-ELISA. …”
Publicado 2022
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3682por Abhishek, Abhishek, Boyton, RJ, McKnight, Áine, Coates, Laura, Bluett, James, Barber, Vicki S, Cureton, Lucy, Francis, Anne, Appelbe, Duncan, Eldridge, Lucy, Julier, Patrick, Peckham, Nicholas, Valdes, Ana M, Rombach, Ines, Altmann, Daniel M, Nguyen-Van-Tam, Jonathan, Williams, Hywel C, Cook, Jonathan Alistair“…The difference between the study arms in anti-spike RBD antibody level will be estimated using mixed effects model, allowing for repeated measures clustered within participants. …”
Publicado 2022
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3683por Yu, Ding, Li, Yu‐Feng, Liang, Hong, Wu, Jun‐Zheng, Hu, Yong, Peng, Yan, Li, Tao‐Jing, Hou, Ji‐Feng, Huang, Wei‐Jin, Guan, Li‐Dong, Han, Ren, Xing, Yan‐Tao, Zhang, Yong, Liu, Jia, Feng, Lu, Li, Chun‐Yan, Liang, Xiao‐Long, Ding, Ya‐Ling, Zhou, Zhi‐Jun, Ji, De‐Ming, Wang, Fei‐Fei, Yu, Jian‐Hong, Deng, Kun, Xia, Dong‐Mei, Dong, De‐Mei, Hu, Heng‐Rui, Liu, Ya‐Jie, Fu, Dao‐Xing, He, Yan‐Lin, Zhou, Dong‐Bo, Yang, Hui‐Chuan, Jia, Rui, Ke, Chang‐Wen, Du, Tao, Xie, Yong, Zhou, Rong, Li, Ce‐Sheng, Wang, Man‐Li, Yang, Xiao‐Ming“…COVID‐HIG shows high‐affinity binding to severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) spike (S) protein, the receptor‐binding domain (RBD), the N‐terminal domain of the S protein, and the nucleocapsid protein; and blocks RBD binding to human angiotensin‐converting enzyme 2 (hACE2). …”
Publicado 2022
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3684por Shanmugaraj, Balamurugan, Khorattanakulchai, Narach, Panapitakkul, Chalisa, Malla, Ashwini, Im-erbsin, Rawiwan, Inthawong, Manutsanun, Sunyakumthorn, Piyanate, Hunsawong, Taweewun, Klungthong, Chonticha, Reed, Matthew C., Kemthong, Taratorn, Suttisan, Nutchanat, Malaivijitnond, Suchinda, Srimangkornkaew, Passaraporn, Klinkhamhom, Aekkarin, Manopwisedjaroen, Suwimon, Thitithanyanont, Arunee, Taychakhoonavudh, Suthira, Phoolcharoen, Waranyoo“…Previously, we showed that a protein subunit vaccine that was developed based on the fusion of the SARS-CoV-2 receptor-binding domain (RBD) to the Fc portion of human IgG1 (RBD-Fc), produced in Nicotiana benthamiana, and adjuvanted with alum, namely, Baiya SARS-CoV-2 Vax 1, induced potent immunological responses in both mice and cynomolgus monkeys. …”
Publicado 2022
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3685por Tamura, Miku, Fujita, Retsu, Sato, Tomoaki, Sato, Ryohei, Kato, Yasuyuki, Nagasawa, Mitsuaki, Matsumoto, Tetsuya“…RESULTS: The baseline (before the third dose of BNT162b2) anti-receptor binding domain (RBD) IgG level was 569[377–943] AU/mL 245[240–250] days after the second dose. …”
Publicado 2022
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3686por Wang, Siling, Wu, Yangling, Wang, Yizhen, Chen, Zihao, Ying, Dong, Lin, Xue, Liu, Chang, Lin, Min, Zhang, Jinlei, Zhu, Yuhe, Guo, Shaoqi, Shang, Huixian, Chen, Xiuting, Qiang, Hongsheng, Yin, Yifan, Tang, Zimin, Zheng, Zizheng, Xia, Ningshao“…By utilizing cross-blocking data, we clustered SARS-CoV-2 receptor binding domain (RBD)-specific monoclonal antibodies (mAbs) into 6 clusters. …”
Publicado 2022
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3687por Olearo, Flaminia, Radmanesh, Laura-Sophie, Felber, Nadine, von Possel, Ronald, Emmerich, Petra, Pekarek, Neele, Pfefferle, Susanne, Nörz, Dominik, Hansen, Gudula, Diemert, Anke, Aepfelbacher, Martin, Hecher, Kurt, Lütgehetmann, Marc, Arck, Petra Clara, Tallarek, Ann-Christin“…We conducted a prospective study in which we evaluated concentrations of anti-SARS-CoV-2 Spike IgA and RBD IgG/M/A antibodies in maternal serum and breast milk over a duration of up to 6 months after delivery. …”
Publicado 2022
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3688por Newman, Joseph, Thakur, Nazia, Peacock, Thomas P., Bialy, Dagmara, Elrefaey, Ahmed M. E., Bogaardt, Carlijn, Horton, Daniel L., Ho, Sammy, Kankeyan, Thivya, Carr, Christine, Hoschler, Katja, Barclay, Wendy S., Amirthalingam, Gayatri, Brown, Kevin E., Charleston, Bryan, Bailey, Dalan“…By combining pseudotype neutralization with specific receptor-binding domain (RBD) enzyme-linked immunosorbent assays, we showed that changes to position 484 in the spike RBD were mainly responsible for SARS-CoV-2 neutralizing antibody escape. …”
Publicado 2022
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3689por Abomughaid, Mosleh M., Nofal, Mohammed S., Ghaleb, Khaled I., Seadawy, Mohamed G., AbdEl-Wahab, Miral G., Hegazy, Alaa S., Ghareeb, Doaa A.“…The inhibitory concentration 50 (IC(50)) of ZnO /CGA-NPs against RBD, angiotensin-converting enzyme 2 (ACE2) and PL(pro) were 1647.7, 323.3 µg/mL and 38.7 µg/mL, respectively. …”
Publicado 2022
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3690por Gallichotte, Emily N., Nehring, Mary, Stromberg, Sophia, Young, Michael C., Snell, Ashley, Daniels, Josh, Pabilonia, Kristy L., VandeWoude, Sue, Ehrhart, Nicole, Ebel, Gregory D.“…We observed a strong relationship between neutralizing antibodies and RBD-binding antibodies postvaccination across all groups, whereas no relationship was observed between NP-binding and neutralizing antibodies. …”
Publicado 2022
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3691por Frigerio, Rachele, Marusic, Carla, Villani, Maria Elena, Lico, Chiara, Capodicasa, Cristina, Andreano, Emanuele, Paciello, Ida, Rappuoli, Rino, Salzano, Anna Maria, Scaloni, Andrea, Baschieri, Selene, Donini, Marcello“…In the present work, we describe the production of two SARS-CoV-2 human IgG1 monoclonal antibodies recognizing the spike protein receptor-binding domain (RBD) and endowed with neutralizing activity (nAbs) in plants. …”
Publicado 2022
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3692por Keuning, Maya W., Grobben, Marloes, Bijlsma, Merijn W., Anker, Beau, Berman-de Jong, Eveline P., Cohen, Sophie, Felderhof, Mariet, de Groen, Anne-Elise, de Groof, Femke, Rijpert, Maarten, van Eijk, Hetty W. M., Tejjani, Khadija, van Rijswijk, Jacqueline, Steenhuis, Maurice, Rispens, Theo, Plötz, Frans B., van Gils, Marit J., Pajkrt, Dasja“…Moreover, immunocompromised children showed lower odds for S- and RBD-specific IgG in both serum and saliva compared to healthy children (aOR 0.23 – 0.25, P ≤ 0.050). …”
Publicado 2022
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3693por Ruiz, Maria Julia, Siracusano, Gabriel, Cottignies-Calamarte, Andréa, Tudor, Daniela, Real, Fernando, Zhu, Aiwei, Pastori, Claudia, Capron, Claude, Rosenberg, Arielle R., Temperton, Nigel, Cantoni, Diego, Liao, Hanqing, Ternette, Nicola, Moine, Pierre, Godement, Mathieu, Geri, Guillaume, Chiche, Jean-Daniel, Annane, Djillali, Cramer Bordé, Elisabeth, Lopalco, Lucia, Bomsel, Morgane“…BAL IgG and IgA recognized the four main RBD variants. BAL neutralizing titers were higher early in COVID-19 when virus replicates in the lung than later in infection after viral clearance. …”
Publicado 2022
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3694por Diamantopoulos, Panagiotis T., Kontandreopoulou, Christina-Nefeli, Stafylidis, Christos, Vlachopoulou, Dimitra, Giannakopoulou, Nefeli, Vardaka, Maria, Mpouhla, Anthi, Variami, Eleni, Galanopoulos, Athanasios, Pappa, Vassiliki, Psichogiou, Mina, Hatzakis, Angelos, Viniou, Nora-Athina“…Sera were tested before the first, after the second, and before and after the third dose for anti-SARS-CoV-2 receptor binding domain (RBD) spike protein IgG (anti-RBD). Thirty-nine patients with CLL were included in the study. …”
Publicado 2022
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3695por Bhadauria, Dharmendra S., Katiyar, Harshita, Goel, Amit, Tiwari, Prachi, Kishore, Ravi V. Krishna, Aggarwal, Amita, Verma, Alka, Khetan, Dheeraj, Kaul, Anupma, Yachha, Monika, Behera, Manas Ranjan, Yadav, Brijesh, Prasad, Narayan“…The sera were tested for anti-RBD antibody (ARAb) titre and neutralising antibody (NAb). …”
Publicado 2022
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3696por Farroni, Chiara, Aiello, Alessandra, Picchianti-Diamanti, Andrea, Laganà, Bruno, Petruccioli, Elisa, Agrati, Chiara, Garbuglia, Anna Rosa, Meschi, Silvia, Lapa, Daniele, Cuzzi, Gilda, Petrone, Linda, Vanini, Valentina, Salmi, Andrea, Altera, Anna Maria Gerarda, Repele, Federica, Grassi, Germana, Bettini, Aurora, Vita, Serena, Mariano, Andrea, Damiani, Arianna, Infantino, Maria, Grossi, Valentina, Manfredi, Mariangela, Niccoli, Laura, Puro, Vincenzo, Rosa, Roberta Di, Salemi, Simonetta, Sesti, Giorgio, Scolieri, Palma, Bruzzese, Vincenzo, Benucci, Maurizio, Cantini, Fabrizio, Nicastri, Emanuele, Goletti, Delia“…Most patients with RA scored positive for anti-RBD, neutralizing antibody and T-cell responses, although the magnitude was lower than HCWs. …”
Publicado 2022
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3697por Izuddin, Wan Ibrahim, Loh, Teck Chwen, Akit, Henny, Nayan, Nazri, Noor, Ahmadilfitri Md, Foo, Hooi Ling“…This study explored the effects of dietary crude palm oil (CPO), red palm oil (RPO), refined palm oil (RBD), palm kernel oil (PKO) and soybean oil (SBO) in laying hens. …”
Publicado 2022
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3698por Menon, Aparna R., Cherian, Somy, Paul, Aby, Kumar, Kripesh, Ahmed, Sakir, Mehta, Pankti, Musthafa, Shaik, Gayathri, B., Benny, Libin, Shenoy, Padmanabha“…Patients with AIRDs previously infected with COVID-19, who have received at least one dose of AZD1222/ChAdOx1 (n = 200) were included and stratified based on vaccine doses (V), and infection (I) into I + V, I + V + V, V + I, V + V + I. Anti-RBD (receptor binding domain) antibodies were compared across the four groups. …”
Publicado 2022
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3699por Wang, Yanqun, Yan, An, Song, Deyong, Dong, Chuangchuang, Rao, Muding, Gao, Yuanzhu, Qi, Ruxi, Ma, Xiaomin, Wang, Qiaoping, Xu, Hongguang, Liu, Hong, Han, Jing, Duan, Maoqin, Liu, Shuo, Yu, Xiaoping, Zong, Mengqi, Feng, Jianxia, Jiao, Jie, Zhang, Huimin, Li, Min, Yu, Beibei, Wang, Yanxia, Meng, Fanhao, Ni, Xiaodan, Li, Ying, Shen, Zhenduo, Sun, Baiping, Shao, Xin, Zhao, Haifeng, Zhao, Yanyan, Li, Rui, Zhang, Yanan, Du, Guangying, Lu, Jun, You, Chunna, Jiang, Hua, Zhang, Lu, Wang, Lan, Dou, Changlin, Liu, Zheng, Zhao, Jincun“…Here, we report the isolation and analysis of two anti-RBD neutralizing antibodies BA7208 and BA7125 from mice engineered to produce human antibodies. …”
Publicado 2023
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3700por Kharroubi, Ghassen, Cherif, Ines, Ghawar, Wissem, Dhaouadi, Nawel, Yazidi, Rihab, Chaabane, Sana, Snoussi, Mohamed Ali, Salem, Sadok, Ben Hammouda, Wafa, Ben Hammouda, Sonia, Gharbi, Adel, Bel Haj Hmida, Nabil, Rourou, Samia, Dellagi, Koussay, Barbouche, Mohamed-Ridha, Benabdessalem, Chaouki, Ben Ahmed, Melika, Bettaieb, Jihène“…The prevalence of anti-S-RBD and/or anti-N IgG antibodies was 32.9% [28.7–37.4]. …”
Publicado 2023
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