-
3741por Manomaipiboon, Anan, Phumisantiphong, Uraporn, Maneerit, Jakravoot, Chalearmchai, Yupin, Jirawathin, Warissara, Prajongsai, Achiraya, Phankavong, Patchara, Trakarnvanich, Thananda“…METHODS: We measured anti-SARS-CoV-2 anti-spike RBD IgG and neutralising antibody using a surrogate virus neutralising test (sVNT) among adults aged 18–72 years on average of 8.57 weeks (IQR 6.85–8.93) after the first dose of ChAdOx1 nCoV-19 vaccine. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3742por Hoschler, Katja, Ijaz, Samreen, Andrews, Nick, Ho, Sammy, Dicks, Steve, Jegatheesan, Keerthana, Poh, John, Warrener, Lenesha, Kankeyan, Thivya, Baawuah, Frances, Beckmann, Joanne, Okike, Ifeanichukwu O., Ahmad, Shazaad, Garstang, Joanna, Brent, Andrew J., Brent, Bernadette, Aiano, Felicity, Brown, Kevin E., Ramsay, Mary E., Brown, David, Parry, John V., Ladhani, Shamez N., Zambon, Maria“…Oral fluid assays (OF) using spike protein and RBD antigens were also 99% specific and achieved reasonable but lower sensitivity in the target population (78%, 95% CI [68% to 86%] and 53%, 95% CI [43% to 64%], respectively). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3743por Tanunliong, Guadalein, Liu, Aaron, Vijh, Rohit, Pidduck, Tamara, Kustra, Jesse, Márquez, Ana Citlali, Choi, Alexandra, McLennan, Meghan, Hayden, Althea, Kearney, Christy, Gantt, Soren, Krajden, Mel, Morshed, Muhammad, Jassem, Agatha N., Sekirov, Inna“…Health-Canada approved commercial serologic tests and a pan-coronavirus multiplexed immunoassay were used to evaluate antibody levels against the spike protein, nucleocapsid, and receptor binding domain (RBD) of SARS-CoV-2, as well as the spike proteins of HCoV-229E, HCoV-HKU1, HCoV-NL63, and HCoV-OC43. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3744por McGregor, Joey, Hardy, Joshua M., Lay, Chan-Sien, Boo, Irene, Piontek, Michael, Suckow, Manfred, Coulibaly, Fasséli, Poumbourios, Pantelis, Center, Rob J., Drummer, Heidi E.“…Four variants of E2-S virus-like particles (VLPs) were constructed: Δ123-S, RBD-S, Δ123A7-S, and RBDA7-S; in the last two, 7 cysteines were replaced with alanines. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3745por Torres Rives, Bárbara, Zúñiga Rosales, Yaíma, Mataran Valdés, Minerva, Roblejo Balbuena, Hilda, Martínez Téllez, Goitybell, Rodríguez Pérez, Jacqueline, Caridad Marín Padrón, Lilia, Rodríguez Pelier, Cira, Sotomayor Lugo, Francisco, Valdés Zayas, Anet, Carmenate Portilla, Tania, Sánchez Ramírez, Belinda, Carlos Silva Aycaguer, Luis, Portal Miranda, José Angel, Marcheco Teruel, Beatriz“…IgG / RBD titers were positively correlated with the relative frequency of CD4 + CM T memory cells (r = 0.4352, p = 0.0018). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3746por Davidov, Yana, Indenbaum, Victoria, Tsaraf, Keren, Cohen-Ezra, Oranit, Likhter, Mariya, Ben Yakov, Gil, Halperin, Rebecca, Levy, Itzchak, Mor, Orna, Agmon-Levin, Nancy, Afek, Arnon, Rahav, Galia, Lustig, Yaniv, Ben Ari, Ziv“…The geometric mean of anti-RBD IgG levels, NA levels, and T-cell count also increased significantly after the third dose. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3747por Grunau, Brian, Golding, Liam, Prusinkiewicz, Martin A., Asamoah-Boaheng, Michael, Armour, Richard, Marquez, Ana Citlali, Jassem, Agatha N., Barakauskas, Vilte, O’Brien, Sheila F., Drews, Steven J., Haig, Scott, Lavoie, Pascal M., Goldfarb, David M.“…We also compared secondary outcomes of: receptor binding domain (RBD) wild-type antibody concentrations, and inhibition of angiotensin-converting enzyme 2 (ACE-2) binding to spike proteins from the wild-type strain and five Delta-variant lineages. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3748por Kister, Ilya, Patskovsky, Yury, Curtin, Ryan, Pei, Jinglan, Perdomo, Katherine, Rimler, Zoe, Voloshyna, Iryna, Samanovic, Marie I., Cornelius, Amber R., Velmurugu, Yogambigai, Nyovanie, Samantha, Kim, Joseph J., Tardio, Ethan, Bacon, Tamar E., Zhovtis Ryerson, Lana, Raut, Pranil, Pedotti, Rosetta, Hawker, Kathleen, Raposo, Catarina, Priest, Jessica, Cabatingan, Mark, Winger, Ryan C., Mulligan, Mark J., Krogsgaard, Michelle, Silverman, Gregg J.“…METHODS: Patients with MS aged 18 to 60 years were evaluated for anti‐nucleocapsid and anti‐Spike receptor‐binding domain (RBD) antibody with electro‐chemiluminescence immunoassay; antibody responses to Spike protein, RBD, N‐terminal domain with multiepitope bead‐based immunoassays (MBI); live virus immunofluorescence‐based microneutralization assay; T‐cell responses to SARS‐CoV‐2 Spike using TruCulture enzyme‐linked immunosorbent assay (ELISA); and IL‐2 and IFNγ ELISpot assays. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3749por Zhang, Wuji, Chua, Brendon Y., Selva, Kevin J., Kedzierski, Lukasz, Ashhurst, Thomas M., Haycroft, Ebene R., Shoffner-Beck, Suzanne K., Hensen, Luca, Boyd, David F., James, Fiona, Mouhtouris, Effie, Kwong, Jason C., Chua, Kyra Y. L., Drewett, George, Copaescu, Ana, Dobson, Julie E., Rowntree, Louise C., Habel, Jennifer R., Allen, Lilith F., Koay, Hui-Fern, Neil, Jessica A., Gartner, Matthew J., Lee, Christina Y., Andersson, Patiyan, Khan, Sadid F., Blakeway, Luke, Wisniewski, Jessica, McMahon, James H., Vine, Erica E., Cunningham, Anthony L., Audsley, Jennifer, Thevarajan, Irani, Seemann, Torsten, Sherry, Norelle L., Amanat, Fatima, Krammer, Florian, Londrigan, Sarah L., Wakim, Linda M., King, Nicholas J. C., Godfrey, Dale I., Mackay, Laura K., Thomas, Paul G., Nicholson, Suellen, Arnold, Kelly B., Chung, Amy W., Holmes, Natasha E., Smibert, Olivia C., Trubiano, Jason A., Gordon, Claire L., Nguyen, Thi H. O., Kedzierska, Katherine“…SARS-CoV-2-specific IgM, IgG, IgA are detected in respiratory tract and blood, however, receptor-binding domain (RBD)-specific IgM and IgG seroconversion is enhanced in respiratory specimens. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3750por Li, Yuanyuan, Yang, Yan, Zhao, Aonan, Luo, Ningdi, Niu, Mengyue, Kang, Wenyan, Xie, Anmu, Lu, Hong, Chen, Lei, Liu, Jun“…In addition, CX3CL1 and IL-8 levels were higher in iRBD patients than in HCs. CONCLUSION: We showed a correlation between a profile of four peripheral immune biomarkers and PD development and progression. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3751por Lee, I-Jung, Sun, Cheng-Pu, Wu, Ping-Yi, Lan, Yu-Hua, Wang, I-Hsuan, Liu, Wen-Chun, Yuan, Joyce Pei-Yi, Chang, Yu-Wei, Tseng, Sheng-Che, Tsung, Szu-I, Chou, Yu-Chi, Kumari, Monika, Lin, Yin-Shiou, Chen, Hui-Feng, Chen, Tsung-Yen, Lin, Chih-Chao, Chiu, Chi-Wen, Hsieh, Chung-Hsuan, Chuang, Cheng-Ying, Cheng, Chao-Min, Lin, Hsiu-Ting, Chen, Wan-Yu, Hsu, Fu-Fei, Hong, Ming-Hsiang, Liao, Chun-Che, Chang, Chih-Shin, Liang, Jian-Jong, Ma, Hsiu-Hua, Chiang, Ming-Tsai, Liao, Hsin-Ni, Ko, Hui-Ying, Chen, Liang-Yu, Ko, Yi-An, Yu, Pei-Yu, Yang, Tzu-Jing, Chiang, Po-Cheng, Hsu, Shang-Te, Lin, Yi-Ling, Lee, Chong-Chou, Wu, Han-Chung, Tao, Mi-Hua“…METHODS: We report an mRNA-based vaccine using an engineered “hybrid” receptor binding domain (RBD) that contains all 16 point-mutations shown in the currently prevailing Omicron and Delta variants. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3752por Gallais, Floriane, Renaud-Picard, Benjamin, Solis, Morgane, Laugel, Elodie, Soulier, Eric, Caillard, Sophie, Kessler, Romain, Fafi-Kremer, Samira“…RESULTS: After 3 doses, 47/126 (37.3%) COVID-19-naive LTR had positive anti-RBD IgG (responders) and 14/126 (11.1%) had antibody titers above 264 Binding Antibody Units/mL. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3753por Syversen, Silje W., Jyssum, Ingrid, Tveter, Anne T., Tran, Trung T., Sexton, Joseph, Provan, Sella A., Mjaaland, Siri, Warren, David J., Kvien, Tore K., Grødeland, Gunnveig, Nissen‐Meyer, Lise S. H., Ricanek, Petr, Chopra, Adity, Andersson, Ane M., Kro, Grete B., Jahnsen, Jørgen, Munthe, Ludvig A., Haavardsholm, Espen A., Vaage, John T., Lund‐Johansen, Fridtjof, Jørgensen, Kristin K., Goll, Guro L.“…Analyses of antibodies to the receptor‐binding domain (RBD) of the SARS–CoV‐2 spike protein were performed prior to and 2–4 weeks after vaccination. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3754por Xue, Songyi, Wang, Xinling, Wang, Lei, Xu, Wei, Xia, Shuai, Sun, Lujia, Wang, Shaohui, Shen, Ning, Yang, Ziqi, Huang, Bo, Li, Sihao, Cao, Chuanhai, Calcul, Laurent, Sun, Xingmin, Lu, Lu, Cai, Jianfeng, Jiang, Shibo“…The receptor-binding domain (RBD) in S1 subunit and heptad repeat 1 (HR1) domain in S2 subunit of SARS-CoV-2 spike (S) protein are the targets of neutralizing antibodies (nAbs) and pan-coronavirus (CoV) fusion inhibitory peptides, respectively. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3755por Narayanaswamy, Vignesh, Pentecost, Brian T., Telfer, Janice C., Burnside, Amy S., Schneider, Sallie S., Alfandari, Dominique, Baker, Ryan L., Saiju, Aman, Nodiff, Sam, Arcaro, Kathleen F.“…All samples were tested for receptor-binding domain (RBD)-specific immunoglobulin (Ig)A, IgG, and IgM. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3756por Zhu, Zemin, Zhao, Zhijian, Chen, Xun, Chu, Zhou, He, Yi, Tan, Yingzheng, Zhou, Juan, Tang, Caixi“…RESULTS: The COVID-19-type proinflammatory model was successfully constructed, and 1000 ng/mL RBD treatment for 24 h was selected as the condition for the model group for subsequent experiments. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3757por Yang, Xi, Chi, Hang, Wu, Meng, Wang, Zhenshan, Lang, Qiaoli, Han, Qiuxue, Wang, Xinyue, Liu, Xueqin, Li, Yuanguo, Wang, Xiwen, Huang, Nan, Bi, Jinhao, Liang, Hao, Gao, Yuwei, Zhao, Yongkun, Feng, Na, Yang, Songtao, Wang, Tiecheng, Xia, Xianzhu, Ge, Liangpeng“…In this study, we utilized antibody humanized CAMouse(HG) mice to develop a rapid antibody discovery method and examine the antibody repertoire of SARS-CoV-2 RBD-reactive hybridoma cells derived from CAMouse(HG) mice by using high-throughput single-cell V(D)J sequencing analysis. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3758por Ajlan, Aziza A., Ali, Tariq, Aleid, Hassan, Almeshari, Khalid, DeVol, Edward, Alkaff, Morad Ahmed, Fajji, Layal, Alali, Ali, Halabi, Dani, Althuwaidi, Sahar, Alghamdi, Saad, Ullah, Asad, Alrajhi, Abdulrahman, Bzeizi, Khalid, Almaghrabi, Reem, Marquez, Kris Ann Hervera, Elmikkaoui, Bilal, Albogumi, Eid, Aldakhil, Haifa, Al-Awwami, Moheeb, Broering, Dieter C.“…The primary objective of the study is to directly compare the efficacy of two different vaccine platforms in solid organ transplant recipients by measuring of immunoglobulin G (IgG) antibodies against the RBD of the spike protein (anti-RBD) two weeks after first and second doses. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3759por Chatsiricharoenkul, Somruedee, Niyomnaitham, Suvimol, Posen, Harry Joshua, Toh, Zheng Quan, Licciardi, Paul V., Wongprompitak, Patimaporn, Duangchinda, Thaneeya, Pakchotanon, Pattarakul, Chantima, Warangkana, Chokephaibulkit, Kulkanya“…Neutralizing antibody responses against the SARS-CoV-2 ancestral strain were consistent with what was observed for anti-RBD IgG, with lower titers for SARS-CoV-2 variants. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
3760por Becker, Matthias, Cossmann, Anne, Lürken, Karsten, Junker, Daniel, Gruber, Jens, Juengling, Jennifer, Ramos, Gema Morillas, Beigel, Andrea, Wrenger, Eike, Lonnemann, Gerhard, Stankov, Metodi V., Dopfer-Jablonka, Alexandra, Kaiser, Philipp D., Traenkle, Bjoern, Rothbauer, Ulrich, Krause, Gérard, Schneiderhan-Marra, Nicole, Strengert, Monika, Dulovic, Alex, Behrens, Georg M. N.“…After triple BNT162b2 vaccination, anti-RBD B.1 IgG and ACE2 binding inhibition reached peak levels in dialysis patients, but remained inferior compared to controls. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto