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4181por Springer, David Niklas, Traugott, Marianna, Reuberger, Elisabeth, Kothbauer, Klaus Benjamin, Borsodi, Christian, Nägeli, Michelle, Oelschlägel, Theresa, Kelani, Hasan, Lammel, Oliver, Deutsch, Josef, Puchhammer-Stöckl, Elisabeth, Höltl, Eva, Aberle, Judith Helene, Stiasny, Karin, Weseslindtner, Lukas“…Indeed, variant-specific RBD-ACE2 binding inhibition levels significantly correlated with respective NT titers (p < 0.0001, Spearman’s r = 0.92 and r = 0.80 for WT and Omicron, respectively). …”
Publicado 2023
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4182por Skarke, Carsten, Lordan, Ronan, Barekat, Kayla, Naik, Amruta, Mathew, Divij, Ohtani, Takuya, Greenplate, Allison R., Grant, Gregory R., Lahens, Nicholas F., Gouma, Sigrid, Troisi, Elizabeth, Sengupta, Arjun, Weljie, Aalim M., Meng, Wenzhao, Luning Prak, Eline T., Lundgreen, Kendall, Bates, Paul, Meng, Hu, FitzGerald, Garret A.“…A SARS-CoV-2 vaccine–specific receptor binding domain (RBD) IgG antibody response and efficacy in the evoked neutralization titers were evident irrespective of concomitant NSAID consumption. …”
Publicado 2023
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4183por Prayongrat, Anussara, Noppaving, Patjaya, Chobarporn, Thitiporn, Sudhinaraset, Natthinee, Teeyapun, Nattaya, Pakvisal, Nussara, Jantarabenjakul, Watsamon, Sophonphan, Jiratchaya, Lertbutsayanukul, Chawalit, Poovorawan, Yong“…The seroconversion rate and anti-RBD immunoglobulin geometric mean titers (GMT) were assessed and compared with healthy controls. …”
Publicado 2023
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4184por Bakr, Salwa, Ezzat, Eman Mahmoud, Salem, Karem Mohamed, Masoud, Mohamed, Abdelaziz, Hossam Eldin Mahmoud“…METHODS: in this cross-sectional community-based pilot study, immunoglobulin G (IgG) antibodies that are specific for the SARS-CoV-2 spike (S1-RBD) protein were tested during the period from February 2021 to July 2021. …”
Publicado 2023
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4185por Park, Eunyoung, Rawson, Shaun, Schmoker, Anna, Kim, Byeong-Won, Oh, Sehee, Song, Kangkang, Jeon, Hyesung, Eck, Michael J.“…Prior structural studies of KRAS with RAF have focused on the isolated RAS-binding and cysteine-rich domains of RAF (RBD and CRD, respectively), which interact directly with RAS. …”
Publicado 2023
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4186por Zhang, Ju, Zhu, Airu, Mei, Miao, Qu, Jing, Huang, Yalan, Shi, Yongshi, Xue, Meiying, Zhang, Jingfang, Zhang, Renli, Zhou, Bing, Tan, Xu, Zhao, Jincun, Wang, Yu“…Using CRISmers, aptamers are identified specifically targeting the receptor binding domain (RBD) of the spike glycoprotein of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). …”
Publicado 2023
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4187por Meyers, Eline, De Smet, Evelien, Vercruysse, Hanne, Callens, Steven, Padalko, Elizaveta, Heytens, Stefan, Vandekerckhove, Linos, Cools, Piet, Witkowski, Wojciech“…Baseline samples were assessed for serum 25-hydroxyvitamin D levels, while follow-up samples were analyzed for spike protein S1 receptor-binding domain (S1RBD) IgG antibody concentrations and 50% pseudoneutralization titers. …”
Publicado 2023
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4188por Gumanova, Nadezhda G., Gorshkov, Alexander U., Bogdanova, Natalya L., Korolev, Andrei I.“…COVID-19 episodes were confirmed by detection of IgG-SARS against SARS-CoV-2 S1 RBD to reveal 70 IgG-SARS-positive and 237 negative participants. …”
Publicado 2023
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4189por Dickson, Alexandria, Geerling, Elizabeth, Stone, E. Taylor, Hassert, Mariah, Steffen, Tara L., Makkena, Taneesh, Smither, Madeleine, Schwetye, Katherine E., Zhang, Jianfeng, Georges, Bertrand, Roberts, M. Scot, Suschak, John J., Pinto, Amelia K., Brien, James D.“…METHODS: Utilizing a replication-deficient adenovirus serotype 5-vectored vaccine expressing the SARS-CoV-2 RBD (AdCOVID) in homozygous and heterozygous transgenic K18-hACE2, we investigated the impact of the route of administration on vaccine immunogenicity, SARS-CoV-2 transmission, and survival. …”
Publicado 2023
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4190por Ravindran, Resmi, O’Connor, Ellen, Gupta, Ajay, Luciw, Paul A., Khan, Aleena I., Dorreh, Nasrin, Chiang, Kate, Ikram, Aamer, Reddy, Srinivasa“…We investigated 48 plasma cytokines/chemokines, 21 lipid mediators, and anti-S protein (RBD) antibodies in COVID-19 patients (n = 56) and non-COVID-19 respiratory disease controls (n = 49), to identify immune-biomarker profiles. …”
Publicado 2023
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4191por Moatasim, Yassmin, Kutkat, Omnia, Osman, Ahmed M., Gomaa, Mokhtar R., Okda, Faten, El Sayes, Mohamed, Kamel, Mina Nabil, Gaballah, Mohamed, Mostafa, Ahmed, El-Shesheny, Rabeh, Kayali, Ghazi, Ali, Mohamed A., Kandeil, Ahmed“…Furthermore, in silico studies were performed for these promising vitamins to investigate their interaction with SARS-CoV-2, MERS-CoV, and HCoV-229E viral-specific cell receptors (ACE2, DPP4, and hAPN protein, respectively) and viral proteins (S-RBD, 3CL pro, RdRp), suggesting that Hydroxocobalamin, Methylcobalamin, and Cyanocobalamin may have significant binding affinity to these proteins. …”
Publicado 2023
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4192por Lo Presti, Alessandra, Di Martino, Angela, Ambrosio, Luigina, De Sabato, Luca, Knijn, Arnold, Vaccari, Gabriele, Di Bartolo, Ilaria, Morabito, Stefano, Terregino, Calogero, Fusaro, Alice, Monne, Isabella, Giussani, Edoardo, Tramuto, Fabio, Maida, Carmelo Massimo, Mazzucco, Walter, Costantino, Claudio, Rueca, Martina, Giombini, Emanuela, Gruber, Cesare Ernesto Maria, Capobianchi, Maria Rosaria, Palamara, Anna Teresa, Stefanelli, Paola“…Three of the positive sites in the spike were located in the receptor-binding domain (RBD). In Delta genomes from the three regions, 6 changes were identified as very common (>83.7%), 4 as common (>64.0%), 21 at low frequency (2.1%–25.0%) and 29 rare (≤2.0%). …”
Publicado 2023
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4193por Newhouse, E. Irene, Xu, Dong, Markwick, Phineus R. L., Amaro, Rommie E., Pao, Hsing C., Wu, Kevin J., Alam, Maqsudul, McCammon, J. Andrew, Li, Wilfred W.“…On the basis of detailed analyses of the dynamic motions of the receptor binding domains (RBDs) and interaction energy profiles with individual glycan residues, we have identified ∼30 residue positions in the RBD that present distinct profiles with the receptor analogues. …”
Publicado 2009
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4194por Prabakaran, Ponraj, Zhu, Zhongyu, Chen, Weizao, Gong, Rui, Feng, Yang, Streaker, Emily, Dimitrov, Dimiter S.“…To further explore our hypothesis, we used the 454 sequence analysis of a large naïve library of human IgM antibodies which had been used for selecting antibodies against SARS CoV receptor-binding domain (RBD), and soluble G proteins (sG) of henipaviruses. …”
Publicado 2012
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4195por Gil-Humanes, Javier, Pistón, Fernando, Giménez, María J., Martín, Antonio, Barro, Francisco“…In addition, a positive effect was observed in the MT, PR1 and RBD in some of the transgenic lines of ‘Podenco’ and ‘Arpain’. …”
Publicado 2012
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4196“…Regulation of αMβ2 function occurs through the R333 residue of the RGS14 Ras/Rap binding domain (RBD) and the F754 residue of β2, residues previously shown to be involved in binding of H-Ras and talin1 head binding prior to αMβ2 activation, respectively. …”
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4197por Upadhyay, Santosh Kumar, Dixit, Sameer, Sharma, Shailesh, Singh, Harpal, Kumar, Jitesh, Verma, Praveen C., Chandrashekar, K.“…We found helicase, PAZ, RNaseIIIa, RNaseIIIb and double-stranded RNA-binding fold (DSRBF) in Dicer2; DsRBD in R2D2; and PAZ and PIWI domains in Argonaute2. …”
Publicado 2013
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4198“…Certain transposons display a preference for either dsRBD-protein during production or loading; this appeared to correlate neither with overall abundance, classification of the transposon or a specific site of genomic origin. …”
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4199“…To overcome this host defense mechanism, many poxviruses express the protein E3L, containing an N-terminal Z-DNA binding (Zα) domain and a C-terminal dsRNA-binding domain (dsRBD). While E3L is thought to inhibit PKR activation by sequestering dsRNA activators and by directly binding the kinase, the role of the Zα domain in PKR inhibition remains unclear. …”
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4200“…With BiFC-PALM, we studied the interactions between the small GTPase Ras and its downstream effector Raf, and clearly observed nanoscale clustering and diffusion of individual KRas G12D/CRaf RBD (Ras-binding domain) complexes on the cell membrane. …”
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