-
4661por Zhao, Zhennan, Xie, Yufeng, Bai, Bin, Luo, Chunliang, Zhou, Jingya, Li, Weiwei, Meng, Yumin, Li, Linjie, Li, Dedong, Li, Xiaomei, Li, Xiaoxiong, Wang, Xiaoyun, Sun, Junqing, Xu, Zepeng, Sun, Yeping, Zhang, Wei, Fan, Zheng, Zhao, Xin, Wu, Linhuan, Ma, Juncai, Li, Odel Y., Shang, Guijun, Chai, Yan, Liu, Kefang, Wang, Peiyi, Gao, George F., Qi, Jianxun“…Structures of S/hACE2 or RBD/hACE2 complexes for these sub-variants and BA.2 S binding to ACE2 of mouse, rat or golden hamster are determined to reveal the molecular basis for receptor binding and broader interspecies recognition.…”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4662por Barrios, Marilou H., Nicholson, Suellen, Bull, Rowena A., Martinello, Marianne, Rawlinson, William, Mina, Michael, Post, Jeffrey J., Hudson, Bernard, Gilroy, Nicole, Lloyd, Andrew R., Konecny, Pamela, Mordant, Francesca, Catton, Mike, Subbarao, Kanta, Caly, Leon, Druce, Julian, Netter, Hans J.“…The test targeted the four major structural proteins of SARS-CoV-2, namely the nucleocapsid (N), spike (S) protein domains S1 and S2, and receptor-binding domain (RBD). Serum samples were collected from 63 participants at various time points for up to 300 days after disease onset. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4663por Samoud, Samar, Bettaieb, Jihene, Gdoura, Mariem, Kharroubi, Ghassen, Ben Ghachem, Feriel, Zamali, Imen, Ben Hmid, Ahlem, Salem, Sadok, Gereisha, Ahmed Adel, Dellagi, Mongi, Hogga, Nahed, Gharbi, Adel, Baccouche, Amor, Gharbi, Manel, Khemissi, Chadha, Akili, Ghada, Slama, Wissem, Chaieb, Nabila, Galai, Yousr, Louzir, Hechmi, Triki, Henda, Ben Ahmed, Melika“…(1) Background: This study aimed to compare the immunogenicity of the mix-and-match CoronaVac/BNT162b2 vaccination to the homologous CoronaVac/CoronaVac regimen. (2) Methods: We conducted a simple-blinded randomized superiority trial to measure SARS-CoV-2 neutralization antibodies and anti-spike receptor binding domain (RBD) IgG concentrations in blood samples of participants who had received the first dose of CoronaVac vaccine followed by a dose of BNT162b2 or CoronaVac vaccine. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4664por Garg, Nidhi, Kunamneni, Ananya Sree, Garg, Pankaj, Sharma, Sandeep, Sharma, Divakar, Kunamneni, Adinarayana“…The Omicron variant of concern (VOC) replaced the delta variant rapidly and became the predominant strain due to more mutations in spike protein and receptor-binding domain (RBD) enhancing its infectivity and binding affinity. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4665por Li, Yizhe, He, Jinyong, Zhang, Ying, Liang, Dan, Zhang, Jiaqi, Ji, Ruili, Wu, Yue, Su, Zejie, Ke, Changwen, Xu, Ning, Tang, Yong, Xu, Jianhua“…METHODS: This assay utilizes the characteristic that SARS-CoV-2 neutralizing antibody can specifically block the binding of the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein and angiotensin-converting enzyme 2 (ACE2) to rapidly detect the content of neutralizing antibody in COVID-19-infected patients and vaccine recipients. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4666por Pérez-Juárez, Horacio, Serrano-Vázquez, Angélica, Godínez-Alvarez, Héctor, González, Enrique, Rojas-Velázquez, Liliana, Moran, Patricia, Portillo-Bobadilla, Tobías, Ramiro, Manuel, Hernández, Eric, Lau, Clara, Martínez, Marcela, Padilla, Ma. de los Ángeles, Zaragoza, Martha E., Taboada, Blanca, Palomares, Laura A., López, Susana, Alagón, Alejandro, Arias, Carlos F., Ximénez, Cecilia“…Seropositivity of volunteers from Mexico City and the State of Mexico, Mexico, was evaluated by ELISA using the recombinant receptor-binding domain (RBD) of the SARS-CoV-2 Spike protein for 90 days, at different time points (1, 15, 45, 60, and 90 days) after molecular diagnosis (RT-qPCR). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4667por Norton, Natasha J., Ings, Danielle P., Fifield, Kathleen E., Barnes, David A., Barnable, Keeley A., Harnum, Debbie O. A., Holder, Kayla A., Russell, Rodney S., Grant, Michael D.“…Subjects with higher levels of vaccine-induced IgA against SARS-CoV-2 S (p = 0.0333) or receptor binding domain (RBD) (p = 0.0266) were less likely to experience an Omicron breakthrough infection. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4668por Nagasawa, Norika, Kimura, Ryusuke, Akagawa, Mao, Shirai, Tatsuya, Sada, Mitsuru, Okayama, Kaori, Sato-Fujimoto, Yuka, Saito, Makoto, Kondo, Mayumi, Katayama, Kazuhiko, Ryo, Akihide, Kuroda, Makoto, Kimura, Hirokazu“…Selective pressure analysis estimated that the prevalent subvariants, XBB.1.5 and XBB.1.16, had specific amino acid mutations, such as V445P, G446S, N460K, and F486P, located in the RBD when compared with the BA.4 and BA.5 subvariants. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4669por Hutchinson, Geoffrey B., Abiona, Olubukola M., Ziwawo, Cynthia T., Werner, Anne P., Ellis, Daniel, Tsybovsky, Yaroslav, Leist, Sarah R., Palandjian, Charis, West, Ande, Fritch, Ethan J., Wang, Nianshuang, Wrapp, Daniel, Boyoglu-Barnum, Seyhan, Ueda, George, Baker, David, Kanekiyo, Masaru, McLellan, Jason S., Baric, Ralph S., King, Neil P., Graham, Barney S., Corbett-Helaire, Kizzmekia S.“…However, targeting conserved non-RBD epitopes could limit the potential for antigenic escape. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4670por Kared, Hassen, Alirezaylavasani, Amin, Lund, Katrine Persgård, Chopra, Adity, Tietze, Lisa, de Matos Kasahara, Taissa, Goll, Guro Løvik, Grødeland, Gunnveig, Kaarbø, Mari, Reisæter, Anna Varberg, Hovd, Markus, Heldal, Kristian, Vaage, John Torgils, Lund-Johansen, Fridtjof, Midtvedt, Karsten, Åsberg, Anders, Munthe, Ludvig A.“…METHODS: We conducted a serologically guided interventional study where KTR patients that failed to seroconvert were revaccinated and also monitored seroconversion of KTR following the Norwegian vaccination program. We analysed IgG anti-RBD Spike responses from dose 2 (n = 432) up to after the 6th (n = 37) mRNA vaccine dose. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4671por Rottmayer, Karla, Loeffler-Wirth, Henry, Gruenewald, Thomas, Doxiadis, Ilias, Lehmann, Claudia“…Here, we investigated the humoral immune response against SARS-CoV-2 spike, S1, S2, the RBD, nucleocapsid moieties and S1 of seasonal coronaviruses: hCoV-229E, hCoV-HKU1, hCoV-NL63 and hCoV-OC43, as well as MERS-CoV and SARS-CoV, in a cohort of 512 individuals. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4672por Joo, Yoosun, Kim, Dae Kyu, Jeon, Yun Gi, Kim, Ah-Ra, Do, Hyeon Nam, Yoon, Soo-Young, Kim, Jin Sug, Jung, Su Woong, Hwang, Hyeon Seok, Moon, Ju-Young, Jeong, Kyung Hwang, Lee, Sang-Ho, Kang, So-Young, Kim, Yang Gyun“…Humoral response to vaccination was measured by quantifying immunoglobulin G levels against the receptor binding domain of SARS-CoV-2 (anti-RBD IgG) at five different times and plaque reduction neutralization tests (PRNT) at two different times after vaccination over a period of 18 months. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4673por Najafi, Niloofar, Soleimanjahi, Hoorieh, Moghaddam-Banaem, Lida, Raoufy, Mohammad Reza, Shahali, Shadab, Kazemnejad, Anoshirvan, Nasiri, Zeynab“…Anti-SARS-CoV-2 receptor-binding domain [RBD] IgG titer was compared in 3 groups, each vaccinated by available vaccines in Iran at the time: Oxford/AstraZeneca, COVIran Barekat, and Sinopharm. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4674por Souza, Hellen Cris Araújo, Souza, Maycon Douglas Araújo, Sousa, Cássio Silva, Viana, Edilanne Katrine Amparo, Alves, Sabrina Kelly Silva, Marques, Alex Oliveira, Ribeiro, Arthur Serejo Neves, de Sousa do Vale, Vanessa, Islam, Muhammad Torequl, de Miranda, João Antônio Leal, da Costa Mota, Marcelo, Rocha, Jefferson Almeida“…Therefore, this study aimed to identify potential antiviral compounds from a popular medicinal plant called Moringa oleifera Lam. against the spike, M(pro), ACE2, and RBD targets of SARS-CoV-2. For this, we use molecular docking to identify the molecules with the greatest affinity for the targets through the orientation of the ligand with the receptor in complex. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4675por Ma, Ying, Lei, Mengyue, Chen, Hongli, Huang, Pu, Sun, Jing, Sun, Qiangming, Hu, Yunzhang, Shi, Jiandong“…The residues interfacing with the N-terminal domain (NTD) or receptor-binding domain (RBD) of S were aligned to screen the critical aa sites that determined the susceptibility of the SARS-CoV-2 to the host. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4676por Marrocco, Katia, Criqui, Marie-Claire, Zervudacki, Jérôme, Schott, Gregory, Eisler, Herfried, Parnet, Aude, Dunoyer, Patrice, Genschik, Pascal“…Moreover, APC10 interacts with DRB4 through the second dsRNA binding motif (dsRBD2) of DRB4, which is also required for its homodimerization and binding to its Dicer partner DCL4. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4677por Zhao, Guangyu, Du, Lanying, Ma, Cuiqing, Li, Ye, Li, Lin, Poon, Vincent KM, Wang, Lili, Yu, Fei, Zheng, Bo-Jian, Jiang, Shibo, Zhou, Yusen“…Consistent with the results from a live MERS-CoV-based inhibition assay, the antisera of mice vaccinated with a recombinant protein containing receptor-binding domain (RBD, residues 377–662) of MERS-CoV S fused with Fc of human IgG exhibited neutralizing antibody response against infection of MERS-CoV pseudovirus. …”
Publicado 2013
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4678por de Queiroz, Camila AA, Fonseca, Said Gonçalves C, Frota, Priscila B, Figueiredo, Ítalo L, Aragão, Karoline S, Magalhães, Carlos Emanuel C, de Carvalho, Cibele BM, Lima, Aldo Ângelo M, Ribeiro, Ronaldo A, Guerrant, Richard L, Moore, Sean R, Oriá, Reinaldo B“…METHODS: Rats were undernourished using a northeastern Brazil regional diet (RBD) for two weeks, followed by oral gavage with a saturated lactose solution (30 g/kg) in the last 7 days to induce osmotic diarrhea. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4679“…CONCLUSIONS: Biodiesel production with filtered, degummed, low FFA Jatropha oil using a free liquid lipase (TL) as catalyst showed higher yielding potential than immobilized CA lipase as substitute of RBD palm oil with alkaline catalyst. However, Jatropha enzymatic biodiesel yield and stability were inferior to alkaline catalyzed biodiesel and not in compliance with international quality standards. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
4680por Oliver, María D., Fernández-Acero, Teresa, Luna, Sandra, Rodríguez-Escudero, Isabel, Molina, María, Pulido, Rafael, Cid, Víctor J.“…The activity of p110α in yeast was not compromised by truncation of its N-terminal adaptor-binding domain (ABD) or inactivation of the Ras-binding domain (RBD). In contrast, a cluster of positively charged residues at the C2 domain was essential. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto