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  1. 4981
    “…In this study, we evaluated the effectiveness of a synthetic peptide cocktail containing three murine CD4(+) T-cell epitopes from the SARS-CoV-2 nonspike proteome and one B-cell epitope from the Omicron BA.1 receptor-binding domain (RBD), along with aluminum phosphate (Al) adjuvant and 5′ cytosine-phosphate-guanine 3′ oligodeoxynucleotide (CpG-ODN) adjuvant in mice. …”
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    A Synthetic SARS-CoV-2-Derived T-Cell and B-Cell Peptide Cocktail Elicits Full Protection against Lethal Omicron BA.1 Infection in H11-K18-hACE2 Mice
  2. 4982
    “…Both formulations demonstrated the presence of anti-RBD antibodies in the plasma of immunized mice, being significantly higher for the latter adjuvant. …”
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    A COVID-19 vaccine candidate based on SARS-CoV-2 spike protein and immune-stimulating complexes
  3. 4983
    “…An automated chemiluminescence immune assay (CLIA) platform from Abbott Diagnostics was used to quantify IgG antibodies against SARS-CoV-2′s spike receptor-binding domain (RBD) and a surrogate virus neutralization test (sVNT) was performed by enzyme-linked immunosorbent assay (ELISA). …”
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    PERSISTENCE AND DYNAMICITY OF SARS-COV-2 ANTIBODY RESPONSE AFTER DOUBLE DOSE OF BBV-152 AND AZD1222 VACCINES: A PROSPECTIVE, LONGITUDINAL, YEAR-LONG COHORT STUDY
  4. 4984
    “…Serum samples were collected and tested for SARS-CoV-2 S-receptor-binding domain (S-RBD) immunoglobulin G (IgG) at enrollment. Data on adverse events (AEs) within 7 days after the second dose were obtained using a questionnaire. …”
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    Antibody response and safety of inactivated SARS-CoV-2 vaccines in chronic hepatitis B patients with and without cirrhosis
  5. 4985
    “…While extensive research on the role of the Receptor Binding Domain (RBD) in promoting viral infectivity and vaccine sensitivity has been well documented, the functional significance of the (681)PRRAR/SV(687) polybasic motif of the viral spike is less clear. …”
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    Changes within the P681 residue of spike dictate cell fusion and syncytia formation of Delta and Omicron variants of SARS-CoV-2 with no effects on neutralization or infectivity
  6. 4986
    por Benkeser, David, Montefiori, David C., McDermott, Adrian B., Fong, Youyi, Janes, Holly E., Deng, Weiping, Zhou, Honghong, Houchens, Christopher R., Martins, Karen, Jayashankar, Lakshmi, Castellino, Flora, Flach, Britta, Lin, Bob C., O’Connell, Sarah, McDanal, Charlene, Eaton, Amanda, Sarzotti-Kelsoe, Marcella, Lu, Yiwen, Yu, Chenchen, Borate, Bhavesh, van der Laan, Lars W. P., Hejazi, Nima S., Kenny, Avi, Carone, Marco, Williamson, Brian D., Garver, Jennifer, Altonen, Erin, Rudge, Thomas, Huynh, Chuong, Miller, Jacqueline, El Sahly, Hana M., Baden, Lindsey R., Frey, Sharon, Malkin, Elissa, Spector, Stephen A., Andrasik, Michele P., Kublin, James G., Corey, Lawrence, Neuzil, Kathleen M., Carpp, Lindsay N., Pajon, Rolando, Follmann, Dean, Donis, Ruben O., Koup, Richard A., Gilbert, Peter B.
    Publicado 2023
    “…We previously assessed IgG binding antibodies to the spike protein (spike IgG) or receptor binding domain (RBD IgG) and pseudovirus neutralizing antibody 50 or 80% inhibitory dilution titer measured on day 29 or day 57, as correlates of risk (CoRs) and CoPs against symptomatic COVID-19 over 4 months after dose. …”
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    Comparing antibody assays as correlates of protection against COVID-19 in the COVE mRNA-1273 vaccine efficacy trial
  7. 4987
    por Marcinkevics, Ricards, Silva, Pamuditha N., Hankele, Anna-Katharina, Dörnte, Charlyn, Kadelka, Sarah, Csik, Katharina, Godbersen, Svenja, Goga, Algera, Hasenöhrl, Lynn, Hirschi, Pascale, Kabakci, Hasan, LaPierre, Mary P., Mayrhofer, Johanna, Title, Alexandra C., Shu, Xuan, Baiioud, Nouell, Bernal, Sandra, Dassisti, Laura, Saenz-de-Juano, Mara D., Schmidhauser, Meret, Silvestrelli, Giulia, Ulbrich, Simon Z., Ulbrich, Thea J., Wyss, Tamara, Stekhoven, Daniel J., Al-Quaddoomi, Faisal S., Yu, Shuqing, Binder, Mascha, Schultheiβ, Christoph, Zindel, Claudia, Kolling, Christoph, Goldhahn, Jörg, Seighalani, Bahram Kasmapour, Zjablovskaja, Polina, Hardung, Frank, Schuster, Marc, Richter, Anne, Huang, Yi-Ju, Lauer, Gereon, Baurmann, Herrad, Low, Jun Siong, Vaqueirinho, Daniela, Jovic, Sandra, Piccoli, Luca, Ciesek, Sandra, Vogt, Julia E., Sallusto, Federica, Stoffel, Markus, Ulbrich, Susanne E.
    Publicado 2023
    “…By using statistical and machine learning models, we observed that the T cell response highly correlated with a compound titer of antibodies against the Receptor Binding Domain (RBD), S and N. However, while serum antibodies decayed over time, the cellular phenotype of these individuals remained stable over four months. …”
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    Machine learning analysis of humoral and cellular responses to SARS-CoV-2 infection in young adults
  8. 4988
    “…Monthly quantitative antibody testing was performed using the Beckman Coulter Access SARS-CoV-2 IgG Antibody Test©, which detects IgG antibodies targeting the receptor binding domain (RBD) of the SARS-CoV-2 spike protein. Results: This cohort of 30 participants (mean age: 61 ± 3 years) predominantly self-identified as African American (97%) and male (53%). …”
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    COVID-19 Vaccine Antibody Response in a Single-Center Urban Hemodialysis Unit
  9. 4989
    “…SARS-CoV-2 antibodies against the subunit 1 (S1) and receptor binding domain (RBD) protein were detected in 2.7% (95% CI 1.4–4.8) of stray cats, but sera were negative in the pseudovirus neutralization test and therefore were considered SARS-CoV-2 suspected. …”
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    Serological Survey of Retrovirus and Coronavirus Infections, including SARS-CoV-2, in Rural Stray Cats in The Netherlands, 2020–2022
  10. 4990
    “…Ad5-nCoV elicits significantly higher RBD-specific IgG levels, with a geometric mean concentration of 2924.0 on day 14 post-booster, 7.8-fold that of the inactivated vaccine. …”
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    Safety and immunogenicity of Ad5-nCoV immunization after three-dose priming with inactivated SARS-CoV-2 vaccine in Chinese adults
  11. 4991
    “…Here, we examined, in two ambispective cohorts of naturally-infected and/or vaccinated individuals, the titers of anti-RBD antibodies and the frequency of SARS-CoV-2-specific CD4(+) T cells up to 6 months after the last antigen exposure. …”
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    Cross-reactive humoral and CD4(+) T cell responses to Mu and Gamma SARS-CoV-2 variants in a Colombian population
  12. 4992
    “…The non-synonymous iSNVs in the S gene can largely alter the S protein’s antigenic features, and many of these iSNVs are distributed in the amino-terminal domain (NTD) and receptor-binding domain (RBD). These results suggest that SARS-CoV-2 interacts actively with human hosts and attempts to take different evolutionary strategies to escape human innate and adaptive immunity. …”
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    SARS-CoV-2 within-host diversity of human hosts and its implications for viral immune evasion
  13. 4993
    “…Consensus (>50% frequency) spike mutations were identified in 5 individuals who were rRT-PCR-positive >56 days; 61% were in the receptor-binding domain (RBD). Mutations shared by multiple individuals were rare (<5%) in global circulation. …”
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    SARS-CoV-2 shedding and evolution in immunocompromised hosts during the Omicron period: a multicenter prospective analysis
  14. 4994
    “…In unvaccinated convalescent participants, a receptor binding domain (RBD) IgG of 456 BAU/mL predicts an NT50 against WT of 1000 IU with an accuracy of 80% (95%CI 73–86%). …”
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    Distinct receptor binding domain IgG thresholds predict protective host immunity across SARS-CoV-2 variants and time
  15. 4995
    por Li, Ying, Lynch, William P
    Publicado 2010
    “…However, CasBrE SU synthesized in the absence of the transmembrane subunit (TM) does not retain ecotropic receptor binding activity, indicating that folding of the receptor binding domain (RBD) requires this domain. Using a neural stem cell (NSC) based viral trans complementation approach to examine whether misfolded CasBrE SU retained neurovirulence, we observed CasBrE SU interaction with the "non-neurovirulent" amphotropic helper virus, 4070A which restored functional activity of CasBrE SU. …”
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    Misfolding of CasBrE SU is reversed by interactions with 4070A Env: implications for gammaretroviral neuropathogenesis
  16. 4996
    “…A representative 3D models for each of the RBD domain identified in P. falciparum was created using I-TESSAR and SWISS-MODEL. …”
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    A bioinformatic survey of RNA-binding proteins in Plasmodium
  17. 4997
    por Yu, Jiu-wang, Wang, Lu, Bao, Li-dao
    Publicado 2020
    “…In view of the high homology of gene sequences between SARS-CoV-2 S-protein RBD domain and SARS virus, as well as their similarities in pathogenesis and clinical manifestations, we established SARS-CoV-2 S-protein model using Swiss-Model. …”
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    Exploring the active compounds of traditional Mongolian medicine in intervention of novel coronavirus (COVID-19) based on molecular docking method
  18. 4998
    “…Five treatments viz., T(1); N(0)P(0)K(0); T(2): N(75)P(13)K(25); T(3): N(150)P(26)K(50); T(4): N(75)P(13)K(25) + microbial consortium and T(5): N(150)P(26)K(50) + microbial consortium containing new strains of Trichoderma harzianum, Gluconcetobacter diazotrophicus, and Pseudomonas fluorescens (CFU 10(9–10) per ml liquid culture) were evaluated under four replications in a randomized block design (RBD). Experimental results indicated that integrating microbial consortium and NPK fertilizers' application proved effective in improving soil organic carbon, soil microbial population, microbial biomass carbon, microbial biomass nitrogen, and soil respiration. …”
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    Soil quality parameters vis-a-vis growth and yield attributes of sugarcane as influenced by integration of microbial consortium with NPK fertilizers
  19. 4999
    “…All patients had detectable antibodies to the receptor binding domain (RBD), and 95% of these patients had IgG to viral N proteins. …”
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    Kinetic changes in virology, specific antibody response and imaging during the clinical course of COVID-19: a descriptive study
  20. 5000
    “…METHODS: Serology assays from Roche, Abbott, Diasorin, BioMerieux, Beckman-Coulter, Siemens, and an in-house RBD ELISA were included. Negative samples from 2391 individuals representative of the Israeli population, and 698 SARS-CoV-2 PCR positive patients, collected between March and May 2020, were analyzed FINDINGS: Immunoassays sensitivities between 81.5%-89.4% and specificities between 97.7%-100% resulted in a profound impact on the expected Positive Predictive Value (PPV) in low (<15%) prevalence scenarios. …”
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    Multi-center nationwide comparison of seven serology assays reveals a SARS-CoV-2 non-responding seronegative subpopulation
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