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  1. 5101
    “…We found a 12.3- to 16.1-fold increase in antibodies targeting the receptor binding domain (RBD) of the Delta variant with 2× MVC/Mod compared to two doses of MVC (2× MVC) or AZD1222 (2× AZ) regimens and a 26- to 32.2-fold improvement in neutralizing potency against the Omicron variant (BA.1). …”
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    Boosting with Multiple Doses of mRNA Vaccine after Priming with Two Doses of Protein Subunit Vaccine MVC-COV1901 Elicited Robust Humoral and Cellular Immune Responses against Emerging SARS-CoV-2 Variants
  2. 5102
    “…Two of 18 (11.1%) and 8 of 16 (50.0%) patients with an anti-S1-RBD IgG of 100–1411 and > 1411 BAU/mL, respectively, showed a neutralization activity against the omicron variant. …”
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    Humoral immune response and live-virus neutralization of the SARS-CoV-2 omicron (BA.1) variant after COVID-19 mRNA vaccination in children and young adults with chronic kidney disease
  3. 5103
    “…We aimed at assessing agreement with three serological tests: quantitative anti receptor binding domain ELISA (Q-RBD), qualitative ELISA (WANTAI SARS-CoV-2 Ab) and qualitative chemiluminescence assay (CLIA). …”
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    Test concordance and diagnostic accuracy of three serological assays for detection of anti-SARS-CoV-2 antibody: result from a population-based sero-epidemiological study in Delhi
  4. 5104
    “…The EUROIMMUN ELISA using spike 1 as the antigen detected more positives among the primary DENV infections than the in-house ELISA using spike 1-receptor binding domain (RBD) protein. Among ELISA-positive samples, four had detectable neutralizing antibodies against SARS-CoV-2 reporter virus particles yet none had detectable neutralizing antibodies against the live Wuhan strain of SARS-CoV-2. …”
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    Anti-Arbovirus Antibodies Cross-React With Severe Acute Respiratory Syndrome Coronavirus 2
  5. 5105
    “…In addition, we observed increased binding of spike receptor-binding domain (RBD) protein to Huh7.5(HCV) cells, as well as enhanced cell-to-cell fusion of Huh7.5(HCV) cells with spike-expressing Huh7.5 cells. …”
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    HCV Infection Increases the Expression of ACE2 Receptor, Leading to Enhanced Entry of Both HCV and SARS-CoV-2 into Hepatocytes and a Coinfection State
  6. 5106
    “…Six months after the primary vaccination with Sputnik V, 95.5% of patients maintained a positive level of IgG antibodies to the receptor-binding domain (RBD) of SARS-CoV-2. The degree of increase in the specific virus-neutralizing antibodies level after revaccination increased with a decrease in their initial level just before the booster dose application. …”
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    Revaccination in Age-Risk Groups with Sputnik V Is Immunologically Effective and Depends on the Initial Neutralizing SARS-CoV-2 IgG Antibodies Level
  7. 5107
    “…ELISA was performed to quantitate serum antibodies against the spike receptor binding domain (RBD). RESULTS: In two persons receiving primary vaccination, tightly serially evaluated frequencies of anti-spike CD8+ T cells using ELISpot assays revealed strikingly short-lived responses, peaking after about 10 days and becoming undetectable by about 20 days after each dose. …”
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    Persistent memory despite rapid contraction of circulating T Cell responses to SARS-CoV-2 mRNA vaccination
  8. 5108
    “…METHODS: In a prospective single-center cohort study we included 54 consecutive adult heart transplant recipients who received 2 doses of mRNA SARS-CoV2 vaccine between January 1 and June 30, 2021. 3 months after the 2(nd) dose, an assessment of humoral (total antibody levels to the receptor-binding domain of SARS-CoV2 spike (S) protein using anti-RBD immunoassay) and cellular (IFN-γ response to S-peptide stimulation of recipient T lymphocyte populations) response to vaccination was assesed. …”
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    (651) Long-Term Safety and Efficacy of Mrna Sars-Cov2 Vaccination in Heart Transplant Recipients
  9. 5109
    “…Our analysis focused on nucleotide mutations that generated amino acid variations in the viral Spike (S) protein, Receptor binding domain (RBD), and the RNA-dependent RNA-polymerase (RdRp) complex. …”
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    Analysis of SARS-CoV-2 variants from patient specimens in Nevada from October 2020 to August 2021
  10. 5110
    por van der Klaauw, Agatha A., Horner, Emily C., Pereyra-Gerber, Pehuén, Agrawal, Utkarsh, Foster, William S., Spencer, Sarah, Vergese, Bensi, Smith, Miriam, Henning, Elana, Ramsay, Isobel D., Smith, Jack A., Guillaume, Stephane M., Sharpe, Hayley J., Hay, Iain M., Thompson, Sam, Innocentin, Silvia, Booth, Lucy H., Robertson, Chris, McCowan, Colin, Kerr, Steven, Mulroney, Thomas E., O’Reilly, Martin J., Gurugama, Thevinya P., Gurugama, Lihinya P., Rust, Maria A., Ferreira, Alex, Ebrahimi, Soraya, Ceron-Gutierrez, Lourdes, Scotucci, Jacopo, Kronsteiner, Barbara, Dunachie, Susanna J., Klenerman, Paul, Park, Adrian J., Rubino, Francesco, Lamikanra, Abigail A., Stark, Hannah, Kingston, Nathalie, Estcourt, Lise, Harvala, Heli, Roberts, David J., Doffinger, Rainer, Linterman, Michelle A., Matheson, Nicholas J., Sheikh, Aziz, Farooqi, I. Sadaf, Thaventhiran, James E. D.
    Publicado 2023
    “…Furthermore, we observed that, for individuals with severe obesity, at any given anti-spike and anti-receptor-binding domain (RBD) antibody level, neutralizing capacity was lower than that of individuals with a normal BMI. …”
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    Accelerated waning of the humoral response to COVID-19 vaccines in obesity
  11. 5111
    “…RESULTS: The geometric mean titre (GMT) of anti-SARS-CoV-2 S-RBD IgG antibody at 8 months after the primary vaccination increased significantly to 5,296.63 (95%CI: 2,930.89–9,571.94) U/mL (p =  < 0.0001) compared to before the primary vaccination. …”
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    Immunogenicity and safety of COVID-19 BNT162b2 booster vaccine in end-stage kidney disease patients receiving haemodialysis in Yogyakarta, Indonesia: a cohort prospective study
  12. 5112
    “…Low rates of seroconversion and RBD-hACE2 blocking activity were observed in aCD20-MS patients, even after multiple exposures (responders after 1st exposure = 17.5%; 2nd exposure = 29.3%). …”
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    Humoral and cellular responses to repeated COVID-19 exposure in multiple sclerosis patients receiving B-cell depleting therapies: a single-center, one-year, prospective study
  13. 5113
    “…Receptor-binding domain (RBD)-specific antibodies were measured at Days 21, 90, 180, 270 and 360. …”
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    Durability and extent of protection of SARS-CoV-2 antibodies among patients with COVID-19 in Metro Manila, Philippines
  14. 5114
    “…BACKGROUND: The entry of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the host cell is mediated through the binding of the SARS-CoV-2 Spike protein via the receptor binding domain (RBD) to human angiotensin-converting enzyme 2 (hACE2). …”
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    A high-throughput screening system for SARS-CoV-2 entry inhibition, syncytia formation and cell toxicity
  15. 5115
    “…Target miRNAs of hub genes were predicted by miRBD and TargetScan. Furthermore, differentially expressed miRNA(DEmiRNAs) were selected as hub genes’ targets, validated by quantitative real-time polymerase chain reaction(qRT-PCR), and a DEmiRNA-DEmRNA regulatory network was constructed via Cytoscape. …”
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    Transcriptome sequencing and microRNA–mRNA regulatory network construction in the lens from a Na(2)SeO(3)-induced Sprague Dawley rat cataract model
  16. 5116
    “…IgG antibodies against the receptor binding domain (RBD) of the SARS-CoV-2 virus were measured in all patients. …”
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    436. SARS-CoV-2 Seropositivity and Association with Dengue Severity in Adults
  17. 5117
    “…HERA-GITRL is composed of a trivalent but single-chain GITRL-receptor-binding-domain (scGITRL-RBD) unit fused to an IgG1 derived silenced Fc-domain serving as dimerization scaffold. …”
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    HERA-GITRL activates T cells and promotes anti-tumor efficacy independent of FcγR-binding functionality
  18. 5118
    por Cashman, Daniel P.
    Publicado 2020
    “…Resolving this paradox requires looking beyond the binary model of a viral receptor-binding domain (RBD) attaching to the ACE-2 receptor. A NCBI pBlast analysis revealed that the SARS-CoV-2 surface spike protein contains key two calcium-dependent fusion domains that are almost identical to those that were recently discovered SARS-CoV-1. …”
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    Why the lower reported prevalence of asthma in patients diagnosed with COVID-19 validates repurposing EDTA solutions to prevent and manage treat COVID-19 disease
  19. 5119
    “…NCI-FNLCR also performed a SARS-CoV-2 spike Receptor Binding Domain (RBD) IgG ELISA. Positive samples were assessed at multiple dilutions. …”
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    LB-15. A Trans-Governmental Collaborative Effort to Independently Evaluate SARS-CoV-2 Serology Assays Using Well-Characterized Sample Panels
  20. 5120
    “…RESULTS: We provided a comprehensive view of mutations from a representative sampling from May to October 2020, highlighting two frequent mutations in spike glycoprotein (D614G and V1176F), an emergent mutation (E484K) in spike Receptor Binding Domain (RBD) characteristic of the B.1.351 and P.1 lineages, and the adjacent replacement of 2 amino acids in Nucleocapsid phosphoprotein (R203K and G204R). …”
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    Genomic epidemiology of SARS-CoV-2 in Esteio, Rio Grande do Sul, Brazil
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