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541por Takheaw, Nuchjira, Liwsrisakun, Chalerm, Chaiwong, Warawut, Laopajon, Witida, Pata, Supansa, Inchai, Juthamas, Duangjit, Pilaiporn, Pothirat, Chaicharn, Bumroongkit, Chaiwat, Deesomchok, Athavudh, Theerakittikul, Theerakorn, Limsukon, Atikun, Tajarernmuang, Pattraporn, Niyatiwatchanchai, Nutchanok, Trongtrakul, Konlawij, Kasinrerk, Watchara“…It is unclear whether anti-RBD IgG levels can predict immunity against VOCs. …”
Publicado 2022
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542“…Therefore, the electrochemical signal of the encapsulated MB in the absence of the SARS-CoV-2-RBD was high. In the presence of SARS-CoV-2-RBD, the aptamers that had a high affinity to the SARS-CoV-2-RBD molecules were removed from the electrode surface to interact with SARS-CoV-2-RBD. …”
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543por Barbier, Mariette, Lee, Katherine S., Vikharankar, Mayur S., Rajpathak, Shriram N., Kadam, Nandkumar, Wong, Ting Y., Russ, Brynnan P., Cyphert, Holly A., Miller, Olivia A., Rader, Nathaniel A., Cooper, Melissa, Kang, Jason, Sen-Kilic, Emel, Wong, Zeriel Y., Winters, Michael T., Bevere, Justin R., Martinez, Ivan, Devarumath, Rachayya, Shaligram, Umesh S., Damron, F. Heath“…We determined that the equine EpF(ab’)(2) bind RBD and neutralize ACE2 receptor binding by virus for all VOC strains tested except Omicron. …”
Publicado 2022
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544por Zhang, Jing, Han, Zi Bo, Liang, Yu, Zhang, Xue Feng, Jin, Yu Qin, Du, Li Fang, Shao, Shuai, Wang, Hui, Hou, Jun Wei, Xu, Ke, Lei, Wenwen, Lei, Ze Hua, Liu, Zhao Ming, Zhang, Jin, Hou, Ya Nan, Liu, Ning, Shen, Fu Jie, Wu, Jin Juan, Zheng, Xiang, Li, Xin Yu, Li, Xin, Huang, Wei Jin, Wu, Gui Zhen, Su, Ji Guo, Li, Qi Ming“…Neutralizing antibody ID50 titers induced by mos-tri-RBD were substantially higher than those elicited by homo-tri-RBD (containing homologous RBDs from prototype strain) or the BIBP inactivated COVID-19 vaccine (BBIBP-CorV). …”
Publicado 2022
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545por Farizano Salazar, Diego H., Achinelli, Fernando, Colonna, Mariana, Pérez, Lucía, Giménez, Analía A., Ojeda, Maria Alejandra, Miranda Puente, Susana N., Sánchez Negrette, Lía, Cañete, Florencia, Martelotte Ibarra, Ornela I., Sanguineti, Santiago, Spatz, Linus, Goldbaum, Fernando A., Massa, Carolina, Rivas, Marta, Pichel, Mariana, Hiriart, Yanina, Zylberman, Vanesa, Gallego, Sandra, Konigheim, Brenda, Fernández, Francisco, Deprati, Matías, Roubicek, Ian, Giunta, Diego H., Nannini, Esteban, Lopardo, Gustavo, Belloso, Waldo H.Enlace del recurso
Publicado 2022
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546por Eka Saputri, Meliana, Aisyah Rahmalia Effendi, Siti, Nadila, Rifa, Azzam Fajar, Syauqi, Damajanti Soejoedono, Retno, Handharyani, Ekowati, Nadia Poetri, Okti“…Our study aimed to evaluate the neutralizing potential of specific IgY targeting S1, receptor-binding-domain (RBD) of spike glycoprotein and nucleocapsid (N) of SARS-CoV-2 to inhibit RBD and angiotensin-converting-enzyme-2 (ACE2) binding interaction. …”
Publicado 2022
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547por Zare, Hamed, Rezapour, Hadis, Fereidouni, Alireza, Nikpour, Saboura, Mahmoudzadeh, Sara, Royce, Simon G, Fereidouni, MohammadEnlace del recurso
Publicado 2022
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548por Abu-Humaidan, Anas H. A., Ahmad, Fatima M., Awajan, Dima, Jarrar, Raba'a F., Alaridah, Nader“…Participants who received either one or two doses of BNT162b2 formed higher levels of anti-RBD IgG and IgA than participants who received BBIBP-CorV. …”
Publicado 2022
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549por Gupta, Deepali, Kumar, Mukesh, Sharma, Priyanka, Mohan, Trishala, Prakash, Amresh, Kumari, Renu, Kaur, Punit“…In the current scenario, several lineages containing “co-mutations” in the receptor-binding domain (RBD) region of the spike (S) protein are imposing new challenges. …”
Publicado 2022
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550por Aguilar, Ruth, Li, Xue, Crowell, Claudia S., Burrell, Teresa, Vidal, Marta, Rubio, Rocio, Jiménez, Alfons, Hernández-Luis, Pablo, Hofmann, Dieter, Mijočević, Hrvoje, Jeske, Samuel, Christa, Catharina, D'Ippolito, Elvira, Lingor, Paul, Knolle, Percy A., Roggendorf, Hedwig, Priller, Alina, Yazici, Sarah, Carolis, Carlo, Mayor, Alfredo, Schreiner, Patrik, Poppert, Holger, Beyer, Henriette, Schambeck, Sophia E., Izquierdo, Luis, Tortajada, Marta, Angulo, Ana, Soutschek, Erwin, Engel, Pablo, Garcia-Basteiro, Alberto, Busch, Dirk H., Moncunill, Gemma, Protzer, Ulrike, Dobaño, Carlota, Gerhard, Markus“…Both cohorts showed a high positive correlation between IgG levels to S antigen, especially to RBD, and the levels of plasma surrogate-neutralizing activity, suggesting RBD IgG as a good correlate of plasma neutralizing activity. …”
Publicado 2023
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551por Feitsma, Eline A., Janssen, Yester F., Boersma, Hendrikus H., van Sleen, Yannick, van Baarle, Debbie, Alleva, David G., Lancaster, Thomas M., Sathiyaseelan, Thillainaygam, Murikipudi, Sylaja, Delpero, Andrea R., Scully, Melanie M., Ragupathy, Ramya, Kotha, Sravya, Haworth, Jeffrey R., Shah, Nishit J., Rao, Vidhya, Nagre, Shashikant, Ronca, Shannon E., Green, Freedom M., Aminetzah, Ari, Sollie, Frans, Kruijff, Schelto, Brom, Maarten, van Dam, Gooitzen M., Zion, Todd C.“…BACKGROUND: Previous interim data from a phase I study of AKS-452, a subunit vaccine comprising an Fc fusion of the respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein receptor binding domain (SP/RBD) emulsified in the water-in-oil adjuvant, Montanide™ ISA 720, suggested a good safety and immunogenicity profile in healthy adults. …”
Publicado 2023
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552“…This study evaluated the diagnostic performance of the RapiSure (EDGC) COVID-19 S1 RBD IgG/Neutralizing Ab Test. Using the 90% plaque reduction neutralization test (PRNT(90)) as a reference, 200 serum samples collected from 78 COVID-19-positive and 122 COVID-19-negative patients were divided into 76 PRNT(90)-positive and 124 PRNT(90)-negative groups. …”
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553por Chatterjee, Srijan, Bhattacharya, Manojit, Dhama, Kuldeep, Lee, Sang-Soo, Chakraborty, ChiranjibEnlace del recurso
Publicado 2023
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554por Gonzalez-Hernandez, Mariana, Kaiser, Franziska Karola, Steffen, Imke, Ciurkiewicz, Malgorzata, van Amerongen, Geert, Tchelet, Ronen, Emalfarb, Mark, Saloheimo, Markku, Wiebe, Marilyn G., Vitikainen, Marika, Albulescu, Irina C., Bosch, Berend-Jan, Baumgärtner, Wolfgang, Haagmans, Bart L., Osterhaus, Albert D. M. E.“…The receptor-binding domain (RBD) of the SARS-CoV-2 spike (S) protein is the main target for virus neutralizing (VN) antibodies. …”
Publicado 2023
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555por Passariello, Margherita, Esposito, Speranza, Manna, Lorenzo, Rapuano Lembo, Rosa, Zollo, Immacolata, Sasso, Emanuele, Amato, Felice, De Lorenzo, Claudia“…Furthermore, we report that the ability of D3 to bind the recombinant Omicron RBD domain in vitro results in a good ability to also neutralize Omicron-pseudotyped virus infection in ACE2-expressing cell cultures. …”
Publicado 2023
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556por Lee, Katherine S, Rader, Nathaniel A, Miller, Olivia A, Cooper, Melissa, Wong, Ting Y, Shahrier Amin, Md., Barbier, Mariette, Bevere, Justin R, Ernst, Robert K, Heath Damron, F.“…K18-hACE2 mice were primed and boosted at four-week intervals with either VLP-RBD-BECC or mRNA-1273. Both VLP-RBD-BECC and mRNA-1273 vaccination resulted in production of RBD-specific IgA antibodies in serum. …”
Publicado 2023
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557por Bindoli, Sara, Baggio, Chiara, Galozzi, Paola, Vesentini, Filippo, Doria, Andrea, Cosma, Chiara, Padoan, Andrea, Sfriso, PaoloEnlace del recurso
Publicado 2023
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558por Chen, Wen-Hsiang, Tao, Xinrong, Agrawal, Anurodh, Algaissi, Abdullah, Peng, Bi-Hung, Pollet, Jeroen, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Du, Lanying, Jiang, Shibo, Tseng, Chien-Te K.“…An RBD219-N1 formulation Alhydrogel® was also superior to the S protein, unadjuvanted RBD, and AddaVax (MF59-like adjuvant)-formulated RBD in inducing specific antibodies and preventing cellular infiltrates in the lungs upon SARS-CoV challenge. …”
Publicado 2020
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559“…A SARS-CoV receptor-binding domain (RBD) recombinant protein was developed and manufactured under current good manufacturing practices in 2016. …”
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560por Chen, Wen-Hsiang, Tao, Xinrong, Agrawal, Anurodh Shankar, Algaissi, Abdullah, Peng, Bi-Hung, Pollet, Jeroen, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Du, Lanying, Jiang, Shibo, Tseng, Chien-Te K.“…An RBD219-N1 formulation with Alhydrogel® was also superior to the S protein, unadjuvanted RBD, and AddaVax (MF59-like adjuvant)-formulated RBD in inducing specific antibodies and preventing cellular infiltrates in the lungs upon SARS-CoV challenge. …”
Publicado 2020
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