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641por Bauer, Georg, Struck, Friedhelm, Staschik, Eva, Maile, Julia, Wochinz‐Richter, Karin, Motz, Manfred, Soutschek, Erwin“…In contrast, the avidity of IgG cross‐reacting with RBD of the omicron variant was always much lower than for IgG RBD WT, except after the third vaccination step. …”
Publicado 2022
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642por Gil-Manso, Sergio, Alonso, Roberto, Catalán, Pilar, Sánchez-Arcilla, Ignacio, Marzola, Marco, Correa-Rocha, Rafael, Pion, Marjorie, Muñoz, Patricia“…Therefore, the objective of this study was to recruit a large cohort of healthcare workers from the Gregorio Marañón Hospital vaccinated with the mRNA-1273 or BNT126b2 vaccines and to follow-up on IgG anti-RBD levels at 8 months post-vaccination. METHODS: We recruited 4,970 volunteers and measured IgG anti-RBD antibodies on days 30 and 240 post-vaccination. …”
Publicado 2022
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643por Rachman, Andhika, Iriani, Anggraini, Priantono, Dimas, Rumondor, Bayu Bijaksana, Betsy, Rachelle, Juanputra, Samuel“…The seropositivity of S-RBD IgG and NAb reached 93.3 and 94.1%, respectively. …”
Publicado 2022
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644por Zhang, Ruiqi, Chan, Kwok-Hung, Wang, Pui, Zhou, Runhong, Yau, Henry Kwong-Chi, Wong, Creany Ka-Wai, Au, Meena Wai-Lam, Tam, Anthony Raymond, Ng, Chi-Tao, Lou, Matthew Kwok-Chung, Liu, Na, Huang, Haode, Deng, Shaofeng, Tam, Rachel Chun-Yee, Liu, Ying, Long, Teng, Tsoi, Hoi-Wah, Ng, Miko K. W., Cai, Jian-Piao, To, Kelvin Kai-Wang, Yuen, Man-Fung, Chen, Zhiwei, Chen, Honglin, Yuen, Kwok-Yung, Hung, Ivan Fan-Ngai“…An intranasal COVID-19 vaccine, DelNS1-based RBD vaccines composed of H1N1 subtype (DelNS1-nCoV-RBD LAIV) was developed to evaluate the safety and immunogenicity in healthy adults. …”
Publicado 2023
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645por Fan, Feng, Zhang, Xin, Zhang, Zhiyu, Ding, Yuan, Wang, Limei, Xu, Xin, Pan, Yaying, Gong, Fang-Yuan, Jiang, Lin, Kang, Lingyu, Ha, Zhuo, Lu, Huijun, Hou, Jiawang, Kou, Zhihua, Zhao, Gan, Wang, Bin, Gao, Xiao-Ming“…In this study, we constructed pVAX1-based plasmids encoding receptor-binding domain (RBD) chimera of SARS-CoV-1 and SARS-CoV-2 variants, including pAD1002 (encoding RBD(SARS/BA1)), pAD1003 (encoding RBD(SARS/Beta)) and pAD131 (encoding RBD(BA1/Beta)). …”
Publicado 2023
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646por Hernández-Bernal, Francisco, Ricardo-Cobas, Maria C., Martín-Bauta, Yenima, Rodríguez-Martínez, Ernesto, Urrutia-Pérez, Klaudia, Urrutia-Pérez, Karen, Quintana-Guerra, Joel, Navarro-Rodríguez, Zadis, Piñera-Martínez, Marjoris, Rodríguez-Reinoso, José L., Chávez-Chong, Cristina O., Baladrón-Castrillo, Idania, Melo-Suárez, Grettel, Batista-Izquierdo, Alejandro, Pupo-Micó, Alexis, Mora-Betancourt, Ricardo, Bizet-Almeida, Jacqueline, Martínez-Rodríguez, Maria C., Lobaina-Lambert, Leonardo, Velázquez-Pérez, Vivian M., Soler-Díaz, Jalimy, Laurencio-Vallina, Sandra, Meriño-Hechavarría, Tamara, Carmenaty-Campos, Norberto, Rodríguez-Montero, Enri, Limonta-Fernández, Miladys, Alonso-Valdés, Marel, Hernández-Rodríguez, Reinier, Pimentel-Vázquez, Eulogio, Catasús-Álvarez, Karem M., Cabrera-Núñez, Maria V., Ayala-Ávila, Marta, Muzio-González, Verena L.“…We evaluated the efficacy and safety of a new SARS-CoV-2 virus receptor-binding domain (RBD) vaccine. METHODS: A phase 3, multicentre, randomised, double-blind, placebo-controlled trial was carried out at 18 clinical sites in three provinces of the south-eastern region of Cuba. …”
Publicado 2023
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647por Wan Shuaib, Wan Muhammad Azfar, Badaruddin, Izzatul Aliaa, Mansor, Munirah, Salleh, Sharifah Azura, Hassan, Mohd Rohaizat, Lindong, Steward, Samad, Shahril Nizam, Othman, Hanita“…Hence, we would like to investigate factors affecting the production of S-RBD IgG and NTAb among different categories of HCWs, particularly after receiving the third dose of the BNT162b2 mRNA COVID-19 Vaccine. …”
Publicado 2023
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648por Boroduske, Anete, Jekabsons, Kaspars, Riekstina, Una, Muceniece, Ruta, Rostoks, Nils, Nakurte, Ilva“…Concentration-dependent inhibition of ACE2-SARS-CoV2 S-protein RBD binding was demonstrated in vitro for elderberry fruits and flowers extracts (IC50 of 1.66 mg DW ml(−1) and 0.532 mg DW ml(−1), respectively). …”
Publicado 2021
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649por Ye, Fei, Lin, Xi, Chen, Zimin, Yang, Fanli, Lin, Sheng, Yang, Jing, Chen, Hua, Sun, Honglu, Wang, Lingling, Wen, Ao, Zhang, Xindan, Dai, Yushan, Cao, Yu, Yang, Jingyun, Shen, Guobo, Yang, Li, Li, Jiong, Wang, Zhenling, Wang, Wei, Wei, Xiawei, Lu, Guangwen“…SARS-CoV-2 recognizes, via its spike receptor-binding domain (S-RBD), human angiotensin-converting enzyme 2 (ACE2) to initiate infection. …”
Publicado 2021
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651por Durmaz, Vedat, Köchl, Katharina, Krassnigg, Andreas, Parigger, Lena, Hetmann, Michael, Singh, Amit, Nutz, Daniel, Korsunsky, Alexander, Kahler, Ursula, König, Centina, Chang, Lee, Krebs, Marius, Bassetto, Riccardo, Pavkov-Keller, Tea, Resch, Verena, Gruber, Karl, Steinkellner, Georg, Gruber, Christian C.“…For the latest variant of concern (VOC), B.1.1.529 Omicron, our Halo difference point cloud studies reveal the largest impact on the RBD binding interface compared to all other VOC. …”
Publicado 2022
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652por Balasubramaniyam, Arasu, Ryan, Emma, Brown, Dallas, Hamza, Therwa, Harrison, William, Gan, Michael, Sankhala, Rajeshwer S., Chen, Wei-Hung, Martinez, Elizabeth J., Jensen, Jaime L., Dussupt, Vincent, Mendez-Rivera, Letzibeth, Mayer, Sandra, King, Jocelyn, Michael, Nelson L., Regules, Jason, Krebs, Shelly, Rao, Mangala, Matyas, Gary R., Joyce, M. Gordon, Batchelor, Adrian H., Gromowski, Gregory D., Dutta, Sheetij“…The RBD of the original Wuhan-Hu1 variant and of the Alpha and Beta variants of concern (VoC) were expressed in E. coli, and their biochemical and immunological profiles were compared to RBD produced in mammalian cells. …”
Publicado 2022
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653por Duan, Minrun, Duan, Huixin, An, Yaling, Zheng, Tianyi, Wan, Shengfeng, Wang, Hui, Zhao, Xin, Dai, Lianpan, Xu, Kun, Gao, George F.“…To adapt SARS-CoV-2 variants, we further developed chimeric Delta-Omicron BA.1 RBD-dimer immunogen which induced broad immune responses against SARS-CoV-2 variants. …”
Publicado 2023
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654por Bai, Yu, An, Chaoqiang, Zhang, Xuanxuan, Li, Kelei, Cheng, Feiran, Cui, Bopei, Song, Ziyang, Liu, Dong, Zhang, Jialu, He, Qian, Liu, Jianyang, Mao, Qunying, Liang, Zhenglun“…In addition, D-O RBD + AT149 and D-O RBD + Al + AT149 groups presented higher levels of the T-cell-secreted IFN-γ immune response. …”
Publicado 2023
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655por Yang, Shilong, Li, Yan, Dai, Lianpan, Wang, Jianfeng, He, Peng, Li, Changgui, Fang, Xin, Wang, Chenfei, Zhao, Xiang, Huang, Enqi, Wu, Changwei, Zhong, Zaixin, Wang, Fengze, Duan, Xiaomin, Tian, Siyu, Wu, Lili, Liu, Yan, Luo, Yi, Chen, Zhihai, Li, Fangjun, Li, Junhua, Yu, Xian, Ren, Hong, Liu, Lihong, Meng, Shufang, Yan, Jinghua, Hu, Zhongyu, Gao, Lidong, Gao, George F“…We developed a protein subunit vaccine against COVID-19 using a dimeric form of the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein as the antigen. …”
Publicado 2021
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656por Lopardo, Gustavo, Belloso, Waldo H., Nannini, Esteban, Colonna, Mariana, Sanguineti, Santiago, Zylberman, Vanesa, Muñoz, Luciana, Dobarro, Martín, Lebersztein, Gabriel, Farina, Javier, Vidiella, Gabriela, Bertetti, Anselmo, Crudo, Favio, Alzogaray, Maria Fernanda, Barcelona, Laura, Teijeiro, Ricardo, Lambert, Sandra, Scublinsky, Darío, Iacono, Marisa, Stanek, Vanina, Solari, Rubén, Cruz, Pablo, Casas, Marcelo Martín, Abusamra, Lorena, Luciardi, Héctor Lucas, Cremona, Alberto, Caruso, Diego, de Miguel, Bernardo, Lloret, Santiago Perez, Millán, Susana, Kilstein, Yael, Pereiro, Ana, Sued, Omar, Cahn, Pedro, Spatz, Linus, Goldbaum, FernandoEnlace del recurso
Publicado 2021
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657por Trougakos, Ioannis P., Terpos, Evangelos, Zirou, Christina, Sklirou, Aimilia D., Apostolakou, Filia, Gumeni, Sentiljana, Charitaki, Ioanna, Papanagnou, Eleni-Dimitra, Bagratuni, Tina, Liacos, Christine-Ivy, Scorilas, Andreas, Korompoki, Eleni, Papassotiriou, Ioannis, Kastritis, Efstathios, Dimopoulos, Meletios A.“…In support, high anti-spike-RBD IgGs/NAbs titers along with spike (vaccine encoded antigen) specific T cell clones were found in the serum and peripheral blood mononuclear cells, respectively, of vaccinated individuals 5 months post-vaccination. …”
Publicado 2021
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658por Salvagno, Gian Luca, Henry, Brandon M., di Piazza, Giovanni, Pighi, Laura, de Nitto, Simone, Bragantini, Damiano, Gianfilippi, Gian Luca, Lippi, Giuseppe“…We then measured anti-spike trimeric IgG (Liaison XL, DiaSorin), anti-spike receptor binding domain (RBD) IgG (Access 2, Beckman Coulter) and anti-spike S1 subunit IgA (ELISA, Euroimmun). …”
Publicado 2021
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659por Bachelet, Thomas, Bourdenx, Jean-Philippe, Martinez, Charlie, Mucha, Simon, Martin-Dupont, Philippe, Perier, Valerie, Pommereau, Antoine“…We report our experience with a BNT162b2-mRNA vaccine in a retrospective analysis of 241 dialysis patients including 193 who underwent anti-Spike-Protein-Receptor-Binding-Domain (RBD) IgG analysis. We show that a pro-active vaccine campaign is effective in convincing most patients to be vaccinated (95%) and frequently elicits a specific antibody response (94.3% after two doses and 98.4% after three doses). …”
Publicado 2021
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660por Cristiano, Antonio, Pieri, Massimo, Sarubbi, Serena, Pelagalli, Martina, Calugi, Graziella, Tomassetti, Flaminia, Bernardini, Sergio, Nuccetelli, Marzia“…The Spike-Receptor Binding Domain (S-RBD) is considered the most antigenic protein in SARS-CoV-2 and probably the key player in SARS-CoV-2 immune response. …”
Publicado 2022
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