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761por Tantiwiwat, Termsak, Thaiprayoon, Apisitt, Siriatcharanon, Ake-kavitch, Tachaapaikoon, Chakrit, Plongthongkum, Nongluk, Waraho-Zhmayev, Dujduan“…Next, we conducted a head-to-head comparison of the binding activity of our E. coli-produced RBD (E-RBD) with commercial HEK293-produced RBD (H-RBD). …”
Publicado 2022
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762por Perez-Lloret, Santiago, Chevalier, Guenson, Bordet, Sofia, Barbar, Hanny, Capani, Francisco, Udovin, Lucas, Otero-Losada, Matilde“…Patients with Parkinson’s Disease (PD) experience REM sleep behavior disorder (RBD) more frequently than healthy controls. RBD is associated with torpid disease evolution. …”
Publicado 2023
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763por Rolinski, Michal, Szewczyk-Krolikowski, Konrad, Tomlinson, Paul R, Nithi, Kannan, Talbot, Kevin, Ben-Shlomo, Yoav, Hu, Michele TM“…BACKGROUND: Concomitant REM sleep behaviour disorder (RBD) is commonly observed in patients with Parkinson's disease (PD). …”
Publicado 2014
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764por Ozharovskaia, T. A., Zubkova, O. V., Dolzhikova, I. V., Gromova, A. S., Grousova, D. M., Tukhvatulin, A. I., Popova, O., Shcheblyakov, D. V., Scherbinin, D. N., Dzharullaeva, A. S., Erokhova, A. S., Shmarov, M. M., Loginova, S. Y., Borisevich, S. V., Naroditsky, B. S., Logunov, D. Y., Gintsburg, A. L.“…In the present study, the immunogenicities of five different forms of the MERS-CoV S glycoprotein were compared: the full-length S glycoprotein, the full-length S glycoprotein with the transmembrane domain of the G glycoprotein of VSV (S-G), the receptor-binding domain (RBD) of the S glycoprotein, the membrane-fused RBD (the RBD fused with the transmembrane domain of the VSV G glycoprotein (RBD-G)), and the RBD fused with Fc of human IgG1 (RBD-Fc). …”
Publicado 2019
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765por Yuan, Yuan, Zhang, Yimeng, Cheng, Yueyang, Hou, Yue, Huang, Zhaoyang, Ma, Jinghong, Li, Ning, Zhan, Shuqin“…Tumor necrosis factor α (TNF-α) plays a part in the pathology of PD and disease conversion in isolated RBD (iRBD). TNF can also directly impair the hypocretin system in mice in vivo. …”
Publicado 2022
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766por Sabzian-Molaei, Fatemeh, Nasiri Khalili, Mohammad Ali, Sabzian-Molaei, Mohammad, Shahsavarani, Hosein, Fattah Pour, Alireza, Molaei Rad, Ahmad, Hadi, Amin“…Here, we studied the interaction between UDA and RBD of Spike protein of SARS-CoV-2. So, protein-protein docking of RBD-UDA was performed using Cluspro 2.0. …”
Publicado 2022
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767“…Idiopathic rapid eye movement sleep behavior disorder (iRBD) is an important non-motor complication of Parkinson's disease. …”
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768por Chwiszczuk, Luiza, Breitve, Monica Haraldseid, Brønnick, Kolbjørn, Gjerstad, Michaela D., Hynninen, Minna, Aarsland, Dag, Rongve, Arvid“…A diagnosis of probable RBD (pRBD) was made based on the Mayo Sleep Questionnaire. …”
Publicado 2017
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769por Bušková, Jitka, Peřinová, Pavla, Miletínová, Eva, Dušek, Petr, Růžička, Evžen, Šonka, Karel, Kemlink, David“…RESULTS: The mean RBD-SQ score in the iRBD patients was 9.4 ± 2.8 points, and in the non-RBD group it was 4.5 ± 3.0 (P < 0.0001). …”
Publicado 2019
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770An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccinespor Quinlan, Brian D., He, Wenhui, Mou, Huihui, Zhang, Lizhou, Guo, Yan, Chang, Jing, Peng, Shoujiao, Ojha, Amrita, Tavora, Rubens, Parcells, Mark S., Luo, Guangxiang, Li, Wenhui, Zhong, Guocai, Choe, Hyeryun, Farzan, Michael“…Further, gRBD is more immunogenic than the wild-type RBD when administered as a subunit protein vaccine. …”
Publicado 2020
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771An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccinespor Guo, Yan, He, Wenhui, Mou, Huihui, Zhang, Lizhou, Chang, Jing, Peng, Shoujiao, Ojha, Amrita, Tavora, Rubens, Parcells, Mark S., Luo, Guangxiang, Li, Wenhui, Zhong, Guocai, Choe, Hyeryun, Farzan, Michael, Quinlan, Brian D.“…Further, gRBD is more immunogenic than the wild-type RBD when administered as a subunit protein vaccine. …”
Publicado 2021
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772por Guo, Qiao, Yang, Lei, Peng, Ran, Gao, Tao, Chu, Xinglin, Jiang, Depeng, Ke, Dazhi, Ren, Hong“…The B cells, mainly including RBD-specific B cells, RBD-specific memory B cell (MBC), RBD(+) resting MBC cells, RBD(+) activated MBC cells, RBD(+) atypical MBC cells (atyMBCs), and RBD(+) intermediate MBC cells, were also analyzed. …”
Publicado 2022
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773“…REM Sleep Behavior Disorder (RBD) is a chronic sleep condition characterized by dream enactment and loss of REM atonia. …”
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774por Ma, Huan, Zeng, Weihong, Meng, Xiangzhi, Huang, Xiaoxue, Yang, Yunru, Zhao, Dan, Zhou, Peigen, Wang, Xiaofang, Zhao, Changcheng, Sun, Yong, Wang, Peihui, Ou, Huichao, Hu, Xiaowen, Xiang, Yan, Jin, Tengchuan“…As such, RBD has become the major target for vaccine development, whereas RBD-specific antibodies are pursued as therapeutics. …”
Publicado 2021
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775“…In this article, we investigate the binding processes of a fragment of the coronavirus spike protein receptor binding domain (RBD), the hexapeptide YKYRYL on the angiotensin-converting enzyme 2 (ACE2) receptor, and its inhibitory effect on the binding and activation of the coronavirus-2 spike protein CoV-2 RBD at ACE2. …”
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776por Jiménez-Jiménez, Félix Javier, Alonso-Navarro, Hortensia, García-Martín, Elena, Agúndez, José A. G.“…The symptomatic treatment of REM sleep behaviour disorder (RBD) is very important to prevent sleep-related falls and/or injuries. …”
Publicado 2021
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777por Ngo, Son Tung, Nguyen, Trung Hai, Pham, Duc-Hung, Tung, Nguyen Thanh, Nam, Pham Cam“…Moreover, the fragment of NAb + RBD can be used as an affordable model to investigate changes in the binding process between the mutated RBD and antibodies.…”
Publicado 2021
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778por Yamamoto, Janet K., Edison, Lekshmi K., Rowe-Haas, Dawne K., Takano, Tomomi, Gilor, Chen, Crews, Chiquitha D., Tuanyok, Apichai, Arukha, Ananta P., Shiomitsu, Sayaka, Walden, Heather D. S., Hohdatsu, Tsutomu, Tompkins, Stephen M., Morris Jr., John G., Sahay, Bikash, Kariyawasam, Subhashinie“…The sera from toms and queens cross-reacted with SCoV2 RBD and reacted with FCoV1 RBD and FCoV2 spike-2, nucleocapsid, and membrane proteins, but not with FCoV2 RBD. …”
Publicado 2023
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779“…The receptor-binding domain (RBD) is located on the spike S-protein’s S1 subunit of the spike glycoprotein. …”
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780por Tang, Wai Kwong, Hermann, Dirk M, Chen, Yang Kun, Liang, Hua Jun, Liu, Xiang Xin, Chu, Winnie Chui Wing, Ahuja, Anil T, Abrigo, Jill, Mok, Vincent, Ungvari, Gabor S, Wong, Ka Sing“…BACKGROUND: Rapid eye movement (REM) sleep behavior disorder (RBD) is a sleep disturbance in which patients enact their dreams while in REM sleep. …”
Publicado 2014
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