Mostrando 801 - 820 Resultados de 5,191 Para Buscar '"RBD"', tiempo de consulta: 0.20s Limitar resultados
  1. 801
    “…Analysis of sera from RBD-positive and RBD-negative individuals revealed further that non-infected RBD-negative blood group O individuals have antibodies that strongly bind to RBD modified with blood group A antigen structures. …”
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    In Planta Production of the Receptor-Binding Domain From SARS-CoV-2 With Human Blood Group A Glycan Structures
  2. 802
    “…By using our pipeline, we built 3D comparative models of the SARS-CoV-2 spike RBD/ACE2 protein complexes for the VoC B.1.1.7-United Kingdom (carrying the mutations of concern/interest N501Y, S494P, E484K at the RBD), P.1-Japan/Brazil (RBD mutations: K417T, E484K, N501Y), B.1.351-South Africa (RBD mutations: K417N, E484K, N501Y), B.1.427/B.1.429-California (RBD mutations: L452R), the B.1.141 (RBD mutations: N439K), and the recent B.1.617.1-India (RBD mutations: L452R; E484Q) and the B.1.620 (RBD mutations: S477N; E484K). …”
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    Modeling SARS-CoV-2 spike/ACE2 protein–protein interactions for predicting the binding affinity of new spike variants for ACE2, and novel ACE2 structurally related human protein targets, for COVID-19 handling in the 3PM context
  3. 803
    “…METHODS: We prospectively measured the total (TAbs-RBD) and the neutralizing antibodies (NAbs-RBD) against the receptor binding domain (RBD) of SARS-CoV-2 spike protein in a cohort of 268 Healthcare workers before immunization, 20 days after the 1(st) dose and 30 days after the 2(nd) dose of the BNT162b2 vaccine. …”
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    Association of total and neutralizing SARS-CoV-2 spike -receptor binding domain antibodies with epidemiological and clinical characteristics after immunization with the 1(st) and 2(nd) doses of the BNT162b2 vaccine
  4. 804
    “…Beyond the brainstem, it is unclear if RBD patients comorbid with PD have more affected striatal dopamine denervation compared to PD patients unaffected by RBD (PD-RBD−). …”
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    VMAT2 availability in Parkinson’s disease with probable REM sleep behaviour disorder
  5. 805
    por Coussens, S, Cava, M
    Publicado 2023
    “…Rapid Eye Movement (REM) Behaviour Disorder (RBD) is a sleep disorder characterized by the absence of muscle paralysis during REM sleep, leading to the enactment of dream content. …”
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    P046 Knowledge of REM Behaviour Disorder Among Sleep Technicians in Australia
  6. 806
    “…Here we used CHO-K1 cells to establish a cell line for stable expression of a 193-mer (residues 318–510) RBD (RBD193-CHO) and determined its antigenicity and immunogenicity. …”
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    Antigenicity and immunogenicity of SARS-CoV S protein receptor-binding domain stably expressed in CHO cells
  7. 807
    “…DISCUSSION: PD patients with RBD symptoms had worse motor findings than those unlikely to have RBD. …”
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    REM Sleep Behavior and Motor Findings in Parkinson's Disease: A Cross-sectional Analysis
  8. 808
    “…We hypothesized that SNCA variants conferring risk of Parkinson’s disease would also predispose to an RBD phenotype. METHODS: We assessed possible RBD (pRBD) status using the RBD screening questionnaire and investigated known susceptibility variants for Parkinson’s disease located in the α-synuclein (SNCA) and tau (MAPT) gene loci in 325 Parkinson’s disease patients. …”
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    Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association study
  9. 809
    “…We adopted the latest Seed-based d Mapping with Permutation of Subject Images technique to quantitatively estimate the difference of regional GM volume between PD patients with and without RBD. Results: We included five studies comprising 105 PD patients with RBD and 140 PD patients without RBD. …”
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    Gray Matter Alterations in Parkinson's Disease With Rapid Eye Movement Sleep Behavior Disorder: A Meta-Analysis of Voxel-Based Morphometry Studies
  10. 810
    “…OBJECTIVE: Rapid-Eye-Movement (REM) sleep behaviour disorder (RBD) is an early predictor of Parkinson’s disease, dementia with Lewy bodies, and multiple system atrophy. …”
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    Proof of concept: Screening for REM sleep behaviour disorder with a minimal set of sensors
  11. 811
    “…This study aimed to identify an association between PTSD and potential pRBD in Mexico. An anonymous online survey of 4502 urban college-educated adults, 29.3 ± 10.3 years; MMC, n = 1865; non-MMC, n = 2637, measured PTSD symptoms using the Impact of Event Scale–Revised (IES-R) and pRBD symptoms using the RBD Single-Question. …”
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    Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders
  12. 812
    “…Background: Subjective gastrointestinal complaints have been repeatedly reported in patients with REM sleep behavior disorder (RBD), but objective evidence is scarce. We aimed to objectively investigate the gastrointestinal dysfunction in individuals with probable RBD (pRBD) using an electrogastrogram. …”
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    Gastric Electrical Dysarrhythmia in Probable Rapid Eye Movement Sleep Behavior Disorder
  13. 813
    “…The dissociation constant of (124)I-RBD binding to hACE2 was 75.7 nM. The uptake of (124)I-RBD by HeLa(ACE+) cells at 2 h was 2.96% ± 0.35%, which could be substantially blocked by an excessive amount of RBD, and drop to 1.71% ± 0.23%. …”
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    SARS-CoV-2 receptor binding domain radio-probe: a non-invasive approach for angiotensin-converting enzyme 2 mapping in mice
  14. 814
    “…Here, we generated fusion proteins composed of the extracellular portions of ACE2 and RBD fused to the Fc portion of human IgG1 (ACE2-Ig and RBD-Ig, respectively). …”
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    SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection
  15. 815
    “…Several lines of evidence suggest that binding SARS-CoV-2 antibodies such as anti-SARS-CoV-2 RBD IgG (anti-RBD) and neutralising antibodies (NA) are correlates of protection against SARS-CoV-2, and the correlation of anti-RBD and NA is very high. …”
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    Modelling SARS-CoV-2 Binding Antibody Waning 8 Months after BNT162b2 Vaccination
  16. 816
    “…The authors aimed to optimize RBD produced in HEK293‐6E cells towards a stable homogeneous preparation and addressed its O‐glycosylation as well as the unpaired cysteine residue 538 in the widely used RBD (319‐541) sequence. …”
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    Designed SARS‐CoV‐2 receptor binding domain variants form stable monomers
  17. 817
    “…Among these nanobodies H11-H4 and H11-D4 bind RBD without overlapping ACE2. They were unable to dislocate ACE2 from RBD(Delta) when bound side by side with ACE2 on RBD. …”
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    SARS-CoV-2 Delta Variant Decreases Nanobody Binding and ACE2 Blocking Effectivity
  18. 818
    “…We identified two mutated aptamers, namely, RBD-1CM1 and RBD-1CM2, which presented better docking results against the S protein compared with the RBD-1C aptamer. …”
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    In-Silico Selection of Aptamer Targeting SARS-CoV-2 Spike Protein
  19. 819
    “…Intranasal immunization using the receptor-binding domain (RBD) of MERS-CoV spike protein (S-RBD) recombined with LL-37 (S-RBD-LL-37) induced an efficient mucosal IgA and systemic IgG response with virus-neutralizing activity, compared with S-RBD. …”
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    Application of Antimicrobial Peptide LL-37 as an Adjuvant for Middle East Respiratory Syndrome-Coronavirus Antigen Induces an Efficient Protective Immune Response Against Viral Infection After Intranasal Immunization
  20. 820
    “…Among the novel mutations distinguishing SARS-CoV-2 from similar coronaviruses is a K403R substitution in the receptor-binding domain (RBD) of the viral spike (S) protein within its S1 region. …”
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    Receptor-binding domain of SARS-CoV-2 is a functional αv-integrin agonist
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