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821“…Rapid eye movement sleep behavior disorder (RBD) is a sleep behavior disorder characterized by abnormal behaviors and loss of muscle atonia during rapid eye movement (REM) sleep. …”
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822por Yan, Junqiang, Liu, Anran, Huang, Jiarui, Wu, Jiannan, Shen, Ruile, Ma, Hongxia, Yang, Jianxue“…We evaluated the safety and efficacy of pharmacological intervention to improve RBD in patients with Parkinson's disease (PD-RBD). …”
Publicado 2021
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823por Arias-Arias, Jorge L., Molina-Castro, Silvia E., Monturiol-Gross, Laura, Lomonte, Bruno, Corrales-Aguilar, Eugenia“…SARS-CoV-2 receptor binding domain (RBD) recognizes the angiotensin converting enzyme 2 (ACE2) receptor in host cells that enables infection. …”
Publicado 2022
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824por Moro-Pérez, Leina, Boggiano-Ayo, Tammy, Lozada-Chang, Sum Lai, Fernández-Saiz, Olga Lidia, de la Luz, Kathya Rashida, Gómez-Pérez, Jose Alberto“…In this sense, the antigens of the vaccine platform Soberana, the receptor binding domain from SARS-CoV-2 Spike protein, both the monomeric (mRBD) and dimeric (dRBD) forms, have been developed. …”
Publicado 2023
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825por Wiwe, Elias F, Carlsson, Elin R, Rasmussen, Christina L, Rasmussen, Pernille, Ougaard, Robert, Hansen, Steen I, Schiøler, Thomas, Kristiansen, Søren, Hansen, Young B, Hillig, Thore“…We investigated diagnostic sensitivity and specificity against consensus and PCR and interassay agreement over time for 5 SARS-CoV-2 immunoassays [Roche-nucleocapsid (NC)-total, Roche-receptor binding domain (RBD)-total, Siemens-RBD-IgG, Siemens-RBD-total, Thermo Fisher Scientific (TFS)-RBD-IgG] commercially available on automated platforms and 2 ELISA assays (TFS-RBD-total, Wantai-RBD-total). …”
Publicado 2022
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826por Nielsen, Bibi Uhre, Drabe, Camilla Heldbjerg, Barnkob, Mike Bogetofte, Johansen, Isik Somuncu, Hansen, Anne Kirstine Kronborg, Nilsson, Anna Christine, Rasmussen, Line Dahlerup“…Moreover, we measured anti-S-RBD after treatment with mAB. Finally, anti-S-RBD was assessed in common IgRT products. …”
Publicado 2022
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827por Sabzian-Molaei, Fatemeh, Hosseini, Seyedrafi, Alipour, Atefeh, Ghaderi, Hajarossadat, Fotouhi-Chahouki, Fatemeh, Hadi, Amin, Shahsavarani, Hosein“…Also, the ELISA test showed that UDA significantly binds to RBD(Omic), and by increasing the concentration of UDA protein, the attachment to RBD(Omic) became stronger. …”
Publicado 2023
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828“…Dream-enactment behavior that emerges during episodes of rapid eye movement (REM) sleep without muscle atonia is a parasomnia known as REM sleep behavior disorder (RBD). RBD constitutes a prodromal marker of α-synucleinopathies and serves as one of the best biomarkers available to predict diseases such as Parkinson disease, multiple system atrophy and dementia with Lewy bodies. …”
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829por Trout, Jonathan, Christiansen, Taylor, Bulkley, M. Brooks, Tanner, Jared J., Sozda, Christopher N., Bowers, Dawn, Kay, Daniel B.“…We investigated cognitive functioning and self-reported sleep in early-stage PD individuals with (n = 19) or without (n = 31) probable RBD. Probable RBD was defined as >5 on the REM Sleep Behavior Disorder Screening Questionnaire. …”
Publicado 2019
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830por Nobleza, Chelsea Mae N, Siddiqui, Mariah, Shah, Parth V, Balani, Prachi, Lopez, Angel R, Khan, Safeera“…Rapid eye movement sleep behavior disorder (RBD) contributes to injury due to the alteration of the expected atonia during rapid eye movement (REM) sleep. …”
Publicado 2020
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831“…BACKGROUND: Rapid eye movement sleep behavior disorder (RBD) is associated with cognitive decline in early Parkinson’s disease (PD). …”
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832por Si, Xiao-li, Gu, Lu-yan, Song, Zhe, Zhou, Cheng, Fang, Yi, Jin, Chong-yao, Wu, Jing-jing, Gao, Ting, Guo, Tao, Guan, Xiao-jun, Xu, Xiao-jun, Yin, Xin-zhen, Yan, Ya-ping, Zhang, Min-min, Pu, Jia-li“…OBJECTIVE: To evaluate the clinical and neuroimaging significance of MRI-visible EPVS in iRBD and PD patients. METHODS: We enrolled 33 iRBD patients, 82 PD (with and without RBD) patients, and 35 healthy controls (HCs), who underwent clinical evaluation and 3.0 Tesla MRI. …”
Publicado 2020
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833por Fougeroux, Cyrielle, Goksøyr, Louise, Idorn, Manja, Soroka, Vladislav, Myeni, Sebenzile K., Dagil, Robert, Janitzek, Christoph M., Søgaard, Max, Aves, Kara-Lee, Horsted, Emma W., Erdoğan, Sayit Mahmut, Gustavsson, Tobias, Dorosz, Jerzy, Clemmensen, Stine, Fredsgaard, Laurits, Thrane, Susan, Vidal-Calvo, Elena E., Khalifé, Paul, Hulen, Thomas M., Choudhary, Swati, Theisen, Michael, Singh, Susheel K., Garcia-Senosiain, Asier, Van Oosten, Linda, Pijlman, Gorben, Hierzberger, Bettina, Domeyer, Tanja, Nalewajek, Blanka W., Strøbæk, Anette, Skrzypczak, Magdalena, Andersson, Laura F., Buus, Søren, Buus, Anette Stryhn, Christensen, Jan Pravsgaard, Dalebout, Tim J., Iversen, Kasper, Harritshøj, Lene H., Mordmüller, Benjamin, Ullum, Henrik, Reinert, Line S., de Jongh, Willem Adriaan, Kikkert, Marjolein, Paludan, Søren R., Theander, Thor G., Nielsen, Morten A., Salanti, Ali, Sander, Adam F.“…Here, we develop two capsid-like particle (CLP)-based vaccines displaying the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. RBD antigens are displayed on AP205 CLPs through a split-protein Tag/Catcher, ensuring unidirectional and high-density display of RBD. …”
Publicado 2021
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834por Davenport, Bennett J., Catala, Alexis, Weston, Stuart M., Johnson, Robert M., Ardanuy, Jeremy, Hammond, Holly L., Dillen, Carly, Frieman, Matthew B., Catalano, Carlos E., Morrison, Thomas E.“…Here, we engineered PLPs that display the receptor-binding domain (RBD) protein from SARS-CoV-2 and MERS-CoV, alone (RBD(SARS)-PLPs and RBD(MERS)-PLPs) and in combination (hCoV-RBD PLPs). …”
Publicado 2022
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835por Jiang, Xu, Pan, Yang, Zhu, Sha, Wang, Yaxi, Gu, Ruxin, Jiang, Yinyin, Shen, Bo, Zhu, Jun, Xu, Shulan, Yan, Jun, Dong, Jingde, Zhang, Wenbin, Xiao, Chaoyong, Zhang, Li“…OBJECTIVE: Patients with rapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson’s disease (PD-RBD) tend to have poor cognitive performance and faster cognitive deterioration, and the potential mechanism is still ambiguous. …”
Publicado 2022
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836por Barber, Thomas R, Muhammed, Kinan, Drew, Daniel, Bradley, Kevin M, McGowan, Daniel R, Klein, Johannes C, Manohar, Sanjay G, Hu, Michele T M, Husain, Masud“…Idiopathic rapid eye movement sleep behaviour disorder (iRBD) has now been established as an important marker of the prodromal stage of Parkinson’s disease and related synucleinopathies. …”
Publicado 2022
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837por Graham, Nancy R, Whitaker, Annalis N, Strother, Camilla A, Miles, Ashley K, Grier, Dore, McElvany, Benjamin D, Bruce, Emily A, Poynter, Matthew E, Pierce, Kristen K, Kirkpatrick, Beth D, Stapleton, Renee D, An, Gary, van den Broek‐Altenburg, Eline, Botten, Jason W, Crothers, Jessica W, Diehl, Sean A“…Anti‐RBD‐S IgG, IgM and IgA responses were simultaneously induced within 10 days after onset, with anti‐RBD‐S IgG sustained over a 5‐week period. …”
Publicado 2020
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838“…Objective: We aimed to determine (1) how stable probable RBD (pRBD) is over time and (2) whether it predicts faster PD progression. …”
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839por Laguna, Ariadna, Xicoy, Helena, Tolosa, Eduardo, Serradell, Mònica, Vilas, Dolores, Gaig, Carles, Fernández, Manel, Yanes, Oscar, Santamaria, Joan, Amigó, Núria, Iranzo, Alex, Vila, Miquel“…This allowed a prediction of the possible future clinical outcome of iRBD patients. We provide evidence of altered lipoprotein and glycosylation profiles in subgroups of iRBD patients. …”
Publicado 2021
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840por Kim, Byoung-Jun, Jeong, Hyein, Seo, Hyejun, Lee, Mi-Hyun, Shin, Hyun Mu, Kim, Bum-Joon“…In this study, we developed a novel recombinant Mycobacterium paragordonae expressing the SARS-CoV-2 receptor-binding domain (RBD) (rMpg-RBD-7) that is capable of eliciting RBD-specific immune responses in vaccinated mice. …”
Publicado 2021
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