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901por D’Este, Giada, Berra, Francesca, Carli, Giulia, Leitner, Caterina, Marelli, Sara, Zucconi, Marco, Casoni, Francesca, Ferini-Strambi, Luigi, Galbiati, Andrea“…Isolated rapid-eye-movement sleep behaviour disorder (RBD) is considered the prodromal stage of α-synucleinopathies (e.g., Parkinson’s disease and dementia with Lewy bodies); however, iRBD patients show a wide variety in the progression timing (5–15 years). …”
Publicado 2023
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902por Figorilli, Michela, Meloni, Mario, Lanza, Giuseppe, Casaglia, Elisa, Lecca, Rosamaria, Saibene, Francesca Lea, Congiu, Patrizia, Puligheddu, Monica“…Indeed, patients with isolated RBD (iRBD) have an extremely high estimated risk to develop a neurodegenerative disease after a long follow up. …”
Publicado 2023
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903por Zhang, Xuan, Ma, Li, Liang, Danqi, Song, Bingxin, Chen, Jingshan, Huang, Yaqin, Xu, Lin, Zhao, Peng, Wu, Wei, Zhang, Nan, Xue, Rong“…OBJECTIVE: To evaluate whether plasma NfL is valuable in reflecting cognitive and motor status in iRBD and PD with a premorbid history of RBD (PDRBD), and predicting disease progression in iRBD. …”
Publicado 2023
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904por Masson, Letícia Carrijo, Servian, Carolina do Prado, Jardim, Vitor Hugo, dos Anjos, Déborah, Dorta, Miriam Leandro, Batalha-Carvalho, João Victor, Moro, Ana Maria, Romão, Pedro Roosevelt Torres, Souza, Menira, Fiaccadori, Fabiola Souza, Fonseca, Simone Gonçalves“…Serum samples were quantified for anti-RBD IgG and anti-RBD IgA and anti-spike IgG by ELISA. …”
Publicado 2023
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905“…Here we characterized Dicer-2 mutants lacking either the N-terminal helicase domain or the C-terminal dsRNA-binding domain (CdsRBD) (ΔHelicase and ΔCdsRBD, respectively) in vivo and in vitro. …”
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906por Ma, Chaoran, Pavlova, Milena, Li, Junjuan, Liu, Ying, Sun, Yujie, Huang, Zhe, Wu, Shouling, Gao, Xiang“…We determined pRBD using a validated RBD questionnaire–Hong Kong in 2012. …”
Publicado 2018
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907por Chen, Meijie, Chen, Jie, Xu, Xitong, Qiao, Fangwei, Wang, Xue, Ji, Shaozhen, Gu, Zhuqin, Chhetri, Jagadish K., Chan, Piu“…Methods: In this cross-sectional study of the Beijing Longitudinal Study of Aging II (BLSA II), 4,477 subjects (≥55 years) fulfilled the inclusion criteria. pRBD was determined by the RBD Questionnaire–Hong Kong (RBDQ-HK). …”
Publicado 2020
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908por Han, Xianhua, Wu, Ping, Alberts, Ian, Zhou, Hucheng, Yu, Huan, Bargiotas, Panagiotis, Yakushev, Igor, Wang, Jian, Höglinger, Guenter, Förster, Stefan, Bassetti, Claudio, Oertel, Wolfgang, Schwaiger, Markus, Huang, Sung-Cheng, Cumming, Paul, Rominger, Axel, Jiang, Jiehui, Zuo, Chuantao, Shi, Kuangyu“…OBJECTIVE: Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) is a prodromal stage of synucleinopathies such as Parkinson’s disease (PD). …”
Publicado 2020
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909por Chahine, Lana M., Brumm, Michael C., Caspell‐Garcia, Chelsea, Oertel, Wolfgang, Mollenhauer, Brit, Amara, Amy, Fernandez‐Arcos, Ana, Tolosa, Eduardo, Simonet, Cristina, Hogl, Birgit, Videnovic, Aleksandar, Hutten, Samantha J., Tanner, Caroline, Weintraub, Daniel, Burghardt, Elliot, Coffey, Christopher, Cho, Hyunkeun R., Kieburtz, Karl, Poston, Kathleen L., Merchant, Kalpana, Galasko, Douglas, Foroud, Tatiana, Siderowf, Andrew, Marek, Kenneth, Simuni, Tanya, Iranzo, Alex“…INTRODUCTION: Individuals with idiopathic rapid eye movement sleep behavior disorder (iRBD) are at high risk for a clinical diagnosis of an α‐synucleinopathy (aSN). …”
Publicado 2020
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910“…Immunoblotting showed that rSA11/-fNTD, -fRBD, -fExRBD, and -fCR viruses expressed S products of expected size, with fExRBD expressed at highest levels. …”
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911por Valomon, Amandine, Riedner, Brady A., Jones, Stephanie G., Nakamura, Keith P., Tononi, Giulio, Plante, David T., Benca, Ruth M., Boly, Melanie“…Rapid eye movement (REM) sleep behavior disorder (RBD) is characterized by disrupting motor enactments during REM sleep, but also cognitive impairments across several domains. …”
Publicado 2021
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912por Rosadas, Carolina, Khan, Maryam, Parker, Eleanor, Marchesin, Federica, Katsanovskaja, Ksenia, Sureda-Vives, Macià, Fernandez, Natalia, Randell, Paul, Harvey, Ruth, Lilley, Alice, Harris, Benjamin H.L., Zuhair, Mohamed, Fertleman, Michael, Ijaz, Samreen, Dicks, Steve, Short, Charlotte-Eve, Quinlan, Rachael, Taylor, Graham P., Hu, Kai, McKay, Paul, Rosa, Annachiara, Roustan, Chloe, Zuckerman, Mark, El Bouzidi, Kate, Cooke, Graham, Flower, Barnaby, Moshe, Maya, Elliott, Paul, Spencer, Alexandra J., Lambe, Teresa, Gilbert, Sarah C., Kingston, Hugh, Baillie, J. Kenneth, Openshaw, Peter J.M., Semple, Malcolm G., Cherepanov, Peter, McClure, Myra O., Tedder, Richard S.“…A double antigen binding assay (DABA), providing the most sensitive format has been exploited in a novel hybrid manner employing a solid-phase S1 preferentially presenting RBD, coupled with a labelled RBD conjugate, used in a two-step sequential assay for detection and measurement of antibody to RBD (anti-RBD). …”
Publicado 2022
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913por Luca, Antonina, Cicero, Calogero Edoardo, Giuliano, Loretta, Sgroi, Riccardo, Vancheri, Edoardo, Terravecchia, Claudio, Squillaci, Raffaele, Rascunà, Cristina, Donzuso, Giulia, Mostile, Giovanni, Sciacca, Giorgia, Zappia, Mario, Nicoletti, Alessandra“…Rapid eye movement sleep behavior disorder (RBD) is a common prodromic non-motor symptom of Parkinson’s disease (PD). …”
Publicado 2022
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914“…Delta variant RBD contains two novel mutations L452R and T478K. …”
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915“…BACKGROUND: We investigated the evolutionary relationships, mutations, antigenic epitopes, and structural dynamics of the receptor-binding domain (RBD) of SARS-CoV-2, Omicron and other recently evolved variants. …”
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916“…RBD vaccination without CS formulation resulted in minimal anti-RBD responses. …”
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917por Nelson-Sathi, Shijulal, Umasankar, P. K., Sreekumar, E., Nair, R. Radhakrishnan, Joseph, Iype, Nori, Sai Ravi Chandra, Philip, Jamiema Sara, Prasad, Roshny, Navyasree, K. V., Ramesh, Shikha, Pillai, Heera, Ghosh, Sanu, Santosh Kumar, T. R., Pillai, M. Radhakrishna“…RBD has been shown to mutate frequently during pandemic. …”
Publicado 2022
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918por Levendowski, Daniel J, Neylan, Thomas C, Lee-Iannotti, Joyce K, Timm, Paul C, Guevarra, Cyrus, Angel, Elise, Shprecher, David, Mazeika, Gandis, Walsh, Christine M, Boeve, Bradley F, St Louis, Erik K“…PURPOSE: This study aimed to establish the diagnostic accuracy of a previously validated sleep staging system in patients with probable isolated REM sleep behavior disorder (iRBD), and to compare physicians’ diagnoses of iRBD based on REM sleep without atonia (RSWA) to non-REM hypertonia (NRH), a sleep measure independently associated with Parkinsonian spectrum disorders. …”
Publicado 2023
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919por Barh, Debmalya, Tiwari, Sandeep, Silva Andrade, Bruno, Giovanetti, Marta, Almeida Costa, Eduardo, Kumavath, Ranjith, Ghosh, Preetam, Góes-Neto, Aristóteles, Carlos Junior Alcantara, Luiz, Azevedo, Vasco“…Second, peptides from five antibacterial peptide databases that block nCoV-RBD are identified; finally, a chimeric peptide design approach is used to design peptides that can bind to key nCoV-RBD residues. …”
Publicado 2020
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920por Slattery, Samuel S., Giguere, Daniel J., Stuckless, Emily E., Shrestha, Arina, Briere, Lee-Ann K., Galbraith, Alexa, Reaume, Stephen, Boyko, Xenia, Say, Henry H., Browne, Tyler S., Frederick, Mallory I., Lant, Jeremy T., Heinemann, Ilka U., O’Donoghue, Patrick, Dsouza, Liann, Martin, Steven, Howard, Peter, Jedeszko, Christopher, Ali, Kinza, Styba, Garth, Flatley, Martin, Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.“…The RBD was purified from whole cell extracts (algae-RBD) with yield compromised by the finding that 90–95% of expressed RBD lacked the genetically encoded C-terminal 6X-histidine tag. …”
Publicado 2022
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