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921por Morén, C., González-Casacuberta, Í., Navarro-Otano, J., Juárez-Flores, D., Vilas, D., Garrabou, G., Milisenda, J. C., Pont-Sunyer, C., Catalán-García, M., Guitart-Mampel, M., Tobías, E., Cardellach, F., Valldeoriola, F., Iranzo, A., Tolosa, E.“…OBJECTIVE: To determine potential mitochondrial and oxidative alterations in colon biopsies from idiopathic REM sleep behavior disorder (iRBD) and Parkinson's disease (PD) subjects. METHODS: Colonic biopsies from 7 iRBD subjects, 9 subjects with clinically diagnosed PD, and 9 healthy controls were homogenized in 5% w/v mannitol. …”
Publicado 2017
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922“…OBJECTIVE: Rapid eye movement sleep behavior disorder (RBD) is characterized by dream enactment and loss of muscle atonia during rapid eye movement sleep. …”
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923por Huang, Canping, Qi, Jianxun, Lu, Guangwen, Wang, Qihui, Yuan, Yuan, Wu, Ying, Zhang, Yanfang, Yan, Jinghua, Gao, George F.“…In this study, the putative S RBD of BatCoV HKU9 (HKU9-RBD), which is homologous to other betaCoV RBDs that have been structurally and functionally defined, was characterized via a series of biophysical and crystallographic methods. …”
Publicado 2016
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924por Tiwari, Vishvanath“…Spike protein contains a receptor-binding domain (RBD) that recognizes hACE-2. In the present study, we are reporting a de novo designed novel hybrid antiviral ‘VTAR-01’ molecule that binds at the interface of RBD-hACE2 interaction. …”
Publicado 2020
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925por Miller, Christina J., McGinnis, Jennifer E., Martinez, Michael J., Wang, Guangli, Zhou, Jian, Simmons, Erica, Amet, Tohti, Abdeen, Sanofar J., Van Huysse, James W., Bowsher, Ronald R., Kay, Brian K.“…Three of the four monobodies bound selectively to the RBD of SARS-CoV-2, with the fourth monobody showing slight cross-reactivity to the RBD of SARS-CoV-1 virus. …”
Publicado 2021
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926por Zimansky, Larissa, Muntean, Maria‐Lucia, Leha, Andreas, Mollenhauer, Brit, Trenkwalder, Claudia, Sixel‐Döring, Friederike“…BACKGROUND: Rapid eye movement (REM) sleep behavior disorder (RBD) is associated with neurodegenerative diseases; however, few longitudinal studies assess the individual evolution of RBD and REM sleep without atonia (RWA) in Parkinson's disease (PD). …”
Publicado 2021
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927“…Increasing evidence suggests that patients with comorbid PD and RBD (PD-RBD) are more likely to develop cognitive impairment (CI) than those with isolated PD; however, the predictors of CI in PD-RBD patients are not well understood. …”
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928por Li, Daixi, Wang, Cheng, Wang, Shaobo, Mehmood, Aamir, Gu, Jiang, Cheng, Xin, Chen, Peiqin, Qiu, JingFei, Zhao, Jinghong, Wang, Junping, Wei, Dongqing“…Considering the binding free energies of AVPs to RBD, cyanovirin-N (CV-N) showed the strongest RBD binding affinity among 52 AVPs. …”
Publicado 2021
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929“…Accordingly, mAb1 failed to inhibit the ACE2-RBD interaction while mAb2 inhibited the ACE2-RBD interactions for all RBD mutants, except mutant E484K, which only displayed partial blocking.…”
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930“…In the presence of graphene and phosphorene, the RBD has lower stability because due to the strong interactions between RBD and these nanostructures. …”
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931“…BACKGROUND AND PURPOSE: Rapid eye movement (REM) Rapid eye movement sleep behavior disorder (RBD) is a common non-motor symptom of PD. However, the association between the SNCA rs3910105 genotype and RBD in Parkinson’s disease (PD) remains unclear. …”
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932“…Among the novel mutations distinguishing SARS-CoV-2 from similar respiratory coronaviruses is a K403R substitution in the receptor-binding domain (RBD) of the viral spike (S) protein within its S1 region. …”
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933por Olivera-Ugarte, Santa-Mariela, Bolduc, Marilène, Laliberté-Gagné, Marie-Ève, Blanchette, Léa-Jeanne, Garneau, Caroline, Fillion, Maude, Savard, Pierre, Dubuc, Isabelle, Flamand, Louis, Farnòs, Omar, Xu, Xingge, Kamen, Amine, Gilbert, Mégan, Rabezanahary, Henintsoa, Scarrone, Martina, Couture, Christian, Baz, Mariana, Leclerc, Denis“…A vaccine candidate to SARS-CoV-2 was constructed by coupling the viral receptor binding domain (RBD) to the surface of the papaya mosaic virus (PapMV) nanoparticle (nano) to generate the RBD-PapMV vaccine. …”
Publicado 2022
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934por Geropeppa, Maria, Papadatou, Ioanna, Sarantis, Panagiotis, Tzanoudaki, Marianna, Ntanasis-Stathopoulos, Ioannis, Bagratuni, Tina, Terpos, Evangelos, Spoulou, Vana“…In this study, we found that dual BNT162b2 vaccination significantly increased both total RBD-specific and memory RBD-specific B cells and neutralizing antibodies. …”
Publicado 2023
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935por Pereira‐Acácio, Amaury, Veloso‐Santos, João P. M., Alves‐Bezerra, Danilo, Costa‐Sarmento, Glória, Muzi‐Filho, Humberto, Vieyra, Adalberto“…The drug normalized the decreased plasma Na(+) concentration in RBD rats, increased urinary volume in RBD but not in CTRL, and decreased and increased urinary Na(+) concentration in the RBD and CTRL groups, respectively. …”
Publicado 2023
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936por Steimer, Lenz, Wurm, Jan Philip, Linden, Martin H., Rudolph, Markus G., Wöhnert, Jens, Klostermeier, Dagmar“…A crystal structure of the RBD in complex with a single-stranded RNA resolves the RNA–protein interactions in the RBD core region around helix α1. …”
Publicado 2013
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937por Tribl, Gotthard G., Trindade, Mateus C., Schredl, Michael, Pires, Joana, Reinhard, Iris, Bittencourt, Thais, Lorenzi-Filho, Geraldo, Alves, Rosana Cardoso, de Andrade, Daniel Ciampi, Fonoff, Erich T., Bor-Seng-Shu, Edson, Machado, Alexandre A., Teixeira, Manoel J., Barbosa, Egberto R.“…Violent dream content and its acting out during rapid eye movement sleep are considered distinctive for rapid eye movement sleep behaviour disorder (RBD). This study reports first quantitative data on dreaming in a cohort of patients with treated Wilson's disease (WD) and in patients with WD with RBD. …”
Publicado 2016
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938“…This study aimed to evaluate the clinical variations in patients with Parkinson’s disease (PD) with (PDRBD) or without REM sleep behaviour disorder (RBD) (Non-RBD), and PDRBD patients were classified into Confirmed-RBD (definite diagnosis with polysomnography, PSG) and Probable-RBD (without PSG re-confirmation). …”
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939por Perkins, Julia E., Janzen, Annette, Bernhard, Felix P., Wilhelm, Karén, Brien, Donald C., Huang, Jeff, Coe, Brian C., Vadasz, David, Mayer, Geert, Munoz, Douglas P., Oertel, Wolfgang H.“…RESULTS: RBD patients did not have significantly different saccadic behavior compared to CTRL, but PD patients differed from CTRL and RBD. …”
Publicado 2021
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940por Shin, Hye Jin, Ku, Keun Bon, Kim, Hae Soo, Moon, Hyun Woo, Jeong, Gi Uk, Hwang, Insu, Yoon, Gun Young, Lee, Sunhee, Lee, Sumin, Ahn, Dae-Gyun, Kim, Kyun-Do, Kwon, Young-Chan, Kim, Bum-Tae, Kim, Seong-Jun, Kim, Chonsaeng“…To evaluate the potential antiviral activity of recombinant SARS-CoV-2 RBD proteins, we determined the RBD residues of SARS-CoV-2 using a homology search with RBD of SARS-CoV. …”
Publicado 2021
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