-
1081“…To bind to ACE2, the RBD must transition from the closed-form to the open-form configuration. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1082por Fang, Huey-Jen, Chen, Yong-Zhong, Li, Mai Suan, Wu, Ming-Chya, Chang, Chun-Ling, Chang, Chung-ke, Hsu, Yen-lan, Huang, Tai-huang, Chen, Hueih-Min, Tsong, Tian-Yow, Hu, Chin-Kun“…Differential scanning calorimetry, circular dichroism spectroscopy, nuclear magnetic resonance spectroscopy, and numerical simulations were used to study the thermostability of the N-terminal RNA-binding domain (RBD) of the SARS-CoV nucleocapsid protein. The transition temperature of the RBD in a mixing buffer, composed of glycine, sodium acetate, and sodium phosphate with 100 mM sodium chloride, at pH 6.8, determined by differential scanning calorimetry and circular dichroism, is 48.74°C. …”
Publicado 2009
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1083“…We thus suggest that the anti-RBD/anti-N antibody ratio may serve as an indicator of the disease severity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1084por Samuelsson, Ebba, Mirgorodskaya, Ekaterina, Nyström, Kristina, Bäckström, Malin, Liljeqvist, Jan-Åke, Nordén, Rickard“…[Image: see text] The receptor-binding domain (RBD) of the SARS-CoV-2 spike protein is a conserved domain and a target for neutralizing antibodies. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1085por Kang, Hyangju, Kim, Daniel, Min, Kyungmin, Park, Minhee, Kim, Seok-Hyun, Sohn, Eun-Ju, Choi, Bo-Hwa, Hwang, Inhwan“…Antibodies in serum inhibited interaction of recombinant human angiotensin-converting enzyme 2 with RBD of the Omicron variant, but not RBD of other variants. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1086por Xu, Huifang, Wang, Tiantian, Sun, Peng, Hou, Xuchen, Gong, Xin, Zhang, Bin, Wu, Jun, Liu, Bo“…These results suggested that a bivalent vaccine of RBD-Beta and RBD-wild type could be a possible broad-spectrum vaccination strategy.…”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1087“…First, nine monoclonal antibodies (MAbs) against the RBD or S1 were generated; of these, one RBD-specific MAb, 22.9-1, was selected for its broad RBD-binding abilities and neutralizing activities against SARS-CoV-2 variants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1088por Boumaiza, Mohamed, Chaabene, Ameni, Akrouti, Ines, Ben Zakour, Meriem, Askri, Hana, Salhi, Said, Ben Hamouda, Wafa, Marzouki, Soumaya, Benabdessalem, Chaouki, Ben Ahmed, Melika, Trabelsi, Khaled, Rourou, Samia“…For this purpose, the commonly used antigen, receptor-binding domain (RBD) of spike S1 protein (S1RBD), was produced using the baculovirus expression vector system (BEVS). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1089Publicado 1992“…We refer to this configuration, which is also found in the hnRNP A/B proteins of vertebrates, as 2 x RBD-Gly. The sequences of the D. melanogaster hnRNP proteins help define both highly conserved and variable amino acids within each RBD and support the suggestion that each RBD in multiple RBD-containing proteins has been conserved independently and has a different function. …”
Enlace del recurso
Enlace del recurso
Texto -
1090por Bale, Shridhar, Julien, Jean-Philippe, Bornholdt, Zachary A., Kimberlin, Christopher R., Halfmann, Peter, Zandonatti, Michelle A., Kunert, John, Kroon, Gerard J. A., Kawaoka, Yoshihiro, MacRae, Ian J., Wilson, Ian A., Saphire, Erica Ollmann“…The C-terminal double-stranded (ds)RNA-binding domain (RBD) of VP35 has been implicated in interferon antagonism and immune evasion. …”
Publicado 2012
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1091por Li, Yan, Wan, Yuhua, Liu, Peipei, Zhao, Jincun, Lu, Guangwen, Qi, Jianxun, Wang, Qihui, Lu, Xuancheng, Wu, Ying, Liu, Wenjun, Zhang, Buchang, Yuen, Kwok-Yung, Perlman, Stanley, Gao, George F, Yan, Jinghua“…We further investigated their mechanisms of neutralization by crystallizing the complex between the Fab fragments and the RBD, and solved the structure of the 4C2 Fab/MERS-RBD complex. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1092por Kruse, Janis, Meier, Doreen, Zenk, Fides, Rehders, Maren, Nellen, Wolfgang, Hammann, Christian“…The complex is composed of the Dicer DrnB and the dsRBD (double-stranded RNA binding domain) containing protein RbdB. …”
Publicado 2016
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1093por Travers, Timothy, López, Cesar A., Van, Que N., Neale, Chris, Tonelli, Marco, Stephen, Andrew G., Gnanakaran, S.“…Activation of RAF kinase involves the association of its RAS-binding domain (RBD) and cysteine-rich domain (CRD) with membrane-anchored RAS. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1094por Chahine, L. M., Iranzo, A., Fernández-Arcos, A., Simuni, T., Seedorff, N., Caspell-Garcia, C., Amara, A. W., Comella, C., Högl, B., Hamilton, J., Marek, K., Mayer, G., Mollenhauer, B., Postuma, R., Tolosa, E., Trenkwalder, C., Videnovic, A., Oertel, W.“…REM sleep behavior disorder (RBD) is strongly associated with development of Parkinson’s Disease and other α-synuclein-related disorders. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1095por Xiao, Fulong, Zhang, Jun, Wang, Waner, Wang, Xuehua, Zhang, Wei, Xu, Liyue, Han, Fang“…Here we reported a patient with a history of Behcet’s disease and Sjogren’s syndrome in which REM sleep behavior disorder (RBD) was then detected by polysomnographic (PSG) monitoring. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1096por Baldelli, Luca, Addimanda, Olga, Burattini, Marco, Chiaro, Giacomo, Brusi, Veronica, Pignotti, Elettra, Meliconi, Riccardo, Provini, Federica“…OBJECTIVES: To investigate the prevalence of REM sleep behavior disorder (RBD) in patients with inflammatory arthritis (IA) to ascertain if RBD could be an internal red flag signaling a fluctuating state of inflammation based on the theory of “protoconsciousness”. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1097por Li, Entao, Chi, Hang, Huang, Pei, Yan, Feihu, Zhang, Ying, Liu, Chuanyu, Wang, Zhenshan, Li, Guohua, Zhang, Shengnan, Mo, Ruo, Jin, Hongli, Wang, Hualei, Feng, Na, Wang, Jianzhong, Bi, Yuhai, Wang, Tiecheng, Sun, Weiyang, Gao, Yuwei, Zhao, Yongkun, Yang, Songtao, Xia, Xianzhu“…The designs included different numbers of lysin motif (LysM) repeats in the PAs linked by linkers (RBD-linker-PA2 (RLP(2)), RBD-linker-PA3 (RLP(3)) and RBD-PA3 (RP(3))), and three LysM repeats and a linker in the fusion proteins increased the binding activity to the RBD. …”
Publicado 2019
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1098por Cochen De Cock, Valérie, de Verbizier, Delphine, Picot, Marie Christine, Damm, Loïc, Abril, Beatriz, Galtier, Florence, Driss, Valérie, Lebrun, Cindy, Pageot, Nicolas, Giordano, Aurélie, Gonzalvez, Chloé, Homeyer, Pascale, Carlander, Bertrand, Castelnovo, Giovanni, Geny, Christian, Bardy, Benoit, Dalla Bella, Simone“…OBJECTIVE: We aimed to identify timing distortions in production and perception of rhythmic events in patients with idiopathic REM sleep behavior disorder (iRBD) as early markers of Parkinson's disease (PD). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1099por He, Yuxian, Zhou, Yusen, Liu, Shuwen, Kou, Zhihua, Li, Wenhui, Farzan, Michael, Jiang, Shibo“…Here we show that a recombinant fusion protein (designated RBD-Fc) containing 193-amino acid RBD (residues 318–510) and a human IgG1 Fc fragment can induce highly potent antibody responses in the immunized rabbits. …”
Publicado 2004
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1100por Okba, Nisreen M. A., Widjaja, Ivy, van Dieren, Brenda, Aebischer, Andrea, van Amerongen, Geert, de Waal, Leon, Stittelaar, Koert J., Schipper, Debby, Martina, Byron, van den Brand, Judith M. A., Beer, Martin, Bosch, Berend-Jan, Haagmans, Bart L.“…Using a “plug-and-display” SpyTag/SpyCatcher system, we coupled RBD to lumazine synthase (LS) particles producing multimeric RBD-presenting particles (RBD-LS). …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto