-
1141por Sauer, J., Beushausen, K., Keil, J., Ruhl, L., Kühne, J., Schael, M., Welte, T., Haverich, A., Gottlieb, J., Niehaus, A., Falk, C.S.“…The same applies for S2 vs S1 (p < 0.0001) and RBD vs S1 (p = 0.0018) in the HTx cohort. Comparing the MFI of S2 vs RBD, the levels of domain-specific IgG were higher for S2 than RBD in both LTx (p < 0.0001) and HTx patients (p = 0.0914). …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1142por Li, Wenping, Wang, Fulian, Li, Yu, Yan, Lei, Liu, Lili, Zhu, Wei, Ma, Peixiang, Shi, Xiaojie, Yang, Guang“…The majority of neutralizing antibodies (NAbs) against SARS-CoV-2 recognize the receptor-binding domain (RBD) of the spike (S) protein. As an escaping strategy, the RBD of the virus is highly variable, evolving mutations to thwart a natural immune response or vaccination. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1143por Timm, Morgan R., Tamadonfar, Kevin O., Nye, Taylor M., Pinkner, Jerome S., Dodson, Karen W., Ellebedy, Ali H., Hultgren, Scott J.“…We developed a protein subunit vaccine against Abp1D(RBD) and Abp2D(RBD) and showed that vaccination significantly reduced bladder bacterial titers in a mouse model of CAUTI. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1144por Mueller, Geoffrey A, Miller, Matthew T, DeRose, Eugene F, Ghosh, Mahua, London, Robert E, Hall, Traci M Tanaka“…RESULTS: We report here the solution structure of the dsRBD from Drosha (Drosha-dsRBD). The αβββα fold is similar to other dsRBD structures. …”
Publicado 2010
Enlace del recurso
Enlace del recurso
Enlace del recurso
Texto -
1145por Lacerte, Annie, Chouinard, Sylvain, Jodoin, Nicolas, Bernard, Geneviève, Rouleau, Guy A., Panisset, Michel“…Using a screening questionnaire for RBD, 43.5% of ET patients are possibly suffering from RBD, whereas in the general population prevalence is estimated to be 0.5%. …”
Publicado 2014
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1146por Tan, Lu, Zhou, Junying, Yang, Linghui, Ren, Rong, Zhang, Ye, Li, Taomei, Tang, Xiangdong“…With this case report, we found an association between typical RBD and duloxetine, a serotonin-noradrenaline reuptake inhibitor. …”
Publicado 2017
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1147por Du, Yanli, Jiang, Jiajun, Ng, Chee H., Wu, Lingling, Zhang, Peifen, Xi, Caixi, Lai, Jianbo, Xu, Yi, Hu, Shaohua, Wang, Zheng“…The pharmacotherapy options for treating RBD are limited and the use of antidepressants remains controversial. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1148por Greaney, Allison J., Starr, Tyler N., Gilchuk, Pavlo, Zost, Seth J., Binshtein, Elad, Loes, Andrea N., Hilton, Sarah K., Huddleston, John, Eguia, Rachel, Crawford, Katharine H.D., Dingens, Adam S., Nargi, Rachel S., Sutton, Rachel E., Suryadevara, Naveenchandra, Rothlauf, Paul W., Liu, Zhuoming, Whelan, Sean P.J., Carnahan, Robert H., Crowe, James E., Bloom, Jesse D.“…Antibodies targeting the SARS-CoV-2 spike receptor-binding domain (RBD) are being developed as therapeutics and make a major contribution to the neutralizing antibody response elicited by infection. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1149por Mastrangelo, Peter, Chin, Allysia A., Tan, Stephanie, Jeon, Amy H., Ackerley, Cameron A., Siu, Karen K., Lee, Jeffrey E., Hegele, Richard G.“…Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact with RSV are not known. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1150“…We show residues in the RBD of SARS-CoV-2 that were mutated from SARS-CoV, collectively help make the RBD anchor much stronger to the N-terminal part of ACE2 than the corresponding residues on RBD of SARS-CoV. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1151por Díaz-Salinas, Marco A, Li, Qi, Ejemel, Monir, Yurkovetskiy, Leonid, Luban, Jeremy, Shen, Kuang, Wang, Yang, Munro, James B“…This interaction is mediated by the receptor-binding domain (RBD) of the viral spike (S) glycoprotein. Structural and dynamic data have shown that S can adopt multiple conformations, which controls the exposure of the ACE2-binding site in the RBD. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1152por Peng, Pai, Feng, Chengqian, Hu, Jie, He, Changlong, Deng, Haijun, Fan, Qinghong, Xiang, Jin, Tang, Guofang, Jiang, Meng-ling, Hu, Fengyu, Li, Feng, Wang, Kai, Tang, Ni, Tang, Xiao-ping, Huang, Ailong“…By contrast, a heterologous Omicron-RBD booster following two doses of WT-RBD immunization increased the NAb titers against Omicron by 9-folds than the homologous WT-RBD booster. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1153“…These mutations have variable effects on the RBD’s affinity for human angiotensin-converting enzyme 2 (ACE2), but they all enhance the RBD’s affinity for mouse ACE2. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1154por Fitriah, Munawaroh, Putri, Aditea Etnawati, Semedi, Bambang Pujo, Atika, Atika, Tambunan, Betty Agustina“…RESULTS: The value of participant’s s-RBD IgG before CPT was 91.49 (0.43–3074.73) AU/mL and the 7th day post-CPT, s-RBD IgG value of 1169.79 (6.48–5577.91) AU/mL (p <0.001). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1155por Bobik, T. V., Kostin, N. N., Skryabin, G. A., Tsabai, P. N., Simonova, M. A., Knorre, V. D., Stratienko, O. N., Aleshenko, N. L., Vorobiev, I. I., Khurs, E. N., Mokrushina, Yu. A., Smirnov, I. V., Alekhin, A. I., Nikitin, A. E., Gabibov, A. G.“…These antigens were produced in the prokaryotic E. coli system. Recombinant RBD produced in the eukaryotic CHO system (RBD CHO) was used as an antigen representing conformational RBD epitopes. …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1156por Ha, Binh, Jadhao, Samadhan, Hussaini, Laila, Gibson, Theda, Stephens, Kathy, Salazar, Luis, Ciric, Caroline, Taylor, Meg, Rouphael, Nadine, Edupuganti, Srilatha, Rostad, Christina A., Tompkins, S. Mark, Anderson, Evan J., Anderson, Larry J.“…The companion indirect IgG ELISAs were positive for S in 89% of the 55 serum samples, RBD in 78%, and N in 85%. While the specificities for IgM RBD, S, and N ELISAs and IgG S and RBD ELISAs were 97% to 100%, the specificity of the N IgG ELISA was lower (89%). …”
Publicado 2021
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1157por Zhang, Lei, Yang, Jiaqing, Lai, Changchun, Wan, Li, Xiong, Shilong, Kong, Weiya, Liu, Zijian, Yu, Pei, Chen, Mingxiao, Mai, Weikang, Khan, Shahzad Akbar, Deng, Min, Chen, Lu, Lei, Yu, Zhou, Qiang, Yu, Nan, Li, Pingchao, Chen, Zheng, Ji, Tianxing“…However, the anti-Delta-RBD-IgG and anti-Omicron-RBD-IgG titers were significantly lower than anti-Ancestral-RBD-IgG titer in KTRs and HVs after the third dose. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1158por Yu, Eric, Krohn, Lynne, Ruskey, Jennifer A., Asayesh, Farnaz, Spiegelman, Dan, Shah, Zalak, Chia, Ruth, Arnulf, Isabelle, Hu, Michele T.M., Montplaisir, Jacques Y., Gagnon, Jean-François, Desautels, Alex, Dauvilliers, Yves, Gigli, Gian Luigi, Valente, Mariarosaria, Janes, Francesco, Bernardini, Andrea, Högl, Birgit, Stefani, Ambra, Ibrahim, Abubaker, Heidbreder, Anna, Sonka, Karel, Dusek, Petr, Kemlink, David, Oertel, Wolfgang, Janzen, Annette, Plazzi, Giuseppe, Antelmi, Elena, Figorilli, Michela, Puligheddu, Monica, Mollenhauer, Brit, Trenkwalder, Claudia, Sixel-Döring, Friederike, De Cock, Valérie Cochen, Ferini-Strambi, Luigi, Dijkstra, Femke, Viaene, Mineke, Abril, Beatriz, Boeve, Bradley F., Rouleau, Guy A., Postuma, Ronald B., Scholz, Sonja W., Gan-Or, Ziv“…BACKGROUND AND OBJECTIVES: Isolated/idiopathic REM sleep behavior disorder (iRBD) and Lewy body dementia (LBD) are synucleinopathies that have partial genetic overlap with Parkinson’s disease (PD). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1159“…Using rolling circle amplification (RCA) and two different ways of signal readout, we developed analytical methods to detect the receptor-binding domain (RBD) of SARS-CoV-2 spike protein (S protein). We modified streptavidin-coated magnetic beads with an aptamer of RBD through a biotin-tagged complementary DNA strand (biotin-cDNA). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1160por Nepozitek, Jiri, Varga, Zsoka, Dostalova, Simona, Perinova, Pavla, Keller, Jiri, Robinson, Simon, Ibarburu, Veronika, Prihodova, Iva, Bezdicek, Ondrej, Ruzicka, Evzen, Sonka, Karel, Dusek, Petr“…REM sleep without atonia (RWA) is the hallmark of isolated REM sleep behavior disorder (iRBD) and is caused by neurodegeneration of brainstem structures. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto