Mostrando 1,281 - 1,300 Resultados de 5,191 Para Buscar '"RBD"', tiempo de consulta: 0.43s Limitar resultados
  1. 1281
    “…Peptide A2- or RBD-containing recombinant peptides linked to an enhanced green fluorescence protein (EGFP) were prepared by expression in Escherichia coli. …”
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    Neuron-recognizable characteristics of peptides recombined using a neuronal binding domain of botulinum neurotoxin
  2. 1282
    “…The safety, anti-receptor binding domain IgG (anti-RBD-IgG) and anti-spike-IgG responses, and RBD-specific memory B cell (MBC) responses were evaluated. …”
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    Safety and immunogenicity of inactivated SARS-CoV-2 vaccines in people living with HIV
  3. 1283
    “…No significant correlation was observed between the levels of anti-RBD IgG and sex or age of the vaccinated individuals. …”
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    BNT162b2, mRNA-1273, and Sputnik V Vaccines Induce Comparable Immune Responses on a Par With Severe Course of COVID-19
  4. 1284
    “…This study aims to discover novel peptide inhibitors against SARS-CoV-2 entry using computational approaches. The RBD binding domain of ACE2 was extracted and docked against the RBD. …”
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    Inhibition of SARS-CoV-2 pathogenesis by potent peptides designed by the mutation of ACE2 binding region
  5. 1285
    “…METHODS: SARS-CoV-2 recombinant protein antigens, including truncated spike protein (SS1, lacking the N-terminal domain of S1), receptor-binding domain (RBD), and nucleoprotein (N) were used. Immunization program was performed via injection of RBD, SS1 +RBD, and SS1 +N along with different adjuvants, Alum, AS03, and Montanide at doses of 0, 40, 80, and 120 μg at three-time points in mice, rabbits, and primates. …”
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    Preclinical study of formulated recombinant nucleocapsid protein, the receptor binding domain of the spike protein, and truncated spike (S1) protein as vaccine candidates against COVID-19 in animal models
  6. 1286
    “…OBJECTIVE: To describe general treatment plans of RBD patients and evaluate the use of peri‐procedural hemostatic therapy. …”
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    Treatment of patients with rare bleeding disorders in the Netherlands: Real‐life data from the RBiN study
  7. 1287
    “…Here we use in vitro evolution to seek mutations in SARS-CoV-2 receptor binding domain (RBD) that would substantially increase binding to ACE2. …”
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    In vitro evolution predicts emerging SARS-CoV-2 mutations with high affinity for ACE2 and cross-species binding
  8. 1288
    “…Prevalence of EDS, RBD, and RLS in PD patients was higher compared to that reported in studies during the pre-COVID-19 times. …”
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    Sleep Disorders in Patients with Parkinson's Disease during COVID-19 Pandemic: A Case–Control Study
  9. 1289
    “…Subsequently, 174 subjects (72 without RBD and 102 with RBD) were analysed with RBDtector to show the algorithm’s applicability. …”
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    RBDtector: an open-source software to detect REM sleep without atonia according to visual scoring criteria
  10. 1290
    “…We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited upon natural infection and vaccination and showed that they recognize an immunogenic patch on the internal surface of the core RBD, which faces inwards and is hidden in the “down” state. …”
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    Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2
  11. 1291
    “…Notably, the epitopes of these five K-RBD-mAbs are overlapping and localized around Y453 and F486 of the spike protein receptor binding domain (RBD). …”
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    Broadly neutralizing antibodies against Omicron variants of SARS-CoV-2 derived from mRNA-lipid nanoparticle-immunized mice
  12. 1292
    “…Isolated rapid eye movement sleep behavior disorder (iRBD) is a sleep disorder characterized by dream enactment behavior without any neurological disease and is frequently accompanied by cognitive dysfunction. …”
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    Spatiotemporal characteristics of cortical activities of REM sleep behavior disorder revealed by explainable machine learning using 3D convolutional neural network
  13. 1293
    “…One aptamer interferes with the binding of ACE2 by blocking the ACE2-binding site in RBD, and the other aptamer allosterically inhibits ACE2 by binding to a distinct face of RBD. …”
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    Structure-Guided Development of Bivalent Aptamers Blocking SARS-CoV-2 Infection
  14. 1294
    “…The RNA-binding domain (RBD) of hnRNP U was previously mapped to an RGG/RG element within its disordered C-terminal region, but little is understood about its binding mode and potential for selective RNA recognition. …”
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    The RNA-binding domain of hnRNP U extends beyond the RGG/RG motifs
  15. 1295
    “…Alterations in brain iron suggest neurodegeneration; however, the literature on striatal iron has been inconsistent in PD and scant in RBD. Toward clarifying pathophysiological changes in PD and RBD, and uncovering possible biomarkers, we imaged 26 early-stage PD patients, 16 RBD patients, and 39 age-matched healthy controls with 3 T MRI. …”
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    Subregional analysis of striatum iron in Parkinson’s disease and rapid eye movement sleep behaviour disorder
  16. 1296
    “…To improve the broad-spectrum antiviral activity of the candidate vaccine, Delta RBD proteins were mixed with BA.2 RBD proteins at a ratio of 1:1 and then combined with two adjuvants—Al(OH)(3) and CpG—to prepare a bivalent vaccine. …”
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    A Delta–Omicron Bivalent Subunit Vaccine Elicited Antibody Responses in Mice against Both Ancestral and Variant Strains of SARS-CoV-2
  17. 1297
    “…The MERS-27 epitope in the RBD overlaps with the binding site of the MERS-CoV receptor DPP4. …”
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    Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27
  18. 1298
    “…We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD. We demonstrate why this is the case using bacteria-expressed proteins: the DHX30N-NS1 RBD interaction in vitro requires the presence of a dsRNA platform that binds both NS1 RBD and DHX30N. …”
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    A double-stranded RNA platform is required for the interaction between a host restriction factor and the NS1 protein of influenza A virus
  19. 1299
    “…Both S and the RBD are highly immunogenic and both have been found to elicit neutralizing antibodies. …”
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    Structural Insights into Immune Recognition of the Severe Acute Respiratory Syndrome Coronavirus S Protein Receptor Binding Domain
  20. 1300
    “…Structurally, MERS-4 approached the RBD from the outside of the RBD-DPP4 binding interface. …”
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    Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
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