-
1281por Kim, Hye Rin, Jung, Younghun, Shin, Jonghyeok, Park, Myungseo, Kweon, Dae-Hyuk, Ban, Choongjin“…Peptide A2- or RBD-containing recombinant peptides linked to an enhanced green fluorescence protein (EGFP) were prepared by expression in Escherichia coli. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1282por Ao, Ling, Lu, Ting, Cao, Yu, Chen, Zhiwei, Wang, Yuting, Li, Zisheng, Ren, Xingqian, Xu, Pan, Peng, Mingli, Chen, Min, Zhang, Gaoli, Xiang, Dejuan, Cai, Dachuan, Hu, Peng, Shi, Xiaofeng, Zhang, Dazhi, Ren, Hong“…The safety, anti-receptor binding domain IgG (anti-RBD-IgG) and anti-spike-IgG responses, and RBD-specific memory B cell (MBC) responses were evaluated. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1283“…No significant correlation was observed between the levels of anti-RBD IgG and sex or age of the vaccinated individuals. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1284“…This study aims to discover novel peptide inhibitors against SARS-CoV-2 entry using computational approaches. The RBD binding domain of ACE2 was extracted and docked against the RBD. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1285por Nazarian, Shahram, Olad, Gholamreza, Abdolhamidi, Raziyeh, Motamedi, Mohammad Javad, Kazemi, Rouhollah, Kordbacheh, Emad, Felagari, Alireza, Olad, Hanieh, Ahmadi, Ali, Bahiraee, Alireza, Farahani, Parisa, Haghighi, Leila, Hassani, Faezeh, Hajhassan, Vahideh, Nadi, Mona, Sheikhi, Abdolkarim, Salimian, Jafar, Amani, Jafar“…METHODS: SARS-CoV-2 recombinant protein antigens, including truncated spike protein (SS1, lacking the N-terminal domain of S1), receptor-binding domain (RBD), and nucleoprotein (N) were used. Immunization program was performed via injection of RBD, SS1 +RBD, and SS1 +N along with different adjuvants, Alum, AS03, and Montanide at doses of 0, 40, 80, and 120 μg at three-time points in mice, rabbits, and primates. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1286por Maas, Dominique P. M. S. M., Saes, Joline L., Blijlevens, Nicole M. A., Cnossen, Marjon H., den Exter, Paul L., Kruis, Ilmar C., Meijer, Karina, Nieuwenhuizen, Laurens, Peters, Marjolein, Schutgens, Roger E. G., van Heerde, Waander L., Schols, Saskia E. M.“…OBJECTIVE: To describe general treatment plans of RBD patients and evaluate the use of peri‐procedural hemostatic therapy. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1287por Bate, Neil, Savva, Christos G., Moody, Peter C. E., Brown, Edward A., Evans, Sian E., Ball, Jonathan K., Schwabe, John W. R., Sale, Julian E., Brindle, Nicholas P. J.“…Here we use in vitro evolution to seek mutations in SARS-CoV-2 receptor binding domain (RBD) that would substantially increase binding to ACE2. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1288“…Prevalence of EDS, RBD, and RLS in PD patients was higher compared to that reported in studies during the pre-COVID-19 times. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1289por Röthenbacher, Annika, Cesari, Matteo, Doppler, Christopher E. J., Okkels, Niels, Willemsen, Nele, Sembowski, Nora, Seger, Aline, Lindner, Marie, Brune, Corinna, Stefani, Ambra, Högl, Birgit, Bialonski, Stephan, Borghammer, Per, Fink, Gereon R., Schober, Martin, Sommerauer, Michael“…Subsequently, 174 subjects (72 without RBD and 102 with RBD) were analysed with RBDtector to show the algorithm’s applicability. …”
Publicado 2022
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1290Structural basis for a conserved neutralization epitope on the receptor-binding domain of SARS-CoV-2por Huang, Kuan-Ying A., Chen, Xiaorui, Mohapatra, Arpita, Nguyen, Hong Thuy Vy, Schimanski, Lisa, Tan, Tiong Kit, Rijal, Pramila, Vester, Susan K., Hills, Rory A., Howarth, Mark, Keeffe, Jennifer R., Cohen, Alexander A., Kakutani, Leesa M., Wu, Yi-Min, Shahed-Al-Mahmud, Md, Chou, Yu-Chi, Bjorkman, Pamela J., Townsend, Alain R., Ma, Che“…We isolated a panel of neutralizing anti-receptor-binding domain (RBD) antibodies elicited upon natural infection and vaccination and showed that they recognize an immunogenic patch on the internal surface of the core RBD, which faces inwards and is hidden in the “down” state. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1291por Lu, Ruei-Min, Liang, Kang-Hao, Chiang, Hsiao-Ling, Hsu, Fu-Fei, Lin, Hsiu-Ting, Chen, Wan-Yu, Ke, Feng-Yi, Kumari, Monika, Chou, Yu-Chi, Tao, Mi-Hua, Yi-Ling Lin, Wu, Han-Chung“…Notably, the epitopes of these five K-RBD-mAbs are overlapping and localized around Y453 and F486 of the spike protein receptor binding domain (RBD). …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1292“…Isolated rapid eye movement sleep behavior disorder (iRBD) is a sleep disorder characterized by dream enactment behavior without any neurological disease and is frequently accompanied by cognitive dysfunction. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1293por Rahman, Md Shafiqur, Han, Min Jung, Kim, Sang Won, Kang, Seong Mu, Kim, Bo Ri, Kim, Heesun, Lee, Chang Jun, Noh, Jung Eun, Kim, Hanseong, Lee, Jie-Oh, Jang, Sung Key“…One aptamer interferes with the binding of ACE2 by blocking the ACE2-binding site in RBD, and the other aptamer allosterically inhibits ACE2 by binding to a distinct face of RBD. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1294“…The RNA-binding domain (RBD) of hnRNP U was previously mapped to an RGG/RG element within its disordered C-terminal region, but little is understood about its binding mode and potential for selective RNA recognition. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1295por Alushaj, Erind, Hemachandra, Dimuthu, Kuurstra, Alan, Menon, Ravi S., Ganjavi, Hooman, Sharma, Manas, Kashgari, Alia, Barr, Jennifer, Reisman, William, Khan, Ali R., MacDonald, Penny A.“…Alterations in brain iron suggest neurodegeneration; however, the literature on striatal iron has been inconsistent in PD and scant in RBD. Toward clarifying pathophysiological changes in PD and RBD, and uncovering possible biomarkers, we imaged 26 early-stage PD patients, 16 RBD patients, and 39 age-matched healthy controls with 3 T MRI. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1296por Wang, Tiantian, Zheng, Jing, Xu, Huifang, Wang, Zhongyi, Sun, Peng, Hou, Xuchen, Gong, Xin, Zhang, Bin, Wu, Jun, Liu, Bo“…To improve the broad-spectrum antiviral activity of the candidate vaccine, Delta RBD proteins were mixed with BA.2 RBD proteins at a ratio of 1:1 and then combined with two adjuvants—Al(OH)(3) and CpG—to prepare a bivalent vaccine. …”
Publicado 2023
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1297por Yu, Xiaojuan, Zhang, Senyan, Jiang, Liwei, Cui, Ye, Li, Dongxia, Wang, Dongli, Wang, Nianshuang, Fu, Lili, Shi, Xuanlin, Li, Ziqiang, Zhang, Linqi, Wang, Xinquan“…The MERS-27 epitope in the RBD overlaps with the binding site of the MERS-CoV receptor DPP4. …”
Publicado 2015
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1298por Chen, Guifang, Ma, Li-Chung, Wang, Shanshan, Woltz, Ryan L, Grasso, Emily M, Montelione, Gaetano T, Krug, Robert M“…We show that the N-terminal 152 amino-acid residue segment of DHX30, denoted DHX30N, possesses all the antiviral activity of DHX30 and contains a dsRNA-binding domain, and that the NS1-DHX30 interaction in vivo requires the dsRNA-binding activity of both DHX30N and the NS1 RBD. We demonstrate why this is the case using bacteria-expressed proteins: the DHX30N-NS1 RBD interaction in vitro requires the presence of a dsRNA platform that binds both NS1 RBD and DHX30N. …”
Publicado 2020
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1299por Pak, John E., Sharon, Chetna, Satkunarajah, Malathy, Auperin, Thierry C., Cameron, Cheryl M., Kelvin, David J., Seetharaman, Jayaraman, Cochrane, Alan, Plummer, Francis A., Berry, Jody D., Rini, James M.“…Both S and the RBD are highly immunogenic and both have been found to elicit neutralizing antibodies. …”
Publicado 2009
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto -
1300por Zhang, Senyan, Zhou, Panpan, Wang, Pengfei, Li, Yangyang, Jiang, Liwei, Jia, Wenxu, Wang, Han, Fan, Angela, Wang, Dongli, Shi, Xuanling, Fang, Xianyang, Hammel, Michal, Wang, Shuying, Wang, Xinquan, Zhang, Linqi“…Structurally, MERS-4 approached the RBD from the outside of the RBD-DPP4 binding interface. …”
Publicado 2018
Enlace del recurso
Enlace del recurso
Enlace del recurso
Online Artículo Texto