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1441por Hübner, M., Sauer, J., Ruhl, L., Kühne, J., Beushausen, K., Keil, J., Schael, M., Ius, F., Welte, T., Haverich, A., Gottlieb, J., Greer, M., Falk, C.“…Interestingly, S2-specific IgG MFI values were significantly elevated compared to RBD-specific IgG MFI values, both pre (S2 vs. RBD p<0.0001) and post LTx (S2 vs. …”
Publicado 2023
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1442por Ling, Tsai-Chieh, Chen, Po-Lin, Li, Nan-Yao, Ko, Wen-Chien, Sun, Chien-Yao, Chao, Jo-Yen, Shieh, Chi-Chang, Shen, Ching-Fen, Wu, Jia-Ling, Huang, Teng-Ching, Chao, Chiao-Hsuan, Wang, Jen-Ren, Chang, Yu-Tzu“…Although two doses of the AZD1222 vaccine initially elicited high anti-RBD antibody titers and neutralization against the ancestral virus and delta variant in hemodialysis patients, neutralizing antibodies against omicron variant were rarely detected, and the anti-RBD and neutralization antibodies waned over time. …”
Publicado 2023
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1443por Zhao, Guangyu, He, Lei, Sun, Shihui, Qiu, Hongjie, Tai, Wanbo, Chen, Jiawei, Li, Jiangfan, Chen, Yuehong, Guo, Yan, Wang, Yufei, Shang, Jian, Ji, Kaiyuan, Fan, Ruiwen, Du, Enqi, Jiang, Shibo, Li, Fang, Du, Lanying, Zhou, Yusen“…Both Nbs can be expressed in yeasts with high yield, bind to MERS-CoV RBD with high affinity, and block the binding of MERS-CoV RBD to the MERS-CoV receptor. …”
Publicado 2018
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1444por Patiño-Galindo, Juan Ángel, Filip, Ioan, Chowdhury, Ratul, Maranas, Costas D., Sorger, Peter K., AlQuraishi, Mohammed, Rabadan, Raul“…METHODS: By means of phylogenetic and recombination analyses, we found evidence of a recombination event in the RBD involving ancestral linages to both SARS-CoV and SARS-CoV-2. …”
Publicado 2021
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1445“…Median (interquartile range (IQR)) anti-RBD titres 1.5 months after vaccination were 9356 (5844–16 876) AU/mL; 3 months after vaccination, median anti-RBD titres had declined to 3952 (2190–8561) AU/mL (p < 0.001). …”
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1446por Blain, Hubert, Tuaillon, Edouard, Gamon, Lucie, Pisoni, Amandine, Miot, Stéphanie, Picot, Marie-Christine“…RBD-IgG levels of ≥592 BAU/mL were considered as high antibody response. …”
Publicado 2022
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1447por Montez-Rath, Maria E., Garcia, Pablo, Han, Jialin, Cadden, LinaCel, Hunsader, Patti, Morgan, Curt, Kerschmann, Russell, Beyer, Paul, Dittrich, Mary, Block, Geoffrey A, Anand, Shuchi, Parsonnet, Julie, Chertow, Glenn M“…Relative risks for infection were higher among patients with RBD index values < 23 (506 BAU/mL), compared with RBD index value ≥ 23 (RR 2.4 [95%CI 1.9, 3.0]). …”
Publicado 2022
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1448por Nam, Minjeong, Yun, Seung Gyu, Kim, Sang-wook, Kim, Chris Gunwoo, Cha, Jae Hyun, Lee, Cheonghwa, Kang, Seunghyuk, Park, Seul Gi, Kim, Sun Bean, Lee, Ki-Byung, Chung, You-Seung, Nam, Myung-Hyun, Lee, Chang Kyu, Cho, Yunjung“…The RBD Ab, NAb, and IGR levels were higher in females than in males at T(1) and T(2). …”
Publicado 2022
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1449por Deng, Shaofeng, Liu, Ying, Tam, Rachel Chun-Yee, Chen, Pin, Zhang, Anna Jinxia, Mok, Bobo Wing-Yee, Long, Teng, Kukic, Anja, Zhou, Runhong, Xu, Haoran, Song, Wenjun, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Zhiwei, Yuen, Kwok-Yung, Wang, Pui, Chen, Honglin“…We have developed an intranasal vaccine candidate based on a live attenuated influenza virus (LAIV) with a deleted NS1 gene that encodes cell surface expression of the receptor-binding-domain (RBD) of the SARS-CoV-2 spike protein, designated DelNS1-RBD4N-DAF. …”
Publicado 2023
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1450por Carli, Giulia, Meles, Sanne K., Janzen, Annette, Sittig, Elisabeth, Kogan, Rosalie V., Perani, Daniela, Oertel, Wolfgang H., Leenders, Klaus L.“…PURPOSE: Isolated REM sleep behaviour disorder (iRBD) patients are at high risk of developing clinical syndromes of the α-synuclein spectrum. …”
Publicado 2023
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1451por Limoges, Marc-André, Quenum, Akouavi Julite Irmine, Chowdhury, Mohammad Mobarak Hussain, Rexhepi, Fjolla, Namvarpour, Mozhdeh, Akbari, Sara Ali, Rioux-Perreault, Christine, Nandi, Madhuparna, Lucier, Jean-François, Lemaire-Paquette, Samuel, Premkumar, Lakshmanane, Durocher, Yves, Cantin, André, Lévesque, Simon, Dionne, Isabelle J., Menendez, Alfredo, Ilangumaran, Subburaj, Allard-Chamard, Hugues, Piché, Alain, Ramanathan, Sheela“…SARS-CoV-2 D614G and omicron RBD specific B cell subsets in peripheral circulation were assessed by flow cytometry. …”
Publicado 2023
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1452por Tan, Tiong Kit, Rijal, Pramila, Rahikainen, Rolle, Keeble, Anthony H., Schimanski, Lisa, Hussain, Saira, Harvey, Ruth, Hayes, Jack W. P., Edwards, Jane C., McLean, Rebecca K., Martini, Veronica, Pedrera, Miriam, Thakur, Nazia, Conceicao, Carina, Dietrich, Isabelle, Shelton, Holly, Ludi, Anna, Wilsden, Ginette, Browning, Clare, Zagrajek, Adrian K., Bialy, Dagmara, Bhat, Sushant, Stevenson-Leggett, Phoebe, Hollinghurst, Philippa, Tully, Matthew, Moffat, Katy, Chiu, Chris, Waters, Ryan, Gray, Ashley, Azhar, Mehreen, Mioulet, Valerie, Newman, Joseph, Asfor, Amin S., Burman, Alison, Crossley, Sylvia, Hammond, John A., Tchilian, Elma, Charleston, Bryan, Bailey, Dalan, Tuthill, Tobias J., Graham, Simon P., Duyvesteyn, Helen M. E., Malinauskas, Tomas, Huo, Jiandong, Tree, Julia A., Buttigieg, Karen R., Owens, Raymond J., Carroll, Miles W., Daniels, Rodney S., McCauley, John W., Stuart, David I., Huang, Kuan-Ying A., Howarth, Mark, Townsend, Alain R.“…Using competition assays with a monoclonal antibody panel, we show that RBD-SpyVLP induces a polyclonal antibody response that recognises key epitopes on the RBD, reducing the likelihood of selecting neutralisation-escape mutants. …”
Publicado 2021
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1453por Iyer, Anita S., Jones, Forrest K., Nodoushani, Ariana, Kelly, Meagan, Becker, Margaret, Slater, Damien, Mills, Rachel, Teng, Erica, Kamruzzaman, Mohammad, Garcia-Beltran, Wilfredo F., Astudillo, Michael, Yang, Diane, Miller, Tyler E., Oliver, Elizabeth, Fischinger, Stephanie, Atyeo, Caroline, Iafrate, A. John, Calderwood, Stephen B., Lauer, Stephen A., Yu, Jingyou, Li, Zhenfeng, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Branda, John A., Turbett, Sarah E., LaRocque, Regina C., Mellon, Guillaume, Barouch, Dan H., Schmidt, Aaron G., Azman, Andrew S., Alter, Galit, Ryan, Edward T, Harris, Jason B., Charles, Richelle C.“…In contrast, anti-RBD IgG responses decayed slowly through 90 days with only 3 seropositive individuals seroreverting within this time period. …”
Publicado 2020
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1454por Du, Yaoqiang, Wang, Hao, Chen, Linjie, Fang, Quan, Zhang, Biqin, Jiang, Luxi, Wu, Zhaoyu, Yang, Yexiaoqing, Zhou, Ying, Chen, Bingyu, Lyu, Jianxin, Wang, Zhen“…The receptor-binding motif (RBM, 438–506) is a region that directly interacts with ACE2 receptor in the RBD and plays a crucial role in determining affinity. …”
Publicado 2021
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1455“…BACKGROUND: The objective was to investigate the individual effect and potential interactions of probable rapid eye movement sleep behavior disorder (pRBD) and sleep insufficiency on fall risk among a Chinese elderly population. …”
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1456por Morinaga, Yoshitomo, Tani, Hideki, Terasaki, Yasushi, Nomura, Satoshi, Kawasuji, Hitoshi, Shimada, Takahisa, Igarashi, Emiko, Saga, Yumiko, Yoshida, Yoshihiro, Yasukochi, Rei, Kaneda, Makito, Murai, Yushi, Ueno, Akitoshi, Miyajima, Yuki, Fukui, Yasutaka, Nagaoka, Kentaro, Ono, Chikako, Matsuura, Yoshiharu, Fujimura, Takashi, Ishida, Yoichi, Oishi, Kazunori, Yamamoto, Yoshihiro“…The CRNT and commercial anti-RBD antibody test effectively classified convalescent COVID-19 patients. …”
Publicado 2021
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1457por Joyce, M G, Chen, Wei-Hung, Sankhala, Rajeshwer, Hajduczki, Agnes, Thomas, Paul, Martinez, Elizabeth, Peterson, Caroline, Rao, Mangala, Modjarrad, Kayvon“…In order to understand the breadth of vaccine-elicited antibody responses, we analyzed SpFN- and RBD-FN-immunized animal sera against a set of heterologous SARS-CoV-2 RBD variants and SARS-CoV RBD. …”
Publicado 2021
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1458por Fujigaki, Hidetsugu, Yamamoto, Yasuko, Koseki, Takenao, Banno, Sumi, Ando, Tatsuya, Ito, Hiroyasu, Fujita, Takashi, Naruse, Hiroyuki, Hata, Tadayoshi, Moriyama, Saya, Takahashi, Yoshimasa, Suzuki, Tadaki, Murakami, Takahiro, Yoshida, Yukihiro, Yagura, Yo, Oyamada, Takayoshi, Takemura, Masao, Kondo, Masashi, Iwata, Mitsunaga, Saito, Kuniaki“…A chemiluminescent enzyme immunoassay (CLEIA) method to measure IgG against RBD was developed and validated for the clinical setting. …”
Publicado 2022
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1459por Traoré, Abdouramane, Guindo, Merepen A., Konaté, Drissa, Traoré, Bourama, Diakité, Seidina A., Kanté, Salimata, Dembélé, Assitan, Cissé, Abdourhamane, Incandela, Nathan C., Kodio, Mamoudou, Coulibaly, Yaya I., Faye, Ousmane, Kajava, Andrey V., Pratesi, Federico, Migliorini, Paola, Papini, Anna Maria, Pacini, Lorenzo, Rovero, Paolo, Errante, Fosca, Diakité, Mahamadou, Arevalo-Herrera, Myriam, Herrera, Socrates, Corradin, Giampietro, Balam, Saidou“…Higher antibody levels to S, RBD, and RBM at hospital entry were associated with shorter treatment durations, particularly for RBD (p < 0.01). …”
Publicado 2022
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1460por He, Cai, Yang, Jingyun, Hong, Weiqi, Chen, Zimin, Peng, Dandan, Lei, Hong, Alu, Aqu, He, Xuemei, Bi, Zhenfei, Jiang, Xiaohua, Jia, Guowen, Yang, Yun, Zhou, Yanan, Yu, Wenhai, Tang, Cong, Huang, Qing, Yang, Mengli, Li, Bai, Li, Jingmei, Wang, Junbin, Que, Haiying, Chen, Li, Ren, Wenyan, Wan, Dandan, Li, Jiong, Wang, Wei, Shen, Guobo, Zhao, Zhiwei, Yang, Li, Yang, Jinliang, Wang, Zhenling, Su, Zhaoming, Wei, Yuquan, Cen, Xiaobo, Tanaka, Yoshimasa, Song, Xiangrong, Lu, Shuaiyao, Peng, Xiaozhong, Lu, Guangwen, Wei, Xiawei“…Here, we developed a subunit vaccine named RBD-HR/trimer by directly linking the sequence of RBD derived from the Delta variant (containing L452R and T478K) and HR1 and HR2 in SARS-CoV-2 S2 subunit in a tandem manner, which can self-assemble into a trimer. …”
Publicado 2022
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