Mostrando 161 - 180 Resultados de 5,191 Para Buscar '"RBD"', tiempo de consulta: 0.34s Limitar resultados
  1. 161
    “…Neutralizing activity of NTD mAbs but not RBD mAbs against a clinical viral isolate carrying E484K as well as extensive changes in the NTD was abolished, suggesting that a proportion of vaccine-induced RBD binding antibodies may provide substantial protection against viral variants carrying single E484K RBD mutations.…”
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    SARS-CoV-2 mRNA vaccination induces functionally diverse antibodies to NTD, RBD, and S2
  2. 162
    “…The SARS-CoV-2 S RBD is a major target of neutralizing antibodies (NAbs) that block RBD - ACE2 interactions. …”
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    Epitope Classification and RBD Binding Properties of Neutralizing Antibodies Against SARS-CoV-2 Variants of Concern
  3. 163
    “…These data show that “public” NTD-directed and other non-RBD plasma antibodies are prevalent and have implications for SARS-CoV-2 protection and antibody escape.…”
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    Prevalent, protective, and convergent IgG recognition of SARS-CoV-2 non-RBD spike epitopes
  4. 164
    “…In this study, we evaluated the immunogenicity of a receptor-binding domain (RBD) of SARS-CoV-2 spike glycoprotein loaded into N,N,N-trimethyl chitosan nanoparticles (RBD-TMC NPs). …”
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    Intranasal Administration of RBD Nanoparticles Confers Induction of Mucosal and Systemic Immunity against SARS-CoV-2
  5. 165
    “…It is known that the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2 interacts with the human angiotensin-converting enzyme 2 (ACE2) receptor, initiating the entry of SARS-CoV-2. …”
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    Differential Interactions Between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern
  6. 166
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    Identification of Potential Binding Sites of Sialic Acids on the RBD Domain of SARS-CoV-2 Spike Protein
  7. 167
    “…We found that the anti-Spike antibodies do not recognize PF4, on the contrary, the anti-PF4 antibodies show some cross-reactivity for Spike-RBD. More interestingly, we report for the first time that the PF4 and Spike-RBD proteins can bind each other. …”
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    Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis
  8. 168
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    Structure-based analyses of neutralization antibodies interacting with naturally occurring SARS-CoV-2 RBD variants
  9. 169
    “…Here, a novel SARS-CoV-2 receptor-binding domain (RBD) homodimer was developed as a SARS-CoV-2 vaccine candidate. …”
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    RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates
  10. 170
    “…Here, we describe a protocol to identify escape mutants on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) receptor-binding domain (RBD) using a yeast screen combined with deep mutational scanning. …”
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    Identification of SARS-CoV-2 S RBD escape mutants using yeast screening and deep mutational scanning
  11. 171
    “…In this study, we used a semi-stable mammalian episomal expression system to produce high quantities of the receptor-binding domain-RBD of SARS-CoV-2 in a simple and very economical way. …”
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    Development and evaluation of a low cost IgG ELISA test based in RBD protein for COVID-19
  12. 172
    “…The angiotensin-converting enzyme 2 (ACE2) is the receptor used by SARS-CoV and SARS-CoV-2 coronaviruses to attach to cells via the receptor-binding domain (RBD) of their viral spike protein. Since the start of the COVID-19 pandemic, several structures of protein complexes involving ACE2 and RBD as well as monoclonal antibodies and nanobodies have become available. …”
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    A Collection of Designed Peptides to Target SARS-CoV-2 Spike RBD—ACE2 Interaction
  13. 173
    “…SARS-CoV-2 receptor-binding domain (RBD) plays fundamental roles related to cell infection. …”
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    Structure-Based Epitope Design: Toward a Greater Antibody–SARS-CoV-2 RBD Affinity
  14. 174
    “…Recently, we have developed a lipid nanoparticle-encapsulated mRNA (mRNA-LNP) encoding the receptor-binding domain (RBD) of SARS-CoV-2 (termed ARCoV), which confers complete protection in mouse model. …”
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    Long-term stability and protection efficacy of the RBD-targeting COVID-19 mRNA vaccine in nonhuman primates
  15. 175
    por Ferenci, Tamás, Sarkadi, Balázs
    Publicado 2022
    “…BACKGROUND: Limited information is available on the effectiveness of the BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine, especially in the elderly, despite the fact that it is approved in more than 50 countries. METHODS: RBD-specific antibody titres, as a rapidly available and highly predictive surrogate marker, were measured after two doses of the BBIBP-CorV vaccine in 450 subjects. …”
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    RBD-specific antibody responses after two doses of BBIBP-CorV (Sinopharm, Beijing CNBG) vaccine
  16. 176
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    Differential interactions between human ACE2 and spike RBD of SARS-CoV-2 variants of concern
  17. 177
    “…The epitope of 2G1 on RBD partially overlaps with angiotensin converting enzyme 2 (ACE2) interface, which enables 2G1 to block interaction between RBD and ACE2. …”
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    Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
  18. 178
    “…RESULTS: We found that in seven of the 12 variants studied, there was a structural alteration in the RBD region, further affecting its stability and function. …”
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    Impact of B.1.617 and RBD SARS-CoV-2 variants on vaccine efficacy: An in-silico approach
  19. 179
    “…The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) variants, particularly those with multiple mutations in receptor‐binding domain (RBD), pose a critical challenge to the efficacy of coronavirus disease 2019 (COVID‐19) vaccines and therapeutic neutralizing monoclonal antibodies (mAbs). …”
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    Antigenicity comparison of SARS‐CoV‐2 Omicron sublineages with other variants contained multiple mutations in RBD
  20. 180
    “…Previously, we developed the protein subunit vaccine ZF2001 based on the dimeric receptor-binding domain (RBD) of prototype SARS-CoV-2. Here, we developed a chimeric RBD-dimer vaccine approach to adapt SARS-CoV-2 variants. …”
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    Protective prototype-Beta and Delta-Omicron chimeric RBD-dimer vaccines against SARS-CoV-2
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