Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies

por Mercurio, Ivan, Tragni, Vincenzo, Busto, Francesco, De Grassi, Anna, Pierri, Ciro Leonardo
Publicado 2020

Convergent Antibody Responses to SARS-CoV-2 in Convalescent Individuals

por Robbiani, Davide F., Gaebler, Christian, Muecksch, Frauke, Lorenzi, Julio C. C., Wang, Zijun, Cho, Alice, Agudelo, Marianna, Barnes, Christopher O., Gazumyan, Anna, Finkin, Shlomo, Hägglöf, Thomas, Oliveira, Thiago Y., Viant, Charlotte, Hurley, Arlene, Hoffmann, Hans-Heinrich, Millard, Katrina G., Kost, Rhonda G., Cipolla, Melissa, Gordon, Kristie, Bianchini, Filippo, Chen, Spencer T., Ramos, Victor, Patel, Roshni, Dizon, Juan, Shimeliovich, Irina, Mendoza, Pilar, Hartweger, Harald, Nogueira, Lilian, Pack, Maggi, Horowitz, Jill, Schmidt, Fabian, Weisblum, Yiska, Michailidis, Eleftherios, Ashbrook, Alison W., Waltari, Eric, Pak, John E., Huey-Tubman, Kathryn E., Koranda, Nicholas, Hoffman, Pauline R., West, Anthony P., Rice, Charles M., Hatziioannou, Theodora, Bjorkman, Pamela J., Bieniasz, Paul D., Caskey, Marina, Nussenzweig, Michel C.
Publicado 2020

Associated factors of REM sleep without atonia in younger (≤ 50 years) hospitalized psychiatric patients

por Bušková, Jitka, Miletínová, Eva, Kliková, Monika, Bareš, Martin, Novák, Tomáš, Kosová, Jiřina, Stopková, Pavla, Kopřivová, Jana
Publicado 2020

Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity

por Ripperger, Tyler J., Uhrlaub, Jennifer L., Watanabe, Makiko, Wong, Rachel, Castaneda, Yvonne, Pizzato, Hannah A., Thompson, Mallory R., Bradshaw, Christine, Weinkauf, Craig C., Bime, Christian, Erickson, Heidi L., Knox, Kenneth, Bixby, Billie, Parthasarathy, Sairam, Chaudhary, Sachin, Natt, Bhupinder, Cristan, Elaine, El Aini, Tammer, Rischard, Franz, Campion, Janet, Chopra, Madhav, Insel, Michael, Sam, Afshin, Knepler, James L., Capaldi, Andrew P., Spier, Catherine M., Dake, Michael D., Edwards, Taylor, Kaplan, Matthew E., Scott, Serena Jain, Hypes, Cameron, Mosier, Jarrod, Harris, David T., LaFleur, Bonnie J., Sprissler, Ryan, Nikolich-Žugich, Janko, Bhattacharya, Deepta
Publicado 2020

Engineered ACE2 receptor traps potently neutralize SARS-CoV-2

por Glasgow, Anum, Glasgow, Jeff, Limonta, Daniel, Solomon, Paige, Lui, Irene, Zhang, Yang, Nix, Matthew A., Rettko, Nicholas J., Zha, Shoshana, Yamin, Rachel, Kao, Kevin, Rosenberg, Oren S., Ravetch, Jeffrey V., Wiita, Arun P., Leung, Kevin K., Lim, Shion A., Zhou, Xin X., Hobman, Tom C., Kortemme, Tanja, Wells, James A.
Publicado 2020

Cryo-EM Structures of SARS-CoV-2 Spike without and with ACE2 Reveal a pH-Dependent Switch to Mediate Endosomal Positioning of Receptor-Binding Domains

por Zhou, Tongqing, Tsybovsky, Yaroslav, Gorman, Jason, Rapp, Micah, Cerutti, Gabriele, Chuang, Gwo-Yu, Katsamba, Phinikoula S., Sampson, Jared M., Schön, Arne, Bimela, Jude, Boyington, Jeffrey C., Nazzari, Alexandra, Olia, Adam S., Shi, Wei, Sastry, Mallika, Stephens, Tyler, Stuckey, Jonathan, Teng, I-Ting, Wang, Pengfei, Wang, Shuishu, Zhang, Baoshan, Friesner, Richard A., Ho, David D., Mascola, John R., Shapiro, Lawrence, Kwong, Peter D.
Publicado 2020

Cross-species recognition of SARS-CoV-2 to bat ACE2

por Liu, Kefang, Tan, Shuguang, Niu, Sheng, Wang, Jia, Wu, Lili, Sun, Huan, Zhang, Yanfang, Pan, Xiaoqian, Qu, Xiao, Du, Pei, Meng, Yumin, Jia, Yunfei, Chen, Qian, Deng, Chuxia, Yan, Jinghua, Wang, Hong-Wei, Wang, Qihui, Qi, Jianxun, Gao, George Fu
Publicado 2021

Engineered SARS-CoV-2 receptor binding domain improves immunogenicity in mice and elicits protective immunity in hamsters

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan, Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021

Structural Basis of Neutralization by a Human Anti-severe Acute Respiratory Syndrome Spike Protein Antibody, 80R

por Hwang, William C., Lin, Yaqiong, Santelli, Eugenio, Sui, Jianhua, Jaroszewski, Lukasz, Stec, Boguslaw, Farzan, Michael, Marasco, Wayne A., Liddington, Robert C.
Publicado 2006

Binding and molecular basis of the bat coronavirus RaTG13 virus to ACE2 in humans and other species

por Liu, Kefang, Pan, Xiaoqian, Li, Linjie, Yu, Feng, Zheng, Anqi, Du, Pei, Han, Pengcheng, Meng, Yumin, Zhang, Yanfang, Wu, Lili, Chen, Qian, Song, Chunli, Jia, Yunfei, Niu, Sheng, Lu, Dan, Qiao, Chengpeng, Chen, Zhihai, Ma, Dongli, Ma, Xiaopeng, Tan, Shuguang, Zhao, Xin, Qi, Jianxun, Gao, George F., Wang, Qihui
Publicado 2021

Anti-SARS-CoV-2 Receptor-Binding Domain Total Antibodies Response in Seropositive and Seronegative Healthcare Workers Undergoing COVID-19 mRNA BNT162b2 Vaccination

por Salvagno, Gian Luca, Henry, Brandon M., di Piazza, Giovanni, Pighi, Laura, De Nitto, Simone, Bragantini, Damiano, Gianfilippi, Gian Luca, Lippi, Giuseppe
Publicado 2021

Immune response to SARS-CoV-2 variants of concern in vaccinated individuals

por Becker, Matthias, Dulovic, Alex, Junker, Daniel, Ruetalo, Natalia, Kaiser, Philipp D., Pinilla, Yudi T., Heinzel, Constanze, Haering, Julia, Traenkle, Bjoern, Wagner, Teresa R., Layer, Mirjam, Mehrlaender, Martin, Mirakaj, Valbona, Held, Jana, Planatscher, Hannes, Schenke-Layland, Katja, Krause, Gérard, Strengert, Monika, Bakchoul, Tamam, Althaus, Karina, Fendel, Rolf, Kreidenweiss, Andrea, Koeppen, Michael, Rothbauer, Ulrich, Schindler, Michael, Schneiderhan-Marra, Nicole
Publicado 2021

In silico binding profile characterization of SARS-CoV-2 spike protein and its mutants bound to human ACE2 receptor

por Zhang, Yuzhao, He, Xibing, Zhai, Jingchen, Ji, Beihong, Man, Viet Hoang, Wang, Junmei
Publicado 2021

Antibody Responses and the Effects of Clinical Drugs in COVID-19 Patients

por Wei, Liwen, Shang, Yuqi, Liu, Xi, Li, Xinghua, Chen, Gongqi, Liang, Siping, Zou, Zhengyu, Ding, Tao, Hong, Zhongsi, Wu, Minhao, Xia, Jinyu
Publicado 2021

CD209L/L-SIGN and CD209/DC-SIGN Act as Receptors for SARS-CoV-2

por Amraei, Razie, Yin, Wenqing, Napoleon, Marc A., Suder, Ellen L., Berrigan, Jacob, Zhao, Qing, Olejnik, Judith, Chandler, Kevin Brown, Xia, Chaoshuang, Feldman, Jared, Hauser, Blake M., Caradonna, Timothy M., Schmidt, Aaron G., Gummuluru, Suryaram, Mühlberger, Elke, Chitalia, Vipul, Costello, Catherine E., Rahimi, Nader
Publicado 2021

A Vaccine Based on the Receptor-Binding Domain of the Spike Protein Expressed in Glycoengineered Pichia pastoris Targeting SARS-CoV-2 Stimulates Neutralizing and Protective Antibod...

por Liu, Bo, Yin, Ying, Liu, Yuxiao, Wang, Tiantian, Sun, Peng, Ou, Yangqin, Gong, Xin, Hou, Xuchen, Zhang, Jun, Ren, Hongguang, Luo, Shiqiang, Ke, Qian, Yao, Yongming, Xu, Junjie, Wu, Jun
Publicado 2022

Review of the mechanisms of SARS-CoV-2 evolution and transmission

por Chen, Jiahui, Wang, Rui, Wei, Guo-Wei
Publicado 2021

Engineered SARS-CoV-2 receptor binding domain improves manufacturability in yeast and immunogenicity in mice

por Dalvie, Neil C., Rodriguez-Aponte, Sergio A., Hartwell, Brittany L., Tostanoski, Lisa H., Biedermann, Andrew M., Crowell, Laura E., Kaur, Kawaljit, Kumru, Ozan S., Carter, Lauren, Yu, Jingyou, Chang, Aiquan, McMahan, Katherine, Courant, Thomas, Lebas, Celia, Lemnios, Ashley A., Rodrigues, Kristen A., Silva, Murillo, Johnston, Ryan S., Naranjo, Christopher A., Tracey, Mary Kate, Brady, Joseph R., Whittaker, Charles A., Yun, Dongsoo, Brunette, Natalie, Wang, Jing Yang, Walkey, Carl, Fiala, Brooke, Kar, Swagata, Porto, Maciel, Lok, Megan, Andersen, Hanne, Lewis, Mark G., Love, Kerry R., Camp, Danielle L., Silverman, Judith Maxwell, Kleanthous, Harry, Joshi, Sangeeta B., Volkin, David B., Dubois, Patrice M., Collin, Nicolas, King, Neil P., Barouch, Dan H., Irvine, Darrell J., Love, J. Christopher
Publicado 2021

Effect of identified non-synonymous mutations in DPP4 receptor binding residues among highly exposed human population in Morocco to MERS-CoV through computational approach

por Abbad, Anass, Anga, Latifa, Faouzi, Abdellah, Iounes, Nadia, Nourlil, Jalal
Publicado 2021

Genetic and structural basis for SARS-CoV-2 variant neutralization by a two-antibody cocktail

por Dong, Jinhui, Zost, Seth J., Greaney, Allison J., Starr, Tyler N., Dingens, Adam S., Chen, Elaine C., Chen, Rita E., Case, James Brett, Sutton, Rachel E., Gilchuk, Pavlo, Rodriguez, Jessica, Armstrong, Erica, Gainza, Christopher, Nargi, Rachel S., Binshtein, Elad, Xie, Xuping, Zhang, Xianwen, Shi, Pei-Yong, Logue, James, Weston, Stuart, McGrath, Marisa E., Frieman, Matthew B., Brady, Tyler, Tuffy, Kevin, Bright, Helen, Loo, Yueh-Ming, McTamney, Patrick M., Esser, Mark T., Carnahan, Robert H., Diamond, Michael S., Bloom, Jesse D., Crowe, James E.
Publicado 2021