Mostrando 621 - 640 Resultados de 292,959 Para Buscar '"Receptor"', tiempo de consulta: 1.14s Limitar resultados
  1. 621
  2. 622
    por An, Ki-Chan
    Publicado 2016
    “…Selective estrogen receptor modulators (SERMs) are now being used as a treatment for breast cancer, osteoporosis and postmenopausal symptoms, as these drugs have features that can act as an estrogen agonist and an antagonist, depending on the target tissue. …”
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  3. 623
    “…PTGs and LTs exert their biological functions by binding to cognate receptors, which belong to the seven transmembrane, G protein-coupled receptor superfamily. …”
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  4. 624
    por Zhang, Xiao-Ying, Zhang, Pei-Ying
    Publicado 2016
    “…Receptor tyrosine kinases (RTKs) are cell surface glycoproteins with enzymatic activity involved in the regulation of various important functions. …”
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  5. 625
    “…Targeted inhibition of members of the TAM (TYRO-3, AXL, MERTK) family of receptor tyrosine kinases has recently been investigated as a novel strategy for treatment of hematologic malignancies. …”
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  6. 626
    “…Unexpectedly, DsecIr75a encodes a functional receptor, due to efficient translational readthrough of the PTC. …”
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  7. 627
    por Tuncel, Murat
    Publicado 2017
    “…Thyroid stimulating hormone receptor (TSHR) plays a pivotal role in thyroid hormone metabolism. …”
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  8. 628
  9. 629
  10. 630
    “…Chimeric antigen receptors (CARs) are recombinant protein molecules that redirect cytotoxic lymphocytes toward malignant and other target cells. …”
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  11. 631
    por Al-Sabah, Suleiman
    Publicado 2016
    “…These biological functions make their respective receptors (GIPR and GLP-1R) attractive targets in the treatment of both type 2 diabetes mellitus (T2DM) and obesity. …”
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  12. 632
    “…Examples of responses and adaptation include (de)activation, proliferation/apoptosis, and (de)differentiation. Receptor-mediated cell mechanosensing is a multistep process that is initiated by binding of cell surface receptors to their ligands on the extracellular matrix or the surface of adjacent cells. …”
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  13. 633
    “…Toll-like receptors (TLRs) are known as pattern-recognition receptors related to the Toll protein of Drosophila. …”
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  14. 634
    por Guo, Hao, Smith, Dean P
    Publicado 2017
    “…In flies, 60 “tuning” receptor subunits combine with a common subunit, Orco (odorant receptor coreceptor) to form ligand-gated ion channels. …”
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  15. 635
    “…This commentary highlights the recent work published in journal Nature on the structural based discovery of novel analgesic compounds for opioid receptors with minimal effects. Manglik et al. selectively targeted the Gi based μOR pathway instead of the β-arrestin pathway of the opioids. …”
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  16. 636
  17. 637
    por Wicher, Dieter
    Publicado 2018
    “…Among the insect olfactory receptors the odorant receptors (ORs) evolved in parallel to the onset of insect flight. …”
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  18. 638
    “…Biochemical and pharmacological studies have identified the structure of leukotrienes, the pathways that lead to their synthesis, and the signaling events they trigger when they interact with their cognate receptors. A privileged interaction exists between these lipid mediators and another group of molecules essential for inflammation and immune modulation, namely, cytokines. …”
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  19. 639
    por Matsuoka, Toshiyuki, Narumiya, Shuh
    Publicado 2007
    “…They are the PGD receptor (DP), four subtypes of the PGE receptor (EP(1), EP(2), EP(3), and EP(4)), the PGF receptor (FP), PGI receptor (IP), and TXA receptor (TP). …”
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  20. 640
    por Short, Ben
    Publicado 2018
    “…Researchers use single-particle electron microscopy to visualize an insulin-induced conformational shift that leads to receptor activation.…”
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