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721por Ge, Haojie, Ye, Ling, Cai, Yueyi, Guo, Huimin, Gu, Dan, Xu, Zhengzhong, Hu, Maozhi, Allison, Heather E., Jiao, Xin'an, Chen, Xiang“…Adsorption rate and transmission electron microscopy experiments showed that the receptor for phage LP31 was the O(9) antigen of S. …”
Publicado 2023
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722“…Their success, however, is often temporary and limited to a subset of patients whose tumors express estrogen receptor alpha (ER). The therapies are entirely ineffective in ER-negative disease. …”
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723“…At first, it was thought that ATP was simply involved in acute pain, since ATP is released from damaged cells and excites directly primary sensory neurons by activating their receptors. However, neither blocking P2X/Y receptors pharmacologically nor suppressing the expression of P2X/Y receptors molecularly in sensory neurons or in the spinal cord had an effect on acute physiological pain. …”
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724Publicado 1984“…Rat hepatocytes in monolayer culture rapidly internalized asialoglycoproteins and the receptors to which they are bound. Subsequent to endocytosis, the receptor-ligand complex is dissociated within an acidic endosome (Harford, J., K. …”
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725Publicado 1984“…The metabolism of the receptor for epidermal growth factor (EGF) has been measured by labeling the receptor in vivo with radioactive amino acid precursors and then determining, by immunoprecipitation with specific anti-EGF receptor antisera, the rate of degradation of the receptor when the cells are placed in a nonradioactive medium. …”
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726Publicado 1995“…The subcellular distribution of sarcolemmal dihydropyridine receptor (DHPR) and sarcoplasmic reticular triadin and Ca2+ release channel/ryanodine receptor (RyR) was determined in adult rabbit ventricle and atrium by double labeling immunofluorescence and laser scanning confocal microscopy. …”
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727Publicado 1995“…Both the internalization and degradation of 125I-TSP1 could be inhibited by a specific antagonist of the LDLR family, the 39-kD receptor-associated protein (RAP). Antibodies to the LDLR-related protein (LRP) completely blocked the uptake and degradation of 125I-TSP1 in SMCs and fibroblasts but not endothelial cells. …”
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728Publicado 1996“…The high-affinity NGF receptor is thought to be a complex of two receptors , gp75 and the tyrosine kinase TrkA, but direct biochemical evidence for such an association had been lacking. …”
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729“…Stimulation of G protein–coupled receptors (GPCR) transactivates the EGF receptors (EGFRs), which occurs via a metalloprotease-dependent cleavage of heparin-binding EGF (HB-EGF). …”
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730Publicado 1978“…Accordingly, isolated NP binding receptors from NP-sensitized B lymphocytes are largely devoid of this idiotype. …”
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731Publicado 1990“…IL-4, a pleiotropic cytokine produced by T lymphocytes, plays an important role in immune responsiveness by regulating proliferation and differentiation of a variety of lymphoid and myeloid cells via binding to high affinity receptors. In this report we describe the isolation and functional expression of a human IL-4-R cDNA. …”
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732Publicado 1986“…This receptor for glucose-modified proteins is now shown to be distinct from previously described scavenger receptors, using competition and crosscompetition experiments between AGE-modified protein and a variety of in vitro- modified scavenger receptor ligands, including unmodified BSA, unmodified low-density lipoproteins (LDL), acetyl-LDL, maleyl-BSA, and formaldehyde-treated BSA. …”
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733
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734“…Rats exposed to SPS showed enhanced inhibition of the hypothalamo-pituitary-adrenal (HPA) axis, which has been reliably reproduced in patients with PTSD. Mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) in the hippocampus regulate HPA axis by glucocorticoid negative feedback. …”
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736por N'Diaye, Elsa-Noah, Branda, Catherine S., Branda, Steven S., Nevarez, Lisette, Colonna, Marco, Lowell, Clifford, Hamerman, Jessica A., Seaman, William E.“…Phagocytosis, which is essential for the immune response to pathogens, is initiated by specific interactions between pathogens and cell surface receptors expressed by phagocytes. This study identifies triggering receptor expressed on myeloid cells 2 (TREM-2) and its signaling counterpart DAP12 as a molecular complex that promotes phagocytosis of bacteria. …”
Publicado 2009
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737“…BACKGROUND: Classically, progesterone has been thought to act only through the well-known genomic pathway involving hormone binding to nuclear receptors and subsequent modulation of gene expression. …”
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738por Scola, Anne-Marie, Johswich, Kay-Ole, Morgan, B. Paul, Klos, Andreas, Monk, Peter N.“…C5L2 is a 7 transmembrane domain receptor for complement fragment C5a that, unlike the classical C5a receptor, C5aR, does not couple to G proteins. …”
Publicado 2009
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739“…Nuclear receptor Rev-erbα (NR1D1), previously considered to be an orphan nuclear receptor, is a receptor for heme, which promotes transcriptional repression via recruitment of the NCoR-HDAC3 corepressor complex. …”
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740por Weller, Melodie L., Amornphimoltham, Panomwat, Schmidt, Michael, Wilson, Paul A., Gutkind, J. Silvio, Chiorini, John A.“…Subsequent experiments suggest EGFR is necessary for vector internalization and likely functions as a co-receptor for this virus.…”
Publicado 2010
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