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Mostrando 841 - 860 Resultados de 292,959 Para Buscar '"Receptor"', tiempo de consulta: 1.29s Limitar resultados
  1. 841
    “…Glucocorticoid (GC) actions are mediated through two closely related ligand-dependent transcription factors, the GC receptor (GR) and the mineralocorticoid receptor (MR). …”
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    Glucocorticoid-dependent transcription in skin requires epidermal expression of the glucocorticoid receptor and is modulated by the mineralocorticoid receptor
  2. 842
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    Synaptic receptors for low pH in extracellular space: metabotropic receptors are an underestimated factor in stroke
  3. 843
    “…Responses to these stresses directly involve plasma membrane receptor proteins known as receptor-like kinases and receptor-like proteins. …”
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    Orthology and synteny analysis of receptor-like kinases “RLK” and receptor-like proteins “RLP” in legumes
  4. 844
    “…G protein-coupled receptors (GPCRs) are versatile signaling proteins that mediate complex cellular responses to hormones and neurotransmitters. …”
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    Structural Insights into Ligand—Receptor Interactions Involved in Biased Agonism of G-Protein Coupled Receptors
  5. 845
    Materias: “…Steroid Hormones and Receptors…”
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    Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels
  6. 846
    “…Agonists of the G(i) protein-coupled A(3) adenosine receptor (A(3)AR) have shown important pain-relieving properties in preclinical settings of several pain models. …”
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    Uncovering the Mechanisms of Adenosine Receptor-Mediated Pain Control: Focus on the A(3) Receptor Subtype
  7. 847
    “…Protein-protein interactions between G protein-coupled receptors (GPCRs) can augment their functionality and increase the repertoire of signaling pathways they regulate. …”
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    Evidence for Protein–Protein Interaction between Dopamine Receptors and the G Protein-Coupled Receptor 143
  8. 848
    “…Farnesoid X receptor (FXR) is a bile acid receptor that regulates the inflammatory response. …”
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    Pathophysiology of reflux oesophagitis: role of Toll-like receptors 2 and 4 and Farnesoid X receptor
  9. 849
    “…BACKGROUND: The existence of oestrogen receptor-negative (ER−)/progesterone receptor-positive (PR+) breast cancer continues to be an area of controversy amongst oncologists and pathologists. …”
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    Is oestrogen receptor-negative/progesterone receptor-positive (ER−/PR+) a real pathological entity?
  10. 850
    “…SIMPLE SUMMARY: Most breast cancers co-express estrogen receptor α (ERα) and progesterone receptor (PgR). These cancers are sensitive to endocrine therapy and, in general, have superior outcomes. …”
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    Lost but Not Least—Novel Insights into Progesterone Receptor Loss in Estrogen Receptor-Positive Breast Cancer
  11. 851
    “…We have characterized oligomeric configurations of the adenosine A2a receptor (A2aR) by combining large-scale molecular dynamics simulations with Markov state models. …”
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    Modulation of adenosine A2a receptor oligomerization by receptor activation and PIP(2) interactions
  12. 852
    por Nema, Rajeev, Patel, Priti, Kumar, Ashok
    Publicado 2021
    “…Despite curative resection, recurrence and metastasis contribute to a high mortality rate in patients with GC. The receptor-tyrosine-kinase-like orphan receptors 1/2 (ROR1/2) are transmembrane proteins belonging to the receptor tyrosine kinase (RTK) family. …”
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    Prognostic Role of Receptor Tyrosine Kinase–Like Orphan Receptors in Intestinal-Type Gastric Cancer
  13. 853
    “…The primary dementia-protective benefits of Angiotensin receptor type 1 (AT1R) blockers (ARBs) are believed to arise from systemic effects on blood pressure. …”
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    Angiotensin Receptor Blockers Upregulate Angiotensin Type 4 Receptor in Brains of Cognitively Intact Individuals
  14. 854
    “…OlfactionBase contains detailed information of components like odors, odorants, and odorless compounds with physicochemical and ADMET properties, olfactory receptors (ORs), odorant- and pheromone binding proteins, OR-odorant interactions in Human and Mus musculus. …”
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    OlfactionBase: a repository to explore odors, odorants, olfactory receptors and odorant–receptor interactions
  15. 855
    “…We review the evidence on opioid receptor expression in cancer, opioid receptor polymorphisms and cancer outcome, the effect of opioid antagonists, especially the peripheral antagonist methylnaltrexone, and lastly, the evidence available of a role for opioids through non-opioid receptor mediated actions.…”
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    Opioid Receptor-Mediated and Non-Opioid Receptor-Mediated Roles of Opioids in Tumour Growth and Metastasis
  16. 856
    por Pardridge, William M.
    Publicado 2021
    “…Biologics can be re-engineered for BBB transport as IgG fusion proteins, where the IgG domain is a monoclonal antibody (MAb) that targets an endogenous BBB transporter, such as the insulin receptor (IR) or transferrin receptor (TfR). The IR and TfR at the BBB transport the receptor-specific MAb in parallel with the transport of the endogenous ligand, insulin or transferrin. …”
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    Kinetics of Blood–Brain Barrier Transport of Monoclonal Antibodies Targeting the Insulin Receptor and the Transferrin Receptor
  17. 857
    “…Insect nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels mainly expressed in the central nervous system of insects. …”
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    Nicotinic acetylcholine receptor modulator insecticides act on diverse receptor subtypes with distinct subunit compositions
  18. 858
    “…We previously reported that DCHP is a potent ligand of the pregnane X receptor (PXR) which acts as a xenobiotic sensor to regulate xenobiotic metabolism. …”
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    Pregnane X Receptor Mediates Atherosclerosis Induced by Dicyclohexyl Phthalate in LDL Receptor-Deficient Mice
  19. 859
    “…Retinoid X receptors (RXRs) present a subgroup of the nuclear receptor superfamily with particularly high evolutionary conservation of ligand binding domain. …”
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    Retinoid X Receptor: Cellular and Biochemical Roles of Nuclear Receptor with a Focus on Neuropathological Involvement
  20. 860
    “…BACKGROUND: Among women, breast cancer is the leading cause of cancer-related death worldwide. Estrogen receptor α-positive (ERα+) breast cancer accounts for 70% of all breast cancer subtypes. …”
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    Activity of Estrogen Receptor β Agonists in Therapy-Resistant Estrogen Receptor-Positive Breast Cancer
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