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881“…Activation of the cholecystokinin type B receptor (CCKBR) by cholecystokinin octapeptide (CCK-8) inhibits opioid analgesia. …”
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882por Al-Zamel, Noura, Al-Sabah, Suleiman, Luqmani, Yunus, Adi, Lobna, Chacko, Siby, Schneider, Tom Dario, Krasel, Cornelius“…We investigated the signaling properties of a recently reported dual-incretin receptor agonist (P18). GLP-1R, GIPR, and the closely related glucagon receptor (GCGR) were expressed in HEK-293 cells. …”
Publicado 2019
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883“…Triagonists of GLP‐1R/ GIPR /GCGR, including SAR441255, bind to each receptor and induce specific effects through each receptor signaling pathway, thus result in weight loss and glycemic control in obese T2D animal models.…”
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884“…RESULTS: Calcification was positively correlated with expression of estrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor (HER)-2. …”
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885Publicado 1984“…Receptors for the third component of complement (C3) on cultured human monocytes (MO) bind ligand-coated particles but do not initiate phagocytosis. …”
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886por Kabir, Farruk M. Lutful, DeInnocentes, Patricia, Agarwal, Payal, Mill, Christopher P., Riese, David J., Bird, R. Curtis“…Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and normal canine mammary epithelial cells were used to investigate expression of the major breast cancer-specific hormone receptors estrogen receptor alpha (ER1) and progesterone receptor (PR) as well as luminal epithelial-specific proto-oncogenes encoding c-erbB-1 (epidermal growth factor receptor/EGFr), c-erbB-2/HER2, c-erbB-3, and c-erbB-4 receptors. …”
Publicado 2017
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887por Oh, Hannah, Eliassen, A. Heather, Beck, Andrew H., Rosner, Bernard, Schnitt, Stuart J., Collins, Laura C., Connolly, James L., Montaser-Kouhsari, Laleh, Willett, Walter C., Tamimi, Rulla M.“…We examined the associations of breast cancer risk factors with estrogen receptor (ER), progesterone receptor (PR), insulin-like growth factor-1 receptor (IGF-1R), and Ki67 expression in normal breast tissue. …”
Publicado 2017
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888por Sankoda, Akiko, Harada, Norio, Kato, Tomoko, Ikeguchi, Eri, Iwasaki, Kanako, Yamane, Shunsuke, Murata, Yuki, Hirasawa, Akira, Inagaki, Nobuya“…GIP is strongly secreted from enteroendocrine K cells by oil ingestion. G protein‐coupled receptor (GPR)120 and GPR40 are two major receptors for long chain fatty acids, and are expressed in enteroendocrine K cells. …”
Publicado 2019
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889por Llanos, Adana A. M., Lin, Yong, Chen, Wenjin, Yao, Song, Norin, Jorden, Chekmareva, Marina A., Omene, Coral, Cong, Lei, Omilian, Angela R., Khoury, Thaer, Hong, Chi-Chen, Ganesan, Shridar, Foran, David J., Higgins, Michael, Ambrosone, Christine B., Bandera, Elisa V., Demissie, Kitaw“…We abstracted data on tumor grade, tumor size, tumor stage, lymph node status, Ki67, estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2) from pathology records, and used ER, PR, and HER2 expression data to classify breast cancer subtype. …”
Publicado 2020
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890por Kadir, Eniola Risikat, Imam, Aminu, Olajide, Olayemi Joseph, Ajao, Moyosore SaliuEnlace del recurso
Publicado 2021
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891por Pivonello, Rosario, Munster, Pamela N., Terzolo, Massimo, Ferrigno, Rosario, Simeoli, Chiara, Puglisi, Soraya, Bali, Utsav, Moraitis, Andreas G.“…Somatostatin exhibits an inhibitory effect on pituitary hormone secretion, including inhibition of growth hormone and adrenocorticotropic hormone (ACTH), and it can have antisecretory and antitumor effects on neuroendocrine tumors (NETs) that express somatostatin receptors. Although the precise mechanism remains unclear, the finding that glucocorticoids downregulate somatostatin receptor subtype 2 (SSTR2) expression has been used to explain the lack of efficacy of traditional SSTR2-targeting analogs in patients with ACTH-secreting NETs. …”
Publicado 2022
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892por Alsughayer, Anas M., Dabbagh, Tamara Z., Abdel-Razeq, Rashid H., Al-Jussani, Ghada N., Alhassoon, Salam, Sughayer, Maher A.“…Estrogen receptors (ERs), progesterone receptors (PRs), and human epidermal growth factor receptor 2 (HER2) are the mainstay of breast cancer management, and their prevalence rates vary among different populations possibly related to ethnic/genetic and/or socioeconomic status. …”
Publicado 2022
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893“…Our findings revealed the presence of an insulin-like growth factor type 1 receptor (IGF-1R) in ark clams, which was capable of binding to SbFn and was named SbIGF-1R. …”
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894por Fu, Ping, Mei, Yu-Shuo, Liu, Wei‑Jia, Chen, Ping, Jin, Qing-Chun, Guo, Shi‑Qi, Wang, Hui‑Ying, Xu, Ju‑Ping, Zhang, Yan-Chu-Fei, Ding, Xue‑Ying, Liu, Cui-Ping, Liu, Cheng-Yi, Mao, Rui-Ting, Zhang, Guo, Jing, Jian“…In contrast, elevenin without the disulfide bond could not activate the receptors, indicating that the disulfide bond is required for receptor activity. …”
Publicado 2023
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895por Golonka, Rachel M., Yeoh, Beng San, Saha, Piu, Gohara, Amira, Tummala, Ramakumar, Stepkowski, Stanislaw, Tiwari, Amit K., Joe, Bina, Gonzalez, Frank J., Gewirtz, Andrew T., Vijay-Kumar, Matam“…METHODS: To better understand the role of gut microbiota in HCC, mice deficient of toll-like receptor 5 (TLR5, a receptor for bacterial flagellin) as a model of spontaneous gut microbiota dysbiosis were crossed with farnesoid X receptor knockout mice (FxrKO), a genetic model for spontaneous HCC. …”
Publicado 2023
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897por Golubeva, Elena A., Lavrov, Mstislav I., Veremeeva, Polina N., Vyunova, Tatiana V., Shevchenko, Konstantin V., Topchiy, Maxim A., Asachenko, Andrey F., Palyulin, Vladimir A.“…The structures of the compounds contain tricyclic cage and indane fragments necessary for binding with the target receptor. Their physiological activity was studied by radioligand-receptor binding analysis using [(3)H]PAM-43 as a reference ligand, which is a highly potent positive allosteric modulator of AMPA receptors. …”
Publicado 2023
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898por Zhao, Zhennan, Xie, Yufeng, Bai, Bin, Luo, Chunliang, Zhou, Jingya, Li, Weiwei, Meng, Yumin, Li, Linjie, Li, Dedong, Li, Xiaomei, Li, Xiaoxiong, Wang, Xiaoyun, Sun, Junqing, Xu, Zepeng, Sun, Yeping, Zhang, Wei, Fan, Zheng, Zhao, Xin, Wu, Linhuan, Ma, Juncai, Li, Odel Y., Shang, Guijun, Chai, Yan, Liu, Kefang, Wang, Peiyi, Gao, George F., Qi, Jianxun“…Additionally, BA.2.75 is significantly increasing in some countries. Exploring their receptor binding and interspecies transmission risk is urgently needed. …”
Publicado 2023
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900por Hümmert, Martin W., Jendretzky, Konstantin F., Fricke, Karin, Gingele, Marina, Ratuszny, Dominica, Möhn, Nora, Trebst, Corinna, Skripuletz, Thomas, Gingele, Stefan, Sühs, Kurt-Wolfram“…The clinical implications of the presence of anti-N-methyl-D-aspartate receptor (NMDAR)-specific intrathecal immunoglobulin G synthesis and whether it determines the diagnosis of anti-NMDAR encephalitis have not been thoroughly investigated yet. …”
Publicado 2023
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