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941por Dulos, John, Vijn, Peter, van Doorn, Cindy, Hofstra, Claudia L, Veening-Griffioen, Desiree, de Graaf, Jan, Dijcks, Fred A, Boots, Annemieke MH“…Estrogens bind both estrogen receptor (ER)α and β. The contribution of ERα and ERβ to ER-mediated immune modulation was studied in delayed type hypersensitivity (DTH) and in experimental arthritis METHODS: ER-mediated suppression of rat adjuvant arthritis (AA) was studied using ethinyl-estradiol (EE) and a selective ERβ agonist (ERB-79). …”
Publicado 2010
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942“…It is plausible that they use olfactory receptors to detect water-soluble compounds. How the zebra fish Danio Rerio, an organism with only 98 functional olfactory receptors, is able to selectively detect and recognize numerous compounds in water remains a puzzling phenomenon. …”
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943“…The estrogen receptor-related receptors (ERRs) are a group of nuclear receptors that were originally identified on the basis of sequence similarity to estrogen receptors. …”
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944por Lee, Henry H.C., Deeb, Tarek Z., Walker, Joshua A., Davies, Paul A., Moss, Stephen J.“…KCC2 is a neuron-specific K(+)-Cl(−) cotransporter that maintains a low intracellular Cl(−) concentration essential for hyperpolarizing inhibition mediated by GABA(A) receptors. Deficits in KCC2 activity occur in disease states associated with pathophysiological glutamate release. …”
Publicado 2011
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945por Delsing, Dianne J.M, Leijten, Frank P, Arts, Karin, van Eenennaam, Hans, Garritsen, Anja, Gijbels, Marion J.J, de Winther, Menno P.J, van Elsas, Andrea“…OBJECTIVE: The cannabinoid receptor 2 (CB2) has been implicated to play a role in various inflammatory processes. …”
Publicado 2011
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946“…The aims of this study were to determine the expression of leptin, leptin receptor (ObR), adiponectin and adiponectin receptor (AdipoR) in human breast cancer, to evaluate their prognostic significance in the breast cancer. …”
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947por Guggino, Giuliana, Giardina, Anna Rita, Ciccia, Francesco, Triolo, Giovanni, Dieli, Francesco, Sireci, Guido“…In this paper we focus our attention on the role of two families of receptors, Toll-like receptors (TLR) and decoy receptors (DcR) involved in the generation of systemic lupus erythematosus (SLE) and lupus-like syndromes in human and mouse models. …”
Publicado 2012
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948“…Here we report the study of two bioengineered variants of human trace amine-associated receptor 5 (hTAAR5) that were expressed in stable tetracycline-inducible HEK293S cell lines. …”
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949A Hepatocyte Growth Factor Receptor (Met)–Insulin Receptor hybrid governs hepatic glucose metabolismpor Fafalios, Arlee, Ma, Jihong, Tan, Xinping, Stoops, John, Luo, Jianhua, DeFrances, Marie C., Zarnegar, Reza“…Met is the transmembrane tyrosine kinase cell surface receptor for Hepatocyte Growth Factor (HGF) and is related to the insulin receptor (INSR) tyrosine kinase. …”
Publicado 2011
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950“…Infection with EV71 is occasionally associated with severe neurological diseases such as acute encephalitis, acute flaccid paralysis, and cardiopulmonary failure. Because cellular receptors for viruses play an important role in cell, tissue, and species tropism, it is important to identify and characterize the receptor molecule. …”
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951
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952“…The retinoic acid receptor-related orphan receptor α (RORα) is a member of the nuclear receptor superfamily of transcription factors that plays an important role in regulation of the circadian rhythm and metabolism. …”
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954“…Among the XenoRs in the reporter screening assay, TCC promotes both constitutive androstane receptor (CAR) and estrogen receptor alpha (ERα) activities. …”
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955“…A combined modeling approach was used to identify structural factors that underlie the structure–activity relationships (SARs) of full dopamine D(2) receptor agonists and structurally similar inactive compounds. …”
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956por Morairty, Stephen R., Revel, Florent G., Malherbe, Pari, Moreau, Jean-Luc, Valladao, Daniel, Wettstein, Joseph G., Kilduff, Thomas S., Borroni, Edilio“…The hypocretin (orexin) system is involved in sleep/wake regulation, and antagonists of both hypocretin receptor type 1 (HCRTR1) and/or HCRTR2 are considered to be potential hypnotic medications. …”
Publicado 2012
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957por Davies, John, Heeb, Heather, Garimella, Rama, Templeton, Kimberly, Pinson, David, Tawfik, Ossama“…Upon activation, vitamin D receptors (VDRs) combine with retinoid receptor (RXR) forming a heterodimer initiating a cascade of events. …”
Publicado 2012
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958por Woo, Seung Kyoon, Kwon, Min Seong, Ivanov, Alexander, Gerzanich, Volodymyr, Simard, J. Marc“…The sulfonylurea receptor 1 (Sur1)-NC(Ca-ATP) channel plays a central role in necrotic cell death in central nervous system (CNS) injury, including ischemic stroke, and traumatic brain and spinal cord injury. …”
Publicado 2013
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959por Lenhard, Miriam, Tereza, Lennerová, Heublein, Sabine, Ditsch, Nina, Himsl, Isabelle, Mayr, Doris, Friese, Klaus, Jeschke, Udo“…Interestingly, median receptor expression for ER-α and PR-A/-B was significantly higher in G1 vs. …”
Publicado 2012
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