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  1. 1061
    “…Furthermore, the P2X receptor-mediated CSR responses were enhanced by intrapericardial naloxone, a specific opioid receptor antagonist. …”
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    Role of opioid receptors in modulation of P2X receptor-mediated cardiac sympathoexcitatory reflex response
  2. 1062
    “…The vasoprotective effects of C‐type natriuretic peptide are somewhat mediated by the natriuretic peptide receptor C, suggesting that this receptor represents a novel therapeutic target for the treatment of cardiovascular diseases. …”
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    Biophysical screening methods for extracellular domain peptide receptors, application to natriuretic peptide receptor C ligands
  3. 1063
    “…Here, we aimed to elucidate a role of adenosine receptors (ARs) in mediating guanosine effects. We investigated the neuroprotective effects of guanosine in hippocampal slices from A(2A)R-deficient mice (A(2A)R(−/−)) subjected to oxygen/glucose deprivation (OGD). …”
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    Adenosine A(1)-A(2A) Receptor-Receptor Interaction: Contribution to Guanosine-Mediated Effects
  4. 1064
    “…Interestingly, CHK1 inhibition showed the single-agent antitumor activity in ER(+)/PR(+)/HER2(-) breast cancer which was mediated by the cyclin dependent kinase inhibitor 1A (p21), kinesin family member 11 (Eg5) and cell surface death receptor (Fas). Conclusions: CHK1's variable role determines the application of CHK1 inhibition in breast cancer with ER/PR heterogeneity.…”
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    The Role of CHK1 Varies with the Status of Oestrogen-receptor and Progesterone-receptor in the Targeted Therapy for Breast Cancer
  5. 1065
    por Schneider, Erich H., Seifert, Roland
    Publicado 2017
    “…Thus, the four human histamine receptor subtypes were analyzed side-by-side in the Sf9 insect cell expression system, using radioligand binding assays as well as functional readouts proximal to the receptor activation event (steady-state GTPase assays and [(35)S]GTPγS assays). …”
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    Pharmacological Characterization of Human Histamine Receptors and Histamine Receptor Mutants in the Sf9 Cell Expression System
  6. 1066
    “…Efficient Ca(2+) flux induced during cognate T cell activation requires signaling the T cell receptor (TCR) and unidentified G-protein-coupled receptors (GPCRs). …”
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    Neurokinin-1 Receptor Signaling Is Required for Efficient Ca(2+) Flux in T-Cell-Receptor-Activated T Cells
  7. 1067
    “…Androgen receptor (AR) plays a central role in PCa, even in advanced “castrate-resistant” disease. …”
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    Carbidopa suppresses prostate cancer via aryl hydrocarbon receptor-mediated ubiquitination and degradation of androgen receptor
  8. 1068
    “…Background and Aims: In primary biliary cholangitis (PBC), antibodies to a peptide of the muscarinic acetylcholine receptor 3 (mAChR3) have been described. Since the mAChR3 is expressed on cholangiocytes and mAChR3-signaling is involved in the pathogenesis of chronic inflammatory biliary diseases, we wanted to investigate whether anti-mAChR3-antibodies influence the function of the receptor and the proliferative response of cholangiocytes. …”
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    Antibodies to the Muscarinic Acetylcholine Receptor M3 in Primary Biliary Cholangitis Inhibit Receptor Function on Cholangiocytes
  9. 1069
    “…The B cell receptor (BCR) pathway has been identified as a potential therapeutic target in a number of common B cell malignancies, including chronic lymphocytic leukemia, diffuse large B cell lymphoma, Burkitt lymphoma, follicular lymphoma, mantle cell lymphoma, marginal zone B cell lymphoma, and Waldenstrom’s macroglobulinemia. …”
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    Mechanisms of B Cell Receptor Activation and Responses to B Cell Receptor Inhibitors in B Cell Malignancies
  10. 1070
    “…The opioid receptors are a family of G-protein coupled receptors (GPCRs) with close structural homology. …”
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    Targeting opioid receptor signaling in depression: do we need selective κ opioid receptor antagonists?
  11. 1071
    “…We investigated whether estrogen receptor (ER)/progestogen receptor (PR) status is correlated with (18)F-FDG uptake, and whether (18)F-FDG PET/CT could be useful for predicting ER/PR status in endometrial cancer. …”
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    Relationship between the expression of oestrogen receptor and progesterone receptor and (18)F-FDG uptake in endometrial cancer
  12. 1072
    “…The current COVID-19 pandemic is caused by the SARS-CoV-2 betacoronavirus, which utilizes its highly glycosylated trimeric Spike protein to bind to the cell surface receptor ACE2 glycoprotein and facilitate host cell entry. …”
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    Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor
  13. 1073
    “…The SARS-CoV-2 betacoronavirus uses its highly glycosylated trimeric Spike protein to bind to the cell surface receptor angiotensin converting enzyme 2 (ACE2) glycoprotein and facilitate host cell entry. …”
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    Virus-Receptor Interactions of Glycosylated SARS-CoV-2 Spike and Human ACE2 Receptor
  14. 1074
    “…Receptor usage that determines cell tropism and drives viral classification closely correlates with the virus structure. …”
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    Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage
  15. 1075
    “…RESULTS: ITGA8 was expressed at low levels in human breast cancer cells compared to non-tumorigenic breast cells and breast tissue, and was upregulated in estrogen receptor (ER)-positive tissue compared with ER-negative tissue (P<0.01). …”
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    Estrogen receptor α is involved in the regulation of ITGA8 methylation in estrogen receptor-positive breast cancer
  16. 1076
    “…BACKGROUND: For prostate cancer, signaling pathways induced by over-boarding stimulation of G-protein coupled receptors (GPCR) such as the endothelin, α1- and β-adrenergic, muscarinic and angiotensin 1 receptors were accused to support the carcinogenesis. …”
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    Autoantibodies directed against α1-adrenergic receptor and endothelin receptor A in patients with prostate cancer
  17. 1077
    “…The (pro)renin receptor [(P)RR] is a multifunctioning protein playing roles in various pathological conditions. …”
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    Adrenal (Pro)renin Receptor Expression and Serum Soluble (Pro)renin Receptor Concentration in Primary Aldosteronism
  18. 1078
    “…Hence, a therapeutic value of VNS with respect to SARS-CoV-2 infection risk through ACE2 receptor modulation in intestinal epithelia could not be established.…”
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    The role of nicotinic receptors in SARS-CoV-2 receptor ACE2 expression in intestinal epithelia
  19. 1079
    “…Patients with neuroendocrine tumors (NETs) can be treated with peptide receptor radionuclide therapy (PRRT). Here, the somatostatin analogue octreotate radiolabeled with lutetium-177 is targeted to NET cells by binding to the somatostatin receptor subtype 2 (SST(2)). …”
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    Inter and intra-tumor somatostatin receptor 2 heterogeneity influences peptide receptor radionuclide therapy response
  20. 1080
    por Gohar, Eman Y., Pollock, David M.
    Publicado 2021
    “…The G protein–coupled estrogen receptor 1 (GPER1) mediates rapid estrogenic signaling. …”
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    Functional Interaction of Endothelin Receptors in Mediating Natriuresis Evoked by G Protein–Coupled Estrogen Receptor 1
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