“…Tumor cells may express receptors for APN. Cellular signaling is the mechanism by which APN exerts its host-protective responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…N-Methyl-d-aspartate (NMDA) receptors play a variety of physiologic roles and their proper signaling is essential for cellular homeostasis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…G-protein coupled receptors (GPCRs), the largest family of membrane signaling proteins, respond to neurotransmitters, hormones and small environmental molecules. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent finding of various thyroid hormone receptors (TR) isoforms and their differential pattern of tissue distribution has regained interest in possible use of TH analogues in therapeutics. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The vitamin D receptor (VDR) is a nuclear, ligand-dependent transcription factor that in complex with hormonally active vitamin D, 1,25(OH)(2)D(3), regulates the expression of more than 900 genes involved in a wide array of physiological functions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The growth hormone secretagogue-receptor (GHS-R) was discovered in humans and pigs in 1996. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Muscarinic acetylcholine receptors, which comprise five subtypes (M(1)-M(5) receptors), are expressed in both the CNS and PNS (particularly the target organs of parasympathetic neurons). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In the course of elucidating the mechanism underlying these actions, we discovered that bile acids interact functionally with intestinal muscarinic receptors. The present communication reviews muscarinic receptor expression in normal and neoplastic colon epithelium, the role of autocrine signaling following synthesis and release of acetylcholine from colon cancer cells, post-muscarinic receptor signaling including the role of transactivation of epidermal growth factor receptors and activation of the ERK and PI3K/AKT signaling pathways, the structural biology and metabolism of bile acids and evidence for functional interaction of bile acids with muscarinic receptors on human colon cancer cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Previously, we identified significant changes in the expression pattern of LT receptors in the gastric mucosa after eradication of Helicobacter pylori infection. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our view of endocytosis and membrane trafficking of transmembrane receptors has dramatically changed over the last 20 years. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent discoveries indicate that many G-protein coupled receptors (GPCRs) and channels involved in pain modulation are able to form receptor heteromers. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review focuses on the role of platelet receptors in human physiology. Data were extracted from peer-reviewed journals using MEDLINE and EMBASE databases, and the following terms (platelets, platelet receptors, CD markers, integrins, tetraspanins, transmembrane receptors, prostaglandin receptors, immunoglobulin superfamily receptors) were used.…”
Enlace del recurso
Enlace del recurso

“…Direct targeting of the NMDA receptor could result in more rapid antidepressant effects. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent researchers, in an attempt to clarify some aspects of the underlying pathways, provide convincing evidence that GCs induce effects that are dependent upon the glucocorticoid-receptor (GR)-mediated transcriptional regulation of specific genes known to play key roles in cellular/tissue functions, including growth, apoptosis, differentiation, metastasis and cell survival. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Nucleotide-binding oligomerization domain-like receptors (NLRs) represent a group of key sensors for microbes and damage in the lung. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Chemokines and their receptors are also potential biomarkers of both disease activity and response to treatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The function of steroid receptors is not only regulated by steroid hormones, but also by multiple cellular signaling cascades activated by membrane-bound receptors which are stimulated by growth factors or cytokines. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Studies of the role of chemokine receptors, a family of proteins belonging to the group of G protein-coupled receptors, in ovarian carcinoma strongly placed this family of membrane receptors as major regulators of progression of this malignancy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso