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  1. 149681
    “…RESULTS: AHR activation, reflected by the expression of Cyp1a1 and Cyp1a2, two major AHR target genes, was deeply reduced in all models (C26 and BaF3, P < 0.001; MC38 and APC(Min/+), P < 0.05) independently of anorexia. …”
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    Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia
  2. 149682
    “…This study aimed to examine the metabolic and perfusion function changes in the paraspinal muscles of patients with CLBP as indirectly reflected by blood oxygen level–dependent (BOLD) imaging and T2 mapping. …”
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    Functional magnetic resonance imaging reveals dysfunction of the paraspinal muscles in patients with chronic low back pain: a cross-sectional study
  3. 149683
    “…Therapeutic target attainment was erratic, but reflective of the literature.(1) Optimized dosing is required for specific neonatal subgroups.…”
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    P30 Evaluating vancomycin continuous infusion protocol compliance and gauging therapeutic target attainment in neonates
  4. 149684
    “…The study also offers reflections on the importance of clarity of intended meaning within the SOP documents.…”
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    Understanding the scope of practice of physician associate/physician associate comparable professions using the World Health Organization global competency and outcomes framework for universal health coverage
  5. 149685
    “…Of the beneficiaries, 7730 were male and 15 304 were female, 3057 were Black, 19 351 were White, 447 were of other race or ethnicity (assessed according to the Centers for Medicare & Medicaid Services beneficiary race and ethnicity code, which reflects data reported to the Social Security Administration), and 179 were of unknown race and ethnicity. …”
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    Association Between a Bundled Payment Program for Lower Extremity Joint Replacement and Patient Outcomes Among Medicare Advantage Beneficiaries
  6. 149686
    “…Controlling for covariates, odds of willingness to facilitate abortion care in every scenario decreased with every one-point increase in SABAS score (reflecting more stigmatizing attitudes), and odds of obstructing abortion care increased with every one-point increase in SABAS score. …”
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    Stigma towards women requesting abortion and association with health facility staff facilitation and obstruction of abortion care in South Africa
  7. 149687
    “…While self-identified racial groups rated the breasts similar relative to one another, there were distinct differences in numerical ratings that may be reflective of broader, more generalized sentiments and preferences that were not able to be captured by our survey instrument. …”
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    Differential Preferences in Breast Aesthetics by Self-identified Racial Demographics Assessed on a National Survey
  8. 149688
    “…RESULTS: Patients with triple negative breast cancers (TNBCs) exhibited the lowest number of EVs in the sera; whilst the highest was detected in ER+HER2+ cancers; reflected also in the higher level of CD63+ vesicles found within the ER+HER2+ local tumour microenvironment. …”
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    Serum-derived extracellular vesicles from breast cancer patients contribute to differential regulation of T-cell-mediated immune-escape mechanisms in breast cancer subtypes
  9. 149689
    “…Regulators have positioned the best practice standard of evidence as an interventional study with a comparator reflective of standard care, often operationalized as a pragmatic trial. …”
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    Differences Between Online Trial Participants Who Have Used Statutory Mental Health Services and Those Who Have Not: Analysis of Baseline Data From 2 Pragmatic Trials of a Digital Health Intervention
  10. 149690
    “…Importantly, culturing OAC patient-derived PBMCs under dual hypoxia and glucose deprivation, reflective of the conditions within the hostile TME, upregulated an array of ICs on the surface of T cells including PD-1, CTLA-4, A2aR, PD-L1 and PD-L2 and decreased expression of IFN-γ by T cells. …”
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    Nutrient deprivation and hypoxia alter T cell immune checkpoint expression: potential impact for immunotherapy
  11. 149691
    “…CONCLUSIONS AND RELEVANCE: Changes in native T1 in response to treatment, reflecting a composite of changes in T2 and ECV, are associated with in changes in traditional markers of cardiac response and associated with mortality. …”
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    Tracking Treatment Response in Cardiac Light-Chain Amyloidosis With Native T1 Mapping
  12. 149692
    “…The algorithm selected session types for each patient each week, with the goal of minimizing OA risk, defined in terms of a dynamic score reflecting patient reports during IVR monitoring calls. …”
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    An Automatically Adaptive Digital Health Intervention to Decrease Opioid-Related Risk While Conserving Counselor Time: Quantitative Analysis of Treatment Decisions Based on Artificial Intelligence and Patient-Reported Risk Measures
  13. 149693
    “…Although these agents differ in cost and labeled dosing, it is unclear whether these differences are reflected in clinical practice. OBJECTIVE: To compare the real-world frequency and cost of ranibizumab and aflibercept injections among treatment-naive and previously treated patients with nAMD and DME. …”
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    Real-World Injection Frequency and Cost of Ranibizumab and Aflibercept for the Treatment of Neovascular Age-Related Macular Degeneration and Diabetic Macular Edema
  14. 149694
    “…SSM/PCA could differentiate iRBD from DLB, reflecting specifically the differences in disease staging and severity (AUC: 0.938, specificity: 0.821, sensitivity 0.941). …”
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    Comparison of univariate and multivariate analyses for brain [18F]FDG PET data in α-synucleinopathies
  15. 149695
    “…DATA SOURCES: Eight databases searched from 1 January 2000 to 1 February 2023, reflecting recent perinatal care, and references of screened articles. …”
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    The proportions of term or late preterm births after exposure to early antenatal corticosteroids, and outcomes: systematic review and meta-analysis of 1.6 million infants
  16. 149696
    “…After 3 years, ivermectin 1% cream QD was associated with the lowest health care costs ($62,767 compared with $73,284 for metronidazole 0.75% cream BID and $77,208 for azelaic acid 15% gel BID), reflecting a 15% reduction in physician visit costs, when compared with metronidazole 0.75% cream BID, and almost a 20% reduction, when compared with azelaic acid 15% gel BID. …”
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    Cost-Effectiveness of Ivermectin 1% Cream in Adults with Papulopustular Rosacea in the United States
  17. 149697
    “…We also use this study as a basis to radiate the work of municipal basic public health services centered on the region and the outstanding problems reflected and to provide theoretical contents and suggestions that can be referred to for the same regions in central and western China as well as worldwide. …”
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    Evaluation of community basic public health service effect in a city in Inner Mongolia Autonomous Region——based on entropy weight TOPSIS method and RSR fuzzy set
  18. 149698
    “…SIMPLE SUMMARY: The monitoring of the minimal residual disease (MRD) in Chronic Myeloid Leukemia is a key element in the management of affected patients because it reflects the response to therapy and allows for the selection of the best responders who may benefit from the suspension of the therapy. …”
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    Minimal Residual Disease Detection at RNA and Leukemic Stem Cell (LSC) Levels: Comparison of RT-qPCR, d-PCR and CD26+ Stem Cell Measurements in Chronic Myeloid Leukemia (CML) Patients in Deep Molecular Response (DMR)
  19. 149699
    “…DP was expressed as a dichotomous variable at the day level (DP day vs non-DP day) and as a continuous variable reflecting the percent of days DP was experienced on a valid day. …”
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    Exploring the Impact of Dawn Phenomenon on Glucose-Guided Eating Thresholds in Individuals With Type 2 Diabetes Using Continuous Glucose Monitoring: Observational Study
  20. 149700
    “…As expected, hemorrhage resulted in smaller P-V loops, reflective of decreased preload and afterload conditions; however, the cardiac output and heart rate were preserved. …”
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    Investigating the variability in pressure–volume relationships during hemorrhage and aortic occlusion
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