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  1. 150061
    por Patel, Samir, Al-Shakarchi, Israa
    Publicado 2019
    “…There has been no large-trial convincing evidence of methotrexate efficacy in GCA at introduction or for relapses and this is reflected in the national guidance. However, the trials above used relatively low doses of methotrexate. …”
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  2. 150062
    por Onac, Ioana, Hajela, Vijay
    Publicado 2019
    “…The scalp necrosis, on reflection was due to an ongoing vasculitis that was being undertreated. …”
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  3. 150063
    “…These include: (1) primary inefficient transmission via sexual and transplacental routes but effective transmission via blood; (2) primary replication in renewable populations of lymphoidal cells with production of large amounts of virus after the initial infection of the host followed by persistent low level of viremia in spite of antiviral immune responses; (3) persistence, reflecting continuous rounds of productive, cytocidal infection of permissive cells [59, 74] and the rate of generation of permissive cells which may be the main factor in determining the level of virus production (in the case of HIV, the rate of activation of CD4(+) T cells to support a productive HIV replication might be the factor determining the rate of virus production and the progression of the disease); (4) rapid antibody formation but delayed production of neutralizing antibodies with limited neutralizing capacity; (5) rapid but transient generation of virus-specific CTLs; and (6) accumulation of large amounts of virus in newly formed germinal centers in the spleen and lymph nodes concomitant with an initiation of a permanent polyclonal activation of B cells resulting in an elevation of plasma IgG2a. …”
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  4. 150064
    por Ark, Rajiv
    Publicado 2020
    “…Dose changes later in treatment fluctuated, reflecting a balancing act between disease recurrence and side effects of long-term steroids. …”
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  5. 150065
  6. 150066
  7. 150067
    “…PE, DVT and VTE proportions reported in the smaller studies (with much wider confidence intervals) were typically three or more times as high as those reported in the larger studies as reflected in a funnel plot (Figure) and Table. Conclusion Our comprehensive review revealed incidences of PE, DVT and VTE among hospitalized COVID-19 patients that are comparable to hospitalized patients without COVID-19. …”
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  8. 150068
    “…The rate of the propagation phase of thrombin generation (MRI) and the Peak of thrombin were significantly decrease and the lag-time was prolonged reflecting the antithrombotic effect of treatment with LMWH. …”
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  9. 150069
    “…The policy actors should consider the preferences of the KPs and the key influencers in reducing barriers to communication and increasing the uptake of PrEP and HIVST services; ensure it reflects in a tailored communication strategy. Since multi-linguistics and multi-channels of presentation were enablers to acquiring PrEP and HIVST messages, the communications strategy for HIV prevention should incorporate these recommendations and adapt to context-specific approaches for effective messaging.…”
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  10. 150070
    “…As shown in Figure 2, a significant downward trend (p<0.04) was noted in non-infused products by domestic TCs (p<0.02), but not international TCs, most likely reflecting low volume from the international TCs. In the study cohort, we were also able to analyze the effect of COVID-19 on product infusion. …”
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  11. 150071
    por Rimmer, Michael P, Howie, Ruth A, Anderson, Richard A, Barratt, Christopher L R, Barnhart, Kurt T, Beebeejaun, Yusuf, Bertolla, Ricardo Pimenta, Bhattacharya, Siladitya, Björndahl, Lars, Bortoletto, Pietro, Brannigan, Robert E, Cantineau, Astrid E P, Caroppo, Ettore, Collura, Barbara L, Coward, Kevin, Eisenberg, Michael L, De Geyter, Christian, Goulis, Dimitrios G, Henkel, Ralf R, Ho, Vu N A, Hussein, Alayman F, Huyser, Carin, Kadijk, Jozef H, Kamath, Mohan S, Khashaba, Shadi, Kobori, Yoshitomo, Kopeika, Julia, Kucuk, Tansu, Luján, Saturnino, Matsaseng, Thabo Christopher, Mathur, Raj S, McEleny, Kevin, Mitchell, Rod T, Mol, Ben W, Murage, Alfred M, Ng, Ernest H Y, Pacey, Allan, Perheentupa, Antti H, Du Plessis, Stefan, Rives, Nathalie, Sarris, Ippokratis, Schlegel, Peter N, Shabbir, Majid, Śmiechowski, Maciej, Subramanian, Venkatesh, Sunkara, Sesh K, Tarlarzis, Basil C, Tüttelmann, Frank, Vail, Andy, van Wely, Madelon, Vazquez-Levin, Mónica H, Vuong, Lan N, Wang, Alex Y, Wang, Rui, Zini, Armand, Farquhar, Cindy M, Niederberger, Craig, Duffy, James M N
    Publicado 2022
    “…These outcomes will be entered into a modified Delphi method. Repeated reflection and re-scoring should promote convergence towards consensus outcomes, which will be prioritized during a consensus development meeting to identify a final core outcome set. …”
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  12. 150072
    “…The clinical overlap between the congenital disorders of autophagy and these conditions reflects the multiple roles of the proteins and/or emerging molecular connections between the pathways implicated and suggests an exciting area for future research. …”
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  13. 150073
    “…DESIGN, SETTING, AND PARTICIPANTS: This cohort study used national survey data from the Health and Retirement Study linked with Medicare and Medicaid claims that reflected a range of socioeconomic, health, and psychosocial characteristics. …”
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  14. 150074
  15. 150075
    por Fang, Da, Liu, Jiefang
    Publicado 2022
    “…Self control was negatively correlated with emotion perception, emotion evaluation, emotion control and emotion regulation reflection (P < 0.01), negatively correlated with emotion regulation self-efficacy (P < 0.05), and had no correlation with applied emotion strategies. …”
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  16. 150076
  17. 150077
    “…It was also noted that reference to pain was made in the context of case discussions (reflective learning practice) and formative assessments (Applied Knowledge Test, Clinical Skills and Workplace Based Assessments). …”
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  18. 150078
    “…It is possible that pre-HCT CMV-specific humoral immunity as measured by VirScan is reflective of the burden of latent CMV or that CMV-specific antibodies may mediate antibody-dependent enhancement after HCT and thus facilitate reactivation. …”
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  19. 150079
  20. 150080
    “…Consistent with the hypothesis that Eτ+/AD(signature)– status reflects an early stage of AD, Eτ+/AD(signature)– subjects deteriorated significantly faster than Eτ–/AD(signature)– subjects, but significantly slower than Eτ+/AD(signature)+ subjects, on most measures (i.e., change in AD(signature) SUVr, Eτ ROI cortical thickness, and MMSE). …”
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