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  1. 47341
    “…In muscle biopsies from patients with polymyositis or sporadic inclusion body myositis, osmolyte pathway activation was observed in regenerating muscle fibers. In addition, the osmolyte carriers SLC5A3 and SLC6A12 localized to subsets of immune cells, most notably to the endomysial macrophages and T-cells. …”
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    Induction of Osmolyte Pathways in Skeletal Muscle Inflammation: Novel Biomarkers for Myositis
  2. 47342
    “…This study investigated whether young BM stem cells can regenerate and repair the aged retina after acute I/R injury. …”
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    Young bone marrow Sca‐1 cells protect aged retina from ischaemia‐reperfusion injury through activation of FGF2
  3. 47343
    “…‘Holsteiner Cox (HC)’ and ‘Gala’ via Agrobacterium-mediated transformation. The regenerated shoots were selected on kanamycin containing media. …”
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    Metabolic engineering of apple by overexpression of the MdMyb10 gene
  4. 47344
    “…Combination of stem cell technology and 3D biofabrication approaches provides physiological similarity to in vivo tissues and the capability of repairing and regenerating damaged human tissues. Mesenchymal stem cells (MSCs) have been widely used for regenerative medicine applications because of their immunosuppressive properties and multipotent potentials. …”
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    Serum-Free Manufacturing of Mesenchymal Stem Cell Tissue Rings Using Human-Induced Pluripotent Stem Cells
  5. 47345
    “…Over-proliferating Rheb1-deficient hematopoietic stem cells were severely impaired in functional repopulation assays, and they failed to regenerate the blood system when challenged with hematopoietic ablation by sublethal irradiation. …”
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    Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo
  6. 47346
    “…Although α-smooth muscle actin mRNA levels increased 200-fold in the tissue, no myofibroblasts were detected in the regenerating tissue. In vitro, human gingival fibroblast adhesion on periostin, but not collagen, was inhibited by blocking β1 integrins. …”
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    Fibronectin synthesis, but not α-smooth muscle expression, is regulated by periostin in gingival healing through FAK/JNK signaling
  7. 47347
    “…HA‐SAM‐treated wounds had thicker regenerated skin, increased total number of blood vessels, and greater numbers of proliferating keratinocytes within the epidermis. …”
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    Solubilized Amnion Membrane Hyaluronic Acid Hydrogel Accelerates Full‐Thickness Wound Healing
  8. 47348
    “…The star polymer with well-defined triblock arms was synthesized by combining activator regenerated by electron-transfer atom-transfer radical polymerization with ring-opening polymerization. …”
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    Co-Delivery of Imiquimod and Plasmid DNA via an Amphiphilic pH-Responsive Star Polymer that Forms Unimolecular Micelles in Water
  9. 47349
    por Rose, Ray J.
    Publicado 2019
    “…Medicago truncatula is now widely regarded as a legume model where there is an increasing range of genomic resources. Highly regenerable lines have been developed from the wild-type Jemalong cultivar, most likely due to epigenetic changes. …”
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    Somatic Embryogenesis in the Medicago truncatula Model: Cellular and Molecular Mechanisms
  10. 47350
    “…However, the dominant regenerating sub-clone in 9/10 cases was NPM1(+) and this sub-clone was either dominant or minor in the diagnostic sample from which it was derived. …”
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    Single cell analysis of clonal architecture in acute myeloid leukaemia
  11. 47351
    por Marioli, Maria, Kok, Wim Th.
    Publicado 2019
    “…We conducted a systematic study with five globular proteins of different molecular weight (36.7–669 kDa) and isoelectric point (4.0–6.5), and ultrafiltration membranes that are commonly used in aqueous AF4, regenerated cellulose (RC) and polyethersulfone (PES). …”
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    Recovery, overloading, and protein interactions in asymmetrical flow field-flow fractionation
  12. 47352
    “…Ceramic materials mimic the mineral composition of native bone and feature osteoconductive properties; they are therefore used to regenerate bone tissue. Much research focuses on increasing the porosity and pore interconnectivity of ceramic scaffolds to increase osteoconductivity, cell migration and cell-cell interaction. …”
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    Development, Characterization and In Vitro Biological Properties of Scaffolds Fabricated From Calcium Phosphate Nanoparticles
  13. 47353
    “…Thus, in addition to their regenerating potential, their interest has been extended to their possible use in cell therapy strategies for treatment of immune disorders. …”
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    RNA sequencing of mesenchymal stem cells reveals a blocking of differentiation and immunomodulatory activities under inflammatory conditions in rheumatoid arthritis patients
  14. 47354
    “…Flow cytometry was used to assess the ploidy of regenerated shoots. Treatment with 20–40 μM oryzalin produced the highest number of tetraploids. …”
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    Polyploidization for the Genetic Improvement of Cannabis sativa
  15. 47355
    “…Remodeling metabolic pathways to regenerate new vulnerabilities in endocrine resistant breast tumors is novel, and given the need for better strategies to improve therapy response in relapsed ERα (+) tumors, our findings show great promise for uncovering the role that ERα-XPO1 crosstalk plays in reducing cancer recurrences.…”
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    Combined Targeting of Estrogen Receptor Alpha and XPO1 Prevent Akt Activation, Remodel Metabolic Pathways and Induce Autophagy to Overcome Tamoxifen Resistance
  16. 47356
    “…Among various therapeutic alternatives, we employed stromal vascular fraction (SVF), a heterogeneous cell population, to regenerate damaged knee cartilage. OA patients were classified on the basis of age, gender, body mass index (BMI), and x-ray-derived Kellgren–Lawrence (KL) grade. …”
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    Time- and Kellgren–Lawrence Grade-Dependent Changes in Intra-Articularly Transplanted Stromal Vascular Fraction in Osteoarthritic Patients
  17. 47357
    “…Numerous approaches have been introduced to regenerate artificial dental tissues. However, conventional approaches are limited when producing a construct with three-dimensional patient-specific shapes and compositions of heterogeneous dental tissue. …”
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    Bioprinting of three-dimensional dentin–pulp complex with local differentiation of human dental pulp stem cells
  18. 47358
    “…Interestingly, liver has the unique ability to regenerate and completely recoup from most acute, non-iterative situation. …”
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    Role of Natural Phenolics in Hepatoprotection: A Mechanistic Review and Analysis of Regulatory Network of Associated Genes
  19. 47359
    por Carranza-García, E., Navarro, R. E.
    Publicado 2019
    “…Upon refeeding, the shrunken gonad is regenerated, and animals recover fertility and live out their remaining lifespan. …”
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    Apoptosis contributes to protect germ cells from the oogenic germline starvation response but is not essential for the gonad shrinking or recovery observed during adult reproductive diapause in C. elegans
  20. 47360
    “…A promising therapy seeks to deliver stem cells to the TM to regenerate the tissue and restore its function. However, like many stem cell-based regenerative therapies, preclinical development relies heavily on histology to evaluate outcomes. …”
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    Development of a stem cell tracking platform for ophthalmic applications using ultrasound and photoacoustic imaging
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