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  1. 48621
    “…However, synthesis by biotransformation with immobilized microorganisms is of great interest because it is environmentally friendly and offers high stability and regenerable cofactors. Therefore, we produced 4-hydroxycinnamyl alcohols using immobilized whole cells of engineered Escherichia coli as the biocatalyst. …”
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    Three steps in one pot: biosynthesis of 4-hydroxycinnamyl alcohols using immobilized whole cells of two genetically engineered Escherichia coli strains
  2. 48622
    “…AIMS: Increasing evidence indicates that the ATP‐generating enzyme creatine kinase (CK) is involved in hypertension. CK rapidly regenerates ATP from creatine phosphate and ADP. Recently, it has been shown that beta‐guanidinopropionic acid (GPA), a kidney‐synthesized creatine analogue and competitive CK inhibitor, reduced blood pressure in spontaneously hypertensive rats. …”
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    The acute effect of beta‐guanidinopropionic acid versus creatine or placebo in healthy men (ABC‐Trial): A randomized controlled first‐in‐human trial
  3. 48623
    “…Mesenchymal stem cell studies in animal models of chronic renal failure have uncovered a unique potential of these cells for improving function and regenerating the damaged kidney. CASE PRESENTATION: We report a case of a 62-year-old ethnic Indonesian woman previously diagnosed as having thoracic spinal cord entrapment with paraplegic condition and chronic renal failure on hemodialysis. …”
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    Improvement of renal function after human umbilical cord mesenchymal stem cell treatment on chronic renal failure and thoracic spinal cord entrapment: a case report
  4. 48624
    “…Stem cell therapy can be used to repair and regenerate damaged hearts tissue; nevertheless, the low survival rate of transplanted cells limits their therapeutic efficacy. …”
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    The harsh microenvironment in infarcted heart accelerates transplanted bone marrow mesenchymal stem cells injury: the role of injured cardiomyocytes-derived exosomes
  5. 48625
    “…BACKGROUND: Phosphatase of regenerating liver-3 (PRL-3) has been shown to be highly expressed in various types of cancers and is related to poor prognosis. …”
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    Knockdown of PRL-3 increases mitochondrial superoxide anion production through transcriptional regulation of RAP1
  6. 48626
    “…However, postnatal and adult mouse MGC can be genetically reprogrammed through the expression of the transcription factor (TF) Achaete-scute homolog 1 (ASCL1) into induced neurons (iNs), displaying key hallmarks of photoreceptors, bipolar and amacrine cells, which may contribute to regenerate the damaged retina. Here, we show that the TF neurogenin 2 (NEUROG2) is also sufficient to lineage-reprogram postnatal mouse MGC into iNs. …”
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    Evidence of Müller Glia Conversion Into Retina Ganglion Cells Using Neurogenin2
  7. 48627
    “…Reversion of over-activated to neuroprotective microglia phenotype could regenerate a healthy CNS-supporting microglia environment. …”
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    The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia
  8. 48628
    “…PC allows FM patients to resume their own life and regenerate their own image. Finally, we propose the introduction of the evaluation of the ability to resume daily activities as the target of rehabilitation programs in FM.…”
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    Postural counseling represents a novel option in pain management of fibromyalgia patients
  9. 48629
    “…The most important finding was the observation of presence of small scattered islets in blueberry treated obese mice, which may reflect a potential role of blueberry in regenerating pancreatic β-cells. CONCLUSIONS: Blueberry-supplemented diet can prevent obesity-induced insulin resistance by improving insulin sensitivity and protecting pancreatic β-cells. …”
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    Whole blueberry protects pancreatic beta-cells in diet-induced obese mouse
  10. 48630
    “…Further research is recommended into the therapeutic uses of BMP9 to regenerate traumatized and diseased tissues and for the bioengineering of replacement teeth.…”
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    Dentinogenesis and Tooth-Alveolar Bone Complex Defects in BMP9/GDF2 Knockout Mice
  11. 48631
    por Ojemaye, Mike O., Okoh, Anthony I.
    Publicado 2019
    “…Lastly, Reusability experiments indicate that MNP-Tppy can be regenerated and re-used.…”
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    Multiple nitrogen functionalized magnetic nanoparticles as an efficient adsorbent: synthesis, kinetics, isotherm and thermodynamic studies for the removal of rhodamine B from aqueous solution
  12. 48632
    “…Rare quiescent Sox2(+) cells survived radiation-enhanced p53(R172P) activation and entered a proliferative state, regenerating tumors. Transcriptomes of Sox2(+) cells resembled quiescent Nestin-expressing progenitors in the developing cerebellum, expressing Olig2 known to suppress p53 and p21 expression. …”
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    Sox2(+) cells in Sonic Hedgehog-subtype medulloblastoma resist p53-mediated cell-cycle arrest response and drive therapy-induced recurrence
  13. 48633
    “…BACKGROUND: In most stem cell therapy strategies reported to date, stem cells are introduced to damaged tissue sites to repair and regenerate the original tissue structure and function. …”
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    Phenotypic traits of mesenchymal stem cell sheets fabricated by temperature-responsive cell culture plate: structural characteristics of MSC sheets
  14. 48634
    “…QuantiMus also revealed that the proportion of centrally nucleated, regenerating myofibers that express embryonic myosin heavy chain (eMyHC) or neural cell adhesion molecule (NCAM) were increased in dystrophic mice. …”
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    QuantiMus: A Machine Learning-Based Approach for High Precision Analysis of Skeletal Muscle Morphology
  15. 48635
    “…It induces the proliferation and metabolism of epithelial cells, regenerates skin cells, and validates skin elasticity. …”
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    Optimization of Secreted Recombinant Human Epidermal Growth Factor Production Using Pectate Lyase B from Escherichia Coli BL21(DE3) by Central Composite Design and Its Production in High Cell Density Culture
  16. 48636
    “…The morphology of vegetative organs from regenerated tillers of Shanyou 63 also suggested the superior growth of the upper buds, which was regulated by hormones, in ratoon rice. …”
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    Brassinosteroid signaling may regulate the germination of axillary buds in ratoon rice
  17. 48637
    “…The corresponding increase in endogenous CO(2) production (by PFOR) enabled succinic acid production to be largely maintained as its yield was reduced by only 26%, thus also maintaining the concomitant NADH re-oxidation, essential for regenerating NAD(+) for glycolysis. Acetate yield was slightly reduced as well, while that of lactate was slightly increased. …”
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    Effects of CO(2) limitation on the metabolism of Pseudoclostridium thermosuccinogenes
  18. 48638
    “…Syndecan-4(–/–) mice are unable to regenerate damaged muscle, and display deficient satellite cell activation, proliferation, and differentiation. …”
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    Syndecan-4(–/–) Mice Have Smaller Muscle Fibers, Increased Akt/mTOR/S6K1 and Notch/HES-1 Pathways, and Alterations in Extracellular Matrix Components
  19. 48639
    “…Being proliferative and located near neurons, astrocytes are considered ideal cell sources for regenerating neurons. METHODS: We selected and tested different combinations of the small molecules for inducing the conversion of human and mouse astrocytes into neurons. …”
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    Efficient and rapid conversion of human astrocytes and ALS mouse model spinal cord astrocytes into motor neuron-like cells by defined small molecules
  20. 48640
    por Kim, Hyeran, Choi, Jisun, Won, Kang-Hee
    Publicado 2020
    “…CONCLUSIONS: Pepper protoplast-based CRISPR guide-RNA selection is a robust method to check the efficacy of designed CRISPR tools and is a prerequisite for regenerating edited plants, which is a critical time-limiting procedure. …”
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    A stable DNA-free screening system for CRISPR/RNPs-mediated gene editing in hot and sweet cultivars of Capsicum annuum
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