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439461por Hirst, Jane Elizabeth, Votruba, Nicole, Billot, Laurent, Arora, Varun, Rajan, Eldho, Thout, Sudhir Raj, Peiris, David, Patel, Anushka, Norton, Robyn, Mullins, Edward, Sharma, Ankita, Kennedy, Stephen, Jha, Vivekanand, Praveen, Devarsetty“…Thirty PHCs in Telangana and Haryana will be randomised 1:1 using a matched-pair design accounting for cluster size and distance from the regional centre. The intervention comprises (i) an education programme for community health workers and PHC doctors; (ii) the SMARThealth Pregnancy app for health workers to support community-based screening, referral and follow-up of high-risk cases; (iii) a dashboard for PHC doctors to monitor high-risk women in the community; (iv) supply chain monitoring for consumables and medications and (v) stakeholder engagement to co-develop implementation and sustainability pathways. …”
Publicado 2023
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439462por Kakar, Ellaha, Ottens, Thomas, Stads, Susanne, Wesselius, Sanne, Gommers, Diederik A. M. P. J., Jeekel, Johannes, van der Jagt, Mathieu“…METHODS: A multicenter randomized clinical trial was conducted between August 2020 and December 2021 in ICU’s at an academic medical centre and two regional hospitals. Adult critically ill patients were eligible when hemodynamically stable and able to communicate (Richmond agitation-sedation scale (RASS) of at least − 2). …”
Publicado 2023
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439463por Wu, Ruohao, Li, Xiaohui, Chen, Zhishan, Shao, Qiong, Zhang, Xiao, Tang, Wenting, Hu, Bo“…CONCLUSIONS: We developed a simple-to-use nomogram based on common laboratory indicators to identify the subgroup of ultra high-risk NB before treatment, providing these children even from developing countries or regions access to intensified multimodal treatments earlier and thus improving their long-term outcome. …”
Publicado 2023
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439464por Shuyuan, Yin, Meimei, Wang, Fenghua, Li, Huishan, Zhao, Min, Chu, Hongchu, Bao, Xuemei, Liu“…Further investigation showed that ECM-related genes were downregulated in the CTX and BUS treatment group and partially rescued in hUMSCs injection group but not in the PBS group. qRT-PCR and IHC verified the results: collagen IV and laminin gamma 3 were both expressed around follicle regions in normal ovaries, chemotherapy treatment disrupted their expression, and hUMSCs transplantation rescued their localization and expression to some extent. …”
Publicado 2023
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439465“…METHODS: This study sampled 1,528 community-dwelling adults on medications (young adults:766, older adults: 762) from a cross-sectional population health survey conducted in the northern and central regions of Singapore in 2018/2019. Self-reported medication non-adherence and its reasons were collected using a modified questionnaire and compared between the two groups. …”
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439466por Mare, Kusse Urmale, Sabo, Kebede Gemeda, Mohammed, Ahmed Adem, Leyto, Simeon Meskele, Mulaw, Getahun Fentaw, Tebeje, Tsion Mulat, Aychiluhm, Setognal Birara, Ebrahim, Oumer Abdulkadir, Wuneh, Abel Gebre, Seifu, Beminate Lemma“…Thus, interventions designed at enhancing optimal birth spacing should pay particular attention to young and socioeconomically disadvantaged women and those residing in rural regions. Strengthening community health programs and improving accessibility and availabilities of fertility control methods that ultimately impacts optimal reproductive behaviors is crucial to address contraceptive utilization and unmet need.…”
Publicado 2023
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439467por Zhang, Shun-Xian, Wang, Ji-Chun, Li, Zhong-Wei, Zheng, Jin-Xin, Zhou, Wen-Ting, Yang, Guo-Bing, Yu, Ying-Fang, Wu, Xiu-Ping, Lv, Shan, Liu, Qin, Chen, Mu-Xin, Lu, Yan, Dou, Zhi-Hui, Zhang, Da-Wei, Lv, Wen-Wen, Wang, Lei, Lu, Zhen-Hui, Yang, Ming, Zheng, Pei-Yong, Chen, Yue-Lai, Tian, Li-Guang, Zhou, Xiao-Nong“…It is crucial to consider the simultaneous surveillance of HIV VL and CD4(+) T cell counts in PLWH in the regions with high level of socioeconomic development. …”
Publicado 2023
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439468por Sang, Linchao, Ding, Luobin, Hao, Kangning, Zhang, Ce, Shen, Xiaoyu, Sun, Hui, Fu, Dehao, Qi, Xiangbei“…Differences in the lncRNA expression profiles between the thrombotic samples of the PMMA group and ES-PMMA group were assessed by base-to-base alignment in the intergenic regions of genomes. The lncRNA-miRNA-mRNA competitive endogenous RNA (ceRNA) network was established in light of ceRNA theory. …”
Publicado 2023
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439469por Gu, Si-Yu, Chen, Fu-Min, Zhang, Chen-Sheng, Zhou, Yi-Bin, Li, Tian-Yun, Qiang, Ne, Zhang, Xiao-Xi, Liu, Jing-Shu, Wang, Shu-Xun, Yang, Xue-Chen, Guo, Xiao-Kui, Hu, Qin-Qin, Deng, Xiao-Bei, Han, Le-Fei“…The highest average score of first-level indicators was Nutrition (69.8) and the lowest was Government Support and Response (31.3). There was regional heterogeneity of GOHI-FS scores. Higher median scores with interquartile range (IQR) were shown in North America (median: 76.1, IQR: 75.5–76.7), followed by Europe and Central Asia (median: 66.9, IQR: 60.1–74.3), East Asia and the Pacific (median: 60.6, IQR: 55.5–68.7), Latin America and the Caribbean (median: 60.2, IQR: 57.8–65.0), Middle East and North Africa (median: 56.6, IQR: 52.0–62.8), South Asia (median: 51.1, IQR: 46.7–53.8), and sub-Saharan Africa (median: 41.4, IQR: 37.2–46.5). …”
Publicado 2023
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439470“…Despite lower odds, women of the age groups 20–24 (AOR = 2.33; 95% CI = 2.054–2.637), cohabitaing (AOR = 1.07; 95% CI = 0.981–1.173), secondary or higher education (AOR = 1.55; 95% CI = 1.385–1.736), Central (AOR = 1.48; 95% CI = 1.296–1.682) and Eastern (AOR = 1.48; 95% CI = 1.289–1.695) regions significantly predicted modern contraceptive use. …”
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439471por Seyed Hajizadeh, Hanifeh, Azizi, Sahar, Aghaee, Ahmad, Karakus, Sinem, Kaya, Ozkan“…BACKGROUND: Rosa damascena is extensively cultivated in various regions of Iran due to its aesthetic attributes, medicinal qualities, and essential oil production. …”
Publicado 2023
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439472por Lin, Feng, Yang, Kang, Lin, Xin, Jin, Ming, Chen, Long, Zheng, Fu-ze, Qiu, Liang-liang, Ye, Zhi-xian, Chen, Hai-zhu, Lin, Min-ting, Wang, Ning, Wang, Zhi-qiang“…The frequency of LGMD subtypes varies among regions in China and ethnic populations worldwide. …”
Publicado 2023
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439473“…The mean standardized uptake value (SUV(mean)) and maximum standardized uptake value (SUV(max)) of brain relative regional metabolism (BRRM) were quantified in the case and control groups according to the anatomical automatic labeling (AAL) partition. …”
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439474por Chen, Zhuo, Hua, Sha, Gao, Juan, Chen, Yanjia, Gong, Yiwen, Shen, Yiwen, Tang, Xin, Emu, Yixin, Jin, Wei, Hu, Chenxi“…The VI sub-network well identified the location of banding and flow artifacts in the original movie and significantly correlated with the change of signal intensities in these regions. Changes of imaging parameters or the scanner did not cause a significant change of overall image quality relative to the baseline dataset, suggesting a good generalizability. …”
Publicado 2023
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439475por Van Kerkhove, Maria D., Vandemaele, Katelijn A. H., Shinde, Vivek, Jaramillo-Gutierrez, Giovanna, Koukounari, Artemis, Donnelly, Christl A., Carlino, Luis O., Owen, Rhonda, Paterson, Beverly, Pelletier, Louise, Vachon, Julie, Gonzalez, Claudia, Hongjie, Yu, Zijian, Feng, Chuang, Shuk Kwan, Au, Albert, Buda, Silke, Krause, Gerard, Haas, Walter, Bonmarin, Isabelle, Taniguichi, Kiyosu, Nakajima, Kensuke, Shobayashi, Tokuaki, Takayama, Yoshihiro, Sunagawa, Tomi, Heraud, Jean Michel, Orelle, Arnaud, Palacios, Ethel, van der Sande, Marianne A. B., Wielders, C. C. H. Lieke, Hunt, Darren, Cutter, Jeffrey, Lee, Vernon J., Thomas, Juno, Santa-Olalla, Patricia, Sierra-Moros, Maria J., Hanshaoworakul, Wanna, Ungchusak, Kumnuan, Pebody, Richard, Jain, Seema, Mounts, Anthony W.“…METHODS AND FINDINGS: Data were collected on approximately 70,000 laboratory-confirmed hospitalized H1N1pdm patients, 9,700 patients admitted to intensive care units (ICUs), and 2,500 deaths reported between 1 April 2009 and 1 January 2010 from 19 countries or administrative regions—Argentina, Australia, Canada, Chile, China, France, Germany, Hong Kong SAR, Japan, Madagascar, Mexico, the Netherlands, New Zealand, Singapore, South Africa, Spain, Thailand, the United States, and the United Kingdom—to characterize and compare the distribution of risk factors among H1N1pdm patients at three levels of severity: hospitalizations, ICU admissions, and deaths. …”
Publicado 2011
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439476por Archambault, Patrick M, Turgeon, Alexis F, Witteman, Holly O, Lauzier, François, Moore, Lynne, Lamontagne, François, Horsley, Tanya, Gagnon, Marie-Pierre, Droit, Arnaud, Weiss, Matthew, Tremblay, Sébastien, Lachaine, Jean, Le Sage, Natalie, Émond, Marcel, Berthelot, Simon, Plaisance, Ariane, Lapointe, Jean, Razek, Tarek, van de Belt, Tom H, Brand, Kevin, Bérubé, Mélanie, Clément, Julien, Grajales III, Francisco Jose, Eysenbach, Gunther, Kuziemsky, Craig, Friedman, Debbie, Lang, Eddy, Muscedere, John, Rizoli, Sandro, Roberts, Derek J, Scales, Damon C, Sinuff, Tasnim, Stelfox, Henry T, Gagnon, Isabelle, Chabot, Christian, Grenier, Richard, Légaré, France“…BACKGROUND: Trauma is the most common cause of mortality among people between the ages of 1 and 45 years, costing Canadians 19.8 billion dollars a year (2004 data), yet half of all patients with major traumatic injuries do not receive evidence-based care, and significant regional variation in the quality of care across Canada exists. …”
Publicado 2015
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439477por Panagiotakaki, Eleni, De Grandis, Elisa, Stagnaro, Michela, Heinzen, Erin L., Fons, Carmen, Sisodiya, Sanjay, de Vries, Boukje, Goubau, Christophe, Weckhuysen, Sarah, Kemlink, David, Scheffer, Ingrid, Lesca, Gaëtan, Rabilloud, Muriel, Klich, Amna, Ramirez-Camacho, Alia, Ulate-Campos, Adriana, Campistol, Jaume, Giannotta, Melania, Moutard, Marie-Laure, Doummar, Diane, Hubsch-Bonneaud, Cecile, Jaffer, Fatima, Cross, Helen, Gurrieri, Fiorella, Tiziano, Danilo, Nevsimalova, Sona, Nicole, Sophie, Neville, Brian, van den Maagdenberg, Arn M. J. M., Mikati, Mohamad, Goldstein, David B., Vavassori, Rosaria, Arzimanoglou, Alexis“…In general, mutations were found to cluster into five different regions. The most frequent mutations included: p.Asp801Asn (43 %; 57/132), p.Glu815Lys (16 %; 22/132), and p.Gly947Arg (11 %; 15/132). …”
Publicado 2015
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439478por Tagge, Chad A, Fisher, Andrew M, Minaeva, Olga V, Gaudreau-Balderrama, Amanda, Moncaster, Juliet A, Zhang, Xiao-Lei, Wojnarowicz, Mark W, Casey, Noel, Lu, Haiyan, Kokiko-Cochran, Olga N, Saman, Sudad, Ericsson, Maria, Onos, Kristen D, Veksler, Ronel, Senatorov, Vladimir V, Kondo, Asami, Zhou, Xiao Z, Miry, Omid, Vose, Linnea R, Gopaul, Katisha R, Upreti, Chirag, Nowinski, Christopher J, Cantu, Robert C, Alvarez, Victor E, Hildebrandt, Audrey M, Franz, Erich S, Konrad, Janusz, Hamilton, James A, Hua, Ning, Tripodis, Yorghos, Anderson, Andrew T, Howell, Gareth R, Kaufer, Daniela, Hall, Garth F, Lu, Kun P, Ransohoff, Richard M, Cleveland, Robin O, Kowall, Neil W, Stein, Thor D, Lamb, Bruce T, Huber, Bertrand R, Moss, William C, Friedman, Alon, Stanton, Patric K, McKee, Ann C, Goldstein, Lee E“…These pathologies were also accompanied by early, persistent, and bilateral impairment in axonal conduction velocity in the hippocampus and defective long-term potentiation of synaptic neurotransmission in the medial prefrontal cortex, brain regions distant from acute brain injury. Surprisingly, acute neurobehavioural deficits at the time of injury did not correlate with blood–brain barrier disruption, microgliosis, neuroinflammation, phosphorylated tauopathy, or electrophysiological dysfunction. …”
Publicado 2018
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439479por Deschasaux, Mélanie, Huybrechts, Inge, Murphy, Neil, Julia, Chantal, Hercberg, Serge, Srour, Bernard, Kesse-Guyot, Emmanuelle, Latino-Martel, Paule, Biessy, Carine, Casagrande, Corinne, Jenab, Mazda, Ward, Heather, Weiderpass, Elisabete, Dahm, Christina C., Overvad, Kim, Kyrø, Cecilie, Olsen, Anja, Affret, Aurélie, Boutron-Ruault, Marie-Christine, Mahamat-Saleh, Yahya, Kaaks, Rudolf, Kühn, Tilman, Boeing, Heiner, Schwingshackl, Lukas, Bamia, Christina, Peppa, Eleni, Trichopoulou, Antonia, Masala, Giovanna, Krogh, Vittorio, Panico, Salvatore, Tumino, Rosario, Sacerdote, Carlotta, Bueno-de-Mesquita, Bas, Peeters, Petra H., Hjartåker, Anette, Rylander, Charlotta, Skeie, Guri, Ramón Quirós, J., Jakszyn, Paula, Salamanca-Fernández, Elena, Huerta, José María, Ardanaz, Eva, Amiano, Pilar, Ericson, Ulrika, Sonestedt, Emily, Huseinovic, Ena, Johansson, Ingegerd, Khaw, Kay-Tee, Wareham, Nick, Bradbury, Kathryn E., Perez-Cornago, Aurora, Tsilidis, Konstantinos K., Ferrari, Pietro, Riboli, Elio, Gunter, Marc J., Touvier, Mathilde“…How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations. …”
Publicado 2018
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439480por Pinto, A., Adams, S., Ahring, K., Allen, H., Almeida, M.F., Garcia-Arenas, D., Arslan, N., Assoun, M., Atik Altınok, Y., Barrio-Carreras, D., Belanger Quintana, A., Bernabei, S.M., Bontemps, C., Boyle, F., Bruni, G., Bueno-Delgado, M., Caine, G., Carvalho, R., Chrobot, A., Chyż, K., Cochrane, B., Correia, C., Corthouts, K., Daly, A., De Leo, S., Desloovere, A., De Meyer, A., De Theux, A., Didycz, B., Dijsselhof, M.E., Dokoupil, K., Drabik, J., Dunlop, C., Eberle-Pelloth, W., Eftring, K., Ekengren, J., Errekalde, I., Evans, S., Foucart, A., Fokkema, L., François, L., French, M., Forssell, E., Gingell, C., Gonçalves, C., Gökmen Özel, H., Grimsley, A., Gugelmo, G., Gyüre, E., Heller, C., Hensler, R., Jardim, I., Joost, C., Jörg-Streller, M., Jouault, C., Jung, A., Kanthe, M., Koç, N., Kok, I.L., Kozanoğlu, T., Kumru, B., Lang, F., Lang, K., Liegeois, I., Liguori, A., Lilje, R., Ļubina, O., Manta-Vogli, P., Mayr, D., Meneses, C., Newby, C., Meyer, U., Mexia, S., Nicol, C., Och, U., Olivas, S.M., Pedrón-Giner, C., Pereira, R., Plutowska-Hoffmann, K., Purves, J., Re Dionigi, A., Reinson, K., Robert, M., Robertson, L., Rocha, J.C., Rohde, C., Rosenbaum-Fabian, S., Rossi, A., Ruiz, M., Saligova, J., Gutiérrez-Sánchez, A., Schlune, A., Schulpis, K., Serrano-Nieto, J., Skarpalezou, A., Skeath, R., Slabbert, A., Straczek, K., Giżewska, M., Terry, A., Thom, R., Tooke, A., Tuokkola, J., van Dam, E., van den Hurk, T.A.M., van der Ploeg, E.M.C., Vande Kerckhove, K., Van Driessche, M., van Wegberg, A.M.J., van Wyk, K., Vasconcelos, C., Velez García, V., Wildgoose, J., Winkler, T., Żółkowska, J., Zuvadelli, J., MacDonald, A.“…Centres were grouped into geographical regions for analysis. RESULTS: Weaning started at 17–26 weeks in 85% (n = 81/95) of centres, >26 weeks in 12% (n = 11/95) and < 17 weeks in 3% (n = 3/95). …”
Publicado 2018
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