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  1. 439761
    “…METHODS: We harmonised and pooled individual-level data from 15 observational studies done across five countries and regions (Australia, Scandinavia, the USA, Japan, and the UK) between 1946 and 2013. …”
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    Age at natural menopause and risk of incident cardiovascular disease: a pooled analysis of individual patient data
  2. 439762
    “…OAS uses ATP to generate 2′,5′-linked oligoadenylates (2-5A). 2-5A binds to and activates the ubiquitous cellular endoribonuclease RNase L causing cleavages of single stranded regions of both viral and cellular RNA thus inhibiting viral replication. …”
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    O030 Evasion of the OAS-RNase L pathway by murine coronavirus ns2 protein is required for viral replication and hepatitis
  3. 439763
    “…They should also be trained to prevent, detect and treat early warning symptoms of post-traumatic stress disorder, because their prevalence was high in the regions of China most affected by the pandemic. DISCUSSION: French mental healthcare is now in a great and urgent need for reorganization and must also prepare in the coming days and weeks to face an epidemic of emotional disorders due to the containment of the general population.…”
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    Assurer les soins aux patients souffrant de troubles psychiques en France pendant l’épidémie à SARS-CoV-2
  4. 439764
    “…Peu de données sont disponibles dans les pays tropicaux malgré une augmentation de la prévalence de l’asthme dans ces régions ces dernières années. MÉTHODES: Dans cette étude observationnelle réalisée sur l’année 2015, l’épidémiologie virale de patients adultes hospitalisés pour exacerbation d’asthme a été comparée entre la ville de Saint Pierre à la Réunion (climat tropical) et de Tours (climat tempéré). …”
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    Exacerbation d’asthme et virus : quelles différences en fonction des zones climatiques ?
  5. 439765
    “…Differentially methylated positions (p value cutoff < 1 × 10(−4) and ten or more DMPs per gene) and regions (inclusion threshold 0.2, p value cutoff < 1 × 10(−2) and more than 2 DMRs per gene) were identified using dmpfinder and Bumphunter (minfi), respectively. …”
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    Adipose stem cells from patients with Crohn’s disease show a distinctive DNA methylation pattern
  6. 439766
    “…Viral contigs were connected using Sanger sequencing to obtain the full-length genomes, with the terminal regions determined by rapid amplification of cDNA ends. …”
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    Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
  7. 439767
    “…INTERPRETATION: Our findings are consistent with person-to-person transmission of this novel coronavirus in hospital and family settings, and the reports of infected travellers in other geographical regions. FUNDING: The Shaw Foundation Hong Kong, Michael Seak-Kan Tong, Respiratory Viral Research Foundation Limited, Hui Ming, Hui Hoy and Chow Sin Lan Charity Fund Limited, Marina Man-Wai Lee, the Hong Kong Hainan Commercial Association South China Microbiology Research Fund, Sanming Project of Medicine (Shenzhen), and High Level-Hospital Program (Guangdong Health Commission).…”
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    A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster
  8. 439768
    “…They should also be trained to prevent, detect and treat early warning symptoms of post-traumatic stress disorder, because their prevalence was high in the regions of China most affected by the pandemic. DISCUSSION: French mental healthcare is now facing a great and urgent need for reorganization and must also prepare in the coming days and weeks to face an epidemic of emotional disorders due to the confinement of the general population.…”
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    Ensuring mental health care during the SARS-CoV-2 epidemic in France: A narrative review
  9. 439769
    “…These data had been collected from 31 provinces and regions in China and included geographical, seasonal, and patient demographic information. …”
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    Resurgence of scarlet fever in China: a 13-year population-based surveillance study
  10. 439770
    “…The Youbike started demonstration operation, initially setting up 11 station points and 500 bicycles in the peripheral regions of Xinyi District on March 11th, 2009, and now there are 400 station points in all districts. 4. …”
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    The implementation results of safe bicycle transport in Taipei City
  11. 439771
    “…Transactive response DNA-binding protein (TDP-43) has been discovered to accumulate in limbic brain regions of a portion of late-onset Alzheimer’s disease (AD) patients, in addition to amyloid-β and τ protein. …”
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    Distinct molecular patterns of TDP-43 pathology in Alzheimer’s disease: relationship with clinical phenotypes
  12. 439772
    “…STUDY DESIGN, SIZE, DURATION: A prospective multicenter study with national coverage including 610 women with BC counseled between 1 January 1995 and 30 June 2017 at six Swedish FP regional programs. PARTICIPANTS/MATERIALS, SETTING, METHODS: After counseling, 401 women elected to undergo COS. …”
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    Efficacy and safety of controlled ovarian stimulation using GnRH antagonist protocols for emergency fertility preservation in young women with breast cancer—a prospective nationwide Swedish multicenter study
  13. 439773
    “…TAC were different between regions within central Illinois (RR 1.39; 95% CI 1.08-1.80; p 0.002). …”
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    MON-083 Childhood Diabetic Ketoacidosis (DKA) in New-Onset and Established Patients in Central Illinois: Contributing Factors and Risk Stratification
  14. 439774
    “…Here, we identify that CIMP-high ACC exhibit high expression of EZH2/H3K27me3, but paradoxically bear DNA hypermethylation in annotated PRC2 target regions. To determine if DNA methylation of PRC2 targets disrupts or is controlled by EZH2, we characterized EZH2’s role in CIMP-high ACC cell line NCI-H295R at baseline and in response to EZH2 inhibition (EZH2i). …”
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    SAT-LB34 Repressive Epigenetic Programs Reinforce Steroidogenic Differentiation and Wnt/β-Catenin Signaling in Aggressive Adrenocortical Carcinoma
  15. 439775
    “…These include lower-level processes (e.g. emotion recognition), thought to be subserved by a frontoparietal mirroring network, and higher-level mentalizing processes (e.g. theory of mind), involving cortical midline and lateral temporal brain regions. Across both disorders, impairments in social cognition persist over time, drive disability, and predict functional outcome. …”
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    M49. BEHAVIOURAL SOCIAL COGNITION IN SCHIZOPHRENIA SPECTRUM DISORDERS IN COMPARISON TO AUTISM SPECTRUM DISORDER: A SYSTEMATIC REVIEW AND META-ANALYSIS
  16. 439776
    “…RESULTS: Individual participant data from seven studies were included, amounting to 99 patients with first-episode psychosis or schizophrenia and 109 healthy control subjects. In all regions investigated, BF showed moderate to strong support (BF > 5) for lower VT in patients as compared to no difference, and strong support (BF > 10) for lower VT compared to higher VT in patients. …”
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    T7. UPDATED INDIVIDUAL PARTICIPANT DATA META-ANALYSIS CONFIRMS LOWER LEVELS OF THE GLIAL MARKER TSPO IN PSYCHOSIS PATIENTS
  17. 439777
    “…In addition, beta receptors have unique localization in cortical regions (i.e., hippocampus), and improve social behaviors and cognition in some animal models, which has led to interests in these compounds for testing in schizophrenia. …”
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    S32. ARE SELECTIVE ESTROGEN RECEPTOR BETA AGONISTS POTENTIAL THERAPEUTICS FOR SCHIZOPHRENIA?
  18. 439778
    “…Structural T1 images underwent visual quality control, were realigned and parcellated into 176 gray and white matter regions using FreeSurfer software. Preliminary analyses were conducted comparing 1) MMP-9 levels between groups and 2) relating MMP-9 levels to ChP volume utilizing regression analyses. …”
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    S168. THE ASSOCIATION BETWEEN MMP-9 AND CHOROID PLEXUS VOLUME IN SCHIZOPHRENIA
  19. 439779
    “…Out of these, 14 were located in gene-coding regions. Interestingly, 9 of these genes are implicated in neuronal development/function or metabolite transport/transformation. …”
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    T81. MULTIPLE DRUG USE IN SCHIZOPHRENIA - THE ROLE OF EARLY ENVIRONMENTAL RISK ACCUMULATION AND GENETIC PREDISPOSITION
  20. 439780
    “…Second, in considering demographic and clinical correlates of medication adherence in patients with recurrent schizophrenia, our MARS study broadly represents China with 17 of 27 provinces/municipalities reporting data from multiple geographic regions, with the participation of hundreds of psychiatrists across China. …”
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    T217. MEDICATION ADHERENCE AND ITS CORRELATES AMONG PATIENTS WITH RECURRENT SCHIZOPHRENIA: A LARGE-SCALE STUDY IN CHINA
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