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  1. 440021
    “…Multivariate analysis demonstrated that adults (hazard ratio [HR] = 7.4), Asian or Pacific Islander (HR = 0.5), male (HR = 0.8), poorly differentiated histology (HR = 3.8), undifferentiated histology (HR = 4.5), regional spread (HR = 2.1), and distant spread (HR = 3.2) were associated with increased mortality (p < 0.05). …”
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  2. 440022
    “…Furthermore, this study was conducted among an African population and Africa has been shown to be generally less severely hit by the COVID‐19 pandemic compared to other regions outside the continent. This has been postulated to be due, among other factors, to inherent protective mechanisms in Africans due to early and repeated exposure to parasitic and other organisms resulting in a robust innate immunity. …”
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  3. 440023
    “…For rectal cancer, the rate of “surgery plus chemotherapy and/or radiotherapy” was higher for people with regional spread of disease (versus localised, SHR=5.2, 95%CI:3.6-7.7) and lower for people with poorer physical functioning (SHR=0.5, 95%CI:0.3-0.8) or no private health insurance (SHR=0.7, 95%CI:0.5-0.9). …”
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  4. 440024
  5. 440025
    “…METHODS: For this analysis, we used the GLOBOCAN 2020 database to estimate the age-specific and age-standardised incidence and mortality rates of cervical cancer per 100 000 women-years for 185 countries or territories aggregated across the 20 UN-defined world regions, and by four-tier levels of the Human Development Index (HDI). …”
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  6. 440026
  7. 440027
    “…The lower figure of nine macrospecies is based primarily on seeking small but reliable discontinuities in DNA ‘barcode’ regions, an approach subsequently reinforced and finessed via high-throughput sequencing studies. …”
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  8. 440028
    “…DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort of 492 consecutive patients with metastatic melanoma treated with ICB at 2 tertiary and 4 regional cancer centers in Alberta, Canada, from August 1, 2013, to May 31, 2020, was observed. …”
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  9. 440029
    “…Second, results were generalized to three target populations who would benefit from MOUD: Housed adults identifying the need for OUD treatment, as characterized by the National Survey on Drug Use and Health (NSDUH); adults entering OUD treatment, as characterized by Treatment Episodes Dataset (TEDS); and adults living in rural regions of the U.S. with high rates of injection drug use, as characterized by the Rural Opioids Initiative (ROI). …”
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  10. 440030
    “…However, the effect of Intermittent Prophylactic Treatment in Pregnancy (IPTp) and placental malaria on the extent of in-utero antibody transfer in malaria endemic regions like Uganda remain unknown. The aim of this study was thus to establish the effect of IPTp on in-utero transfer of malaria specific IgG to the fetus and the associated immune protection against malaria in the first birth year of children born to mothers who had P. falciparum infection during pregnancy in Uganda. …”
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  11. 440031
  12. 440032
    “…We pooled proportion estimates via random-effects meta-analyses and explored subgroup differences by gender, occupational group, training stage, WHO regions/continents, and study end-year. We assessed risk of bias (Newcastle–Ottawa scale for observational studies, RοB2 for randomized controlled trials [RCT]) and rated evidence certainty using GRADE. …”
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  13. 440033
    “…GR ablation from Sox9-expressing cochlear supporting cells resulted in a permanent threshold shift in mid-basal cochlear frequency regions after mild noise exposure that produced only a temporary threshold shift in both control (no tamoxifen) f/fGR:Sox9iCre(+) and heterozygous f/+GR:Sox9iCre(+) tamoxifen-treated mice. …”
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  14. 440034
    “…Low dietary CP content induced hepatocyte disorganization and moderate degeneration, along with vacuolated hepatic cells, excessive connective tissue, and lymphocytic infiltration. The cortical regions of the kidney exhibited obvious alterations in the Gr3 and Gr4 groups and large interstitial spaces were found between tubules. …”
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  15. 440035
    “…CONCLUSION: DNA amplification of Holstein cattle for the polymorphic regions of PRL and NOS2 using the PCR-RFLP method revealed a possible connection between the distribution of relative allele frequencies of bPRL and bNOS2 and resistance to viral and bacterial infections. …”
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  16. 440036
    “…The adjusted odds of CS deliveries were significantly higher among women who were highly educated (odds ratio [OR] 7.30, 95% CI 7.02-7.60; P<.001), had 4 or more ANC visits (OR 2.28, 95% CI 2.15-2.42; P<.001), belonging to the high-wealth quintile (OR 7.87, 95% CI 7.57-8.18; P<.001), and from urban regions. Increasing educational level of the head of the household (OR 3.05, 95% CI 2.94-3.16; P<.001) was also found to be a significant determinant of CS deliveries. …”
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  17. 440037
    “…The study population was only representative of women in the UK and results may not be generalizable to other regions. PCOS diagnoses were based on codes entered into the system by primary care providers, and no information was available regarding the criteria used for diagnosis, although symptoms used to diagnose PCOS have not changed over time. …”
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  18. 440038
    “…CONCLUSIONS AND RELEVANCE: This cohort study suggests that the forceps major of the corpus callosum and the superior parietal lobule were vulnerable regions in preterm infants. Preterm birth and suboptimal postnatal growth could have negative associations with brain maturation, including altered microstructure and functional connectivity. …”
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  19. 440039
    “…The study revealed that the most used sources of online COVID-19 information for Italian caregivers were social media platforms and mobile apps, while in the case of the Swedish caregivers, online portals and apps published by state, regional, or municipal authorities were the most used sources. …”
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  20. 440040
    por Kwak, Soo Heon, Hernandez-Cancela, Ryan B., DiCorpo, Daniel A, Condon, David E., Merino, Jordi, Wu, Peitao, Brody, Jennifer A, Yao, Jie, Guo, Xiuqing, Ahmadizar, Fariba, Meyer, Mariah, Sincan, Murat, Mercader, Josep M., Lee, Sujin, Haessler, Jeffrey, Vy, Ha My T., Lin, Zhaotong, Armstrong, Nicole D., Gu, Shaopeng, Tsao, Noah L., Lange, Leslie A., Wang, Ningyuan, Wiggins, Kerri L., Trompet, Stella, Liu, Simin, Loos, Ruth J.F., Judy, Renae, Schroeder, Philip H., Hasbani, Natalie R., Bos, Maxime M., Morrison, Alanna C., Jackson, Rebecca D., Reiner, Alexander P., Manson, JoAnn E., Chaudhary, Ninad S., Carmichael, Lynn K., Chen, Yii-Der Ida, Taylor, Kent D., Ghanbari, Mohsen, van Meurs, Joyce, Pitsillides, Achilleas N, Psaty, Bruce M., Noordam, Raymond, Do, Ron, Park, Kyong Soo, Jukema, J Wouter, Kavousi, Maryam, Correa, Adolfo, Rich, Stephen S., Damrauer, Scott M., Hajek, Catherine, Cho, Nam H., Irvin, Marguerite R., Pankow, James S., Nadkarni, Girish N., Sladek, Robert, Goodarzi, Mark O., Florez, Jose C., Chasman, Daniel I., Heckbert, Susan R., Kooperberg, Charles, Dupuis, Josée, Malhotra, Rajeev, de Vries, Paul S., Liu, Ching-Ti, Rotter, Jerome I., Meigs, James B.
    Publicado 2023
    “…CONCLUSIONS: The data point to novel and known genomic regions associated with incident CVD among individuals with T2D.…”
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