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601por Chabaud, V, De Groot, J, Hyams, Bernard David, Papadopoulou, T D, Weilhammer, Peter, Niczyporuk, B B, Rybicki, K, Turala, Michal, Becker, H, Blanar, G J, Blum, Walter, Cerrada-Canales, M, Dietl, H, Gallivan, J, Gottschalk, B, Lorenz, E, Lütjens, G, Lutz, Gerhard, Männer, W, Notz, D, Richter, R H, Stierlin, U, Stringfellow, B C, Wagner, F“…The results confirm the existence of an A/sub 1/ resonance in the region 1.2-1.3 GeV. (20 refs).…”
Publicado 1980
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602“…In one of them, all heavy neutrinos decay shortly before big bang nucleosynthesis. In the other two regions, one of the heavy neutrinos either decays between BBN and the CMB decoupling or is quasi-stable. …”
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603por Liu, Mingtao, Gan, Hui, Liang, Zhiman, Liu, Li, Liu, Qiwen, Mai, Yiyin, Chen, Huihuang, Lei, Baoying, Yu, Shangwei, Chen, Huihui, Zheng, Peiyan, Sun, Baoqing“…We intend to review our current knowledge about antibodies targeting various regions (i.e., RBD regions, non-RBD regions, host cell targets, and cross-neutralizing antibodies), as well as the current scientific evidence for neutralizing-antibody-based treatments based on convalescent plasma therapy, intravenous immunoglobulin, monoclonal antibodies, and recombinant drugs. …”
Publicado 2023
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604A multi-omic resource of wheat seed tissues for nutrient deposition and improvement for human healthpor Zhi, Jingjing, Zeng, Jian, Wang, Yaqiong, Zhao, Hongyan, Wang, Guoli, Guo, Jing, Wang, Yuesheng, Chen, Mingjie, Yang, Guangxiao, He, Guangyuan, Chen, Xiaoyuan, Chang, Junli, Li, Yin“…However, the dynamic changes in nutritional profiles of different wheat seed regions (i.e., the embryo, endosperm and outer layers) during developmental stages and the molecular regulation have not been well studied. …”
Publicado 2023
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605“…Antibiotic resistance is becoming a common problem in medicine, food, and industry, with multidrug-resistant bacterial strains occurring in all regions. One of the possible future solutions is the use of bacteriophages. …”
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606por Spronk, Steven A., Glick, Zachary L., Metcalf, Derek P., Sherrill, C. David, Cheney, Daniel L.“…Molecular fragments representing commonly found substructures in proteins and small-molecule ligands were paired into >9000 unique dimers, assembled into numerous configurations using an approach designed to adequately cover the breadth of the dimers’ potential energy surfaces while enhancing sampling in favorable regions. ~1.5 million configurations of these dimers were randomly generated, and a structurally diverse subset of these were minimized to obtain an additional ~80 thousand local and global minima. …”
Publicado 2023
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607por Barrera-Téllez, Francisco J., Prieto-Martínez, Fernando D., Hernández-Campos, Alicia, Martínez-Mayorga, Karina, Castillo-Bocanegra, Rafael“…Human leishmaniasis is a neglected tropical disease which affects nearly 1.5 million people every year, with Mexico being an important endemic region. One of the major defense mechanisms of these parasites is based in the polyamine metabolic pathway, as it provides the necessary compounds for its survival. …”
Publicado 2023
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608“…The current collection comprises 13 873 hypervariable region I (HVRI) sequences and 4940 hypervariable region II (HVRII) sequences. …”
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609“…In support of this hypothesis, we show that the promoter regions (1 kb upstream of the transcription start site TSS) of genes are significantly enriched in quadruplex motifs relative to the rest of the genome, with >40% of human gene promoters containing one or more quadruplex motif. …”
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610Publicado 1992“…Complementary determining region 1 (CDR1) mutation in CLLs is particularly prevalent, and interchanges in CDRs often lead to acquisition of charge. …”
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611por Maillard, Pierre V, Reynard, Séverine, Serhan, Fatima, Turelli, Priscilla, Trono, Didier“…Our results reveal that changes at tyrosine(336) of human TRIM5α, within the variable region 1 of its C-terminal PRYSPRY domain, can expand its activity to B-MLV and to the NB-tropic Moloney MLV. …”
Publicado 2007
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612“…Previous studies using the yeast two-hybrid assay (Y2H) have identified cyclin L1 (CCNL1) and Ewing sarcoma breakpoint region 1 protein (EWSR1) as being interacting partners of tuftelin-interacting protein 11 (TFIP11). …”
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613por Stuart, Philip E., Nair, Rajan P., Ellinghaus, Eva, Ding, Jun, Tejasvi, Trilokraj, Gudjonsson, Johann E., Li, Yun, Weidinger, Stephan, Eberlein, Bernadette, Gieger, Christian, Wichmann, H. Erich, Kunz, Manfred, Ike, Robert, Krueger, Gerald G., Bowcock, Anne M., Mroweitz, Ulrich, Lim, Henry W., Voorhees, John J., Abecasis, Goncalo R., Weichenthal, Michael, Franke, Andre, Rahman, Proton, Gladman, Dafna D., Elder, James T.“…Association at a genome-wide level of significance for the combined discovery and replication samples was found for three genomic regions. One contains NOS2 (rs4795067, p = 4 × 10(−11)), another contains FBXL19 (rs10782001, p = 9 × 10(−10)), and a third contains PSMA6 and NFKBIA (rs12586317, p = 2 × 10(−8)). …”
Publicado 2010
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614por Campo, David S., Dimitrova, Zoya, Yokosawa, Jonny, Hoang, Duc, Perez, Nestor O., Ramachandran, Sumathi, Khudyakov, Yury“…Using synthetic peptides and mouse immunization as a model, we conducted a quantitative analysis of cross-immunoreactivity among variants of the HCV hypervariable region 1 (HVR1). Analysis of 26,883 immunological reactions among pairs of peptides showed that the distribution of cross-immunoreactivity among HVR1 variants was skewed, with antibodies against a few variants reacting with all tested peptides. …”
Publicado 2012
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615por Gutierrez, M. Cristina, Ahmed, Niyaz, Willery, Eve, Narayanan, Sujatha, Hasnain, Seyed E., Chauhan, Devendra S., Katoch, Vishwa M., Vincent, Véronique, Locht, Camille, Supply, Philip“…A collection of 91 isolates originating from 12 different regions spread across the country were analyzed by genotyping using 21 loci with variable-number tandem repeats (VNTRs), by spoligotyping, by principal genetic grouping (PGG), and by deletion analysis of M. tuberculosis–specific deletion region 1. The isolates showed highly diverse VNTR genotypes. …”
Publicado 2006
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616por Mao, J-H, Wu, D, Kim, I-J, Kang, H C, Wei, G, Climent, J, Kumar, A, Pelorosso, F G, DelRosario, R, Huang, E J, Balmain, A“…Fine mapping of these LOH regions revealed three non-overlapping regions, one of which was refined to a 0.2 Mb interval that contained only the gene encoding homeobox-interacting protein kinase 2 (Hipk2). …”
Publicado 2012
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617por Cantile, Monica, Marra, Laura, Franco, Renato, Ascierto, Paolo, Liguori, Giuseppina, De Chiara, Annarosaria, Botti, Gerardo“…One of the genes most susceptible to breakage/translocation in soft tissue tumors is represented by Ewing sarcoma breakpoint region 1 (EWSR1). This gene has a large number of fusion partners, mainly associated with the pathogenesis of Ewing’s sarcoma but with other soft tissue tumors too. …”
Publicado 2013
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618por Luxton, Hayley J., Barnouin, Karin, Kelly, Gavin, Hanrahan, Sarah, Totty, Nick, Neal, David E., Whitaker, Hayley C.“…The localisation of LYRIC/AEG‐1 appears crucial to its function and is regulated by three lysine‐rich nuclear localisation signal regions, one of which was previously demonstrated to be modified by ubiquitin. …”
Publicado 2014
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619“…Here, we identified putative cis-regulatory elements (CREs) associated with male meiocyte-expressed genes using in silico tools. The upstream regions (1 kb) of the top 50 genes preferentially expressed in Arabidopsis meiocytes possessed conserved motifs. …”
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620por Herranz, Daniel, Ambesi-Impiombato, Alberto, Palomero, Teresa, Schnell, Stephanie A., Belver, Laura, Wendorff, Agnieszka A., Xu, Luyao, Castillo-Martin, Mireia, Llobet-Navás, David, Cardo, Carlos Cordon, Clappier, Emmanuelle, Soulier, Jean, Ferrando, Adolfo A.“…This highly conserved regulatory element, hereby named N-Me for NOTCH MYC enhancer, is located within a broad super-enhancer region +1.47 Mb from the MYC transcription initiating site, interacts with the MYC proximal promoter and induces orientation-independent MYC expression in reporter assays. …”
Publicado 2014
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