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Mostrando 921 - 940 Resultados de 1,076 Para Buscar '"Renaissance"', tiempo de consulta: 0.14s Limitar resultados
  1. 921
    por Hardie, D Grahame, Alessi, Dario R
    Publicado 2013
    “…While the idea that cancer is in part a metabolic disorder (first suggested by Warburg in the 1920s [4]) is well recognized today [5], this was not the case in 2003, and our paper perhaps contributed towards its renaissance. The aim of this short review is to recall how we made the original finding, and to discuss some of the directions that these findings have taken the field in the ensuing ten years.…”
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    LKB1 and AMPK and the cancer-metabolism link - ten years after
  2. 922
    por Maguire, J J, Davenport, A P
    Publicado 2014
    “…A third strategy based on activating the ET(B) receptor, has led to the renaissance of the modified peptide agonist IRL1620 as a clinical candidate in delivering anti-tumour drugs and as a pharmacological tool to investigate experimental pathophysiological conditions. …”
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    Endothelin@25 – new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12
  3. 923
    “…Undoubtedly, the last decade has also born a renaissance of immunotherapy, and encouraging advances in metastatic melanoma treatment are illuminating the road. …”
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    Combining Immunotherapy with Oncogene-Targeted Therapy: A New Road for Melanoma Treatment
  4. 924
    “…Today, following Cajal's school of thought, structural and functional investigations of microglial morphology, dynamics, and relationships with neurons and other glial cells are experiencing a renaissance and we stand at the brink of discovering new roles for these unique immune cells in the healthy brain, an essential step to understand their causal relationship to diseases.…”
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    From the Cajal alumni Achúcarro and Río-Hortega to the rediscovery of never-resting microglia
  5. 925
    “…Recent advances in training deep (multi-layer) architectures have inspired a renaissance in neural network use. For example, deep convolutional networks are becoming the default option for difficult tasks on large datasets, such as image and speech recognition. …”
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    Fast, Simple and Accurate Handwritten Digit Classification by Training Shallow Neural Network Classifiers with the ‘Extreme Learning Machine’ Algorithm
  6. 926
    “…To better understand this renaissance cell, it is essential to systematically survey what has been known in the literature about the cellular and molecular processes involved. …”
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    CARFMAP: A Curated Pathway Map of Cardiac Fibroblasts
  7. 927
    “…The last decade has witnessed a renaissance of empirical and psychological approaches to art study, especially regarding cognitive models of art processing experience. …”
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    Visualizing the Impact of Art: An Update and Comparison of Current Psychological Models of Art Experience
  8. 928
    “…Phenotypic screening is in a renaissance phase and is expected by many academic and industry leaders to accelerate the discovery of new drugs for new biology. …”
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    Open PHACTS computational protocols for in silico target validation of cellular phenotypic screens: knowing the knowns
  9. 929
    “…While Western artists start since the Renaissance to represent the world with a central perspective and focus on salient objects in a scene, Chinese artists concentrate on context information in their paintings, mainly before the mid-19th century. …”
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    Aesthetic Preferences for Eastern and Western Traditional Visual Art: Identity Matters
  10. 930
    “…Moreover, they may also pave the way for the renaissance of classical neuroprotective paradigms. …”
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    Recent progress in translational research on neurovascular and neurodegenerative disorders
  11. 931
    “…Although infective endocarditis (IE) has been described in reports dating from the Renaissance, the diagnosis still challenges and the outcome often surprises. …”
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    Infective endocarditis with left to right intracardiac fistula due to Streptococcus anginosus - a rare complication caused by an even rarer bacterium
  12. 932
    “…For communities undergoing fast-paced innovation, researchers need new capabilities to share, obtain feedback, and publish methods at the forefront of scientific development. For example, a renaissance in virology is now underway given the new metagenomic methods to sequence viral DNA directly from an environment. …”
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    Method-centered digital communities on protocols.io for fast-paced scientific innovation
  13. 933
    “…Participants viewed a range of image types—Abstract, Hyperrealistic, Poorly Executed paintings, Readymade sculptures, as well as Renaissance and Baroque paintings. They classified these as “art” or “not art” using both binary and analog scales, and also assessed for liking. …”
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    But Is It really Art? The Classification of Images as “Art”/“Not Art” and Correlation with Appraisal and Viewer Interpersonal Differences
  14. 934
    “…The use of peptides as therapeutic agents is undergoing a renaissance with the expectation of new drugs with enhanced levels of efficacy and safety. …”
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    Controlling the bioactivity of a peptide hormone in vivo by reversible self-assembly
  15. 935
    por Molla, Gianluca
    Publicado 2017
    “…In particular, the correlation between reduced D-Ser concentration and SZ led to a renaissance of biochemical interest in human DAAO (hDAAO). …”
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    Competitive Inhibitors Unveil Structure/Function Relationships in Human D-Amino Acid Oxidase
  16. 936
    “…Over the two past decades, there has been a growing body of preclinical evidence supporting the immunomodulatory effects of radiotherapy, particularly when combined with immunotherapy, but only anecdotal clinical examples existed until recently. The renaissance of immunotherapy and the recent U.S. Food and Drug Administration (FDA) approval of several immune checkpoint inhibitors (ICIs) and other immuno-oncology (IO) agents in multiple cancers provides the opportunity to investigate how localized radiotherapy can induce systemic immune responses. …”
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    Incorporating Radiation Oncology into Immunotherapy: proceedings from the ASTRO-SITC-NCI immunotherapy workshop
  17. 937
    por Huang, Xiongyi, Groves, John T.
    Publicado 2017
    “…Given the recent developments in biocatalysis for non-natural chemistries and the renaissance of radical chemistry in organic synthesis, we envision that new enzymatic and synthetic transformations will emerge based on the radical processes mediated by metalloproteins and their synthetic analogs.…”
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    Oxygen Activation and Radical Transformations in Heme Proteins and Metalloporphyrins
  18. 938
    “…Research on the NVU has recently seen a renaissance to especially understand the neurobiology of vascular and brain pathologies and their frequently occurring comorbidities. …”
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    The Blood-Brain Barrier and the EphR/Ephrin System: Perspectives on a Link Between Neurovascular and Neuropsychiatric Disorders
  19. 939
    “…Our findings support the renaissance of acarbose as a useful adjunct in diabetic patients with stage 5 and 5D chronic kidney disease.…”
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    Acarbose Use and Liver Injury in Diabetic Patients With Severe Renal Insufficiency and Hepatic Diseases: A Propensity Score-Matched Cohort Study
  20. 940
    “…This area has created a renaissance in Inorganic Chemistry. From the synthetic Inorganic Chemistry viewpoint, the early years of “try and see” exercises (1993–2000) have been followed by the development of strategies and strict approaches. …”
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    Coordination Clusters of 3d-Metals That Behave as Single-Molecule Magnets (SMMs): Synthetic Routes and Strategies
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