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7941por Ascierto, Paolo A., Brugarolas, James, Buonaguro, Luigi, Butterfield, Lisa H., Carbone, David, Daniele, Bruno, Ferris, Robert, Fox, Bernard A., Galon, Jérôme, Gridelli, Cesare, Kaufman, Howard L., Klebanoff, Christopher A., Melero, Ignacio, Nathan, Paul, Paulos, Chrystal M., Ruella, Marco, Sullivan, Ryan, Zarour, Hassane, Puzanov, Igor“…The clinical success of anti-cytotoxic T-lymphocyte-associated antigen (CTLA)-4, first, and anti-programmed death (PD)-1/PD-ligand (L)1 agents in melanoma and other cancers a few years later, has encouraged increasing focus on the development of other immunotherapies (e.g. monoclonal antibodies with other immune targets, adoptive cell transfer, and vaccines), with over 3000 immuno-oncology trials ongoing, involving hundreds of research institutes across the globe. The potential use of these different immunotherapeutic options in various combinations with one another and with other treatment modalities is an area of particular promise. …”
Publicado 2018
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7942“…The work has empowered collaborative research across competing organizations and brought together researchers from clinical practice, universities and research institutes around the planet. Understanding the eco-system of data models designed for collaborative research allows readers to evaluate where we have been, where we are going as a field, and to evaluate the utility of different models to their own work.…”
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7943por Singh, Gerald G, Farjalla, Vinicius F, Chen, Bing, Pelling, Andrew E, Ceyhan, Elvan, Dominik, Martin, Alisic, Eva, Kerr, Jeremy, Selin, Noelle E, Bassioni, Ghada, Bennett, Elena, Kemp, Andrew H, Chan, Kai MA“…On the basis of data from an international survey of 1092 participants (634 established researchers and 458 students) in 55 countries and 315 research institutions, we found that institutional recognition of engagement activities is perceived to be undervalued relative to the societal benefit of those activities. …”
Publicado 2019
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7944“…Analyses on topical trends, correlations, and clusters reveal distinct developmental trends of these topics, promising research orientations, and diverse topical distributions in influential countries/regions and research institutes. These findings help better understand scientific and technological AI-assisted human brain research, provide insightful guidance for resource (re)allocation, and promote effective international collaborations.…”
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7945“…The novel coronavirus (COVID-19) pandemic has become a real challenge for healthcare providers around the world and has significantly affected the dental professionals in practices, universities and research institutions. The aim of this article was to review the available literature on the relevant aspects of dentistry in relation to COVID-19 and to discuss potential impacts of COVID-19 outbreak on clinical dentistry, dental education and research. …”
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7946por Dutta, Ashok Kumar“…Normally any new vaccine development takes 10–15 y time but the search for vaccine against SARS-CoV2 is going on at a very fast pace resulting in almost breakthrough in vaccine development by several research institutions and vaccine manufacturers. In pandemic situation, however, the entire process of vaccine development including clinical trials gets shortened and may be fast tracked to 15–18 mo time. …”
Publicado 2020
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7947“…The government of Nepal (GoN) has established different scientific departments, universities, and research institutions, and has tried to emphasize the application of science and research for the development of the nation. …”
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7948“…In this strategy, safety is taken in a broader sense including not only issues of technical precaution of avoiding risks of experimentation but also the societal responsibility of researchers and research institutes of identifying possible future risks. …”
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7949“…This study examines long-term ocean pH data to evaluate ocean acidification (OA) trends at two coastal research institutions located on the Sea of Japan and the Pacific Ocean. …”
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7950por Basso, M.A., Frey, S., Guerriero, K.A., Jarraya, B., Kastner, S., Koyano, K.W., Leopold, D.A., Murphy, K., Poirier, C., Pope, W., Silva, A.C., Tansey, G., Uhrig, L.“…Simultaneously, with access to MRI in many research institutions, MRI has become an indispensable tool for researchers and veterinarians to guide improvements in surgical procedures and implants and thus, experimental as well as clinical outcomes, given that access to MRI also allows for improved diagnosis and monitoring for brain disease. …”
Publicado 2020
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7951por Usmani, Muhammad Shahjahan, Wang, Jianling, Ahmad, Naveed, Iqbal, Muzaffar, Ahmed, Rahil Irfan“…The implications of this research offer wide directives for editors, researchers, research institutions, policymakers, and practitioners.…”
Publicado 2021
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7952“…Because of these reasons, most research institutes set up centralized core facilities where custom GEMs are created for research groups. …”
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7953“…Cooperative network analysis shows that the United States, the University of Toronto and Roger S Mcintyre are the most influential countries, research institutes and scholars, respectively. Insulin resistance, obesity, and metabolic syndrome are hot topics in this field. …”
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7954“…We find: (1) the elasticity of R&D effort with respect to market size is about 1/2 in the cross-section of diseases; (2) given this elasticity, the R&D response to COVID-19 has been 4 to 26 times greater than that implied by its market size; (3) the aggregate short-term elasticity of science and innovation can be very large, as demonstrated by the aggregate flow of clinical trials increasing by 38% in 2020, with limited crowding out of trials for non-COVID diseases; and (4) public institutions and government-led incentives were a key driver of the COVID-19 R&D effort—with public research institutions accounting for 70 percent of all COVID-19 clinical trials globally. …”
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7955por Grube, Maike M., Scheidt-Nave, Christa, Gaertner, Beate, Lüdtke, Denise, Bosnjak, Michael, Heinrich, Stephanie, Lahmann, Nils, Meyer, Gabriele, Rapp, Kilian, Riedel-Heller, Steffi, Schäufele, Martina, Wolf-Ostermann, Karin, Zank, Susanne, Fuchs, Judith“…Data sources that can be used for the indicators are the health surveys within the framework of the Robert Koch Institute’s (RKI) health monitoring system, as well as surveys from other research institutes and official statistics. In the future, the indicator set is to be developed further and integrated into an overall approach that is geared towards health reporting and the monitoring of chronic diseases in all phases of life.…”
Publicado 2019
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7956por Farquhar, Rachael, Dori, Annie, MacCana, Sarah, Tefuarani, Nakapi, Lavu, Evelyn, Barry, Alyssa, Karl, Stephan, Makita, Leo, Robinson, Leanne, Laman, Moses“…This case study, centred on the STRIVE PNG project, describes how a partnership-based approach has been used to establish, maintain and review effective and equitable relationships between 13 partner organizations (independent research institutes, government health agencies and public health laboratories) to strengthen surveillance and health systems in Papua New Guinea (PNG). …”
Publicado 2022
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7957por Mtewa, Andrew G., Amanjot, Annu, Lampiao, Fanuel, Okella, Hedmon, Weisheit, Anke, Tolo, Casim U., Ogwang, Patrick“…Vaccine development against the disease was accelerated with multiple collaborations among research institutions in order to shorten the duration that vaccine development normally takes. …”
Publicado 2022
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7958“…Colorado State Univ, Texas a&m Univ, and Delft Univ Technol are the main research institutions. The keyword analysis indicates the hot topics in different periods. …”
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7959“…Limited collaboration among countries was observed, but robust collaboration among the research institutions and authors.…”
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7960por Klugah-Brown, Benjamin, Yu, Yue, Hu, Peng, Agoalikum, Elijah, Liu, Congcong, Liu, Xiqin, Yang, Xi, Zeng, Yixu, Zhou, Xinqi, Yu, Xin, Rypma, Bart, Michael, Andrew M., Li, Xiaobo, Becker, Benjamin, Biswal, Bharat“…Wearing a face mask has become essential to contain the spread of COVID-19 and has become mandatory when collecting fMRI data at most research institutions. Here, we investigate the effects of wearing a surgical mask on fMRI data in n = 37 healthy participants. …”
Publicado 2022
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