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2881“…Vaccines in development to protect against additional infectious diseases causing significant morbidity and mortality in older adults, such as respiratory syncytial virus, can further promote healthy aging. …”
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2882por Geiser, Johan, Boivin, Guy, Huang, Song, Constant, Samuel, Kaiser, Laurent, Tapparel, Caroline, Essaidi-Laziosi, Manel“…We studied Respiratory Syncytial virus (RSV) and human Metapneumovirus (HMPV) in single and dual infections in three-dimensional cultures, a highly relevant model to study viral respiratory infections of the airway epithelium. …”
Publicado 2021
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2883“…Most infections are caused by respiratory syncytial virus (RSV), but the importance of Mycoplasma pneumoniae (MP) in the etiology of bronchiolitis is unclear. …”
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2884por Frétaud, Maxence, Descamps, Delphyne, Laubreton, Daphné, Rameix-Welti, Marie-Anne, Eléouët, Jean-François, Larcher, Thibaut, Galloux, Marie, Langevin, Christelle“…Background: Respiratory Syncytial Virus (RSV) is the major cause of severe acute respiratory tract illness in young children worldwide and a main pathogen for the elderly and immune-compromised people. …”
Publicado 2021
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2885por Mastrangelo, Peter, Chin, Allysia A., Tan, Stephanie, Jeon, Amy H., Ackerley, Cameron A., Siu, Karen K., Lee, Jeffrey E., Hegele, Richard G.“…Nucleolin is an essential cellular receptor to human respiratory syncytial virus (RSV). Pharmacological targeting of the nucleolin RNA binding domain RBD1,2 can inhibit RSV infections in vitro and in vivo; however, the site(s) on RBD1,2 which interact with RSV are not known. …”
Publicado 2021
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2886“…This article provides an overview of antiviral classifications in 10 important human viruses: hepatitis B virus (HBV), hepatitis C virus (HCV), human immunodeficiency virus (HIV), human cytomegalovirus (HCMV), herpes simplex virus (HSV), variola virus (human smallpox), varicella zoster virus (VZV), influenza virus, respiratory syncytial virus (RSV), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).…”
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2887por Mayor, Alexie, Chesnay, Adélaïde, Desoubeaux, Guillaume, Ternant, David, Heuzé-Vourc’h, Nathalie, Sécher, Thomas“…RTIs implicate microorganisms, including viruses (influenza virus, coronavirus, respiratory syncytial virus (RSV)), bacteria (Pseudomonas aeruginosa, Streptococcus pneumoniae, Staphylococcus aureus and Bacillus anthracis) and fungi (Pneumocystis spp., Aspergillus spp. and very occasionally Candida spp.). …”
Publicado 2021
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2888por Pavot, Vincent, Bisceglia, Hélène, Guillaume, Florine, Montano, Sandrine, Zhang, Linong, Boudet, Florence, Haensler, Jean“…In this article, using the Respiratory Syncytial Virus (RSV) nanoparticulate prefusion F model antigen developed by Sanofi, we demonstrate in the macaque model that the polyacrylate (PAA)-based adjuvant SPA09 is well tolerated and increases vaccine antigen-specific humoral immunity (sustained neutralizing antibodies, memory B cells and mucosal immunity) and elicits strong T(H)1-type responses (based on IFNγ and IL-2 ELISpots) in a dose-dependent manner. …”
Publicado 2021
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2889“…Respiratory Syncytial Virus (RSV) and Influenza cause a large burden of disease. …”
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2890“…This pattern of infection is quite distinct from the acute/resolving nature of other human pathogenic respiratory viruses, such as influenza A virus and respiratory syncytial virus. Prolonged shedding of SARS-CoV-2 furthermore occurs irrespective of disease severity or development of virus-neutralizing antibodies. …”
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2891“…Human respiratory syncytial virus (HRSV), human metapneumovirus (HMPV), and human parainfluenza viruses (HPIVs) are leading causes of respiratory disease in young children, the elderly, and individuals of all ages with immunosuppression. …”
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2892“…CONCLUSION: The measures used to control the SARSCoV-2 infection have also affected the community circulation of most respiratory viruses including influenza and respiratory syncytial virus.…”
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2893por Caballero, Mauricio T, Satav, Ashish, Gill, Christopher J, Omer, Saad B, Pieciak, Rachel C, Kazi, Abdul Momin, Simões, Eric Af, Polack, Fernando P“…BACKGROUND: Estimating the real impact of respiratory syncytial virus (RSV) disease is key for the development of vaccines and treatments. …”
Publicado 2021
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2894por Liu, Dan, Tang, Zhongxiang, Qiu, Kezi, Bajinka, Ousman, Wang, Lili, Qin, Ling, Tan, Yurong“…BACKGROUND: Respiratory syncytial virus (RSV) infects infants and children, predisposing them to development of asthma during adulthood. …”
Publicado 2021
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2895“…Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory tract infections (LRTIs) in infants. …”
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2896por Vlahopoulos, Spiros, Wang, Ke, Xue, Yaoyao, Zheng, Xu, Boldogh, Istvan, Pan, Lang“…The bronchial vascular endothelial network plays important roles in pulmonary pathology during respiratory viral infections, including respiratory syncytial virus (RSV), influenza A(H1N1) and importantly SARS-Cov-2. …”
Publicado 2021
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2897por McCall, Matthew N., Chu, Chin-Yi, Wang, Lu, Benoodt, Lauren, Thakar, Juilee, Corbett, Anthony, Holden-Wiltse, Jeanne, Slaunwhite, Christopher, Grier, Alex, Gill, Steven R., Falsey, Ann R., Topham, David J., Caserta, Mary T., Walsh, Edward E., Qiu, Xing, Mariani, Thomas J.“…Respiratory syncytial virus (RSV) infection results in millions of hospitalizations and thousands of deaths each year. …”
Publicado 2021
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2898“…Human respiratory syncytial virus (hRSV) infection brings a wide spectrum of clinical outcomes, from a mild cold to severe bronchiolitis or even acute interstitial pneumonia. …”
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2899“…The development of human respiratory syncytial virus (hRSV) vaccine has been hampered by the risk of enhanced respiratory disease (ERD) which was induced by highly skewed toward Th2 immune response. …”
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2900“…Respiratory syncytial virus (RSV) is the leading cause of severe acute lower respiratory tract infections in infants worldwide. …”
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