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641“…Ancestral gene duplications led to five well-defined groups with distinct substrate specificity, allowing these beetles to break down, in addition to cellulose, polysaccharides that are abundant in plant cell walls (PCWs), namely, xyloglucan, xylan, and mannans. Resurrecting the ancestral enzyme originally acquired by HGT, we show it was a cellulase that was able to break down glucomannan and xylan. …”
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642por Lazzari, Grazia, Giua, Renato, Verdolino, Elisabetta, Solazzo, Angela Pia, Benevento, Ilaria, Montagna, Antonietta, Castaldo, Giovanni, Rago, Luciana, Silvano, Giovanni“…The COVID-19 pandemic has opened several new disease scenarios, yielding novel syndromes that have never been seen before and resurrecting old inflammatory phenomena that are no longer recorded, such as radiation recall (RR) syndromes. …”
Publicado 2022
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643por Gutierrez-Rus, Luis I., Alcalde, Miguel, Risso, Valeria A., Sanchez-Ruiz, Jose M.“…Most modern proteins are highly evolved and specialized and, consequently, difficult to repurpose for completely new functionalities. Conceivably, resurrected ancestral proteins with the biophysical properties that promote evolvability, such as high stability and conformational diversity, could provide better scaffolds for de novo enzyme generation. …”
Publicado 2022
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644por Xu, Hai-Feng, Dai, Guo-Zheng, Bai, Yang, Shang, Jin-Long, Zheng, Bin, Ye, De-Min, Shi, Huazhong, Kaplan, Aaron, Qiu, Bao-Sheng“…The regulatory mechanisms that enable their vegetative cells to resurrect upon rehydration are poorly understood. In this study, we identified a single gene family of high light-inducible proteins (Hlips) with dramatic expansion in the Nostoc flagelliforme genome and found an intriguingly special convergence formed through four tandem gene duplication. …”
Publicado 2022
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645por Gordin, Michael D“…In The Pseudoscience Wars, Michael D. Gordin resurrects the largely forgotten figure of Velikovsky and uses his strange career and surprisingly influential writings to explore the changing definitions of the line that separates legitimate scientific inquiry from what is deemed bunk, and to show how vital this question remains to us today. …”
Publicado 2012
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646“…The matching TCR chains from individual T cells can be resurrected in hybridoma cells which may then be used for antigen searches. …”
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647por Lal, Jham, Biswas, Pradyut, Singh, Soibam Khogen, Debbarma, Reshmi, Mehta, Naresh Kumar, Deb, Suparna, Sharma, Sanjeev, Waikhom, Gusheinzed, Patel, Arun Bhai“…To resurrect and establish a low-impact aquaculture practice, gel-based feed applications hold promise. …”
Publicado 2023
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648“…Nesticellaterrestris (Yaginuma, 1970) is resurrected as a valid species and distinguished from the closely related N.brevipes based on morphological and molecular evidence. …”
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649“…In February 2007 the organization was officially resurrected and the launch of the first mass media campaign of the "new" ParticipACTION occurred in October 2007. …”
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650“…As expected, substitutions in human MTHFR at sites that are well-conserved across distant orthologs result in an impaired enzyme, while substitutions present in recently diverged sequences (including a 9-site mutant that “resurrects” the human-macaque ancestor) result in a functional enzyme. …”
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651por Kim, Song-Min, Bhonsle, Latika, Besgen, Petra, Nickel, Jens, Backes, Anna, Held, Kathrin, Vollmer, Sigrid, Dornmair, Klaus, Prinz, Joerg C.“…It should facilitate essential new insights into the mechanisms of protective and pathologic immunity in many human T-cell mediated conditions and allow for resurrecting functional TCRs from any αβ-T cell of choice that can be used for investigating their specificity.…”
Publicado 2012
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652por Pei, Baikang, Sisu, Cristina, Frankish, Adam, Howald, Cédric, Habegger, Lukas, Mu, Xinmeng Jasmine, Harte, Rachel, Balasubramanian, Suganthi, Tanzer, Andrea, Diekhans, Mark, Reymond, Alexandre, Hubbard, Tim J, Harrow, Jennifer, Gerstein, Mark B“…On the other hand, we find interesting patterns of partial activity, which may suggest that dead genes are being resurrected as functioning non-coding RNAs. The activity data of each pseudogene are stored in an associated resource, psiDR, which will be useful for the initial identification of potentially functional pseudogenes.…”
Publicado 2012
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653“…Based on these molecular evidence and biogeographical scenario we suggest that the genus Dravidogecko should be resurrected.…”
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654“…COaLA efficiently estimates ancestral amino acid frequencies and sequences, making it relevant for studies aiming at reconstructing and resurrecting ancestral amino acid sequences. Finally, we applied COaLA on a concatenate of universal amino acid sequences to confirm previous results obtained with a nonhomogeneous Bayesian model regarding the early pattern of adaptation to optimal growth temperature, supporting the mesophilic nature of the Last Universal Common Ancestor. …”
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655“…This classification includes new, resurrected, and modified subfamilies within gymnophthalmid and scincid lizards, and boid, colubrid, and lamprophiid snakes.…”
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656“…CONCLUSIONS: A revised classification based on the molecular phylogeny is proposed that includes seven tribes and also defines monophyletic genera, including a resurrected genus Eretmobrycon, and new definitions for Diapoma, Hemibrycon, Bryconamericus sensu stricto, and Knodus sensu stricto, placing some small genera as junior synonyms. …”
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657por Tanaka, K., Hirayama, K., Yonezawa, H., Sato, G., Toriyabe, A., Kudo, H., Hashimoto, A., Matsumura, M., Harada, Y., Kurihara, Y., Shirouzu, T., Hosoya, T.“…The genus Periconia and its relatives are segregated from the Massarinaceae and placed in a resurrected family, the Periconiaceae. We have summarised the morphological and ecological features, and clarified the accepted members of each family. …”
Publicado 2015
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658“…In particular, this approach allows investigators to (1) reconstruct and “resurrect” (that is, synthesize in vivo or in vitro) extinct proteins to study how they differ from modern proteins, (2) identify key amino acid changes that, over evolutionary timescales, have altered the function of the protein, and (3) order historical events in the evolution of protein function. …”
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659por Kacar, Betül, Garmendia, Eva, Tuncbag, Nurcan, Andersson, Dan I., Hughes, Diarmaid“…The ancestral homologs represented phylogenetically resurrected tuf sequences dating from 0.7 to 3.6 billion years ago (bya). …”
Publicado 2017
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660por Summers, Jennifer L., Bernik, Brittany, Saunders, Colin J., McLachlan, Jason S., Blum, Michael J.“…After assembling profiles of the seed bank from radionuclide‐dated soil cores, we germinated seeds to “resurrect” cohorts spanning the 20th century. Using microsatellite markers, we assessed genetic diversity and differentiation among depth cohorts, drawing comparisons to extant plants at the study site and in nearby and more distant marshes. …”
Publicado 2018
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