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  1. 20241
    “…BACKGROUND: Circadian clocks are biological oscillators that regulate molecular, physiological, and behavioral rhythms in a wide variety of organisms. While behavioral rhythms are typically monitored over many cycles, a similar approach to molecular rhythms was not possible until recently; the advent of real-time analysis using transgenic reporters now permits the observations of molecular rhythms over many cycles as well. …”
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    Signal analysis of behavioral and molecular cycles
  2. 20242
    “…Mobile measures of human circadian rhythms (CR) are needed in the age of chronotherapy. …”
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    Distinct Circadian Assessments From Wearable Data Reveal Social Distancing Promoted Internal Desynchrony Between Circadian Markers
  3. 20243
    “…In contrast to robust PER2 circadian rhythms in cardiomyocytes, we detected no rhythms in contraction rate and only weak rhythms in basal Ca(2+) level. …”
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    Cardiomyocyte Circadian Oscillations Are Cell-Autonomous, Amplified by β-Adrenergic Signaling, and Synchronized in Cardiac Ventricle Tissue
  4. 20244
    “…Circadian rhythms play a crucial role in the health and survival of organisms. …”
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    Extrinsic and intrinsic factors influencing the emergence and return of the Asian particolored bat Vespertilio sinensis to the summer roost
  5. 20245
    por Frank, Marcos G.
    Publicado 2016
    “…Circadian rhythms refer to oscillations in biological processes with a period of approximately 24 h. …”
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    Circadian Regulation of Synaptic Plasticity
  6. 20246
    “…Circadian rhythms describe physiological systems that repeat themselves with a cycle of approximately 24 h. …”
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    Circadian Effects of Drug Responses
  7. 20247
    por McGinnis, Graham R, Young, Martin E
    Publicado 2016
    “…Robust circadian rhythms in metabolic processes have been described in both humans and animal models, at the whole body, individual organ, and even cellular level. …”
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    Circadian regulation of metabolic homeostasis: causes and consequences
  8. 20248
    “…Latitudinal clines in circadian rhythms have consistently been described in various plant species, with the most recent examples appearing in soybean cultivars and in monkey flower natural populations. …”
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    The timing of GIGANTEA expression during day/night cycles varies with the geographical origin of Arabidopsis accessions
  9. 20249
    “…Adipocyte circadian clocks drive rhythms in gene expression, and dysregulation of these circadian rhythms associates with pathological conditions such as diabetes. …”
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    In vitro characterisation of murine pre‐adipose nucleated cells reveals electrophysiological cycles associated with biological clocks
  10. 20250
    “…Here we report the generation of an artificial, mammalian circadian clock in vivo, capable of generating robust, tunable circadian rhythms. In mice deficient in Per1 and Per2 genes (thus lacking circadian rhythms), we artificially generate PER2 rhythms and restore circadian sleep/wake cycles with an inducible Per2 transgene. …”
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    A tunable artificial circadian clock in clock-defective mice
  11. 20251
    “…Daily rhythms in behaviour, physiology and molecular processes are expected to enable organisms to appropriately schedule activities according to consequences of the daily rotation of the Earth. …”
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    Adaptive periodicity in the infectivity of malaria gametocytes to mosquitoes
  12. 20252
    “…Every cell contains a CLOCK: BMAL1 loop for the generation of circadian rhythms. In this review, we focused on cell autonomous circadian rhythms in immune cells, the inflammatory diseases caused by disruption of circadian rhythms in hormones, and the role of clock genes in inflammatory diseases.…”
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    Cell Autonomous Circadian Systems and Their Relation to Inflammation
  13. 20253
    “…The kidney is the site of one of the most active peripheral clocks. Biological rhythms, of which the best known are circadian rhythms, are required for normal physiology of the kidneys and other organs. …”
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    Chronodisruption: A Poorly Recognized Feature of CKD
  14. 20254
    “…We found daily rhythms of metabolite levels and flux through glycolysis and the pentose phosphate pathway (PPP). …”
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    Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells
  15. 20255
    “…Compositional oscillations of the gut microbiome are essential for normal peripheral circadian rhythms, both of which are disrupted in diet-induced obesity (DIO). …”
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    Diet and feeding pattern modulate diurnal dynamics of the ileal microbiome and transcriptome
  16. 20256
    “…In mammals, circadian rhythms of various organs and tissues are synchronized by pacemaker neurons in the suprachiasmatic nucleus (SCN) of the hypothalamus. …”
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    A Dual-Color Luciferase Assay System Reveals Circadian Resetting of Cultured Fibroblasts by Co-Cultured Adrenal Glands
  17. 20257
    “…INTRODUCTION: Dysregulation of circadian rhythms is a key symptom of mood disorders, including anxiety disorders and depression. …”
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    Circadian abnormalities in a mouse model of high trait anxiety and depression
  18. 20258
    por Caba, Mario, Mendoza, Jorge
    Publicado 2018
    “…Disruption of these genes leads to a malfunctioning clockwork and behavioral and physiological rhythms are altered. In addition to synchronization of circadian rhythms by light, when subjects are exposed to food for a few hours daily, behavioral and physiological rhythms are entrained to anticipate mealtime, even in the absence of the SCN. …”
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    Food-Anticipatory Behavior in Neonatal Rabbits and Rodents: An Update on the Role of Clock Genes
  19. 20259
    “…A number of studies point to slow (0.1–2 Hz) brain rhythms as the basis for the resting-state functional magnetic resonance imaging (rsfMRI) signal. …”
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    Selective blockade of rat brain T-type calcium channels provides insights on neurophysiological basis of arousal dependent resting state functional magnetic resonance imaging signals
  20. 20260
    por Lee, Yool
    Publicado 2021
    “…Circadian clocks are ubiquitous timing mechanisms that generate approximately 24-h rhythms in cellular and bodily functions across nearly all living species. …”
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    Roles of circadian clocks in cancer pathogenesis and treatment
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