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  1. 20761
    “…The 12-h clock coordinates lipid homeostasis, energy metabolism, and stress rhythms via the transcriptional regulator XBP1. However, the biochemical and physiological bases for integrated control of the 12-h clock and diverse metabolic pathways remain unclear. …”
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    Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism
  2. 20762
    por Sato, Tomoki, Sassone‐Corsi, Paolo
    Publicado 2022
    “…Circadian rhythms are controlled by the biological clock, a molecular system remarkably conserved throughout evolution. …”
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    Nutrition, metabolism, and epigenetics: pathways of circadian reprogramming
  3. 20763
    “…Circadian rhythms regulate a host of physiological processes in a time-dependent manner to maintain homeostasis in response to various environmental stimuli like day and night cycles, food intake, and physical activity. …”
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    Time to Train: The Involvement of the Molecular Clock in Exercise Adaptation of Skeletal Muscle
  4. 20764
    “…In humans, an adaptable internal biological system generates circadian rhythms that maintain synchronicity of behavior and physiology with the changing demands of the 24-h environment. …”
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    Development of the circadian system in early life: maternal and environmental factors
  5. 20765
    “…Sleep is generally considered to be a state of large-scale synchrony across thalamus and neocortex; however, recent work has challenged this idea by reporting isolated sleep rhythms such as slow oscillations and spindles. What is the spatial scale of sleep rhythms? …”
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    Waveform detection by deep learning reveals multi-area spindles that are selectively modulated by memory load
  6. 20766
    por Glavind, Ida Marie Lind
    Publicado 2022
    “…Alzheimer’s disease entails living with desynchronized rhythms, time that can be made painfully explicit, and numbers becoming increasingly tricky to manage. …”
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    Temporal Belonging: Loss of Time and Fragile Attempts to Belong with Alzheimer’s Disease
  7. 20767
    “…Several studies have indicated that coherent circadian rhythms in behaviour can be manifested only when the underlying circadian oscillators function as a well-coupled network. …”
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    A new player in circadian networks: Role of electrical synapses in regulating functions of the circadian clock
  8. 20768
    por Zhang, Rui, Volkow, Nora D.
    Publicado 2023
    “…Changes in circadian rhythms are likely to prominently mediate these seasonal effects since light strongly entrains the internal clock modifying brain function. …”
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    Seasonality of brain function: role in psychiatric disorders
  9. 20769
    “…Moreover, the addition of the CK1δ/ε inhibitor disrupted rhythms of aanat2 mRNA expression in the pineal gland. …”
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    Casein Kinase 1δ Activity: A Key Element in the Zebrafish Circadian Timing System
  10. 20770
    “…Fluctuations of animal counts in linear video-transects conducted with the Internet Operated Deep-Sea Crawler “Wally” in June, July and December of 2013, were used as proxy of population activity rhythms. Count time series and environmental parameters were analyzed under the hypothesis that the environmental conditioning of activity rhythms depends on the life habits of particular species (i.e. movement type and trophic level). …”
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    High-Frequency Patterns in the Abundance of Benthic Species near a Cold-Seep – An Internet Operated Vehicle Application
  11. 20771
    “…The circadian rhythms and sleep efficiency of the selected chronotypes were further tested under such extreme conditions as either long day (LD20:4 at 20°C) or a combination of LD20:4 with hot temperature (29°C). …”
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    Larks, owls, swifts, and woodcocks among fruit flies: differential responses of four heritable chronotypes to long and hot summer days
  12. 20772
    “…From an epidemiological standpoint, disruptions to circadian rhythms have been shown to contribute to the development of various disease pathologies, including breast cancer. …”
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    Analyses of BMAL1 and PER2 Oscillations in a Model of Breast Cancer Progression Reveal Changes With Malignancy
  13. 20773
    por Cavieres-Lepe, Javier, Ewer, John
    Publicado 2021
    “…At the molecular level, circadian rhythms are driven by intracellular transcriptional/translational feedback loops (TTFL). …”
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    Reciprocal Relationship Between Calcium Signaling and Circadian Clocks: Implications for Calcium Homeostasis, Clock Function, and Therapeutics
  14. 20774
    “…Finally, the phase of both ongoing rhythms also appeared to be an important factor in modulating HPC responses, with maximal field excitatory postsynaptic potentials (EPSPs) occurring during the negative-going phase of both rhythms. …”
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    Prefrontal-Hippocampal Pathways Through the Nucleus Reuniens Are Functionally Biased by Brain State
  15. 20775
    “…RECENT FINDINGS: Dysregulation of sleep and circadian rhythms has been established in several psychiatric and neurocognitive disorders for long. …”
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    Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness
  16. 20776
    “…Circadian clocks are ∼24-h timekeepers that control rhythms in almost all aspects of our behavior and physiology. …”
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    Streamlined single-molecule RNA-FISH of core clock mRNAs in clock neurons in whole mount Drosophila brains
  17. 20777
    “…Obesity, as an environmental cue, alters circadian rhythms. The hypothesis of this study was that consumption of a high-fat diet alters metabolic rhythms in pubertal mice. …”
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    Consumption of a high-fat diet alters transcriptional rhythmicity in liver from pubertal mice
  18. 20778
    “…These studies demonstrated that ELF3 forms part of the circadian oscillator; however, the loss of all homoeologues was required to affect circadian rhythms. Similarly, loss of functional LUX ARRHYTHMO (LUX) in T. aestivum, an orthologue of a protein partner of Arabidopsis (Arabidopsis thaliana) ELF3, severely disrupted circadian rhythms. …”
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    Wheat EARLY FLOWERING 3 affects heading date without disrupting circadian oscillations
  19. 20779
    por Davis, Seth J, Millar, Andrew J
    Publicado 2001
    “…Genes involved in signal transduction and in various metabolic pathways were found to be coordinately regulated by circadian rhythms and/or by light.…”
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    Watching the hands of the Arabidopsis biological clock
  20. 20780
    “…The synchronization of multiple oscillators serves as the central mechanism for maintaining stable circadian rhythms in physiology and behavior. Aging and disease can disrupt synchronization, leading to changes in the periodicity of circadian activities. …”
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    Weak synchronization can alter circadian period length: implications for aging and disease conditions
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