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  1. 21061
    “…Disrupted circadian rhythms is a prominent and early feature of neurodegenerative diseases including Huntington’s disease (HD). …”
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    Ataxin2 functions via CrebA to mediate Huntingtin toxicity in circadian clock neurons
  2. 21062
    “…The altered expression of hypothalamic molecular clock components and appetite genes, together with changes in activity and feeding rhythms, could be contributing to offspring obesity.…”
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    Maternal Obesity during Pregnancy Alters Daily Activity and Feeding Cycles, and Hypothalamic Clock Gene Expression in Adult Male Mouse Offspring
  3. 21063
    “…Protein−protein interaction analyses revealed that the hub genes were primarily associated with pathway in cancer and circadian rhythms. Expression validation showed that while the expression levels of miR-195 and miR-340 were up-regulated, the rhythms of these two miRNAs were always maintained. …”
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    Analysis of miRNA expression profiles in the liver of Clock(Δ19) mutant mice
  4. 21064
    “…Scleractinian corals, the framework builders of coral reefs, depend on lunar illumination cues to synchronize their biological rhythms such as behavior, reproduction and physiology. …”
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    Red Sea corals under Artificial Light Pollution at Night (ALAN) undergo oxidative stress and photosynthetic impairment
  5. 21065
    “…The “5d + 2d” shifting LD schedule led to a disruption in wheel‐running activity (WRA) and body temperature (Tb) rhythms which manifested up to three separate periods in the circadian range. …”
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    Melatonin alleviates circadian system disruption induced by chronic shifts of the light‐dark cycle in Octodon degus
  6. 21066
    “…Night-shift work alters the body’s exposure to the natural light–dark schedule and disrupts circadian (daily) rhythms. The greatest effect of night-shift work is the disruption of circadian rhythms. …”
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    Night-Time Shift Work and Related Stress Responses: A Study on Security Guards
  7. 21067
    “…Circadian rhythms are 24-h cycles in physiology regulated by the suprachiasmatic nucleus (SCN) in the brain, where daily cues act on SCN neurons to alter clock timing. …”
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    Cannabinoid Signaling Recruits Astrocytes to Modulate Presynaptic Function in the Suprachiasmatic Nucleus
  8. 21068
    “…INTRODUCTION: Sleep, circadian rhythms, (mental) health, and development are assumed to be intertwined. …”
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    Feasibility of a Complex Setting for Assessing Sleep and Circadian Rhythmicity in a Fragile X Cohort
  9. 21069
    por Mishra, Shova, DiGennaro, Peter
    Publicado 2020
    “…We interrogated RKN biology within the context of host diurnal rhythms throughout nematode development. At 24-hr post-inoculation, RKN penetrated host roots significantly more when inoculated during the night compared to the day. …”
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    Root-knot nematodes demonstrate temporal variation in host penetration
  10. 21070
    “…The molecular clock consists of transcriptional/translational feedback loops that generate rhythms. In mammals, BMAL1 and CLOCK activate rhythmic transcription of genes including the nuclear receptor REV-ERBα, which represses BMAL1 and plays an essential role in sustaining a functional clock. …”
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    Pharmacological activation of the circadian component REV-ERB inhibits HIV-1 replication
  11. 21071
    “…RESULTS: Molecular circadian clocks of the cornea remain in phase with behavioral circadian locomotor rhythms in vivo but are photoentrainable in tissue culture. …”
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    Wounding Induces Facultative Opn5-Dependent Circadian Photoreception in the Murine Cornea
  12. 21072
    “…Short and/or poor sleep are established behavioral factors which can contribute to excess food intake, and emerging evidence suggests that disturbed circadian rhythms may also impact food intake regulation. Together, disturbed sleep and circadian rhythms may help explain the excess risk for obesity seen in shift workers. …”
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    Relationship between Sleep and Hedonic Appetite in Shift Workers
  13. 21073
    “…We also measured the efficiency of CSAC in vivo by assessing circadian rhythms after injecting CSAC into the suprachiasmatic nuclei of Cas9-expressing knock-in mice. …”
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    Multiplexed CRISPR-Cas9 system in a single adeno-associated virus to simultaneously knock out redundant clock genes
  14. 21074
    “…The diurnal expression profile of circRNAs in the rat pineal gland may provide additional information about the role of circRNAs in regulating changes in melatonin circadian rhythms. The analyzed data reported in this study will be an important resource for future studies to elucidate the altered physiology of circRNAs in diurnal rhythms.…”
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    Identifying daily changes in circRNAs and circRNA-associated-ceRNA networks in the rat pineal gland
  15. 21075
    “…Stabilizing adipose tissue rhythms, in turn, may help to combat disrupted energy homeostasis and obesity.…”
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    Contributions of White and Brown Adipose Tissues to the Circadian Regulation of Energy Metabolism
  16. 21076
    “…However, the molecular mechanisms that link the circadian machinery to the action of anticancer treatments is still poorly understood, thus limiting the application of circadian rhythms-driven pharmacological therapy, or chronotherapy, in the clinical practice. …”
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    The Circadian Protein PER1 Modulates the Cellular Response to Anticancer Treatments
  17. 21077
    “…We compare studies on the effects of neonicotinoids on lethality, reproduction, locomotion, immunity, learning, circadian rhythms and sleep in D. melanogaster and a range of pollinators. …”
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    The Power of Drosophila melanogaster for Modeling Neonicotinoid Effects on Pollinators and Identifying Novel Mechanisms
  18. 21078
    por Lobo, Jorge M., Cuesta, Eva
    Publicado 2021
    “…The seasonal and diel variations of dung beetle species were studied in an Iberian mid-mountain locality to examine the interaction between these two temporal rhythms. We assume that a seasonal variation in the diel activity would support the notion that both rhythms may assist in achieving a quick and flexible response when the climatic conditions change. …”
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    Seasonal variation in the diel activity of a dung beetle assemblage
  19. 21079
    “…Theta and gamma rhythms and their cross-frequency coupling play critical roles in perception, attention, learning, and memory. …”
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    Theta-gamma coupling emerges from spatially heterogeneous cholinergic neuromodulation
  20. 21080
    “…Ultradian glucocorticoid rhythms are highly conserved across mammalian species, however, their functional significance is not yet fully understood. …”
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    Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver
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