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  1. 21721
    “…The forebrain knockout mice showed >90% deletion of BMAL1 in the SCN and exhibited an immediate and complete loss of circadian behavior in constant conditions. Circadian rhythms in peripheral tissues persisted but became desynchronized and damped in constant darkness. …”
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    Differential effects of light and feeding on circadian organization of peripheral clocks in a forebrain Bmal1 mutant
  2. 21722
    “…The combined actions of agomelatine on MT1/MT2 and 5-HT2c receptors facilitate the resynchronization of altered circadian rhythms and abnormal sleep patterns. Agomelatine appeared to be effective in treating major depression. …”
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    Agomelatine beyond Borders: Current Evidences of Its Efficacy in Disorders Other than Major Depression
  3. 21723
    “…Melatonin has many important roles in the human physiology: regulator of the circadian rhythms, sleep inducer, antioxidant, anticarcinogenic. …”
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    Role of melatonin in embryo fetal development
  4. 21724
    “…Here, we review implications of this approach for gathering insights into human circadian rhythms and their function in health and disease.…”
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    Human Peripheral Clocks: Applications for Studying Circadian Phenotypes in Physiology and Pathophysiology
  5. 21725
    “…Synchronization of coupled oscillators has been scrutinized for over three centuries, from Huygens' pendulum clocks to physiological rhythms. One such synchronization phenomenon, dynamic mode locking, occurs when naturally oscillating processes are driven by an externally imposed modulation. …”
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    Microscopic dynamics of synchronization in driven colloids
  6. 21726
    por Ng, Fanny S., Jackson, F. Rob
    Publicado 2015
    “…From a glia-specific, RNAi-based genetic screen, we identified eight glial factors that are required for normally robust circadian rhythms in either a light-dark cycle or in constant dark conditions. …”
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    The ROP vesicle release factor is required in adult Drosophila glia for normal circadian behavior
  7. 21727
    “…Biological systems exhibit numerous oscillatory behaviors from calcium oscillations to circadian rhythms that recur daily. These autonomous oscillators contain complex feedbacks with nonlinear dynamics that enable spontaneous oscillations. …”
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    Robustness and period sensitivity analysis of minimal models for biochemical oscillators
  8. 21728
    “…Results indicate that left hemisphere and beta rhythms of electroencephalogram (EEG) signal are sensitive to the cognitive degree of risks in the awareness of information security, which may be probably considered as the sign to assess people's cognition of potential risks in online financial payment.…”
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    Explore Awareness of Information Security: Insights from Cognitive Neuromechanism
  9. 21729
    “…The emergent circadian behavior rhythms free-ran for many cycles under constant conditions without cyclic environmental cues. …”
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    Period-independent novel circadian oscillators revealed by timed exercise and palatable meals
  10. 21730
    “…Although cnidarians exhibit diel behavioral rhythms including cycles in locomotor activity, tentacle extension and spawning, daily cycles in cnidarian metabolism have not been described. …”
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    Daily cycle in oxygen consumption by the sea anemone Nematostella vectensis Stephenson
  11. 21731
    por Mizuno, Takeshi, Yamashino, Takafumi
    Publicado 2015
    “…The circadian clock plays a role in the underlying mechanism for adaptation through generating endogenous rhythms that allow plants to adapt and adjust to both the 24 h diurnal rotation and 365 d seasonal revolution. …”
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    The plant circadian clock looks like a traditional Japanese clock rather than a modern Western clock
  12. 21732
    “…Moreover, the network measures, including degree, degree distribution, local and global efficiency in delta, theta, alpha, and beta rhythms were calculated and analyzed. Results: The local efficiency is higher in the beta frequency and lower in the theta frequency during play task whereas the global efficiency is higher in the theta frequency and lower in the beta frequency in the rest task. …”
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    Combining Partial Directed Coherence and Graph Theory to Analyse Effective Brain Networks of Different Mental Tasks
  13. 21733
    “…Various aspects of the immune system display circadian rhythms. Although lymphocyte trafficking has been suggested to show diurnal variations, the mechanisms and influences on immune responses are unclear. …”
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    Adrenergic control of the adaptive immune response by diurnal lymphocyte recirculation through lymph nodes
  14. 21734
    “…It remains an ongoing investigation about how the neural activity alters with the diurnal rhythms in human brain. Resting-state functional magnetic resonance imaging (RS-fMRI) reflects spontaneous activities and/or the endogenous neurophysiological process of the human brain. …”
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    Diurnal Variations in Neural Activity of Healthy Human Brain Decoded with Resting-State Blood Oxygen Level Dependent fMRI
  15. 21735
    “…A further advance in TMS research applications is the perturbational approach: magnetic pulses can interfere not only with dynamic, often pathological rhythms in epilepsy or altered consciousness states, but also modulate physiological states such as sleep and sleep deprivation. …”
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    New Perspectives in Transcranial Magnetic Stimulation: Epilepsy, Consciousness and the Perturbational Approach
  16. 21736
    “…Hamsters are an ideal animal model for a variety of biomedical research areas such as cancer, virology, circadian rhythms, and behavioural neuroscience. The use of hamsters has declined, however, most likely due to the dearth of genetic tools available for these animals. …”
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    De novo assembly, annotation, and characterization of the whole brain transcriptome of male and female Syrian hamsters
  17. 21737
    “…We conclude that focal ISs interact with normal cortical dynamics far from the epileptic focus, disrupting endogenous oscillatory rhythms and affecting information processing.…”
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    Epileptiform activity in the mouse visual cortex interferes with cortical processing in connected areas
  18. 21738
    “…Thus, entrainment of neonatal prefrontal networks in fast rhythms relies on the activation of layer II/III pyramidal neurons. …”
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    Layer-specific optogenetic activation of pyramidal neurons causes beta–gamma entrainment of neonatal networks
  19. 21739
    “…Locomotor activity rhythms are controlled by a network of ~150 circadian neurons within the adult Drosophila brain. …”
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    RNA-seq analysis of Drosophila clock and non-clock neurons reveals neuron-specific cycling and novel candidate neuropeptides
  20. 21740
    “…An emerging research area is the development of clock-targeting compounds that may serve as drug candidates to correct dysregulated rhythms and hence mitigate disease symptoms and age-related decline. …”
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    Clock-Enhancing Small Molecules and Potential Applications in Chronic Diseases and Aging
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