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21921“…An internal cellular mechanism known as the circadian clock acts as an internal timekeeper that is able to perceive the changes in environmental cues to generate 24-h rhythms in synchronization with daily and seasonal fluctuations. …”
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21922“…While the hippocampus is deemed central to this process, detailed knowledge of which oscillatory rhythms interact in the sleeping human hippocampus is lacking. …”
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21923por Neymotin, Samuel A, Daniels, Dylan S, Caldwell, Blake, McDougal, Robert A, Carnevale, Nicholas T, Jas, Mainak, Moore, Christopher I, Hines, Michael L, Hämäläinen, Matti, Jones, Stephanie R“…Tutorials teach users to simulate commonly measured signals, including event related potentials and brain rhythms. HNN’s ability to associate signals across scales makes it a unique tool for translational neuroscience research.…”
Publicado 2020
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21924por Patel, Nilkanth, Huang, Xi Ping, Grandner, Jessica M, Johansson, Linda C, Stauch, Benjamin, McCorvy, John D, Liu, Yongfeng, Roth, Bryan, Katritch, Vsevolod“…Melatonin receptors MT(1) and MT(2) are involved in synchronizing circadian rhythms and are important targets for treating sleep and mood disorders, type-2 diabetes and cancer. …”
Publicado 2020
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21925por Fajardo, Carlos, De Donato, Marcos, Rodulfo, Hectorina, Martinez-Rodriguez, Gonzalo, Costas, Benjamin, Mancera, Juan Miguel, Fernandez-Acero, Francisco Javier“…Pyrocystis lunula is considered a model organism due to its bioluminescence capacity linked to circadian rhythms. The mechanisms underlying the bioluminescent phenomenon have been well characterized in dinoflagellates; however, there are still some aspects that remain an enigma. …”
Publicado 2020
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21926“…Misalignments between external and internal rhythms, in the short term, traduce into risk of mental and physical performance shortfalls, mood changes, quarrels, drug and alcohol abuse, failure to accomplish with the mission and, finally, high rates of fatal accidents. …”
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21927por Ameneiro, Cristina, Moreira, Tiago, Fuentes-Iglesias, Alejandro, Coego, Alba, Garcia-Outeiral, Vera, Escudero, Adriana, Torrecilla, Daniel, Mulero-Navarro, Sonia, Carvajal-Gonzalez, Jose Maria, Guallar, Diana, Fidalgo, Miguel“…BMAL1 is essential for the regulation of circadian rhythms in differentiated cells and adult stem cells, but the molecular underpinnings of its function in pluripotent cells, which hold a great potential in regenerative medicine, remain to be addressed. …”
Publicado 2020
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21928por Tokuda, Isao T., Schmal, Christoph, Ananthasubramaniam, Bharath, Herzel, Hanspeter“…Understanding entrainment of circadian rhythms is a central goal of chronobiology. Many factors, such as period, amplitude, Zeitgeber strength, and daylength, govern entrainment ranges and phases of entrainment. …”
Publicado 2020
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21929por Singh, Manisha“…It changes in composition with lactation stage and leads to optimal growth of the baby including establishing circadian rhythms, getting protective antibodies, and establishing a healthy gut microbiome. …”
Publicado 2020
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21930“…Many of the circadian rhythms observed in the immune system originate in direct interactions between components of the circadian clock and components of the immune system. …”
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21931“…In addition, intriguing links between hypoxic signaling, circadian rhythms and cell metabolism have been recently discovered, which may provide insights into our fundamental understanding of radioresistance. …”
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21932por Will, Ian, Das, Biplabendu, Trinh, Thienthanh, Brachmann, Andreas, Ohm, Robin A., de Bekker, Charissa“…We propose differentially expressed genes tied to ant neurobiology, odor response, circadian rhythms, and foraging behavior may result by activity of putative fungal effectors such as enterotoxins, aflatrem, and mechanisms disrupting feeding behaviors in the ant.…”
Publicado 2020
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21933por Patton, Andrew P., Edwards, Mathew D., Smyllie, Nicola J., Hamnett, Ryan, Chesham, Johanna E., Brancaccio, Marco, Maywood, Elizabeth S., Hastings, Michael H.“…The hypothalamic suprachiasmatic nuclei (SCN) are the principal mammalian circadian timekeeper, co-ordinating organism-wide daily and seasonal rhythms. To achieve this, cell-autonomous circadian timing by the ~20,000 SCN cells is welded into a tight circuit-wide ensemble oscillation. …”
Publicado 2020
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21934“…In addition to its important role in the regulation of sleep–wake rhythms, several previous studies linked the biologic effects of melatonin to various substantial endocrine, neural, immune and antioxidant functions, among others. …”
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21935por Stagkourakis, Stefanos, Smiley, Kristina O., Williams, Paul, Kakadellis, Sarah, Ziegler, Katharina, Bakker, Joanne, Brown, Rosemary S.E., Harkany, Tibor, Grattan, David R., Broberger, Christian“…Optogenetic manipulation of these rhythms in mice dramatically shifted serum prolactin and paternal behavior, whereas injecting prolactin into non-paternal rat sires triggered expression of parental care. …”
Publicado 2020
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21936por Wood, S. H., Hindle, M. M., Mizoro, Y., Cheng, Y., Saer, B. R. C., Miedzinska, K., Christian, H. C., Begley, N., McNeilly, J., McNeilly, A. S., Meddle, S. L., Burt, D. W., Loudon, A. S. I.“…The annual photoperiod cycle provides the critical environmental cue synchronizing rhythms of life in seasonal habitats. In 1936, Bünning proposed a circadian-based coincidence timer for photoperiodic synchronization in plants. …”
Publicado 2020
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21937“…Melatonin, a pineal hormone, has various physiological functions in the brain, including regulating circadian rhythms, clearing free radicals, inhibiting biomolecular oxidation, and suppressing neuroinflammation. …”
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21938por Alamia, Andrea, Timmermann, Christopher, Nutt, David J, VanRullen, Rufin, Carhart-Harris, Robin L“…Moreover, the typical top-down alpha-band rhythms of closed-eyes rest were significantly decreased, while the bottom-up forward wave was significantly increased. …”
Publicado 2020
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21939“…Circadian rhythms are ubiquitous attributes across living organisms and allow the coordination of internal biological functions with optimal phases of the environment, suggesting a significant adaptive advantage. …”
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21940“…This work highlights the importance of heterogeneity in node dynamics in establishing collective rhythms in complex, excitable networks and has implications for a wide range of real-world systems that exhibit such heterogeneity.…”
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