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21961“…Recent research has highlighted the importance of the body’s various endogenous rhythms in organizing these brain-generated fields through various types of entrainment. …”
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21962por Lamaze, Angelique, Chen, Chenghao, Leleux, Solene, Xu, Min, George, Rebekah, Stanewsky, Ralf“…Daily temporal organisation offers a fitness advantage and is determined by an interplay between environmental rhythms and circadian clocks. While light:dark cycles robustly synchronise circadian clocks, it is not clear how animals experiencing only weak environmental cues deal with this problem. …”
Publicado 2022
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21963por Achom, Mingkee, Roy, Proyash, Lagunas, Beatriz, Picot, Emma, Richards, Luke, Bonyadi-Pour, Roxanna, Pardal, Alonso J, Baxter, Laura, Richmond, Bethany L, Aschauer, Nadine, Fletcher, Eleanor M, Rowson, Monique, Blackwell, Joseph, Rich-Griffin, Charlotte, Mysore, Kirankumar S, Wen, Jiangqi, Ott, Sascha, Carré, Isabelle A, Gifford, Miriam L“…We suggest that rhythmic expression of NCRs may be important for temporal coordination of bacterial activity with the rhythms of the plant host, in order to ensure optimal symbiosis.…”
Publicado 2021
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21964por Liang, Chuqian, Ke, Qiong, Liu, Zunpeng, Ren, Jie, Zhang, Weiqi, Hu, Jianli, Wang, Zehua, Chen, Hong, Xia, Kai, Lai, Xingqiang, Wang, Qiaoran, Yang, Kuan, Li, Wei, Wu, Zeming, Wang, Chao, Yan, Haoteng, Jiang, Xiaoyu, Ji, Zhejun, Ma, Miyang, Long, Xiao, Wang, Si, Wang, Huating, Sun, Hao, Belmonte, Juan Carlos Izpisua, Qu, Jing, Xiang, Andy Peng, Liu, Guang-Hui“…Aging in humans is intricately linked with alterations in circadian rhythms concomitant with physiological decline and stem cell exhaustion. …”
Publicado 2022
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21965por Kong, Yiming, Zhang, Yuxue, Liu, Xiu, Meng, Zhe, Yu, Xiaolin, Zhou, Chuanen, Han, Lu“…LUX ARRHYTHMO (LUX) plays a key role in circadian rhythms and flowering. Here, we identified the MtLUX gene which is the putative ortholog of LUX in Medicago truncatula. …”
Publicado 2022
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21966“…The several isoforms of CK1 take part in key steps of processes including protein translation, cell-cell interactions, synaptic dopaminergic signaling and circadian rhythms. While CK1 mutations are rarely the primary drivers of disease, the kinases are often found to play an accessory role in metabolic disorders and cancers. …”
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21967“…The oscillations exhibit rhythms that are consistent with the state of the art cyanobacteria circadian model, and putative exoelectrogenic pathways. …”
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21968por Schirmer, Catharina, Abboud, Mark A., Lee, Samuel C., Bass, John S., Mazumder, Arindam G., Kamen, Jessica L., Krishnan, Vaishnav“…We find that despite their gait ataxia, stargazer mutants display horizontal hyperactivity and variable rates of repetitive circling behavior. While feeding rhythms, circadian or ultradian oscillations in activity are unchanged, mutants exhibit fragmented bouts of behaviorally defined “sleep”, atypical licking dynamics and lowered sucrose preference. …”
Publicado 2022
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21969por Chun, Sung Kook, Fortin, Bridget M., Fellows, Rachel C., Habowski, Amber N., Verlande, Amandine, Song, Wei A., Mahieu, Alisa L., Lefebvre, Austin E. Y. T., Sterrenberg, Jason N., Velez, Leandro M., Digman, Michelle A., Edwards, Robert A., Pannunzio, Nicholas R., Seldin, Marcus M., Waterman, Marian L., Masri, Selma“…Using patient-derived organoids, we show that circadian rhythms are lost in human tumors. Last, we identify that variance between core clock and Wnt pathway genes significantly predicts the survival of patients with CRC. …”
Publicado 2022
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21970“…Interestingly, animal studies indicate that opioids disrupt sleep/wake behaviors by altering an animal’s ability to synchronize their circadian rhythms to environmental light cycles (i.e., photoentrainment). …”
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21971por Manella, Gal, Ezagouri, Saar, Champigneulle, Benoit, Gaucher, Jonathan, Mendelson, Monique, Lemarie, Emeline, Stauffer, Emeric, Pichon, Aurélien, Howe, Connor A., Doutreleau, Stéphane, Golik, Marina, Verges, Samuel, Asher, Gad“…Recent studies point toward interaction between circadian rhythms and the hypoxic response, yet their human relevance is lacking. …”
Publicado 2022
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21972por Singh, Amit, Li, Congxin, Diernfellner, Axel C. R., Höfer, Thomas, Brunner, Michael“…Our model suggests that functional maturation of the core clock protein Frequency causes a delay in negative feedback that is critical for generating circadian rhythms.…”
Publicado 2022
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21973por Wang, Meiyao, Ge, Jiachun, Ma, Xingkong, Su, Shengyan, Tian, Can, Li, Jianlin, Yu, Fan, Li, Hongxia, Song, Changyou, Gao, Jiancao, Xu, Pao, Tang, Yongkai, Xu, Gangchun“…DEGs were also related to the regulation of glutathione homeostasis and biological rhythms in regard to anti-oxidation and anti-aging, and to the regulation of immune cell development and the immune response. …”
Publicado 2022
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21974por Smieszek, Sandra P., Polymeropoulos, Christos M., Birznieks, Gunther, Polymeropoulos, Mihael H.“…Mutations in OPN4 were shown to affect responses to light, ultimately affecting the regulation of circadian rhythms and sleep. In this study, we describe a male carrier of the OPN4 missense variant diagnosed with delayed sleep-wake phase disorder (DSWPD), with a consistent recurrent pattern of delayed sleep onset The rs143641898 [NM_033282.4:c.502C>T p.…”
Publicado 2022
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21975“…Light modulates human brain function through its effect on circadian rhythms, which are related to several human behavioral and physiological processes. …”
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21976“…Deciding whether to engage in strenuous mental activities requires trading-off the potential benefits against the costs of mental effort, but it is unknown which brain rhythms are causally involved in such cost-benefit calculations. …”
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21977“…Dinoflagellates are unicellular, photosynthetic, primarily marine eukaryotes are known for their unique biology and rhythmic physiology. Their physiological rhythms are driven by an internal oscillator whose molecular underpinnings are yet unknown. …”
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21978por Pedrosa, Rafael, Nazari, Mojtaba, Mohajerani, Majid H., Knöpfel, Thomas, Stella, Federico, Battaglia, Francesco P.“…Hippocampal slow gamma rhythms were strongly associated to neocortical transients, even more than ripples. …”
Publicado 2022
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21979por Park, JuYoung, Sullivan, Marlysa, Heilman, Keri, Surage, Jayshree, Levine, Hannah, Hung, Lillian, Ortega, María“…This study assessed the feasibility of a remotely supervised online chair yoga (CY) intervention for older adults with dementia, exploring preliminary effects of CY on chronic pain, mobility, risk of falling, sleep disturbance, autonomic reactivity, cardiac rhythms (using IOM2 biofeedback device), and loneliness in this population. …”
Publicado 2022
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21980“…The importance of circadian rhythms in human health and disease calls for a thorough understanding of the underlying molecular machinery, including its key components, the flavin adenine dinucleotide (FAD)-containing flavoproteins cryptochrome 1 and 2. …”
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